2,403 research outputs found
Gulf of Maine seals - fisheries interactions and integrated research : final report
Meeting held: October 28, 2011, Provincetown Center for Coastal Studies, Provincetown, MA. Sponsored by the Marine Mammal Center at the Woods Hole Oceanographic
Institution and the Provincetown Center for Coastal StudiesThe 2011 meeting, “Gulf of Maine Seals: Fisheries Interactions and Integrated Research”, held at
the Provincetown Center for Coastal Studies (PCCS), featured posters and oral presentations as
well as a series of discussion groups. This meeting was a follow up to the 2009 meeting, “Gulf
of Maine Seals - Populations, Problems and Priorities”, held at the Woods Hole Oceanographic
Institution (WHOI) (Bogomolni et al. 2010). At the conclusion of the 2009 meeting, attendees
emphasized the need to improve communication, to obtain funding for long term research, to
continue meeting on a regular basis, to increase data and data sharing, and to support cross
cutting research between the meeting’s three primary topic areas: disease and health; human and
fishery interactions; and population biology. The overarching goals of the 2011 meeting were to discuss and share work to date, present some
of the tools developed since the 2009 meeting, and outline goals for future integrated research.
One of the tools presented within the framework of cross-cutting research areas and integrative
research was the development of a sightings database and website for uniquely identifiable
(unique pelage, scars, lesions, tagged, branded, marked, etc.) animals. The practicality of this
tool as a means to increase communication was discussed.
Additionally, seal/fisheries interactions throughout the Gulf of Maine, Cape Cod and waters off
of the northeast U.S. have continued to concern stakeholders since the 2009 meeting. The
urgency of documenting, understanding and mitigating these interactions has become more
apparent. Therefore, the focus of the 2011 Provincetown meeting was on fisheries interaction
and related topics raised at the last 2009 workshop and in the meetings with Cape Cod fishermen
described below. For the purposes of this report, 'fisheries interaction' can be direct/operational
(e.g. depredation, when seals remove fish from gear; or entanglement/bycatch, when seals are
unintentionally captured), or indirect/ecological (competition, displacement or other large-scale
interactions between seals and fisheries). Stakeholder concerns about fisheries interactions and recent increases in local seal abundance
were rising prior to the 2009 meeting. In December of 2006, the Chatham-based Cape Cod
Commercial Hook Fishermen’s Association (CCCHFA) took the lead in organizing a meeting
entitled, “Structuring a Novel Research Team to Define and Assess the Impact of Human/Seal
Interactions on Cape Cod/Gulf of Maine through Ecosystem-Based Analysis”. Participants
included fishermen, policy makers, environmental organizations and researchers aiming to
develop a unique partnership to study the New England seal population. The goal of this
meeting was to create a research team that would define the ecological role of seals in Cape Cod
waters by studying population dynamics, behavior, and health. This meeting resulted in a
successful partnership, financially aided by the International Fund for Animal Welfare (IFAW),
between fishermen and seal researchers. A cost-effective cooperative research agreement was
reached whereby seal researchers were provided boat transport around the Chatham and
Monomoy areas by local fishermen. This agreement allowed students and researchers to gain
access to areas off of Chatham that would otherwise not have been accessible. It also supported
a collaborative effort to increase understanding and communication between stakeholders. In addition to the CCCHFA-led meeting in 2006, a series of informal meetings have been held
on Cape Cod between commercial and recreational fishermen and marine scientists. This work
was initially funded by the Cape Cod Five Cents Savings Bank Charitable Foundation. Owen
Nichols and Lisa Sette (PCCS) have held individual meetings with commercial fishermen in
Chatham, Orleans, and Provincetown, and recreational fishermen, outfitters, and associations
throughout the Outer Cape. These individual meetings were followed by larger group meetings
in Eastham and Chatham in 2010 and 2011, and more are planned for 2012. Attendees included
commercial and recreational fishermen and scientists, and discussion topics included observed
seal/fishery interactions and potential collaborative research projects. The goal of the meetings
is to develop a working group composed of members of the fishing and scientific communities
with expertise in marine mammal and fisheries ecology.
