64 research outputs found
Expression of SDF-1α and nuclear CXCR4 predicts lymph node metastasis in colorectal cancer
- Author
- A Sekikawa
- A Sekikawa
- AG Kayali
- AZ Fernandis
- B Haribabu
- BJ Rollins
- C Murdoch
- H Fukui
- H Fukui
- H Hiraishi
- H Kawamata
- H Shim
- H Yamagishi
- IS Zeelenberg
- J Imura
- J Pouysségur
- JP Spano
- K Ichikawa
- K Shibuta
- K Shibuta
- K Tachibana
- K Tashiro
- M Baggiolini
- M Burger
- M Hoshino
- M Kato
- MJ Orsini
- MK Wendt
- N Wang
- N Yoshitake
- S Brand
- S Fujii
- S Tomita
- SF Soriano
- SR Vlahakis
- T Fujimori
- TN Hartmann
- YR Zou
- ZJ Cheng
- Publication venue
- Nature Publishing Group
- Publication date
- Field of study
Although stromal cell-derived factor (SDF)-1α and its receptor CXCR4 are experimentally suggested to be involved in tumorigenicity, the clinicopathological significance of their expression in human disease is not fully understood. We examined SDF-1α and CXCR4 expression in colorectal cancers (CRCs) and their related lymph nodes (LNs), and investigated its relationship to clinicopathological features. Specimens of 60 primary CRCs and 27 related LNs were examined immunohistochemically for not only positivity but also immunostaining patterns for SDF-1α and CXCR4. The relationships between clinicopathological features and SDF-1α or CXCR4 expression were then analysed. Stromal cell-derived factor-1α and CXCR4 expression were significantly associated with LN metastasis, tumour stage, and survival of CRC patients. Twenty-nine of 47 CXCR4-positive CRCs (61.7%) showed clear CXCR4 immunoreactivity in the nucleus and a weak signal in the cytoplasm (nuclear type), whereas others showed no nuclear immunoreactivity but a diffuse signal in the cytoplasm and at the plasma membrane (cytomembrane type). Colorectal cancer patients with nuclear CXCR4 expression showed significantly more frequent LN metastasis than did those with cytomembrane expression. Colorectal cancer patients with nuclear CXCR4 expression in the primary lesion frequently had cytomembrane CXCR4-positive tumours in their LNs. In conclusion, expression of SDF-1α and nuclear CXCR4 predicts LN metastasis in CRCs
Transposable-Element Associated Small RNAs in Bombyx mori Genome
- Author
- A Vermeulen
- AA Aravin
- AG Clark
- AJ Enright
- B Czech
- C Li
- Caixia Yu
- CD Malone
- DJ Hedges
- HGS Consortium
- I. King Jordan
- J Brennecke
- J Piriyapongsa
- J Piriyapongsa
- JE Park
- JS Khurana
- JS Yang
- Jun Yu
- K Jazdzewski
- K Okamura
- K Saito
- KM Nishida
- M Ghildiyal
- M Osanai-Futahashi
- M Zuker
- N Robine
- NC Lau
- NC Lau
- NC Lau
- NR Smalheiser
- OH Tam
- PD Zamore
- PL Deininger
- Qing Zhou
- R Li
- RA Holt
- S Chambeyron
- S Kawaoka
- S Kawaoka
- S Kawaoka
- S Kawaoka
- S Kawaoka
- S Lehnert
- S Richards
- Songnian Hu
- T Watanabe
- TISG Consortium
- TW Nilsen
- V Nene
- WJ Chung
- X Wang
- X Yu
- Xiaomin Yu
- Xumin Wang
- Y Cai
- Y Kawamura
- Yimei Cai
- YR Fujii
- Publication venue
- Public Library of Science
- Publication date
- 08/05/2012
- Field of study
Small RNAs are a group of regulatory RNA molecules that control gene expression at transcriptional or post-transcriptional levels among eukaryotes. The silkworm, Bombyx mori L., genome harbors abundant repetitive sequences derived from families of retrotransposons and transposons, which together constitute almost half of the genome space and provide ample resource for biogenesis of the three major small RNA families. We systematically discovered transposable-element (TE)-associated small RNAs in B. mori genome based on a deep RNA-sequencing strategy and the effort yielded 182, 788 and 4,990 TE-associated small RNAs in the miRNA, siRNA and piRNA species, respectively. Our analysis suggested that the three small RNA species preferentially associate with different TEs to create sequence and functional diversity, and we also show evidence that a Bombyx non-LTR retrotransposon, bm1645, alone contributes to the generation of TE-associated small RNAs in a very significant way. The fact that bm1645-associated small RNAs partially overlap with each other implies a possibility that this element may be modulated by different mechanisms to generate different products with diverse functions. Taken together, these discoveries expand the small RNA pool in B. mori genome and lead to new knowledge on the diversity and functional significance of TE-associated small RNAs
Inhibition of autophagy, lysosome and VCP function impairs stress granule assembly
- Author
- A Kuma
- A Poletti
- B Bukau
- B Ossareh-Nazari
- BK Saha
- C Boyault
- C Dargemont
- C Kraft
- CJ Rodriguez-Ortiz
- D Amore
- D C Rubinsztein
- D Seigneurin-Berny
- DJ Klionsky
- F F Morelli
- GD Watts
- H Meyer
- H Richly
- H Tourriere
- HJ Kim
- HL Zhou
- J Liu
- J Vinet
- JO Johnson
- JR Buchan
- JS Ju
- JS Ju
- JS Ju
- K Fujii
- K Moreau
- K Thedieck
- LC Reineke
- M Takahashi
- ME Lindquist
- N Gilks
- N Hosokawa
- N Kedersha
- NG Farny
- P Anderson
- P Anderson
- Q Defenouillere
- Q Ding
- R Mazroui
- R Verma
- RC Piper
- S Carra
- S De Biasi
- S J Seguin
- S Kwon
- SR Kimball
- T Jacobson
- T Ohn
- TF Chou
- TH Clausen
- U Schubert
- V Athanasopoulos
- V Cherkasov
- V Kirkin
- VI Korolchuk
- WJ Kim
- Y Kabeya
- Y Kawaguchi
- Y Nishida
- YE Kim
- YR Li
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2014
- Field of study
Stress granules (SGs) are mRNA-protein aggregates induced during stress, which accumulate in many neurodegenerative diseases. Previously, the autophagy-lysosome pathway and valosin-containing protein (VCP), key players of the protein quality control (PQC), were shown to regulate SG degradation. This is consistent with the idea that PQC may survey and/or assist SG dynamics. However, despite these observations, it is currently unknown whether the PQC actively participates in SG assembly. Here, we describe that inhibition of autophagy, lysosomes and VCP causes defective SG formation after induction. Silencing the VCP co-factors UFD1L and PLAA, which degrade defective ribosomal products (DRIPs) and 60S ribosomes, also impaired SG assembly. Intriguingly, DRIPs and 60S, which are released from disassembling polysomes and are normally excluded from SGs, were significantly retained within SGs in cells with impaired autophagy, lysosome or VCP function. Our results suggest that deregulated autophagy, lysosomal or VCP activities, which occur in several neurodegenerative (VCP-associated) diseases, may alter SG morphology and composition
Alopecia in a Viable Phospholipase C Delta 1 and Phospholipase C Delta 3 Double Mutant
- Author
- A Akutagawa
- A Awgulewitsch
- AC Resnick
- AM Seeds
- AM Seeds
- Amanda Ewart Toland
- AR Godwin
- AR Godwin
- AV Tkatchenko
- B Ananthanarayanan
- Birgit Blanck
- C Hasdemir
- C Newton-Cheh
- C Stocking
- CG Nebigil
- CM Godin
- CS Potter
- CS Potter
- D Concepcion
- DW Leung
- E Festa
- F Martin-Belmonte
- F Runkel
- Fabian Runkel
- FG Lin
- G Di Paolo
- H Kulessa
- H Yagisawa
- H Yagisawa
- H Yagisawa
- H Yagisawa
- HF Paterson
- IA Maksakova
- J Frank
- JA Nowak
- JD Stallings
- JD York
- Jean-Louis Guénet
- JP Monserrate
- JP Sundberg
- K Fukami
- K Fukami
- K Fukami
- K Fukami
- K Nomoto
- KA Kaproth-Joslin
- Kiyoko Fukami
- KS Stenn
- L Karlsson
- L Langbein
- L Ma
- L Mecklenburg
- L Mecklenburg
- L Mecklenburg
- LF Jave-Suarez
- LF Jave-Suarez
- M Fujii
- M Hirata
- M Hirata
- M Ichinohe
- M Magerl
- M Nakamura
- M Okada
- M Rebecchi
