Conception d'un système de commande autonome pour le simulateur matériel de satellite LABSAT

Dans un contexte comme celui des technologies aérospatiales, qui se caractérise non seulement par sa complexité, mais aussi par sa difficulté à régler les erreurs une fois que le véhicule est dans son environnement final, l’utilisation des simulateurs de satellite sur Terre pour le développement et la vérification de nouveaux systèmes offre une alternative intéressante aux simulations traditionnelles par ordinateur. Plus précisément, dans le cas de la commande d’attitude, la possibilité d’utiliser la dynamique réelle du satellite pendant les phases de conception et de développement présente des avantages tels que l’inclusion des systèmes difficiles à modéliser et la réduction du risque d’erreur et du temps de vérification. Cependant, cette technologie est encore récente et est de ce fait sujette à être améliorée afin d’offrir le meilleur scénario possible pour le développement des algorithmes de commande d’attitude de la prochaine génération de satellites. À cet effet, l’Université de Sherbrooke et la société NGC Aérospatiale Ltée. développent en partenariat le simulateur matériel de satellite LABSAT qui possède toutes les fonctionnalités d’un véhicule spatial incluant les actionneurs, capteurs, calculateurs embarqués et éléments flexibles. Le projet présenté dans ce document consiste à concevoir et mettre en œuvre sur le minisatellite LABSAT un premier système de navigation et commande permettant d’exécuter les manœuvres en orientation à partir d’une station de contrôle. À cette fin, les différents sous-systèmes du simulateur matériel ont été intégrés et des solutions en termes de calibration de capteurs, d’estimateur d’état et de systèmes de commande ont été analysées théoriquement et en simulation. Les techniques les plus appropriées ont été, par la suite, implémentées et évaluées sur le système final, dans le but de vérifier leur fonctionnement dans l’environnement réel

The adaptive optics lucky imager (AOLI): presentation, commissioning, and AIV innovations

Here we present the Adaptive Optics Lucky Imager (AOLI), a state-of-the-art instrument which makes use of two well proved techniques, Lucky Imaging (LI) and Adaptive Optics (AO), to deliver diffraction limited imaging at visible wavelengths, 20 mas, from ground-based telescopes. Thanks to its revolutionary TP3-WFS, AOLI shall have the capability of using faint reference stars. In the extremely-big telescopes era, the combination of techniques and the development of new WFS systems seems the clue key for success. We give details of the integration and verification phases explaining the defiance that we have faced and the innovative and versatile solutions for each of its subsystems that we have developed, providing also very fresh results after its first fully-working observing run at the William Herschel Telescope (WHT).Comment: 6 pages, 6 figures, conference. arXiv admin note: text overlap with arXiv:1703.09354, arXiv:1608.0480

Educación al cuidador informal del paciente oncológico paliativo en el domicilio: Programa de Salud de Enfermería en Atención Primaria

Introducción: Los cuidados paliativos se basan en una atención integral de los pacientes diagnosticados de enfermedades terminales, como el cáncer y sus familias, manteniendo su autonomía y dignidad hasta el final de la vida. Se considera el domicilio como el lugar más apropiado y de principal elección para la atención y fallecimiento de los pacientes paliativos. La educación temprana al cuidador principal asegurará una mejora de la calidad de vida y bienestar del paciente oncológico terminal a través del control de síntomas y soporte emocional del núcleo familiar. Objetivo: Elaborar un Programa de Educación Para la Salud de atención domiciliaria dirigido al cuidador informal de pacientes oncológicos paliativos. Metodología: Se ha realizado una búsqueda bibliográfica en las diferentes bases de datos científicas, principalmente desde 2014, siendo complementada con guías clínicas y páginas de interés. Así como, el contacto con asociaciones del paciente paliativo para la elaboración del programa de educación de cuidados domiciliarios por parte del equipo de atención primaria. Desarrollo: El programa se divide en cuatro sesiones dirigidas al cuidador informal del paciente oncológico paliativo. Durante estas se instruirá e informará sobre los cuidados paliativos domiciliarios básicos, manejo y administración de fármacos por vía subcutánea e intervención psicológica en el acompañamiento al final de la vida. Conclusiones: La educación e información por parte del personal de enfermería de atención primaria resulta imprescindible en la adquisición y mejora de los cuidados paliativos domiciliarios. Una intervención integral del familiar mejorará la calidad de vida y bienestar del paciente hasta el fallecimiento. Al igual que será esencial para el cuidador principal, destacando el soporte emocional y manejo del duelo anticipado. <br /

Pembentukan Karakter Pada Anak-Anak Panti Asuhan Yayasan Tunas Kasih Olayama Raya Melalui Nyanyian Rohani

