Resistência a antimicrobianos de amostras de Escherichia coli isoladas de esterqueiras para o tratamento de dejetos suínos

01

Patterns of homozygosity in insular and continental goat breeds

Genetic isolation of breeds may result in a significant loss of diversity and have consequences on health and performance. In this study, we examined the effect of geographic isolation on caprine genetic diversity patterns by genotyping 480 individuals from 25 European and African breeds with the Goat SNP50 BeadChip and comparing patterns of homozygosity of insular and nearby continental breeds. Among the breeds analysed, number and total length of ROH varied considerably and depending on breeds, ROH could cover a substantial fraction of the genome (up to 1.6 Gb in Icelandic goats). When compared with their continental counterparts, goats from Iceland, Madagascar, La Palma and Ireland (Bilberry and Arran) displayed a significant increase in ROH coverage, ROH number and F values (P value < 0.05). Goats from Mediterranean islands represent a more complex case because certain populations displayed a significantly increased level of homozygosity (e.g. Girgentana) and others did not (e.g. Corse and Sarda). Correlations of number and total length of ROH for insular goat populations with the distance between islands and the nearest continental locations revealed an effect of extremely long distances on the patterns of homozygosity. These results indicate that the effects of insularization on the patterns of homozygosity are variable. Goats raised in Madagascar, Iceland, Ireland (Bilberry and Arran) and La Palma, show high levels of homozygosity, whereas those bred in Mediterranean islands display patterns of homozygosity that are similar to those found in continental populations. These results indicate that the diversity of insular goat populations is modulated by multiple factors such as geographic distribution, population size, demographic history, trading and breed management. The online version of this article (10.1186/s12711-018-0425-7) contains supplementary material, which is available to authorized users

AdaptMap: exploring goat diversity and adaptation

Not presen

Differential expression of mRNA isoforms in the skeletal muscle of pigs with distinct growth and fatness profiles

Transcript diversity in the <i>gluteus medius</i> muscle of pigs and mRNA isoforms that are differentially expressed in Duroc swine with distinct growth and fatness profile