The above meetings laid the foundation for the 2011 meeting, during which members of the
scientific and fishing communities gathered to focus on fisheries interactions and integrated
research techniques to quantify and mitigate interactions. Several invited presentations were
given, some of which were scheduled (Appendix A) with selected abstracts provided (Appendix
B), and some of which were delivered on an ad hoc basis upon request from organizers or
attendees (see Appendix F for edited transcripts of presentations). In order to ensure that the
fishing community had a distinct voice, a forum was included in the agenda, during which
fishermen were encouraged to share their observations, experiences and concerns. Separately,
moderated discussion groups focused specifically on fisheries interactions, tagging and tracking,
and management issues. All four sessions, despite their specific foci, shared common themes
such as the need for collaborative research involving both the scientific and fishing communities.
Recommendations from the discussion groups and summaries from each session are listed on the
following pages.Funding was provided by the Woods Hole Oceanographic Institution Marine Mammal Center and
the Provincetown Center for Coastal Studie
A review of the Sentusidinium complex of dinoflagellate cysts
The Jurassic to Neogene (Miocene) dinoflagellate cyst genus Sentusidinium has a relatively simple overall morphology. This genus, together with Batiacasphaera, Kallosphaeridium and Pentafidia, comprises the Sentusidinium complex. This is distinct from the superficially similar laterally asymmetrical and subspheroidal/lenticular Cyclonephelium complex. The genus Sentusidinium is an acavate, subcircular, proximate to proximochorate, sexiform gonyaulacacean genus with an apical archaeopyle and typically low relief ornamentation. Since the erection of Sentusidinium in 1978, three similar genera have been established, which we consider to be taxonomic junior synonyms of that genus: Barbatacysta, Escharisphaeridia and Pilosidinium. However, we deem the Early Cretaceous to Miocene genera Batiacasphaera, Kallosphaeridium and Pentafidia are deemed to be separate from Sentusidinium. We refine the definition of the Early Cretaceous to Miocene genus Batiacasphaera to circumscribe cysts with a reticulate to rugulate autophragm and an apical archaeopyle with a free operculum. By contrast, Kallosphaeridium has a ventrally attached apical archaeopyle with five plates that can be interpreted as type (4A1I)@ or type (5A)@; it also has a small operculum relative to the overall cyst diameter. The six accepted Kallosphaeridium species are confined to the Palaeogene. The Australian genus Pentafidia is unusual in appearing to only have five precingular plates; this comprises two species from the Jurassic–Cretaceous transition of Western Australia. Therefore, we emend Sentusidinium to restrict it to acavate, proximate or proximochorate dinoflagellate cysts with an autophragm devoid of, or covered with, highly variable, non-linear ornamentation and a type (tA) apical archaeopyle. Occasionally the elements of ornamentation may be connected, but rarely is a cingulum indicated, and the tabulation is never clearly evident. A kalyptra may be occasionally present. The operculum is free. Following a comprehensive literature review, we accept 17 species in Batiacasphaera. In Kallosphaeridium we accept six species confidently and consider six species to be problematical. We list 38 (34 accepted and four problematical) species of Sentusidinium. Kallosphaeridium? helbyi is here transferred to Cyclonephelium without question. The species Batiacasphaera angularis is occasionally tabulate and hence we transfer it, with question, to Meiourgonyaulax. The Sentusidinium complex is clearly polyphyletic, and all genera considered herein belong to the order Gonyaulacales. Batiacasphaera, Kallosphaeridium and Pentafidia cannot be confidently assigned to a family, whereas Sentusidinium belongs to the Gonyaulacaceae. The number of species within the complex has been reduced from 137 to 68; furthermore, all infraspecific taxa have been eliminated
Trajectories of Quality of Life after Hematopoietic Cell Transplantation: Secondary Analysis of BMT CTN 0902 Data
Quality of life is increasingly recognized as an important secondary endpoint of hematopoietic cell transplantation (HCT). The current study examined the extent to which attrition results in biased estimates of patient quality of life. The study also examined whether patients differ in terms of trajectories of quality of life in the first six months post-transplant. A secondary data analysis was conducted of 701 participants who enrolled in the Blood and Marrow Transplantation Clinical Trials Network (BMT CTN) 0902 trial. Participants completed the SF-36, a measure of quality of life, prior to transplant and 100 and 180 days post-transplant. Results indicated that attrition resulted in slightly biased overestimates of quality of life but the amount of overestimation remained stable over time. Patients could be grouped into three distinct classes based on physical quality of life: 1) low and stable; 2) average and declining, then stable; and 3) average and stable. Four classes of patients emerged for mental quality of life: 1) low and stable; 2) average, improving, then stable; 3) higher than average (by almost 1 SD) and stable; and 4) average and stable. Taken together, these data provide a more comprehensive understanding of quality of life that can be used to educate HCT recipients and their caregivers
The Feasibility of a Behavioral Group Intervention after Weight-loss Surgery: A Randomized Pilot Trial
BACKGROUND: Formal psychosocial support programs after weight-loss surgery are limited in scope and availability.