- M Rendl
- MA Rogers
- MA Rogers
- Maik Hintze
- Marion Michels
- MJ Berridge
- MM Tsui
- MR Schneider
- N Liu
- N Wilson
- ND Pruett
- P Garcia
- P Jern
- P Varnai
- PG Suh
- R Paus
- RL Peterson
- RS Sidhu
- S Ishikawa
- S Muller-Rover
- S Shimohama
- SA Danielsen
- Sebastian Griesing
- SG Rhee
- T Pawelczyk
- T Takabatake
- T Xiang
- Thomas Franz
- TK Harden
- VA Botchkarev
- VA Botchkarev
- XT Hu
- Y Irino
- Y Naito
- Y Nakamura
- Y Nakamura
- Y Nakamura
- Y Nakamura
- Y Shimomura
- Y Tomita
- YC Lien
- YR Qin
- Z Kouchi
- Publication venue
- Public Library of Science
- Publication date
- 19/06/2012
- Field of study
BACKGROUND: Inositol 1,4,5trisphosphate (IP(3)) and diacylglycerol (DAG) are important intracellular signalling molecules in various tissues. They are generated by the phospholipase C family of enzymes, of which phospholipase C delta (PLCD) forms one class. Studies with functional inactivation of Plcd isozyme encoding genes in mice have revealed that loss of both Plcd1 and Plcd3 causes early embryonic death. Inactivation of Plcd1 alone causes loss of hair (alopecia), whereas inactivation of Plcd3 alone has no apparent phenotypic effect. To investigate a possible synergy of Plcd1 and Plcd3 in postnatal mice, novel mutations of these genes compatible with life after birth need to be found. METHODOLOGY/PRINCIPAL FINDINGS: We characterise a novel mouse mutant with a spontaneously arisen mutation in Plcd3 (Plcd3(mNab)) that resulted from the insertion of an intracisternal A particle (IAP) into intron 2 of the Plcd3 gene. This mutation leads to the predominant expression of a truncated PLCD3 protein lacking the N-terminal PH domain. C3H mice that carry one or two mutant Plcd3(mNab) alleles are phenotypically normal. However, the presence of one Plcd3(mNab) allele exacerbates the alopecia caused by the loss of functional Plcd1 in Del(9)olt1Pas mutant mice with respect to the number of hair follicles affected and the body region involved. Mice double homozygous for both the Del(9)olt1Pas and the Plcd3(mNab) mutations survive for several weeks and exhibit total alopecia associated with fragile hair shafts showing altered expression of some structural genes and shortened phases of proliferation in hair follicle matrix cells. CONCLUSIONS/SIGNIFICANCE: The Plcd3(mNab) mutation is a novel hypomorphic mutation of Plcd3. Our investigations suggest that Plcd1 and Plcd3 have synergistic effects on the murine hair follicle in specific regions of the body surface
Structure, function, and evolution of plant NIMA-related kinases: implication for phosphorylation-dependent microtubule regulation
- Author
- A Bichet
- A Fourest-Lieuvin
- A Grallert
- A Kawabe
- A Kirik
- A Suttangkakul
- A Walia
- AJ Wright
- AM Fry
- AR Hardham
- AR Paredez
- AT Whittington
- B Liu
- B Zhang
- BA Bradley
- BR Mardin
- C Ambrose
- C Ambrose
- C Belham
- C Camilleri
- C Wang
- CM Ho
- CT Zeng
- D Burk
- D Demidov
- D Demidov
- D Kurihara
- D Kurihara
- D Lin
- D Twell
- D Wloga
- E Kawamura
- E Kawamura
- EAA Silva Da
- EM Gifford
- F Agueci
- F Berger
- F Kumagai
- F Vigneault
- G Ben-Nissan
- G Manning
- G Strompen
- G Yang
- GM Yoon
- GO Wasteneys
- GO Wasteneys
- H Motose
- H Motose
- H Motose
- H Nakagami
- H Shibaoka
- Hiroyasu Motose
- J Azimzadeh
- J Rapley
- J Roig
- J Traas
- J Vogel
- JC Ambrose
- JC Sedbrook
- JD Parker
- JJ Hartman
- JJ Lindeboom
- JM Keck
- JM Kollman
- JW Hammond
- K Hori
- K Ishida
- K Kosetsu
- K Naoi
- K Noguchi
- K Noguchi
- K Sugimoto
- K Taoka
- Kento Otani
- KJ Verhey
- L Kohoutová
- L Lei
- L O’Regan
- L Pnueli
- L Spinner
- LM Quarmby
- M Abe
- M Alvarado-Kristensson
- M Barisic
- M Beck
- M Bringmann
- M Cloutier
- M Fujita
- M Fujita
- M Melixetian
- M Mihara
- M Moritz
- M Nakamura
- M Nakamura
- M Nakamura
- M Nakamura
- M Notaguchi
- M Notaguchi
- M Pastuglia
- M Sakiyama
- M Sakiyama-Sogo
- M Sasabe
- M Sasabe
- M Sasabe
- M Sassi
- M Shimamura
- M Sirajuddin
- M Uyttewaal
- M Webb
- MA Jones
- Mai Kanazawa
- MC Ledbetter
- MG Heisler
- MJ O’Connell
- MR Mahjoub
- MT Bertran
- MW Richards
- N Mizushima
- N Sugiyama
- O Hamant
- P Binarová
- P Kumar
- P Nick
- P Rellos
- PB Green
- PJ Sammark
- R Loughlin
- R Nishihama
- R Nishihama
- RA Torres-Ruiz
- RC Eng
- RS Hames
- RS Hames
- S Drevensek
- S Fujii
- S Fujita
- S Ikeno
- S Kim
- S Sdelci
- S Takatani
- S Thitamadee
- S Wang
- S Westermann
- SA Oh
- SA Oh
- SA Osmani
- SA Osmani
- Shogo Takatani
- SJ Lee
- SL Shaw
- SR Cutler
- T Abe
- T Abe
- T Bouquin
- T Hamada
- T Hamada
- T Horio
- T Hotta
- T Ishida
- T Ishida
- T Krupnova
- T Mitchison
- T Murata
- T Murata
- T Murata
- T Sakai
- T Shoji
- T Soyano
- Taku Takahashi
- TC Lin
- TI Baskin
- TI Baskin
- V Kirik
- Wehenkel and Janke
- Y Ban
- Y Blume
- Y Fu
- Y Fu
- Y Kobayashi
- Y Ning
- Y Oda
- Y Oda
- Y Oda
- Y Takahashi
- YR Lee
- Z Kong
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy
- Author
- Aahlin EK
- Aamer A
- Aaniana K
- Ababneh A
- Abaliksta T
- Abantanga F
- Abantanga F
- Abbas A
- Abbas M
- Abbasy J
- Abbo O
- Abbo O
- Abbott T
- Abbouch M
- Abd El Galeel A
- Abd El Hameed OS
- Abd El Hamid N
- Abd El Salam Y
- Abd El Slam M
- Abd El-Salam F
- Abd Elrasoul Y
- Abd-Elmawla M
- Abd-Elrasoul Y
- Abdallah E
- Abdallah E
- Abdel-Aty A
- Abdel-Hameed N
- Abdel-Kader SM
- Abdel-Wahab NYE
- Abdelaal A
- Abdelaty M
- Abdelazeam AR
- Abdelazim G
- Abdelaziz MA
- Abdelbadeai K
- Abdelfatah A
- AbdelFattah I
- Abdelgelil A
- Abdelghany S
- Abdelhady S
- Abdelhamed R
- Abdelhamid A
- Abdelhaq A
- Abdelkader M
- Abdelkader M
- Abdelkader O
- Abdelkareem A
- Abdelkhalek M
- Abdelmageed E
- Abdelmotaleb I
- Abdelraheim M
- Abdelraouf AM
- Abdelrouf DM
- Abdelshafy M
- Abdelshakour M
- Abdrabou AK
- Abdul-Latif S
- Abdulaziz H
- Abdulaziz M
- Abdulbagi O
- Abdulgawad M
- Abdulhakeem EM
- Abdullah AAN
- Abdullah MA
- Abdullah N
- Abdullah NAN
- Abdullah NAN
- Abdullahi L
- Abdurrazzaaq A
- Abebe NS
- Abebe NS
- Abem OE
- Aber A
- Abington E
- Abiola O
- Aboarab A
- Aboelella M
- Aboelmagd O
- Aboelsoud MR
- Aboraya M
- Aboraya M
- Abouelnasr A
- Aboul-Naga MS
- Abouzahra A
- Abouzaid A
- Abozaid M
- Abozeid K
- Abozyed MAF
- Abu Qumbos A
- Abu-toyour M
- Abubakr M
- Abudeeb H
- Abuowda Y
- Abuqwaider E
- Abusalem L
- Abuseif M
- Abushamleh S
- Acharya P
- Ackom E
- Acquah E
- Adam A
- Adam N
- Adams R
- Adamu A
- Adawi I
- Adawi M
- Adebanjo A
- Adebanjo A
- Adebola O
- Adedeji A
- Adekoya A
- Adel A
- Adel A
- Adel BE
- Adel I
- Adella FJ
- Adelshone A
- Ademuyiwa A
- Ademuyiwa A
- Ademuyiwa AO
- Ademuyiwa AO
- Ademuyiwa AO
- Ademuyiwa AO
- Adenekan B
- Adeniran J
- Adeniran J
- Adeniyi A
- Adeniyi A
- Adesanya O
- Adesanya O
- Adesina A
- Adesina A
- Adesuyi A
- Adeyeye A
- Adeyeye A
- Adeyeye A
- Adham W
- Adhitama N
- Adil M
- Adisa AO
- Adisa AO
- Adu-Aryee N
- Afana S
- Afandy A
- Afifi AM
- Afzal M
- Agalianos C
- Agalianos C
- Agarwal A
- Agarwal A
- Agarwal A
- Agbedinu K
- Agius M
- Aglan A
- Aguado Suarez N
- Aguilar-Jimenez J
- Aguilera M
- Aguilera ML
- Aguilera ML
- Aguilera ML
- Aguilera O
- Aguilera-Arevalo M-L
- Ahlonsou G
- Ahlqvist S
- Ahlqvist S
- Ahlqvist S
- Ahmed A
- Ahmed A
- Ahmed A
- Ahmed EA
- Ahmed H
- Ahmed H
- Ahmed H
- Ahmed LAM
- Ahmed S
- Ahmed S
- Ahmed SM
- Ahounou EYS
- Aigrain Y
- Aiyaman C
- Ajah J
- Ajai O
- Ajao A
- Ajao AE
- Ajiboye A
- Akatibo E
- Akeel N
- Akhtar M
- Akoto E
- Akpenyi O
- Al Amin S
- Al Attar SM
- Al Awwad S
- Al Barrawi FE