Membangun karakter bangsa dimulai dari kecintaan terhadap anak-anak. Bangsa yang besar dilihat dari berbagai sudut pandang yang salah satunya adalah kebahagiaan anak-anak. Anak-anak bangsa harus dididik dengan karakter yang baik sejak usia dini melalui kegiatan-kegiatan positif. Kegiatan sosial ini menanamkan karakter positif bagi anak-anak bangsa yang ada di panti asuhan tunas kasih olayama raya. Tujuanya agar anak-anak panti asuhan dapat merasakan uluran kasih dan perhatian dari masyarakat luar. Observasi langsung kelapangan dan berdiskusi dengan pengurus panti memberikan gambaran terhadap permasalahan yang dihadapi sehingga tim dapat mencari solusi yang tepat. Kegiatan ini telah memberikan dampak positif kepada semua pihak terutama anak-anak panti. Mereka semakin bersemangat, termotivasi dengan kehadiran tim di tengah-tengah mereka

Characterization of begomoviruses sampled during severe epidemics in tomato cultivars carrying the Ty-1 gene

Tomato yellow leaf curl virus (TYLCV, genus Begomovirus, family Geminiviridae) is a major species that causes a tomato disease for which resistant tomato hybrids (mainly carriers of the Ty-1/Ty-3 gene) are being used widely. We have characterized begomoviruses severely affecting resistant tomato crops in Southeast Spain. Circular DNA was prepared from samples by rolling circle amplification, and sequenced by massive sequencing (2015) or cloning and Sanger sequencing (2016). Thus, 23 complete sequences were determined, all belonging to the TYLCV Israel strain (TYLCV-IL). Massive sequencing also revealed the absence of other geminiviral and beta-satellite sequences. A phylogenetic analysis showed that the Spanish isolates belonged to two groups, one related to early TYLCV-IL isolates in the area (Group 1), and another (Group 2) closely related to El Jadida (Morocco) isolates, suggesting a recent introduction. The most parsimonious evolutionary scenario suggested that the TYLCV isolates of Group 2 are back recombinant isolates derived from TYLCV-IS76, a recombinant virus currently predominating in Moroccan epidemics. Thus, an infectious Group 2 clone (TYLCV-Mu15) was constructed and used in in planta competition assays against TYLCV-IS76. TYLCV-Mu15 predominated in single infections, whereas TYLCV-IS76 did so in mixed infections, providing credibility to a scenario of co-occurrence of both types of isolates

Septins localize to microtubules during nutritional limitation in Saccharomyces cerevisiae

<p>Abstract</p> <p>Background</p> <p>In <it>Saccharomyces cerevisiae</it>, nutrient limitation stimulates diploid cells to undergo DNA replication and meiosis, followed by the formation of four haploid spores. Septins are a family of proteins that assemble a ring structure at the mother-daughter neck during vegetative growth, where they control cytokinesis. In sporulating cells, the septin ring disassembles and septins relocalize to the prospore membrane.</p> <p>Results</p> <p>Here, we demonstrate that nutrient limitation triggers a change in the localization of at least two vegetative septins (Cdc10 and Cdc11) from the bud neck to the microtubules. The association of Cdc10 and Cdc11 with microtubules persists into meiosis, and they are found associated with the meiotic spindle until the end of meiosis II. In addition, the meiosis-specific septin Spr28 displays similar behavior, suggesting that this is a common feature of septins. Septin association to microtubules is a consequence of the nutrient limitation signal, since it is also observed when haploid cells are incubated in sporulation medium and when haploid or diploid cells are grown in medium containing non-fermentable carbon sources. Moreover, during meiosis II, when the nascent prospore membrane is formed, septins moved from the microtubules to this membrane. Proper organization of the septins on the membrane requires the sporulation-specific septins Spr3 and Spr28.</p> <p>Conclusion</p> <p>Nutrient limitation in <it>S. cerevisiae </it>triggers the sporulation process, but it also induces the disassembly of the septin bud neck ring and relocalization of the septin subunits to the nucleus. Septins remain associated with microtubules during the meiotic divisions and later, during spore morphogenesis, they are detected associated to the nascent prospore membranes surrounding each nuclear lobe. Septin association to microtubules also occurs during growth in non-fermentable carbon sources.</p

The Farallon-Aluk ridge collision with South America: Implications for the geochemical changes of slab window magmas from fore- to back-arc

