201 research outputs found

    Housing For The People: A Tenant Opportunity to Purchase Act for New York City

    Get PDF

    Population dynamics of tundra swans on the lower Alaska Peninsula

    Get PDF
    Thesis (M.S.) University of Alaska Fairbanks, 2007This study was initiated in response to concerns regarding apparent declines in abundance and breeding pair density of tundra swans on and adjacent to Izembek National Wildlife Refuge (NWR) on the lower Alaska Peninsula. I conducted an analysis of long-term data (1978-1996) to estimate demographic parameters and assess the relationship between survival probabilities and a number of environmental and ecological factors. Rates of productivity (egg, nest, cygnet survival) and annual rates of apparent adult survival were lower and more variable than previously observed for other swan populations and species. A negative relationship between nesting success and brown bear density indicates that depredation by bears is a primary determinant of tundra swan reproductive success. Changes in apparent survival probability were primarily influenced by high and variable rates of permanent emigration. Because of low rates of production and apparent survival, immigration by swans from other breeding areas may be important for sustaining a breeding population of tundra swans on and adjacent to Izembek NWR.Productivity of tundra swans breeding on the lower Alaska Peninsula -- Age-specific survival of tundra swans along the lower Alaska Peninsula

    The Use of Knowledge Management Methodologies to Improve the Practice of Supply Chain Management: The Case of the Bullwhip Effect

    Get PDF
    Supply Chain Management is a critically important approach toward producing and delivering goods and services in a cost-effective, timely manner. However, many SCM systems in practice exhibit the bullwhip effect, a tendency towards increasing variability in demand as this type of information migrates downwards in the producing supply chain. We argue that one can reduce the size of the bullwhip effect through the judicious use of knowledge management technologies. We have advanced our arguments through several propositions, and we have derived a set of testable hypotheses from two of these propositions in order to demonstrate how one would go about verifying these arguments. We have identified two different general research methodologies in order to provide a multiple methodological approach to gaining greater confidence in the propositions. It now remains to carry out this plan of research

    Activation and inhibition of phosphorylase kinase by monospecific antibodies raised against peptides from the regulatory domain of the γ-subunit

    Get PDF
    The C terminus of the catalytic γ-subunit of phosphorylase kinase comprises a regulatory domain that contains regions important for subunit interactions and autoinhibitory functions. Monospecific antibodies raised against four synthetic peptides from this region, PhK1 (362-386), PhK5 (342-366), PhK9 (322-346) and PhK13 (302-326), were found to have significant effects on the catalytic activities of phosphorylase kinase holoenzyme and the γ•δ complex. Antibodies raised against the very C terminus of the γ-subunit, anti-PhK1 and anti-PhK5, markedly activated both holoenzyme and the γ•δ complex, in the presence and absence of Ca2+. In the presence of Ca2+ at pH 8.2, anti-PhK1 activated the holoenzyme more than 11-fold and activated the γ•δ complex 2.5-fold. Activation of the holoenzyme and the γ•δ complex by anti-PhK5 was 50-70 % of that observed with anti-PhK1. Prior phosphorylation of the holoenzyme by the cAMP-dependent protein kinase blocked activation by both anti-PhK1 and anti-PhK5. Antibodies raised against the peptides from the N terminus of the regulatory domain, anti-PhK9 and anti-PhK13, were inhibitory, with their greatest effects on the γ•δ complex. These data demonstrate that the binding of antibodies to specific regions within the regulatory domain of the γ-subunit can augment or inhibit structural changes and subunit interactions important in regulating phosphorylase kinase activity

    Value-driven partner search for <i>Energy from Waste</i> projects

    Get PDF
    Energy from Waste (EfW) projects require complex value chains to operate effectively. To identify business partners, plant operators need to network with organisations whose strategic objectives are aligned with their own. Supplier organisations need to work out where they fit in the value chain. Our aim is to support people in identifying potential business partners, based on their organisation’s interpretation of value. Value for an organisation should reflect its strategy and may be interpreted using key priorities and KPIs (key performance indicators). KPIs may comprise any or all of knowledge, operational, economic, social and convenience indicators. This paper presents an ontology for modelling and prioritising connections within the business environment, and in the process provides means for defining value and mapping these to corresponding KPIs. The ontology is used to guide the design of a visual representation of the environment to aid partner search

    Inclusive Recovery in US Cities

    Get PDF
    Some cities have harnessed economic recoveries to improve on inclusion, or the opportunity for all residents—particularly historically excluded populations—to benefit from and contribute to economic prosperity. In this report, we conduct the first empirical analysis of how economic health and inclusion interact in US cities over several decades. We report on trends in economic health and inclusion across many cities and within a smaller subset of cities that have experienced an economic recovery. To better understand whether and how an economic recovery can support inclusive outcomes, we delve deeper into four cities that improved on inclusion measures during their recovery. Through discussions with individuals, an in-person convening, and a review of literature, we identify key lessons and common building blocks that can support progress on inclusion during a city's economic recovery

