14 research outputs found
Universiti tempatan perlu terus diperkasa
AMANAT Tahun Baru 2012 Menteri Pengajian Tinggi,
Datuk Seri Mohamed Khaled Nordin pada 26 Januari lalu dengan slogan 'Berfikiran global bertindak lokal' adalah suatu 'tour
de force' yang melakarkan wawasan beliau untuk mencetuskan anjakan paradigma dalam arena pengajian tinggi semasa
Professors, share your views for a better world
THE newly formed National Professors Council (MPN) will, at its first congress on July 6- and 7, reaffirm its commitment to building a knowledge-based society and support the 1Malaysia concept, the New Economic Model, Government Transformation Plan and Economic Transformation Plan
Upregulation of interleukin-19 in severe asthma: a potential saliva biomarker for asthma severity
Interleukin (IL)-19, a designated IL-20 subfamily cytokine, has been implicated in inflammatory disorders including rheumatoid arthritis, psoriasis and, lately, asthma. Here, through the analysis of transcriptomic datasets of lung tissue of large asthma cohorts, we report that IL-19 expression is upregulated in asthma and correlates with disease severity. The gene expression of IL-19 was significantly higher in lung tissue from patients with severe and mild/moderate asthma compared to healthy controls. IL-19 protein level, however, was significantly higher in the blood and saliva of patients with severe asthma compared to mild/ moderate subgroups as measured by ELISA assay. IL-19 protein level was not affected by corticosteroid treatment in plasma. Our data provide insights into the potential use of IL-19 as a saliva marker for asthma severity and a potential therapeutic target
The IPBES Conceptual Framework - connecting nature and people
The first public product of the Intergovernmental Platform on Biodiversity and Ecosystem Services (IPBES) is its Conceptual Framework. This conceptual and analytical tool, presented here in detail, will underpin all IPBES functions and provide structure and comparability to the syntheses that IPBES will produce at different spatial scales, on different themes, and in different regions. Salient innovative aspects of the IPBES Conceptual Framework are its transparent and participatory construction process and its explicit consideration of diverse scientific disciplines, stakeholders, and knowledge systems, including indigenous and local knowledge. Because the focus on co-construction of integrative knowledge is shared by an increasing number of initiatives worldwide, this framework should be useful beyond IPBES, for the wider research and knowledge-policy communities working on the links between nature and people, such as natural, social and engineering scientists, policy-makers at different levels, and decision-makers in different sectors of society