OBJECTIVE: This randomized pilot study evaluated the feasibility of a postoperative behavioral intervention program.
MATERIALS AND METHODS: Postoperative weight-loss surgery patients (N = 50) were recruited from February 2017-July 2017 and randomized to a four-month behavioral program or usual care wait-list. Outcomes evaluated in addition to feasibility included health-related quality of life (Short Form -36), psychosocial functioning and adherence. Secondary outcomes included within-group changes for each outcome.
RESULTS: Out of eight possible sessions, intervention participants attended a mean of 4.2 sessions. Intervention group participants experienced greater improvements in the social functioning domain of health-related quality of life compared to usual care. Self-reported dietary adherence in the intervention group remained stable, while usual care group dietary adherence declined. Within the intervention group, participants also reported gains in the physical function, pain and general health aspects of quality life from baseline to post-treatment. No differences in weight, mood or other eating behaviors (e.g., loss of control, emotional eating) were evident between groups.
CONCLUSION: Though participation in a postoperative behavioral intervention varied, the program helped participants to maintain aspects of quality of life and self-reported adherence to dietary recommendations.
TRIAL REGISTRATION: ClinicalTrials.gov NCT03092479
Recommended from our members
Neuropsychological Assessment, Neuroimaging, and Neuropsychiatric Evaluation in Pediatric and Adult Patients with Sickle Cell Disease (SCD)
Traditionally, neuropsychological deficits due to Sickle Cell Disease (SCD) have been understudied in adults. We have begun to suspect, however, that symptomatic and asymptomatic Cerebrovascular Events (CVE) may account for an alarming number of deficits in this population. In the current brief review, we critically evaluated the pediatric and adult literatures on the neurocognitive effects of SCD. We highlighted the studies that have been published on this topic and posit that early detection of CVE via neurocognitive testing, neuropsychiatric evaluations, and neuroimaging may significantly reduce adult cognitive and functional morbidities
Single-cell analysis of human glioma and immune cells identifies S100A4 as an immunotherapy target.
A major rate-limiting step in developing more effective immunotherapies for GBM is our inadequate understanding of the cellular complexity and the molecular heterogeneity of immune infiltrates in gliomas. Here, we report an integrated analysis of 201,986 human glioma, immune, and other stromal cells at the single cell level. In doing so, we discover extensive spatial and molecular heterogeneity in immune infiltrates. We identify molecular signatures for nine distinct myeloid cell subtypes, of which five are independent prognostic indicators of glioma patient survival. Furthermore, we identify S100A4 as a regulator of immune suppressive T and myeloid cells in GBM and demonstrate that deleting S100a4 in non-cancer cells is sufficient to reprogram the immune landscape and significantly improve survival. This study provides insights into spatial, molecular, and functional heterogeneity of glioma and glioma-associated immune cells and demonstrates the utility of this dataset for discovering therapeutic targets for this poorly immunogenic cancer
The Sloan Digital Sky Survey-II Supernova Survey: Search Algorithm and Follow-up Observations
The Sloan Digital Sky Survey-II Supernova Survey has identified a large
number of new transient sources in a 300 sq. deg. region along the celestial
equator during its first two seasons of a three-season campaign. Multi-band
(ugriz) light curves were measured for most of the sources, which include solar
system objects, Galactic variable stars, active galactic nuclei, supernovae
(SNe), and other astronomical transients. The imaging survey is augmented by an
extensive spectroscopic follow-up program to identify SNe, measure their
redshifts, and study the physical conditions of the explosions and their
environment through spectroscopic diagnostics. During the survey, light curves
