10,038 research outputs found

    Mantle flow and lithosphere-asthenosphere coupling beneath the southwestern edge of the North American craton: constraints from shear-wave splitting measurements

    Get PDF
    High-quality broadband seismic data recorded by the USArray and other stations in the southwestern United States provide a unique opportunity to test different models of anisotropy-forming mechanisms in the vicinity of a cratonic edge. Systematic spatial variations of anisotropic characteristics are revealed by 3027 pairs of splitting parameters measured at 547 broadband seismic stations. The western and southern edges of the North American craton show edge-parallel fast directions with larger-than-normal splitting times, and the continental interior is characterized by smaller splitting times spatially consistent fast directions that are mostly parallel to the absolute plate motion direction of North America. Except for a small area in the vicinity of the Llano Uplift in central Texas, no systematic azimuthal variations of the splitting parameters are observed, suggesting that a single layer of anisotropy with horizontal axis of symmetry can adequately explain the observations. Estimation of the depth of the source of the observed anisotropy using spatial coherency of the splitting parameters indicates that the observed anisotropy mostly originate from the upper asthenosphere, through simple shear between the partially coupled lithosphere and asthenosphere --Abstract, page iv

    Demographic inference from multiple whole genomes using a particle filter for continuous Markov jump processes

    Get PDF
    Demographic events shape a population's genetic diversity, a process described by the coalescent-with-recombination model that relates demography and genetics by an unobserved sequence of genealogies along the genome. As the space of genealogies over genomes is large and complex, inference under this model is challenging. Formulating the coalescent-with-recombination model as a continuous-time and -space Markov jump process, we develop a particle filter for such processes, and use waypoints that under appropriate conditions allow the problem to be reduced to the discrete-time case. To improve inference, we generalise the Auxiliary Particle Filter for discrete-time models, and use Variational Bayes to model the uncertainty in parameter estimates for rare events, avoiding biases seen with Expectation Maximization. Using real and simulated genomes, we show that past population sizes can be accurately inferred over a larger range of epochs than was previously possible, opening the possibility of jointly analyzing multiple genomes under complex demographic models. Code is available at https://github.com/luntergroup/smcsmc.

    A new criteria for zero quantum discord

    Full text link
    We propose a new criterion to judge zero quantum discord for arbitrary bipartite states. A bipartite quantum state has zero quantum discord if and only if all blocks of its density matrix are normal matrices and commute with each other. Given a bipartite state with zero quantum discord, how to find out the set of local projectors, which do not disturb the whole state after being imposed on one subsystem, is also presented. A class of two-qubit X-state is used to test the criterion, and an experimental scheme is proposed to realize it. Consequently, we prove that the positive operator-valued measurement can not extinguish the quantum correlation of a bipartite state with nonzero quantum discord.Comment: 10 pages, 1 figur

    Long-range depth imaging using a single-photon detector array and non-local data fusion

    Get PDF
    The ability to measure and record high-resolution depth images at long stand-off distances is important for a wide range of applications, including connected and automotive vehicles, defense and security, and agriculture and mining. In LIDAR (light detection and ranging) applications, single-photon sensitive detection is an emerging approach, offering high sensitivity to light and picosecond temporal resolution, and consequently excellent surface-to-surface resolution. The use of large format CMOS (complementary metal-oxide semiconductor) single-photon detector arrays provides high spatial resolution and allows the timing information to be acquired simultaneously across many pixels. In this work, we combine state-of-the-art single-photon detector array technology with non-local data fusion to generate high resolution three-dimensional depth information of long-range targets. The system is based on a visible pulsed illumination system at a wavelength of 670 nm and a 240 × 320 array sensor, achieving sub-centimeter precision in all three spatial dimensions at a distance of 150 meters. The non-local data fusion combines information from an optical image with sparse sampling of the single-photon array data, providing accurate depth information at low signature regions of the target

    A globally consistent nonlinear least squares estimator for identification of nonlinear rational systems

