A parametric design-based methodology to visualize building performance at the neighborhood scale

This paper focuses on parametric design-based visualization methods to represent building performance at the neighborhood scale in the perspective of an integrated design-support system. The goal of the developed methodology is to convey the relative effectiveness of different design alternatives according to a wide range of building performance indicators, including the potential for active solar applications, the energy need for space heating/cooling and (spatial) daylight autonomy. The proposed methodology is applied to a case study of a typical urban renewal project in Switzerland for which 768 design variants were analyzed using validated climate-based simulation engines. For each design variant, simulation results are represented qualitatively using multiple false-color maps and quantitatively through comprehensive plots. We conclude by showing the applicability of this methodology to a large number of neighborhood-scale design variants as well as the complementarity of the proposed visualization methods. On the basis of the case study application, a possible implementation as a design-support tool is finally discussed

Ebola response missions: To go or not to go? Crosssectional study on the motivation of European public health experts, December 2014

We surveyed European infectious disease epidemiologists and microbiologists about their decisions to apply for Ebola response missions. Of 368 respondents, 49 (15%) had applied. Applicants did not differ from non-applicants in terms of age, sex or profession but had more training in field epidemiology and more international experience. Common concerns included lack of support from families and employers. Clearer terms of reference and support from employers could motivate application and support outbreak response in West Africa

Shame in Parkinson'S Disease: A Review

Shame is a self-conscious emotion marked by an intensely negative self-evaluation. It is exhibited by an individual upon realizing that she/he has violated an important (usually social) norm. Shame can be a source of emotional distress leading to social withdrawal and depression, with a significant negative impact on quality of life. In Parkinson's disease (PD), shame is rarely addressed. Based on reports of persons affected with Parkinson's disease (PwP) as well as a literature review, this article describes PD-related shame. PD-related shame may emerge from motor and non-motor symptoms, from self-perception of inadequacy due to loss of autonomy and need for help, or from perceived deterioration of body image. The neurobiology of shame delineates neuronal networks involved in cognitive and emotions regulation, self-representation and representation of the others mental states. Although this hypothesis remains to be demonstrated, these substrates could be modulated, at least partially, by dopaminergic depletion related to PD, which may open a window for pharmacotherapy. Owing to the negative impact that shame can produce, shame should be actively explored and addressed in the individual PwP. Teaching PwP how to develop resilience to shame may be a useful strategy in preventing the vicious circle of shame. The paucity of existing data on prevalence and management of PD-specific shame contrasts with the manifold reported situations inducing suffering from shame. There is a crucial need for further investigations of shame in PD and the development of interventions to reduce its impact on PwP's quality of life

Early findings in outbreak of haemolytic uraemic syndrome among young children caused by Shiga toxin-producing Escherichia coli, Romania, January to February 2016

As at 29 February 2016, 15 cases of haemolytic uraemic syndrome with onset between 25 January and 22 February were reported among children between five and 38 months in Romania, and three of them died. Cases were mostly from southern Romania. Six cases tested positive for Escherichia coli O26 by serology. Fruits, vegetables, meat and dairy products were among the possible common food exposures. Investigations are ongoing in Romania to control the outbreak

Unravelling the along-strike variability of the Angola–Gabon rifted margin: a mapping approach

International audienc

Short pulse width in subthalamic stimulation in Parkinson's disease: a randomized, double-blind study

We investigated the acute effect of short pulse widths on the therapeutic window in subthalamic nucleus deep brain stimulation in Parkinson's disease

Origin and evolution of the Kolbeinsey Ridge and Iceland Plateau, N-Atlantic

Variations in crustal structure along the 700 km long KRISE7 refraction/reflection and gravity profile, straddling 66.5 degrees N across the Iceland Shelf, Iceland Plateau and western Norway Basin confirm that extinct spreading centers coexisted with the now extinct aegir Ridge prior to the initiation of the Kolbeinsey Ridge at 26 Ma. The western 300 km of the profile, across the Iceland shelf, formed by rifting at the Kolbeinsey Ridge, whereas the eastern 400 km, across the Iceland Plateau and the western Norway Basin, formed by earlier rifting, possibly containing slivers of older oceanic or continental crust rifted off the central E-Greenland margin along with the Jan Mayen Ridge. Crustal thickness increases gradually across the Iceland shelf, from 12 to 13 km near the Kolbeinsey Ridge to 24-28 km near the eastern shelf edge, decreasing abruptly across the shelf edge, to 12-13 km. The Iceland Plateau has crustal thickness ranging from 12 to 15 km decreasing to 5-8 km across the western Norway Basin and 4-5 km at the aegir Ridge. We suggest that high-velocity lower crustal domes and corresponding gravity highs across the Iceland plateau mark the location of extinct rift axes that coexisted with the aegir Ridge. Similar lower crustal domes are associated with the currently active rift segments within Iceland and the Kolbeinsey Ridge

The World Health Organization’s public health intelligence activities during the COVID-19 pandemic response, December 2019 to December 2021

The coronavirus disease (COVID-19) presented a unique opportunity for the World Health Organization (WHO) to utilise public health intelligence (PHI) for pandemic response. WHO systematically captured mainly unstructured information (e.g. media articles, listservs, community-based reporting) for public health intelligence purposes. WHO used the Epidemic Intelligence from Open Sources (EIOS) system as one of the information sources for PHI. The processes and scope for PHI were adapted as the pandemic evolved and tailored to regional response needs. During the early months of the pandemic, media monitoring complemented official case and death reporting through the International Health Regulations mechanism and triggered alerts. As the pandemic evolved, PHI activities prioritised identifying epidemiological trends to supplement the information available through indicator-based surveillance reported to WHO. The PHI scope evolved over time to include vaccine introduction, emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, unusual clinical manifestations and upsurges in cases, hospitalisation and death incidences at subnational levels. Triaging the unprecedented high volume of information challenged surveillance activities but was managed by collaborative information sharing. The evolution of PHI activities using multiple sources in WHO’s response to the COVID-19 pandemic illustrates the future directions in which PHI methodologies could be developed and used.</jats:p

World Health Organization (WHO) criteria for selecting potential signals.

World Health Organization (WHO) criteria for selecting potential signals.</p