509 research outputs found
Implementing Performance Competitive Logical Recovery
New hardware platforms, e.g. cloud, multi-core, etc., have led to a
reconsideration of database system architecture. Our Deuteronomy project
separates transactional functionality from data management functionality,
enabling a flexible response to exploiting new platforms. This separation
requires, however, that recovery is described logically. In this paper, we
extend current recovery methods to work in this logical setting. While this is
straightforward in principle, performance is an issue. We show how ARIES style
recovery optimizations can work for logical recovery where page information is
not captured on the log. In side-by-side performance experiments using a common
log, we compare logical recovery with a state-of-the art ARIES style recovery
implementation and show that logical redo performance can be competitive.Comment: VLDB201
Perspects in astrophysical databases
Astrophysics has become a domain extremely rich of scientific data. Data
mining tools are needed for information extraction from such large datasets.
This asks for an approach to data management emphasizing the efficiency and
simplicity of data access; efficiency is obtained using multidimensional access
methods and simplicity is achieved by properly handling metadata. Moreover,
clustering and classification techniques on large datasets pose additional
requirements in terms of computation and memory scalability and
interpretability of results. In this study we review some possible solutions
Anti-angiogenic VEGFAxxxb transcripts are not expressed in the medio-basal hypothalamus of the seasonal sheep
Source at https://doi.org/10.1371/journal.pone.0197123.This study investigated Vegfa expression in the pars tuberalis (PT) of the pituitary and medio-basal hypothalamus (MBH) of sheep, across seasons and reproductive states. It has recently been proposed that season impacts alternative splicing of Vegfa mRNA in the PT, which shifts the balance between angiogenic VEGFAxxx and anti-angiogenic VEGFAxxxb isoforms (with xxx the number of amino acids of the mature VEGFA proteins) to modulate seasonal breeding. Here, we used various RT-PCR methodologies and analysis of RNAseq datasets to investigate seasonal variation in expression and splicing of the ovine Vegfa gene. Collectively, we identify 5 different transcripts for Vegfa within the ewe PT/MBH, which correspond to splicing events previously described in mouse and human. All identified transcripts encode angiogenic VEGFAxxx isoforms, with no evidence for alternative splicing within exon 8. These findings led us to investigate in detail how âVegfaxxxb-likeâ PCR products could be generated by RT-PCR and misidentified as endogenous transcripts, in sheep and human HEK293 cells. In conclusion, our findings do not support the existence of anti-angiogenic VEGFAxxxb isoforms in the ovine PT/MBH and shed new light on the interpretation of prior studies, which claimed to identify Vegfaxxxb isoforms by RT-PCR
06121 Abstracts Collection -- Atomicity: A Unifying Concept in Computer Science
From 19.03.06 to 24.03.06, the Dagstuhl Seminar 06121 ``Atomicity: A Unifying Concept in Computer Science\u27\u27 was held in the International Conference and Research Center (IBFI), Schloss Dagstuhl.
During the seminar, several participants presented their current
research, and ongoing work and open problems were discussed. Abstracts of
the presentations given during the seminar as well as abstracts of
seminar results and ideas are put together in this paper. The first section
describes the seminar topics and goals in general.
Links to extended abstracts or full papers are provided, if available
Lâemploi de lâhumour en classe de FLE dans le cadre de lâenseignement de la culture : crĂ©ation dâactivitĂ©s
Lâ« Enseignement de la culture en classe de FLE » Ă©tait lâun des titres proposĂ©s
pour la rédaction du mémoire, en spécialité de français. En choisissant de travailler sur
lâhumour en classe de FLE, je ne mâĂ©loigne pas du thĂšme gĂ©nĂ©ral « la culture ». En
effet, lâhumour contient certes des valeurs communes Ă toutes les sociĂ©tĂ©s et tous les
pays, par exemple le rire physiologique est universel, mais lâhumour contient Ă©galement
des charges culturelles et sĂ©mantiques liĂ©es Ă un mĂȘme groupe. Nous pouvons donc dire
que lâhumour est aussi bien liĂ© Ă lâhistoire, quâĂ la littĂ©rature, la politique, lâart, la
langue⊠Et tout cela forme la culture dâun pays. Alors pourquoi semble-t-il autant
dĂ©laissĂ© de lâenseignement traditionnel ? Ce dernier fait souvent appel, peut-ĂȘtre trop,
aux manuels scolaires et ne sâen dĂ©tache pas. Cela ne serait pas le problĂšme si les
manuels avaient recours Ă la culture francophone, dont lâhumour, de façon plus
dĂ©taillĂ©e. Or les manuels scolaires nâont pas encore intĂ©grĂ© lâhumour francophone, ou de
façon trĂšs sporadique, dans leurs contenus.Departamento de FilologĂa Francesa y AlemanaMĂĄster en Profesor de EducaciĂłn Secundaria Obligatoria y Bachillerato, FormaciĂłn Profesional y Enseñanzas de Idioma
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