- Al Bastawis F
- Al Meligy A
- Al Rafati AAR
- Al Raouf EA
- Al Saied G
- Al Subaie N
- Al-Aarag AA-R
- Al-Azraqi IAA
- Al-Bahrani A
- Al-Buhaisi A
- Al-Dakka E
- Al-Faifi JJ
- Al-faqawi M
- Al-farram H
- Al-Hameedi HII
- Al-Hasani RKMJ
- Al-khatib A
- Al-Mallah A
- Al-Marakby D
- Al-Mousa M
- Al-Nahrawi S
- Al-Obaedi O
- Al-saqqa S
- Al-Saqqa SW
- Al-Saqqa SW
- Al-shammari A
- Al-Slaibi I
- Al-taher T
- Alaael-Dein S
- Alada M
- Alahmady O
- Alakaloko F
- Alakaloko F
- Alaloul E
- Alamin S
- Alamoudi M
- Alamoudi U
- Albeladi B
- Albiety A
- Alcca Ticona W
- Aldalaq A
- Aldhafeeri S
- Aledrisy M
- Alejos Bermudez YE
- Alexander P
- Alexander P
- Alexander P
- Alexandre C
- Alfarsi MA
- Alghamdi A
- Alghamdi B
- Alghamdi M
- Alghamdi MSA
- Algohary O
- Alhabli I
- Alhady K
- Alhammali T
- Alhassan B
- Alhazmi W
- Alhendy M
- Alherz M
- Ali A
- Ali A
- Ali A
- Ali CDM
- Ali E
- Ali FM
- Ali H
- Ali S
- Ali SAWEW
- Ali SS
- Ali THA
- Ali W
- Alihonou T
- Alimi Q
- Alis H
- Aliyu H
- Aliyu M
- Aliyu S
- Aljboor K
- Aljiffry M
- Aljiffry M
- Aljohani E
- Aljohani E
- Aljohani S
- Alkaaki A
- Alkammash A
- Alkelani M
- Alkhabbaz D
- Alkhouri M
- Allam M
- Allam M
- Allam Y
- Allegri A
- Allegri A
- Allen JLY
- Allott R
- Almallah A
- Almoflihi A
- Almuallem S
- Almy J
- Alnaby MH
- Alnawam E
- Alnuqaydan SA
- Alnusairat A
- Alomar IN
- Alqahtani E
- Alqahtani S
- Alrahawy M
- Alrajraji M
- Alrifaie A
- AlRowais M
- Alsaggaf M
- Alsaggaf MU
- Alsaggaf MU
- Alser OH
- Alshareef R
- Altaf A
- Altaf A
- Altamimi A
- Altamimi A
- Altamimi A
- Altamimi A
- Altamini A
- Altarayra M
- Althwainy A
- Altibi A
- Altinel Y
- Altinel Y
- Altoe F
- Altwigry AM
- Altwijri A
- Alvarado Jaramillo R
- Alvarez Barreda LM
- Alvi AR
- Alwafai MG
- Aly AK
- Aly MYM
- Alyacoubi S
- Alyahya R
- Alyami R
- Alyami R
- AlYoussef I
- Alzahrani A
- Alzahrani M
- Alzahrani M
- Alzayat T
- Aman NF
- Amandito R
- Amandito R
- Amandito R
- Amandito R
- Ambrona-Zafra D
- Ambrozeviciute V
- Ameen M
- Amer MA
- Amin HAA
- Amin J
- Amin J
- Amjad M
- Ammar M
- Ammar MS
- Amoah M
- Amoako J
- Amoako PT
- Amoako-Boateng M
- Amole I
- Amreia M
- Amreia M
- Anandkumar D
- Anderson D
- Anderson F
- Anderson R
- Anderson-Knight H
- Andersson L
- Andika FFA
- Andreotti D
- Andres Garcia-Marin J
- Andress C
- Andriola V
- Ang YL
- Angelieri D
- Anis E
- Ansaloni L
- Ansaloni L
- Ansaloni L
- Ansaloni L
- Ansaloni L
- Antar S
- Antezana D
- Anthoulakis C
- Anthoulakis C
- Antoniozzi A
- Anwar AW
- Anwar N
- Anwer W
- Anyanwu L-J
- Anyanwu L-J
- Aonzo P
- Appeadu-Mensah W
- Appiah EK
- Aql S
- Aquilino F
- Arachchi PP
- Arachchige LAJJ
- Arafa O
- Arafa S
- Arango MCM
- Arango MCM
- Aranzabal Durand SY
- Araujo R
- Arcudi C
- Ardley R
- Arenas A
- Arevalo Azmitia JR
- Arias Pacheco RD
- Arman S
- Arman S
- Armando ChunguiBravo J
- Armellini A
- Arnaud A
- Arnaud AP
- Arnaud AP
- Arnaud AP
- Arroyo Basto CA
- Arshad MM
- Arslan E
- Arsyad HM
- Arthur T
- Arulampalam T
- Aruldas N
- Asal M
- Asar YH
- Asare-Bediako K
- Asele FA
- Ashour A
- Ashour A
- Ashour K
- Ashraf SF
- Ashtari M
- Ashton A
- Asi F
- Asilah SMD
- Assal A
- Assouto PA
- Asturia S
- Asumah H
- Ata A
- Ata AAA
- Ata AY
- Atiyeh A
- Atkins ET
- Atkinson K
- Atobatele K
- Attallah NA
- Attard M
- Attia A
- Attia AM
- Augestad KM
- Aung KP
- Austraite A
- Aviles S
- Avoka A
- Awad I
- Awad SA
- Awadallah S
- Awuku-Asabre J
- Ayad S
- Ayandipo O
- Ayandipo OO
- Aydin MC
- Ayyar S
- Aziz DNA
- Aziz MRA
- Aziz NA
- Azizeldine MG
- Azmitia Mendizabal CA
- Azodo IA
- Azzie G
- Azzie G
- Azzis O
- Baba S
- Bachri H
- Badawy M
- Badenjki MA
- Badicel M
- Badr A
- Badr MFM
- Badwi NM
- Badwi NM
- Badwy A
- Bahar S
- Baheeg M
- Bailey K
- Baillie K
- Baillie K
- Baird A
- Bakhaidar M
- Baki BE
- Bakr A
- Bakry HM
- Bala M
- Balalis D
- Baldacchino M
- Balducci G
- Balila RMH
- Balkan AZA
- Ballouhey Q
- Balmaceda R
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- El Shoura Y
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- El-Dien KS
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- El-Kashef H
- El-Latif NK
- El-Ma'doul AS
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- El-Sagheer N
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- Elazoul M
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- Elbisomy KH
- Eldafrawy M
- Eldamaty L
- Eldeeb AZ
- Eldeen EA
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- Elebute O
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- Elena G
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- Elfiky M
- Elfil M
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- Elgendy FI
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- Elhadad A
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- Elhalawany E
- Elhamouly S
- Elhelbawy MS
- Elhendawy A
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- Elhoseny G
- Elhusseiny AAE
- Elizabeth Lopez C
- Elkadsh I
- Elkady F
- Elkelany A
- Elkelany A
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- Elkhadrawi M
- Elkhalek EA
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- Elsawahly DME
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- Elsherbiny AS
- Elsherif FA
- Elshobary M
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- Elsorogy DEAA
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- Elzahed N
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- Elzowawi F
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- Emara E
- Emile S
- Eng C
- English W
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- Escalante Salas MDC
- Espin-Basany E
- Espinoza F
- Essam A
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- Evajelista CV
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- Farouk SAM
- Farquharson A
- Farrugia A
- Farrugia A
- Faruq A
- Fathy AM
- Fattah AA
- Fatuga A
- Faturoti O
- Faturoti O
- Faure A
- Fautz T
- Favero A
- Fawzy A
- Feidantsis T
- Felipe CO
- Fergany A
- Fergusson SJ
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- Ibrahim A
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- Karabelias G
- Karabulut K
- Karahan SR
- Karakahya M
- Karandikar S
- Karandikar S
- Kariem N
- Karim A
- Karim R
- Karim S
- Karismaningtyas H
- Karjiker P
- Karkeet M
- Karkeet M
- Karlo R
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- Karousos D
- Karumnas P
- Kaselis N
- Kaselis N
- Kasem E
- Kasem EA
- Kasputyte S
- Kaul A
- Kazanavicius D
- Kedar A
- Kefalidi E
- Keke KR
- Kelany M
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- Kennedy ED
- Kennedy M
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- Kesinger M
- Khafagy T
- Khairy H
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- Khajanchi M
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- Khalifah E
- Khalili M
- Khalique A
- Khallaf S
- Khamajeet A
- Khan A
- Khan K
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- Khan R
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- Khatri C
- Khatri C
- Khattab K
- Khedr AE-RH
- Khoja A
- Khoja A
- Khokha D
- Khokha V
- Khosla S
- Khouri Ferreira SA
- Khreishi R
- Khreishi R
- Khulu LB
- Khyrallh A
- Kiasat A
- Kidd T
- Kielty P
- Kim MY-H
- Kim S-H
- Kim SB
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- Kinandu K
- King R
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- Kirby A
- Kirishnan A
- Kirupagaran A
- Kiudelis M
- Kjellin A
- Klappenbach R
- Knight S
