Modelling Radiatively Active Water Ice Clouds in the Martian Water Cycle

The aim of this project is to model the Martian water cycle, including radiatively active water ice clouds, to interpret new observations from Mars Climate Sounder. We will be using the latest version of the LMD MGCM, which includes the new LMD physics routines. A unique data assimilation system will be used to obtain a complete, dynamically self-consistent reconstruction of the entire global circulation for the complete period of the MCS mission to date. From the produced records, a series of diagnostic studies will then be made to characterise the climatology and synoptic meteorology of Mars over seasonal and interannual timescales, including detailed case studies of events such as the formation of cyclonic weather systems. The assimilation results can be used to test the validity of the new cloud schemes introduced to the model, which will improve our understanding of the Martian water cycle

Three-Body Forces Produced by a Similarity Renormalization Group Transformation in a Simple Model

A simple class of unitary renormalization group transformations that force hamiltonians towards a band-diagonal form produce few-body interactions in which low- and high-energy states are decoupled, which can greatly simplify many-body calculations. One such transformation has been applied to phenomenological and effective field theory nucleon-nucleon interactions with success, but further progress requires consistent treatment of at least the three-nucleon interaction. In this paper we demonstrate in an extremely simple model how these renormalization group transformations consistently evolve two- and three-body interactions towards band-diagonal form, and introduce a diagrammatic approach that generalizes to the realistic nuclear problem.Comment: 25 pages, 18 figures, minor typos corrected and references update

Northward field excursions in Saturn’s magnetotail and their relationship to magnetospheric periodicities

We present results from an investigation of Cassini encounters with Saturn’s magnetotail current sheet, using magnetic field and plasma data. In the first of two intervals shown, small periodic changes in the north-south component of the magnetic field are matched by periodic density enhancements associated with the plasma sheet center. In the second interval, a large plasmoid signature is observed set against a background of small-scale current sheet motions. We interpret the quasi-periodic small field deflections and density enhancements as large-scale wave-like motion of the current sheet. We stress that plasmoid signatures are of a clearly different character and occur much less frequently

Precise numerical results for limit cycles in the quantum three-body problem

The study of the three-body problem with short-range attractive two-body forces has a rich history going back to the 1930's. Recent applications of effective field theory methods to atomic and nuclear physics have produced a much improved understanding of this problem, and we elucidate some of the issues using renormalization group ideas applied to precise nonperturbative calculations. These calculations provide 11-12 digits of precision for the binding energies in the infinite cutoff limit. The method starts with this limit as an approximation to an effective theory and allows cutoff dependence to be systematically computed as an expansion in powers of inverse cutoffs and logarithms of the cutoff. Renormalization of three-body bound states requires a short range three-body interaction, with a coupling that is governed by a precisely mapped limit cycle of the renormalization group. Additional three-body irrelevant interactions must be determined to control subleading dependence on the cutoff and this control is essential for an effective field theory since the continuum limit is not likely to match physical systems ({\it e.g.}, few-nucleon bound and scattering states at low energy). Leading order calculations precise to 11-12 digits allow clear identification of subleading corrections, but these corrections have not been computed.Comment: 37 pages, 8 figures, LaTeX, uses graphic

Ecological and evolutionary processes at expanding range margins

Many animals are regarded as relatively sedentary and specialized in marginal parts of their geographical distributions. They are expected to be slow at colonizing new habitats. Despite this, the cool margins of many species' distributions have expanded rapidly in association with recent climate warming. We examined four insect species that have expanded their geographical ranges in Britain over the past 20 years. Here we report that two butterfly species have increased the variety of habitat types that they can colonize, and that two bush cricket species show increased fractions of longer-winged (dispersive) individuals in recently founded populations. Both ecological and evolutionary processes are probably responsible for these changes. Increased habitat breadth and dispersal tendencies have resulted in about 3- to 15-fold increases in expansion rates, allowing these insects to cross habitat disjunctions that would have represented major or complete barriers to dispersal before the expansions started. The emergence of dispersive phenotypes will increase the speed at which species invade new environments, and probably underlies the responses of many species to both past and future climate change