Plano Diretor de Niterói: conflitos e disputas

A presente dissertação investiga e problematiza a construção do Plano Diretor na Cidade de Niterói com foco no processo de participação popular. Busca conhecer o processo de elaboração do projeto desvendando de que forma o Município garantiu a efetiva participação popular dos cidadãos e busca, ainda, compreender a efetividade das audiências públicas que é um instrumento que se encontram até apresente data com baixa densidade normativa. Investiga como se deu a construção do Plano Diretor com foco na fase legislativa e averigua a participação popular e a construção/mudanças a partir da entrada do Plano Diretor na Câmara. Versa sobre as audiências públicas do Plano Diretor Participativo (PDP), entendido como instrumento de efetividade da gestão democrática e de exercício do direito à cidade. O objetivo é compreender as potencialidades e as limitações dos dispositivos legais que regem o PDP, no que concerne ao papel da coletividade nas audiências públicas, tendo em conta as distorções observadas na prática desse instrumento participativo. Observa, também, as aplicações das resoluções estabelecidas pelo Ministério das Cidades. Para cumprir esse último objetivo, foram adotados três procedimentos metodológicos: (i) interpretação do regime legal das audiências, a partir dos conceitos operacionais fornecidos pelo marco teórico adotado, sobretudo e (ii) investigação das normas aplicáveis às audiências públicas do PDP, no contexto das inovações trazidas pela Constituição de 1988 e da legislação infraconstitucional, que trata da participação popular para gestão do meio ambiente natural e urbano. A partir de um método de interpretação teleológico dos princípios constitucionais e legais, averiguou-se a integração dos novos direitos sociais e coletivos à luz do marco conceitual consolidado pelo Estatuto da Cidade. Interessou, ainda, avaliar como a norma foi compreendida e aplicada em concreto em Niterói, de modo a visualizar quais as principais distorções e inconsistências na relação entre os partícipes do processo e a norma. Embora o caráter participativo das audiências públicas represente uma importante conquista histórica, foi possível concluir que esse instrumento ainda carece de densidade normativa. A falta de abrangência normativa sobre o propósito da audiência e de diretrizes para sua condução facilita distorções e tende a reduzir sua legitimidade políticaThis dissertation investigates and calls into question the creation of the Master Plan for the City of Niterói focused on the process of popular participation. It seeks to learn about the designing process by pointing out how the City ensured the citizens‘ popular participation and also aims to understand the effectiveness of the public hearings which has been an instrument with a low normative density so far. It investigates how the construction of the Master Plan was conceived focusing on the legislative phase and looks into the popular participation and the construction/changes as soon as the Master Plan is submitted to the Chamber. It analyzes the public hearings on the Participatory Master Plan (PDP), which is viewed as an instrument to enforce democratic management and the exercise of the right to citizenship. The purpose is to understand the powers and restrictions of the legal provisions which govern the PDP, with regard to the population‘s role at public hearings, on account of the distortions observed in the practice of this participatory instrument. It also observes the applicability of the resolutions laid down by the Ministry of the Cities. To fulfill this latter goal, three methodological procedures were introduced:(i) interpretation of the legal basis for the hearings, according to the operating concepts provided by the theoretical grounds adopted, most of all and (ii) investigation into the rules applicable to the public hearings on the PDP, in relation to the innovations introduced by the 1988 Constitution, international treaties and the infraconstitutional legislation, which addresses the popular participation in the management of the natural and urban environment. Based on a teleologic construal of the constitutional and legal principles, the integration of the new social and collective rights was examined in light of the conceptual basis consolidated by the Statute of the City. It was also assessed how the rule was construed and actually applied in Niterói, in order to view the main distortions and inconsistencies found in the relationship between the elements of the process and the rule. Although the participatory nature of the public hearings represents an important historical conquest, it was possible to conclude that this instrument still wants normative density. The lack of normative scope as to the purpose of the hearings and guidelines on their procedures enable distortions and undermine their political legitimacy117 f

Resistência a antimicrobianos de amostras de Escherichia coli isoladas de esterqueiras para o tratamento de dejetos suínos

01

Sobrevivência e perfil de resistência antimicrobiana de amostras de Salmonella sp. isoladas em esterqueiras para o tratamento de dejetos suínos

01

Destruction of naphthalene via ozone-catalytic oxidation process over Pt/Al2O3 catalyst

The genetic factors determining the phenotypic variation of porcine fatness phenotypes are still largely unknown. We investigated whether the polymorphism of eight genes (MIGA2, CRY2, NPAS2, CIART, ARNTL2, PER1, PER2 and PCK1), which display diferential expression in the skeletal muscle of fasted and fed sows, is associated with the variation of lipid and mRNA expression phenotypes in Duroc pigs. The performance of an association analysis with the GEMMA software demonstrated that the rs330779504 SNP in the MIGA2 gene is associated with LDL concentration at 190 days (LDL2, corrected P-value=0.057). Moreover, the rs320439526 SNP of the CRY2 gene displayed a signifcant association with stearic acid content in the longissimus dorsi muscle (LD C18:0, corrected P-value=0.015). Both SNPs were also associated with the mRNA levels of the corresponding genes in the gluteus medius skeletal muscle. From a biological perspective these results are meaningful because MIGA2 protein plays an essential role in mitochondrial fusion, a process tightly connected with the energy status of the cell, while CRY2 is a fundamental component of the circadian clock. However, inclusion of these two SNPs in chromosome-wide association analyses demonstrated that they are not located at the peaks of signifcance for the two traits under study (LDL2 for rs330779504 and LD C18:0 for rs320439526), thus implying that these two SNPs do not have causal efects.info:eu-repo/semantics/publishedVersio