    Get PDF
    © 2016 Elsevier Ltd This paper considers identification of nonlinear rational systems defined as the ratio of two nonlinear functions of past inputs and outputs. Despite its long history, a globally consistent identification algorithm remains illusive. This paper proposes a globally convergent identification algorithm for such nonlinear rational systems. To the best of our knowledge, this is the first globally convergent algorithm for the nonlinear rational systems. The technique employed is a two-step estimator. Though two-step estimators are known to produce consistent nonlinear least squares estimates if a N consistent estimate can be determined in the first step, how to find such a N consistent estimate in the first step for nonlinear rational systems is nontrivial and is not answered by any two-step estimators. The technical contribution of the paper is to develop a globally consistent estimator for nonlinear rational systems in the first step. This is achieved by involving model transformation, bias analysis, noise variance estimation, and bias compensation in the paper. Two simulation examples and a practical example are provided to verify the good performance of the proposed two-step estimator

    Physical Modelling and Similitude of Air Bubble Entrainment at Vertical Circular Plunging Jets

    Get PDF
    When a plunging jet impinges into a pool of liquid, air bubble entrainment takes place if the inflow velocity exceeds a threshold velocity. This study investigates air entrainment and bubble dispersion in the developing flow region of vertical circular plunging jets. Three scale models were used and detailed air-water measurements (void fraction, bubble count rate, bubble sizes) were performed systematically for identical inflow Froude numbers. The results highlight that the modelling of plunging jet based upon a Froude similitude is affected by significant scale effects when the approach flow conditions satisfied We1 1E+3. Bubble chord time measurements showed pseudo-chord sizes of entrained bubbles ranging from less than 0.5 mm to more than 10 mm with an average pseudo-chord size were between 4 and 9 mm. However bubble size data could not be scaled properly

    Spitzer IRAC Photometry for Time Series in Crowded Fields

    Get PDF
    We develop a new photometry algorithm that is optimized for SpitzerSpitzer time series in crowded fields and that is particularly adapted to faint and/or heavily blended targets. We apply this to the 170 targets from the 2015 SpitzerSpitzer microlensing campaign and present the results of three variants of this algorithm in an online catalog. We present detailed accounts of the application of this algorithm to two difficult cases, one very faint and the other very crowded. Several of SpitzerSpitzer's instrumental characteristics that drive the specific features of this algorithm are shared by KeplerKepler and WFIRSTWFIRST, implying that these features may prove to be a useful starting point for algorithms designed for microlensing campaigns by these other missions.Comment: accepted for publication in The Astrophysical Journal Supplement, online catalog available at http://www.astronomy.ohio-state.edu/Spitzer2015

    Mitochondrial targeting of cyclosporin A enables selective inhibition of cyclophilin-D and enhanced cytoprotection after glucose and oxygen deprivation

    Get PDF
    CsA (cyclosporin A) is a hydrophobic undecapeptide that inhibits CyPs (cyclophilins), a family of PPIases (peptidylprolyl cis–trans isomerases). In some experimental models, CsA offers partial protection against lethal cell injury brought about by transient ischaemia; this is believed to reflect inhibition of CyP-D, a mitochondrial isoform that facilitates formation of the permeability transition pore in the mitochondrial inner membrane. To evaluate this further, we have targeted CsA to mitochondria so that it becomes selective for CyP-D in cells. This was achieved by conjugating the inhibitor to the lipophilic triphenylphosphonium cation, enabling its accumulation in mitochondria due to the inner membrane potential. In a cell-free system and in B50 neuroblastoma cells the novel reagent (but not CsA itself) preferentially inhibited CyP-D over extramitochondrial CyP-A. In hippocampal neurons, mitochondrial targeting markedly enhanced the capacity of CsA to prevent cell necrosis brought about by oxygen and glucose deprivation, but largely abolished its capacity to inhibit glutamate-induced cell death. It is concluded that CyP-D has a major pathogenic role in ‘energy failure’, but not in glutamate excitotoxicity, where cytoprotection primarily reflects CsA interaction with extramitochondrial CyPs and calcineurin. Moreover, the therapeutic potential of CsA against ischaemia/reperfusion injuries not involving glutamate may be improved by mitochondrial targeting
    corecore