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- Koay KL
- Kobal BB
- Koh C
- Koh H
- Koh PY
- Koh S
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- Kojo ATT
- Kojo ATT
- Kojo ATT
- Kolosov A
- Komolafe O
- Kondrotas P
- Kong C
- Kong SN
- Kong V
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- Konstantina K
- Kontos M
- Kordorwu HEK
- Korkolis D
- Kosai NR
- Kosai NR
- Kose E
- Koskenvuo L
- Kostov E
- Kotb AHE-B
- Kotecha D
- Koto MZ
- Kotobi H
- Koumpa F
- Kouraklis G
- Kourdouli A
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- Kretzmann H
- Krishna K
- Kruspi S
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- Kumar B
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- Kyriazanos I
- Kyrou G
- Kyziridis D
- L'Heveder A
- La Brocca A
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- Labib P
- Ladukas A
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- Lakshmi HN
- Lam FY
- Lam JCY
- Lam WH
- Lamanna GL
- Lanau MIV
- Lando J
- Landolfo G
- Landolfo G
- Lap G
- Lapitan MC
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- Lasek A
- Lasheen A
- Lasheen KT
- Latif A
- Laugzemys E
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- Laurie K
- Lauzikas G
- Law JH
- Lawal A
- Lawal AO
- Lawal T
- Lawal TA
- Lawani I
- Lawther R
- Lazzari G
- Lazzari V
- Lazzarini Cury AD
- Le VTH
- Leal A
- Leal M
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- Lecompte J-F
- Lee C
- Lee EX
- Lee F
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- Lee KY
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- Leppaniemi A
- Leppaniemi A
- Leroux J
- Leung KW
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- Leusink A
- Lewis J
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- Li KKK
- Li WS
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- Liew I
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- Lilford R
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- Lim G
- Lim H
- Lim J
- Lim PJ
- Lim SJ
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- Lim SY
- Limache S
- Limaye N
- Limoges B
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- lo Conte A
- loaloa MR
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- Macchitella Y
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- Macfarlane A
- Machaca M
- Machain Vega GM
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- Maciejec L
- Madiba T
- Madkor MH
- Madrid Barrientos LA
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- Magdy H
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- Magee C
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- Manfreda S
- Mangan C
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- Martian B-V
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- Mirza A
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- Mistry A
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- Mohamed A
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- Mohamed B
- Mohamed F
- Mohamed I
- Mohamed M
- Mohamed MA
- Mohamed MAEH
- Mohamed MM
- Mohamed O
- Mohamed SR
- Mohameden A
- Mohammad A
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- Mohammed A
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- Mohammed MMH
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- Montoya Botero JA
- Montrimaite M
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- Moodley Y
- Moore R
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- Mosalum O
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- Mousa M
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- Nwabuoku E
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- Ruiz Panez W
- Ruiz-Tovar J
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- Rutkowski W
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- Saadeh R
- Saami M
- Saar S
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- Sabour FA
- Sabry A
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- Sadig N
- Saeed AM
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- Safa H
- Sahbaz NA
- Sahel S
- Saidbadr A
- Sakr A
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- Salah OM
- Salama M
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- Sallinen V
- Sallinen V
- Salma M
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- Salma U
- Salman A
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- Samalavicius NE
- Samaraweera DI
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- Samir A
- Samison LH
- Sammarco G
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- Samy S
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- Sandler S
- Sandoval Barrantes AM
- Sanni HA
- Sanz S
- Sapci I
- Saqlain M
- Sarafilovic H
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- Sarsik S
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- Sasia D
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- Scalabre A
- Scalabre A
- Schadde E
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- Schivo D
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- Scott M
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- Semeda N
- Semiz A
- Sena-Ruiz F
- Senanayake KJ
- Senanayake WSMKJ
- Setiawan J
- Seto DM
- Seyoum N
- Sfougaris D
- Sgroi G
- Shaalan M
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- Shachykava T
- Shah A
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- Shaharuddin S
- Shahbaz AR
- Shaheen A
- Shahine A
- Shahzad N
- Shaikh N
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- Yeung MHA
- Yifieyeh A
- Yildirim R
- Yip C
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- Yoganathan P
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- Yong CO
- Yong GL
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- Zapata Ponze De Leon M
- Zapata Ponze De Leon M
- Zapata F
- Zarb C
- Zardab A
- Zegarra S
- Zeidan S
- Zelada Alvarez II
- Zerihun AB
- Zeta Solis LA
- Zhang Z
- Zheng F
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- Ziubryte G
- Zohair A
- Zorrilla CD
- Zuber M
- Zuber M
- Zuk G
- Zulkifli A
- Zumbuhl L
- Publication venue
- Publication date
- 15/10/2018
- Field of study
Background The World Health Organization (WHO) Surgical Safety Checklist has fostered safe practice for 10 years, yet its place in emergency surgery has not been assessed on a global scale. The aim of this study was to evaluate reported checklist use in emergency settings and examine the relationship with perioperative mortality in patients who had emergency laparotomy. Methods In two multinational cohort studies, adults undergoing emergency laparotomy were compared with those having elective gastrointestinal surgery. Relationships between reported checklist use and mortality were determined using multivariable logistic regression and bootstrapped simulation. Results Of 12 296 patients included from 76 countries, 4843 underwent emergency laparotomy. After adjusting for patient and disease factors, checklist use before emergency laparotomy was more common in countries with a high Human Development Index (HDI) (2455 of 2741, 89.6 per cent) compared with that in countries with a middle (753 of 1242, 60.6 per cent; odds ratio (OR) 0.17, 95 per cent c.i. 0.14 to 0.21, P <0001) or low (363 of 860, 422 per cent; OR 008, 007 to 010, P <0.001) HDI. Checklist use was less common in elective surgery than for emergency laparotomy in high-HDI countries (risk difference -94 (95 per cent c.i. -11.9 to -6.9) per cent; P <0001), but the relationship was reversed in low-HDI countries (+121 (+7.0 to +173) per cent; P <0001). In multivariable models, checklist use was associated with a lower 30-day perioperative mortality (OR 0.60, 0.50 to 073; P <0.001). The greatest absolute benefit was seen for emergency surgery in low- and middle-HDI countries. Conclusion Checklist use in emergency laparotomy was associated with a significantly lower perioperative mortality rate. Checklist use in low-HDI countries was half that in high-HDI countries.Peer reviewe