Estimation of badger abundance using faecal DNA typing

1.Wildlife management and conservation programmes often require accurate information on population density, but this can be difficult to obtain, particularly when the species in question is nocturnal or cryptic. Badger populations in Britain are of intense management interest because they are a wildlife reservoir host of bovine tuberculosis (TB). Attempts to manage this infection in badgers, whether by population control or vaccination, require reliable methods of estimating population size. In addition, such estimates are also required to support research into badger ecology and TB epidemiology. Currently, the most accurate estimates of local badger population size are obtained from labour-intensive and time-consuming mark–recapture studies. 2. In recent years, DNA has been successfully extracted from the faeces of certain mammals, and used to generate a genetic profile of the defecating individual. Here we report on an application of this technology to estimate badger abundance.3.Faecal samples were collected on 10 consecutive days from every freshly deposited dropping at latrine sites close to occupied setts in three badger social groups. Badger DNA was extracted from 89% of samples, and 20 different individuals were reliably identified. The genotypes derived from the faecal samples were compared with those obtained from blood or samples from badgers live trapped at the same setts.4.The faecal genotypes from badgers with known trap histories revealed that latrines were used equally by males and females, and by badgers ranging in age from cubs(< 1 year old) to 9 years old. Individual badgers used the latrines on between one and six different nights. Rarefaction analysis produced abundance estimates that closely matched those obtained from live trapping. 5.Synthesis and applications. Systematic sampling and genetic typing of fresh faeces from badger latrines can provide data that can be used to estimate abundance accurately.This approach requires considerably less human resources than repeated live trapping and mark–recapture. The technique may be valuable for future badger research and management in relation to bovine TB, where accurate estimates of abundance at a local scale are required

The effect of metapopulation processes on the spatial scale of adaptation across an environmental gradient

We show that the butterfly Aricia agestis (Lycaenidae) is adapted to its thermal environment in via integer changes in the numbers of generations per year (voltinism): it has two generations per year in warm habitats and one generation per year in cool habitats in north Wales (UK). Voltinism is an “adaptive peak” since individuals having an intermediate number of generations per year would fail to survive the winter, and indeed no populations showed both voltinism types in nature. In spite of this general pattern, 11% of populations apparently possess the “wrong” voltinism for their local environment, and population densities were lower in thermally intermediate habitat patches. Population dynamic data and patterns of genetic differentiation suggest that adaptation occurs at the metapopulation level, with local populations possessing the voltinism type appropriate for the commonest habitat type within each population network. When populations and groups of populations go extinct, they tend to be replaced by colonists from the commonest thermal environment nearby, even if this is the locally incorrect adaptation. Our results illustrate how stochastic population turnover can impose a limit on local adaptation over distances many times larger than predicted on the basis of normal dispersal movements

Efficacy of eribulin in breast cancer: a short report on the emerging new data

Eribulin is a novel microtubule-targeting agent that is approved for the treatment of patients with locally advanced or metastatic breast cancer who have previously received treatment with an anthracycline and a taxane in either the adjuvant or metastatic setting. Eribulin induces mitotic catastrophe leading to cell death but has other important antitumor effects, including reversal of epithelial–mesenchymal transition and remodeling of the tumor vasculature. Eribulin was licensed for the treatment of advanced breast cancer based on results from two large randomized Phase III clinical trials. Current clinical trials of eribulin for breast cancer are evaluating response to treatment earlier in the patient pathway and in combination with other therapeutic agents. This review provides a short overview of emerging new data on the mode of action of eribulin in breast cancer

Sodium Atoms in the Lunar Exotail: Observed Velocity and Spatial Distributions

The lunar sodium tail extends long distances due to radiation pressure on sodium atoms in the lunar exosphere. Our earlier observations measured the average radial velocity of sodium atoms moving down the lunar tail beyond Earth (i.e., near the anti-lunar point) to be ~ 12.5 km/s. Here we use the Wisconsin H-alpha Mapper to obtain the first kinematically resolved maps of the intensity and velocity distribution of this emission over a 15 x 15 deg region on the sky near the anti-lunar point. We present both spatially and spectrally resolved observations obtained over four nights bracketing new Moon in October 2007. The spatial distribution of the sodium atoms is elongated along the ecliptic with the location of the peak intensity drifting 3 deg east along the ecliptic per night. Preliminary modeling results suggest the spatial and velocity distributions in the sodium exotail are sensitive to the near surface lunar sodium velocity distribution. Future observations of this sort along with detailed modeling offer new opportunities to describe the time history of lunar surface sputtering over several days

Penetration of human skin by the cercariae of Schistosoma mansoni : an investigation of the effect of multiple cercarial applications

It has previously been postulated that L-arginine emitted by penetrating Schistosoma mansoni cercariae serves as an intraspecific signal guiding other cercariae to the penetration site. It was suggested that penetrating in groups offers a selective advantage. If this hypothesis is correct and group penetration at one site on the host offers an advantage, it would follow that at such a site, successive groups of cercariae would be able to penetrate skin in either greater numbers or at a faster rate. This prediction was tested by the use of an in vitro model of cercarial penetration based on the Franz cell and using human skin. It was demonstrated that there was no increase in the percentage of cercariae able to penetrate the skin with subsequent exposures. Consequently, it seems unlikely that the release of L-arginine by cercariae during penetration could have evolved as a specific orientation system based on a selective advantage offered by group penetration.Peer reviewe