    Analysis of global manufacturing virtual networks in the aeronautical industry

    Get PDF
    The evolution of organizations that work in multinational environments has considerably altered their production strategies. One of the consequences has been the appearance of Global Manufacturing Virtual Networks (GMVNs), which include all kinds of enterprises and production centres and establish a new type of horizontal collaboration and relations between independent companies and even competitors who establish occasional collaborations on projects they could not take on individually. This paper analyses the causes behind the formation of such networks, their strategy, structure, dynamics and evolution, taking into account areas such as strategic intercompany alliances, synchronization of their value and supply chains, their information systems, the cultural aspects of the organizations in question and, finally, their convergence with another of the more relevant future trends in production: mass customization. The proposed model shall be applied to the aeronautical industry which is one of the industries which has developed the GMVN concept. The case study of the engine manufacturer Rolls Royce will provide a better understanding of the evolution of its strategic positioning, as well as the dynamic and fluent nature of its virtual relations. This will demonstrate its effectiveness by clarifying and putting these organizations in perspective and analyzing their evolution over the next few year

    Supply Chain Intelligence

    Get PDF
    This chapter provides on overall picture of business intelligence (BI) and supply chain analytics (SCA) as a means to support supply chain management (SCM) and decision-making. Based on the literature review, we clarify the needs of BI and performance measurement in the SCM sphere, and discuss its potential to enhance decision-making in strategic, tactical and operational levels. We also make a closer look in to SCA in different areas and functions of SCM. Our findings indicate that the main challenge for harnessing the full potential of SCA is the lack of holistic and integrated BI approaches that originates from the fact that each functional area is using its own IT applications without necessary integration in to the company’s overall BI system. Following this examination, we construct a holistic framework that illustrates how an integrated, managerially planned BI system can be developed. Finally, we discuss the main competency requirements, as well as the challenges still prohibiting the great majority of firms from building smart and comprehensive BI systems for SCM.fi=vertaisarvioitu|en=peerReviewed

    Detection, prevalence, and transmission of avian hematozoa in waterfowl at the Arctic/sub-Arctic interface: co-infections, viral interactions, and sources of variation

    Get PDF
    Background The epidemiology of avian hematozoa at high latitudes is still not well understood, particularly in sub-Arctic and Arctic habitats, where information is limited regarding seasonality and range of transmission, co-infection dynamics with parasitic and viral agents, and possible fitness consequences of infection. Such information is important as climate warming may lead to northward expansion of hematozoa with unknown consequences to northern-breeding avian taxa, particularly populations that may be previously unexposed to blood parasites. Methods We used molecular methods to screen blood samples and cloacal/oropharyngeal swabs collected from 1347 ducks of five species during May-August 2010, in interior Alaska, for the presence of hematozoa, Influenza A Virus (IAV), and IAV antibodies. Using models to account for imperfect detection of parasites, we estimated seasonal variation in prevalence of three parasite genera (Haemoproteus, Plasmodium, Leucocytozoon) and investigated how co-infection with parasites and viruses were related to the probability of infection. Results We detected parasites from each hematozoan genus in adult and juvenile ducks of all species sampled. Seasonal patterns in detection and prevalence varied by parasite genus and species, age, and sex of duck hosts. The probabilities of infection for Haemoproteus and Leucocytozoon parasites were strongly positively correlated, but hematozoa infection was not correlated with IAV infection or serostatus. The probability of Haemoproteus infection was negatively related to body condition in juvenile ducks; relationships between Leucocytozoon infection and body condition varied among host species. Conclusions We present prevalence estimates for Haemoproteus, Leucocytozoon, and Plasmodium infections in waterfowl at the interface of the sub-Arctic and Arctic and provide evidence for local transmission of all three parasite genera. Variation in prevalence and molecular detection of hematozoa parasites in wild ducks is influenced by seasonal timing and a number of host traits. A positive correlation in co-infection of Leucocytozoon and Haemoproteus suggests that infection probability by parasites in one or both genera is enhanced by infection with the other, or that encounter rates of hosts and genus-specific vectors are correlated. Using size-adjusted mass as an index of host condition, we did not find evidence for strong deleterious consequences of hematozoa infection in wild ducks.Geological Survey (U.S.) (Wildlife Program of the Ecosystem Mission Area)U.S. Fish and Wildlife ServiceDelta Waterfowl FoundationInstitute for Wetland and Waterfowl ResearchIcahn School of Medicine at Mount Sinai (Center for Research on Influenza Pathogenesis)Center of Excellence for Influenza Research and Surveillance (contracts HHSN272201400008C and HHSN266200700010C
    • …
    corecore