The role of preclinical SPECT in oncological and neurological research in combination with either CT or MRI
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- A Bitar
- A Greco
- A Kielland
- A Merron
- A Nakazawa
- A Ruggiero
- A Sanchez-Crespo
- AB Hwang
- AB Hwang
- AG Ceulemans
- AJ Studwell
- AM Catafau
- AM LeBeau
- AR Penheiter
- AW Sauter
- B Man De
- B Vastenhouw
- BF Hutton
- BJ Pichler
- C Depboylu
- C Forstner von
- C Ji
- C Jongen
- C Muller
- C Muller
- C Müller
- C Scherfler
- C Scherfler
- C Templin
- C Vangestel
- C Vanhove
- C Wu
- C Wu
- C Wu
- CC Tsai
- CL Chen
- CL Crunelle
- CL Crunelle
- CL Crunelle
- CT Badea
- D Alvarez-Fischer
- D Beque
- D Beque
- D Hanahan
- D Hanahan
- D Martinez
- D Meier
- D Weerakkody
- DK Marsee
- DM Goldenberg
- E Breton
- E Ruoslahti
- E Teng
- EF Vries de
- F Cavallo
- F Forrer
- F Have van der
- F Have van der
- F Have van der
- FJ Beekman
- Freek J. Beekman
- FY Huang
- FY Yang
- G Andringa
- G Mariani
- G Paxinos
- G Shao
- GK Kastis
- H Fujii
- H Hong
- I Apostolova
- I Tsiapa
- I Willekens
- IJ Hildebrandt
- IO Umeda
- J Booij
- J Booij
- J Booij
- J Booij
- J Li
- J Lofblom
- J Nuyts
- J-W Tan
- JA Gleave
- Jan Booij
- JB Habraken
- JC Reubi
- JD Lee
- JE Bowsher
- JP Schlomka
- JS Baba
- JV Jokerst
- K Abiraj
- K Herholz
- K Movahedi
- K Ogawa
- KH Ma
- L Aloj
- L Han
- L Joosten
- L Ritschl
- LR Furenlid
- LT Chang
- M Bauwens
- M Defrise
- M Essen van
- M Fani
- M Figee
- M Inubushi
- M Jong de
- M Laruelle
- M Laruelle
- M Laruelle
- M Melis
- M Saint-Hubert De
- M Schottelius
- M Smet de
- M Stabin
- M Ziebell
- MA Moroz
- MA Nader
- Marion de Jong
- MC Goorden
- MF Smith
- MM Ali
- MM Doubrovin
- MM Ponsen
- MM Svedberg
- MM Welling
- Monique R. Bernsen
- MP Kung
- MP Kung
- MR Bernsen
- MR Bernsen
- N Devoogdt
- N Kondo
- NU Schramm
- P Vaupel
- P Weinmann
- PD Acton
- PD Acton
- PE Vaissier
- Pieter E. B. Vaissier
- PL Chow
- R Bar-Shalom
- R Golestani
- R Madru
- R Weissleder
- RA Kemp de
- RK Rowe
- Roel Van Holen
- RP Brinkhuis
- RS Fisher
- S Bredow
- S Deleye
- S Gargiulo
- S Heskamp
- S Kimura
- S Macholl
- S Nikolaus
- S Nikolaus
- S Nimmagadda
- SD Metzler
- SJ Kish
- SJ Schambach
- SK Carlson
- SP Williams
- T Funk
- T Olafsen
- T Wyckhuys
- T Xie
- T Zeniya
- TF Massoud
- TK Nayak
- V Ambrosini
- V Keereman
- V Kersemans
- V Kersemans
- W Branderhorst
- W Bult
- WP Deng
- Y Zhou
- YC Chen
- YJ Chang
- YR Huang
- Z Liu
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Global variation in anastomosis and end colostomy formation following left-sided colorectal resection
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- Aahlin Ek
- Aamer A
- Aaniana K
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- Abbasy J
- Abbo O
- Abbo O
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- Abbouch M
- Abd-Elmawla M
- Abd-Elrasoul Y
- Abdallah E
- Abdallah E
- Abdel-Aty A
- Abdel-Hameed N
- Abdel-Kader Sm
- Abdel-Wahab Nye
- Abdelaal A
- Abdelaty M
- Abdelazeam Ar
- Abdelazim G
- Abdelaziz Ma
- Abdelbadeai K
- Abdelfatah A
- AbdelFattah I
- Abdelgelil A
- Abdelghany S
- Abdelhady S
- Abdelhamed R
- Abdelhamid A
- Abdelhaq A
- Abdelkader M
- Abdelkader M
- Abdelkader O
- Abdelkareem A
- Abdelkhalek M
- Abdelmageed E
- Abdelmotaleb I
- Abdelraheim M
- Abdelraouf Am
- Abdelrouf Dm
- Abdelshafy M
- Abdelshakour M
- Abdrabou Ak
- Abdul-Latif S
- Abdulaziz H
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- Adawi M
- Adebanjo A
- Adebanjo A
- Adebola O
- Adedeji A
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- Ademuyiwa Ao
- Ademuyiwa Ao
- Ademuyiwa Ao
- Adenekan B
- Adeniran J
- Adeniran J
- Adeniyi A
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- Adesanya O
- Adesanya O
- Adesina A
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- Adesuyi A
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- Adhitama N
- Adil M
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- Adnan Ab
- Adu-Aryee N
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- Agius M
- Aglan A
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- Aguilar-Jimenez J
- Aguilera M
- Aguilera Ml
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- Aguilera-Arevalo Ml
- Ahlonsou G
- Ahlqvist S
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- Aigrain Y
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- Al Attar SM
- Al Awwad S
- Al Barrawi FE
- Al Bastawis F
- Al Meligy A
- Al Rafati AAR
- Al Raouf EA
- Al Saied G
- Al Subaie N
- Al-Aarag Aa
- Al-Azraqi Iaa
- Al-Bahrani A
- Al-Buhaisi A
- Al-Dakka E
- Al-Faifi Jj
- Al-Faqawi M
- Al-Farram H
- Al-Hameedi Hii
- Al-Hasani Rkmj
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- Arachchige Lajj
- Arafa O
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- Arango Mcm
- Arango Mcm
- Arango Mcm
- Arango Mcm
- Araujo Jslr
- Arcudi C
- Ardley R
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- Arnaud Ap
- Arshad Mm
- Arslan E
- Arsyad Hm
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- Arulampalam T
- Aruldas N
- Asaat Ul Razi S
- Asal M
- Asar Yh
- Asare-Bediako K
- Asele Fa
- Ashour A
- Ashour A
- Ashour K
- Ashraf Sf
- Ashtari M
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- Asi F
- Asilah Smd
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- Ata Aaa
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- Atobatele K
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- Attia Am
- Augestad Km
- Aung Kp
- Austraite A
- Aviles S
- Avoka A
- Awad I
- Awad Sa
- Awadallah S
- Awuku-Asabre J
- Ayad S
- Ayandipo O
- Ayandipo Oo
- Aydin Mc
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- Aziz Mra
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- Azzie G
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- Badr Mfm
- Badwi Nm
- Badwi Nm
- Badwy A
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- Baillie K
- Baillie K
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- Bakhaidar M
- Baki Be
- Bakr A
- Bakry Hm
- Baky Fahmy MA
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- Baldacchino M
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- Balmaceda R
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- Bamford R
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- Barendegere V
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- Barmayehvar B
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- Barnacle J
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- Barreda Lma
- Barrientos Lam
- Barrios E
- Barrios E
- Barrios E
- Barry J
- Basilicò
- Basir Erm
- Bassem M
- Bassit Ka
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- Bautista Acm
- Bayram S
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- Bediako-Bowan A
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- Beisa V
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- Bekhet Nm
- Beleñ
- Belkouchi A
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- Benammi S