are rapidly evaluated to provide an initial photometric type of the SNe, and a
selected sample of sources are targeted for spectroscopic observations. In the
first two seasons, 476 sources were selected for spectroscopic observations, of
which 403 were identified as SNe. For the Type Ia SNe, the main driver for the
Survey, our photometric typing and targeting efficiency is 90%. Only 6% of the
photometric SN Ia candidates were spectroscopically classified as non-SN Ia
instead, and the remaining 4% resulted in low signal-to-noise, unclassified
spectra. This paper describes the search algorithm and the software, and the
real-time processing of the SDSS imaging data. We also present the details of
the supernova candidate selection procedures and strategies for follow-up
spectroscopic and imaging observations of the discovered sources.Comment: Accepted for publication in The Astronomical Journal (66 pages, 13
figures); typos correcte
A Randomized Phase II Crossover Study of Imatinib or Rituximab for Cutaneous Sclerosis after Hematopoietic Cell Transplantation
Cutaneous sclerosis (CS) occurs in 20% of patients with chronic graft-versus-host disease (GVHD) and can compromise mobility and quality of life
Intestinal Colonization Traits of Pandemic Multidrug-Resistant Escherichia coli ST131
Background. Epidemiological studies point to the gut as a key reservoir of multidrug resistant Escherichia coli multilocus sequence type 131 (ST131), a globally dominant pathogenic clone causing urinary tract and bloodstream infections. Here we report a detailed investigation of its intestinal lifestyle. Methods. Clinical ST131 isolates and type 1 fimbriae null mutants were assessed for colonization of human intestinal epithelia and in mouse intestinal colonization models. Mouse gut tissue underwent histologic analysis for pathology and ST131 localization. Key findings were corroborated in mucus-producing human cell lines and intestinal biopsy specimens. Results. ST131 strains adhered to and invaded human intestinal epithelial cells more than probiotic and commensal strains. The reference ST131 strain EC958 established persistent intestinal colonization in mice, and expression of type 1 fimbriae mediated higher colonization levels. Bacterial loads were highest in the distal parts of the mouse intestine and did not cause any obvious pathology. Further analysis revealed that EC958 could bind to both mucus and underlying human intestinal epithelia. Conclusions. ST131 strains can efficiently colonize the mammalian gut and persist long term. Type 1 fimbriae enhance ST131 intestinal colonization, suggesting that mannosides, currently developed as therapeutics for bladder infections and Crohn’s disease, could also be used to limit intestinal ST131 reservoirs
The Baryon Oscillation Spectroscopic Survey of SDSS-III
The Baryon Oscillation Spectroscopic Survey (BOSS) is designed to measure the
scale of baryon acoustic oscillations (BAO) in the clustering of matter over a
larger volume than the combined efforts of all previous spectroscopic surveys
of large scale structure. BOSS uses 1.5 million luminous galaxies as faint as
i=19.9 over 10,000 square degrees to measure BAO to redshifts z<0.7.
Observations of neutral hydrogen in the Lyman alpha forest in more than 150,000
quasar spectra (g<22) will constrain BAO over the redshift range 2.15<z<3.5.
Early results from BOSS include the first detection of the large-scale
three-dimensional clustering of the Lyman alpha forest and a strong detection
from the Data Release 9 data set of the BAO in the clustering of massive
galaxies at an effective redshift z = 0.57. We project that BOSS will yield
measurements of the angular diameter distance D_A to an accuracy of 1.0% at
redshifts z=0.3 and z=0.57 and measurements of H(z) to 1.8% and 1.7% at the
same redshifts. Forecasts for Lyman alpha forest constraints predict a
measurement of an overall dilation factor that scales the highly degenerate
D_A(z) and H^{-1}(z) parameters to an accuracy of 1.9% at z~2.5 when the survey
is complete. Here, we provide an overview of the selection of spectroscopic
targets, planning of observations, and analysis of data and data quality of
BOSS.Comment: 49 pages, 16 figures, accepted by A
- …