The collision of a divergent ocean ridge may evolve into two end cases: in the continuity of ocean-floor subduction, or in the detachment of the subducted plate. The northern Patagonia active plate margin has the unique situation that in Cenozoic time it has been subjected to two divergent ridge collisions, each one representing one of the end members. The Neogene Antarctica-Nazca divergent ridge collision evolved as a continuous ocean-floor subduction system, promoting a magmatic hiatus at the arc axis, the obduction of part of the ridge ocean-floor in the fore-arc, and basaltic volcanism in the back-arc. In contrast, the Paleogene Farallon-Aluk divergent ridge collision evolved into a transform margin, with the detachment and sinking of the Aluk plate and the development of a large slab window. As in the previous case, this collision promoted a magmatic hiatus at the arc axis, but the tectono-magmatic scenario changed to postorogenic synextensional volcanism that spread to the former fore-arc (basalt, andesite, rhyolite) and former back-arc (bimodal ignimbrite flare-up, basalt). Geochemistry of this slab window synextensional volcanism shows more MORB-like basalts towards the former fore-arc, and MORB-OIB-like basalts towards the former back-arc. Instead, an isolated undeformable crustal block in the former back-arc, with an "epeirogenic" response to the slab window and extensional regime, was covered by OIB-type basalts after uplift. Major elements show that slab window basalts reach TiO2 values up to 3 wt%, as compared with the top value of 1.5 wt% of arc magmas. Besides, the MgO with respect to (FeOt + Al2O3) ratio helps to distinguish slab window magma changes from the former fore-arc to the former back-arc and also with respect to the "epeirogenic" block. Higher contents of HFS elements such as Nb and Ta also help to distinguish this slab window from arc magmas and also, to distinguish slab window magma changes from the former fore-arc to the former back-arc and "epeirogenic" block settings. The isotope compositions of slab window magmatism show a disparate coeval array from MORB to crustal sources, interpreted as a consequence of the lack of protracted storage and homogenization due to the extensional setting.Facultad de Ciencias Naturales y Muse

Complete proteome of a quinolone-resistant Salmonella Typhimurium phage type DT104B clinical strain

Salmonellosis is one of the most common and widely distributed foodborne diseases. The emergence of Salmonella strains that are resistant to a variety of antimicrobials is a serious global public health concern. Salmonella enterica serovar Typhimurium definitive phage type 104 (DT104) is one of these emerging epidemic multidrug resistant strains. Here we collate information from the diverse and comprehensive range of experiments on Salmonella proteomes that have been published. We then present a new study of the proteome of the quinolone-resistant Se20 strain (phage type DT104B), recovered after ciprofloxacin treatment and compared it to the proteome of reference strain SL1344. A total of 186 and 219 protein spots were recovered from Se20 and SL1344 protein extracts, respectively, after two-dimensional gel electrophoresis. The signatures of 94% of the protein spots were successfully identified through matrix-assisted laser desorption/ionization mass spectrometry (MALDI-TOF MS). Three antimicrobial resistance related proteins, whose genes were previously detected by polymerase chain reaction (PCR), were identified in the clinical strain. The presence of these proteins, dihydropteroate synthase type-2 (sul2 gene), aminoglycoside resistance protein A (strA gene) and aminoglycoside 6'-N-acetyltransferase type Ib-cr4 (aac(6')-Ib-cr4 gene), was confirmed in the DT104B clinical strain. The aac(6')-Ib-cr4 gene is responsible for plasmid-mediated aminoglycoside and quinolone resistance. This is a preliminary analysis of the proteome of these two S. Typhimurium strains and further work is being developed to better understand how antimicrobial resistance is developing in this pathogen

Stable and Broad Spectrum Cross-Protection Against Pepino Mosaic Virus Attained by Mixed Infection

While recent pepino mosaic virus (PepMV; species Pepino mosaic virus, genus Potexvirus, family Alphaflexiviridae) epidemics seem to be predominantly caused by isolates of the CH2 strain, PepMV epidemics in intensive tomato crops in Spain are caused by both CH2 and EU isolates that co-circulate, representing a challenge in terms of control, including cross-protection. In this work, we hypothesized that mixed infections with two mild isolates of the EU and CH2 strains (PepMV-Sp13 and -PS5, respectively) may be useful in PepMV cross-protection in Spanish epidemics, providing protection against a broad range of aggressive isolates. Thus, we performed a range of field trials and an experimental evolution assay to determine the phenotypic and genetic stability of PepMV-Sp13 and -PS5 mixed infections, as well as their cross-protective efficiency. Our results showed that: (i) the phenotype of PepMV-Sp13 and -PS5 mixed infections was mild and did not change significantly when infecting different tomato cultivars or under different environmental conditions in Spain, (ii) PepMV-Sp13 and -PS5 mixed infections provided more efficient protection against two aggressive EU and CH2 isolates than single infections, and (iii) PepMV-Sp13 and -PS5, either in single or in mixed infections, were less variable than other two PepMV isolates occurring naturally in PepMV epidemics in Spain