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- Benevento A
- Benger M
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- Benyaiche C
- Bermú
- Bernardo Cg
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- Beuran M
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- Bezzina M
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- Bhatnagar A
- Bhattacharya S
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- Bhopal Kf
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- Birring A
- Bisset C
- Bjö
- Bjö
- Blacker S
- Blackwell J
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- Blanco-Colino R
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- Blencowe N
- Bliksø
- Blower E
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- Blundell R
- Boakye-Yiadom K
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- Boddy A
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- Bode C
- Bodur S
- Boereboom C
- Boggon A
- Boijsen M
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- Bonavia K
- Bonavina L
- Bonavina L
- Bond-Smith G
- Bondin J
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- Bondurri A
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- Borg E
- Borg E
- Borin E
- Bortolasi L
- Bortolasi L
- Boshnaq M
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- Bougard H
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- Bowabsak A
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- Bowley D
- Bowling K
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- Boyce T
- Bré
- Bradulskis S
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- Breistrand M
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- Bukari M
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- Bustangi N
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- Cardozo Jt
- Cardozo Ram
- Careta Mc
- Carlucci M
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- Carpio J
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- Cassar K
- Castillo Vdp
- Castro Mr
- Catani M
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- Chachulski W
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- Chai Fy
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- Chan Z
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- Chang Ky
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- Chin Yr
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- Chiong Jac
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- Chiu S
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- Chong Hy
- Chong Hy
- Choudhry A
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- Chowdhury D
- Chu K
- Chun A
- Chun T
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- Chung S
- Ciccioli E
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- Clegg-Lampety Jn
- Clegg-Lamptey Jn
- Clement Kd
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- Contreras E
- Contreras-Vergara Al
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- Corbellini C
- Corbellino M
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- Correa Jc
- Corro-Diaz S
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- Costa-Maia J
- Costas-Chavarri A
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- Court E
- Cox D
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- Dé
- D&apos
- D&apos
- D&apos
- D&apos
- D&apos
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- Da Silva LA
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- Dan I
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- Daniyan M
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- Daqeeq A
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- Das A
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- Dasari M
- Dashnyam E
- Dassah V
- Datta U
- Davenport R
- Davies J
- Davies R
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- Dawnay G
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- Dayie M
- De Boni D
- De Bono P
- De Bono P
- De Castro Segundo LCB
- De Franciscis S
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- De La Medina AR
- de Leó
- De Leon MZP
- De Leon MZP
- de Lima CVB
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- Del Basso C
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- Delgado Msftl
- Dell A
- Dempster E
- Denewar A
- Depalma N
- Deputy M
- Der Y
- Dervenis C
- Despotidis V
- Desta S
- Deutschmann P
- Devadasar Gh
- Dharamshi Ha
- Dhillon D
- Di Franco F
- Di Martino N
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- Di Saverio S
- Diab A
- Diaconescu B
- Diaconescu Ib
- Dias S
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- Diaz-Zorrilla C
- Dick L
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- Dindyal S
- Dissanayake T
- Djivoh F
- Domini E
- Domini E
- Donnelly P
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- Dorani Rmnr
- Dorismé
- Dos Santos DV
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- Drake Tm
- Driscoll A
- Drungilas M
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- Dueñ
- Duffy L
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- Durand Sya
- Dwydar A
- Ebdewi H
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- Eduard P
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- El Kashash A
- El Kholy A
- El Magd AA
- El Mesery S
- El Salam YA
- El Sayed GS
- El Sayed IM
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- El-Dien Ks
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- El-Gizawy E
- El-Hamouly As
- El-Kashef H
- El-Latif Nka
- El-Ma&apos
- El-Rabaa S
- El-Sagheer N
- El-Salam Fa
- El-Sawy A
- El-Sehily A
- El-Shahat Ns
- El-Sheemy H
- El-Taher E
- Elabdin Hz
- Elashmawy M
- Elashry R
- Elazab A
- Elazayem Aa
- Elazoul M
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- Elbanby Es
- Elbatahgy A
- Elbe P
- Elbermawy M
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- Eldeen Ea
- Eldin Mab
- Elebute O
- Elebute O
- Elena G
- Elfarargy A
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- Elfeki H
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- Elfouly Y
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- Elgendy Fi
- Elgheriany M
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- Elhendawy A
- Elhendawy Aoa
- Elhoseny G
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- Elkadsh I
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- Elkelany A
- Elkelany A
- Elkhadrawi M
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- Elkholy A
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- Elkolaly Ss
- Elkorashy Am
- Ellison Q
- Elmashala A
- Elmasry M
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- Elmihy S
- Elnagar A
- Elnajjar Ma
- Elnemr Ae
- Elrasoul Ya
- Elrazek Aa
- Elsabbagh N
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- Elsawahly Dme
- Elsawy A
- Elsayed M
- Elsayed M
- Elsayed N
- Elsayed Nar
- Elsayed Zm
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- Elsehimy M
- Elsemelawy R
- Elshaar M
- Elshaer K
- Elshaer M
- Elshaer M
- Elshafay Ae
- Elshami M
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- Elsharkawy Aa
- Elsheikh S
- Elsherbiney S
- Elsherbiny As
- Elsherif Fa
- Elshobary M
- Elsiddig M
- Elsobky S
- Elsorogy Deaa
- Elwaey A
- Elwakil H
- Elwan A
- Elwan A
- Elwy E
- Elzahed N
- Elzayat I
- Elzayat M
- Elzayyat I
- Elzowawi F
- Emadeldin D
- Emadeldin H
- Emara E
- Emile S
- Eng C
- English W
- Esam A
- Escobar Eg.
- Espin-Basany E
- Espinoza F
- Espinoza Kt
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- Essam A
- Essam Aa
- Essam M
- Essoun S
- Esteban E
- Estee Mm
- Estupinian S
- Etchill E
- Etchill E
- Etienne S
- Etman M
- Etwire V
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- Evans E
- Eysa A
- Eyssartier E
- Ezzat E
- Ezzat T
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- Fahiem A
- Fahim M
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- Fairfield C
- Fairfield C
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- Falco N
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- Farag A
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- Farah A
- Farahat Mm
- Faraz A
- Fares M
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- Farhan-Alanie Mmh
- Farhangmehr N
- Farinella E
- Farmakis K
- Farooq T
- Farouk Sam
- Farquharson A
- Farrugia A
- Farrugia A
- Faruq A
- Fathy Am
- Fattah Aa
- Fatuga A
- Faturoti O
- Faturoti O
- Faure A
- Fautz T
- Favero A
- Fawzy A
- Feidantsis T
- Felipe Co
- Fergany A
- Fergusson Sj
- Fergusson Sj
- Fergusson Sj
- Fermani C
- Fermani Cg
- Ferná
- Fernandes C
- Fernandez-Bueno F
- Fernandez-Vega L
- Ferousis C
- Ferreira Sak
- Ferrero E
- Fievet L
- Filatau A
- Findlay-Cooper K
- Firdouse M
- Firdouse M
- Firdouse M
- Firwana A
- Fitsum A
- Fitzgerald Je
- Florez Ljg
- Foco M
- Fok Cyj
- Fontana T
- Foo Cc
- Forlin L
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- Fouad D
- Fouad D
- Fourcade L
- Fowler Aj
- Fozard T
- Fozard T
- Frade F
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- Francois P
- Francois-Coridon H
- Francone E
- Freitas Av
- Frey D
- Frisk B
- Fuentes-Rivera L
- Fujii F
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- Gaarder T
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- Gad Mo
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- Gadhvi V
- Gado A
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- Gaignard E
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- Gala T
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- Galiqi G
- Galleano R
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- Gamal D
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- Gamil D
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- Garaycochea O
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- Gerosa A
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- Grobler Dc
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- Guevara R
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- Gulielmi A
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- Gustafsson U
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- Halhouli O
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- Halicioglu I
- Hall E
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- Hamarshi A
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- Hamdan A
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- Hany E
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- Hashad E
- Hasheminia A
- Hashim A
- Hashish A
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- Haslegrave A
- Hasnan Mb
- Hassaan A
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- Hassan I
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- Hassanein Ab
- Havemann I
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- Huwait A
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- Iannone I
- Ibraheem Aa
- Ibraheem Hi
- Ibrahem Aa
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- Ibrahim A
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- Ibrahim Am
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- Ibrahim I
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- Ibrahim M
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- Iftekhar F
- Iftikhar Z
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- Ignatavicius P
- Ihediwa G
- Imoro O
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- Ioannidis O
- Iordache Fm
- Iqbal Fm
- Iqbal Mr
- Ireland P
- Irtan S
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- Irwin G
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- Ishak N
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- Jeffery A
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- Jenner E
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- Kabariti R
- Kabariti R
- Kabba J
- Kabongo K
- Kache S
- Kaci Aa
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- Kalakouti E
- Kalles V
- Kalles V
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- Kamarulzamil Sna
- Kamil R
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- Kanani A
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- Kandil H
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- Karabacak U
- Karabelias G
- Karabulut K
- Karahan Sr
- Karakahya M
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- Karandikar S
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- Karim R
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- Karjiker P
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- Karlo R
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- Karousos D
- Karumnas P
- Kaselis N
- Kaselis N
- Kasem E
- Kasem Ea
- Kasputyte S
- Kaul A
- Kazanavicius D
- Kedar A
- Kefalidi E
- Keke Kr
- Kelany M
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- Kennedy Ed
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- Kerley R
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- Khairy H
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- Khaled H
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- Khg Li
- Khoja A
- Khoja A
- Khokha D
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- Khosla S
- Khreishi R
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- Khulu Lb
- Khyrallh A
- Kiasat A
- Kidd T
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- Kim My
- Kim Sb
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- Kinandu K
- King R
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- Kiudelis M
- Kjellin A
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- Klappenbach R
- Knight S
- Koay Kl
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- Kolosov A
- Komolafe O
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- Kong C
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- Kose E
- Koskenvuo L
- Kostov E
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- Kotecha D
- Koto Mz
- Kotobi H
- Koumpa F
- Kouraklis G
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- Kwatiwani C
- Kwizera S
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- Kyereh M
- Kyriazanos I
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- Kyziridis D
- Ló
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- La Brocca A
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- Labib P
- Ladukas A
- Lafferty K
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- Lam Fy
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- Landolfo G
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- Lasek A
- Lasheen A
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- Latif A
- Laufer Lav
- Laugzemys E
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- Laurie K
- Lauzikas G
- Law Jh
- Lawal A
- Lawal Ao
- Lawal T
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- Lawani I
- Lawther R
- Lazzari G
- Lazzari V
- Leal A
- Leal M
- Lecompte Jf
- Lee C
- Lee Ex
- Lee F
- Lee K
- Lee Kc
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- Leone N
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- Leung Kw
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- Leusink A
- Lewis J
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- Lim G
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- Loaloa Mr
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- Macchitella Y
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- Macfarlane A
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- Margaritis M
- Mariani A
- Marinkovic B
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- Marks E
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- Marret Jb
- Marshall Dc
- Martian Bv
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- Mentula P
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- Miranda C
- Mircea H
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- Mironescu A
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- Mirza A
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- Mistry A
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- Mitroudi M
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- Modolo Mm
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- Moe Tt
- Mogan Yp
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- Mohamed A
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- Mohamed Ar
- Mohamed B
- Mohamed F
- Mohamed I
- Mohamed M
- Mohamed Ma
- Mohamed Maeh
- Mohamed Mm
- Mohamed O
- Mohamed Sr
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- Mohammad A
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- Molina G
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- Monaghan E
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- Monrad-Hansen Pw
- Montejo Msg
- Monteleone M
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- Montes I
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- Montrimaite M
- Montrimaite M
- Moodley Y
- Moore R
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- Mora Jjv
- Morais Pab
- Morales C
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- Morandi E
- Moreira G
- Moreno Sc
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- Morsi A
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- Mosad A
- Mosalum O
- Mostafa Ha
- Mostafa M
- Mostafa M
- Mousa M
- Moussa O
- Moustafa A
- Mouttalib S
- Mowafy B
- Mphatsoe Am
- Mshelbwala P
- Msiska N
- Msosa V
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- Muddebihal U
- Mukin Adf
- Muktar U
- Mukuzunga C
- Muller C
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- Munera A
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- Munipalle Pc
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- Musa Aek
- Musleh A
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- Mutlu D
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- Muzio E
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- Nabawi A
- Nada F
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- Nanthakumaran S
- Napolitano L
- Napolitano L
- Naqvi Sa
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- Naranjo Aristizã
- Narayanan R
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- Ndlovu Sr
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- Negida A
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- Nepogodiev D
- Nepogodiev D
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- Nesaratnam A
- Nessa A
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- Nevieraite V
- Newton T
- Ng S
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- Njokanma I
- Nnajiuba H
- Nocito A
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- Notarnicola M
- Nouh T
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- Noukpozounkou B
- Novak A
- Nowers J
- Nsengimana Vjp
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- Ntirenganya F
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- Nwabuoku E
- Nwinee V
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- Nyberg J
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- O&apos
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- Obute Rd
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- Odeyemi B
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- Odutola O
- Ogunsua O
- Ogunyemi A
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- Samaniego Cs
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- Scott M
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- Seisay S
- Selvaggi F
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- Semeda N
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- Senanayake Kj
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- Senanayake W
- Septiem Jg
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- Sfougaris D
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- Shu S
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- Shukla J
- Shwky A
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- Siguantay M
- Sigurdadottir J
- Sii Ssy
- Sila Gcm
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- Sileri P
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- Silvestri V
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- Simutis G
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- Skardž
- Skehan J
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- Smart N
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- Snyder E
- Sobnach S
- Sodde P
- Soeselo Da
- Sokratous A
- Solaini L
- Soldevila-Verdeguer C
- Soley R
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- Soliman A
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- Soliman N
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- Song J
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- Souaibou Yi
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- Srinivasan R
- Sriram A
- Sroor F
- Sruogiene Ez
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- Stasinou T
- Steccanella F
- Stefanopoulos A
- Stephen A
- Stewart D
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- Stock S
- Stoddart M
- Stoddart M
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- Stourton F
- Strazdas A
- Strupas K
- Strupas K
- Strupas K
- Stuva J
- Stuva Jpg
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- Suá
- Suarez A
- Suarez Aab
- Subocius A
- Suleiman Si
- Summerour V
- Sund M
- Sund M
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- Tanase A
- Tanase A
- Tang A
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- Tani Si
- Tansoker I
- Tarek A
- Tarek A
- Tarek D
- Targa S
- Tariq S
- Tata Md
- Tatagiba Ls
- Tawfik Ba
- Tawfik G
- Tawfik G
- Taylor F
- Teasdale E
- Teasdale E
- Teasdale E
- Teasdale E
- Tedeschi U
- Tedjaatmadja C
- Telfah Mm
- Tembo T
- Temoche E
- Tennakoon A
- Teo Sy
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- Thabet W
- Thalgaspitiya Spb
- Tham Jc
- Thanusan V
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- Theodosopoulos T
- Thollot A
- Thomas E
- Thompson B
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- Thurairaja R
- Ticona Wa
- Tierney G
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- Timothy Ok
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- To K
- To K
- Todd O
- Toeema Ag
- Tolba H
- Tolg C
- Tolonen M
- Tolotra Tec
- Tori Sa
- Torrance Hd
- Torrance Hd
- Torres Cpg
- Torres Sg
- Toto Ö
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- Tselos A
- Tshisola Sk
- Tugnoli G
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- Turati L
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- Tutino R
- Tverskis Z
- Tyler R
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- Uš
- Ubhi Hk
- Ubiali P
- Ugalde P
- Ukwenya Y
- Uluş
- Ulusahin M
- Upadhyaya V
- Upchurch E
- Urbanavicius L
- Urbonas T
- Urbonas T
- Urniež
- Urniezius Z
- Urquizu Mc
- Usaityte A
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- Vaicius A
- Valcarcel-Saldañ
- Valioulis I
- Van Der Naald N
- Van Duren B
- Van Niekerk M
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- Varcada M
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- Vartanoglu T
- Vartic M
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- Vasquez G
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- Velasquez R
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- Venskutonis D
- Venskutonis D
- Venskutonis D
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- Wagener M
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- Waleed H
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- Walsh U
- Waqar M
- Ward Ae
- Ward S
- Warda M
- Warren O
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- Warwick Am
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- Yavuz Ma
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- Yeung En
- Yeung Mha
- Yifieyeh A
- Yildirim R
- Yip C
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- Publication venue
- 'Wiley'
- Publication date
- 27/11/2018
- Field of study
Background
End colostomy rates following colorectal resection vary across institutions in high-income settings, being influenced by patient, disease, surgeon and system factors. This study aimed to assess global variation in end colostomy rates after left-sided colorectal resection.
Methods
This study comprised an analysis of GlobalSurg-1 and -2 international, prospective, observational cohort studies (2014, 2016), including consecutive adult patients undergoing elective or emergency left-sided colorectal resection within discrete 2-week windows. Countries were grouped into high-, middle- and low-income tertiles according to the United Nations Human Development Index (HDI). Factors associated with colostomy formation versus primary anastomosis were explored using a multilevel, multivariable logistic regression model.
Results
In total, 1635 patients from 242 hospitals in 57 countries undergoing left-sided colorectal resection were included: 113 (6·9 per cent) from low-HDI, 254 (15·5 per cent) from middle-HDI and 1268 (77·6 per cent) from high-HDI countries. There was a higher proportion of patients with perforated disease (57·5, 40·9 and 35·4 per cent; P < 0·001) and subsequent use of end colostomy (52·2, 24·8 and 18·9 per cent; P < 0·001) in low- compared with middle- and high-HDI settings. The association with colostomy use in low-HDI settings persisted (odds ratio (OR) 3·20, 95 per cent c.i. 1·35 to 7·57; P = 0·008) after risk adjustment for malignant disease (OR 2·34, 1·65 to 3·32; P < 0·001), emergency surgery (OR 4·08, 2·73 to 6·10; P < 0·001), time to operation at least 48 h (OR 1·99, 1·28 to 3·09; P = 0·002) and disease perforation (OR 4·00, 2·81 to 5·69; P < 0·001).
Conclusion
Global differences existed in the proportion of patients receiving end stomas after left-sided colorectal resection based on income, which went beyond case mix alone
Allelopathic effects of the revegetation species Juniperus sabina L. in semiarid areas of China
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Estimation of 1-D velocity models beneath strong-motion observation sites in the Kathmandu Valley using strong-motion records from moderate-sized earthquakes
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
- …