1,259 research outputs found
An Alternative Approach to the Calculation and Analysis of Connectivity in the World City Network
Empirical research on world cities often draws on Taylor's (2001) notion of
an 'interlocking network model', in which office networks of globalized service
firms are assumed to shape the spatialities of urban networks. In spite of its
many merits, this approach is limited because the resultant adjacency matrices
are not really fit for network-analytic calculations. We therefore propose a
fresh analytical approach using a primary linkage algorithm that produces a
one-mode directed graph based on Taylor's two-mode city/firm network data. The
procedure has the advantage of creating less dense networks when compared to
the interlocking network model, while nonetheless retaining the network
structure apparent in the initial dataset. We randomize the empirical network
with a bootstrapping simulation approach, and compare the simulated parameters
of this null-model with our empirical network parameter (i.e. betweenness
centrality). We find that our approach produces results that are comparable to
those of the standard interlocking network model. However, because our approach
is based on an actual graph representation and network analysis, we are able to
assess cities' position in the network at large. For instance, we find that
cities such as Tokyo, Sydney, Melbourne, Almaty and Karachi hold more strategic
and valuable positions than suggested in the interlocking networks as they play
a bridging role in connecting cities across regions. In general, we argue that
our graph representation allows for further and deeper analysis of the original
data, further extending world city network research into a theory-based
empirical research approach.Comment: 18 pages, 9 figures, 2 table
Increased stimulatory capacity of antigen presenting cells at the site of autoimmune inflammation interferes with regulatory T cell function
Brain oscillatory activity as a biomarker of motor recovery in chronic stroke
In the present work, we investigated the relationship of oscillatory sensorimotor brain activity to motor recovery. The neurophysiological data of 30 chronic stroke patients with severe upperâlimb paralysis are the basis of the observational study presented here. These patients underwent an intervention including movement training based on combined brainâmachine interfaces and physiotherapy of several weeks recorded in a doubleâblinded randomized clinical trial. We analyzed the alpha oscillations over the motor cortex of 22 of these patients employing multilevel linear predictive modeling. We identified a significant correlation between the evolution of the alpha desynchronization during rehabilitative intervention and clinical improvement. Moreover, we observed that the initial alpha desynchronization conditions its modulation during intervention: Patients showing a strong alpha desynchronization at the beginning of the training improved if they increased their alpha desynchronization. Patients showing a small alpha desynchronization at initial training stages improved if they decreased it further on both hemispheres. In all patients, a progressive shift of desynchronization toward the ipsilesional hemisphere correlates significantly with clinical improvement regardless of lesion location. The results indicate that initial alpha desynchronization might be key for stratification of patients undergoing BMI interventions and that its interhemispheric balance plays an important role in motor recovery.Bundesministerium fĂŒr Bildung und Forschung, Grant/Award Numbers: 13GW0053, 16SV7754; Deutsche Forschungsgemeinschaft; Deutscher Akademischer Austauschdienst, Grant/Award Number: 9156335
Alcohol Contributes to Attraction of <em class="EmphasisTypeItalic">Heliothis (= Chloridea) virescens</em> Males to Females
Interactive computation and visualization of structural connectomes in real-time
Structural networks contain high dimensional data that raise huge computational and visualization problems, especially when attempting to characterise them using graph theory. As a result, it can be non-intuitive to grasp the contribution of each edge within a graph, both at a local and global scale. Here, we introduce a new platform that enables tractography-based networks to be explored in a highly interactive real-time fashion. The framework allows one to interactively tune graph-related parameters on the fly, as opposed to conventional visualization softwares that rely on pre-computed connectivity matrices. From a neurosurgical perspective, the method also provides enhanced understanding regarding the potential removal of a specific node or transection of an edge from the network, allowing surgeons and clinicians to discern the value of each node
Opportunities and challenges for data physicalization
Physical representations of data have existed for thousands of years. Yet it is now that advances in digital fabrication, actuated tangible interfaces, and shape-changing displays are spurring an emerging area of research that we call Data Physicalization. It aims to help people explore, understand, and communicate data using computer-supported physical data representations. We call these representations physicalizations, analogously to visualizations -- their purely visual counterpart. In this article, we go beyond the focused research questions addressed so far by delineating the research area, synthesizing its open challenges and laying out a research agenda
A Tonnetz Model for pentachords
This article deals with the construction of surfaces that are suitable for
representing pentachords or 5-pitch segments that are in the same class.
It is a generalization of the well known \"Ottingen-Riemann torus for triads of
neo-Riemannian theories. Two pentachords are near if they differ by a
particular set of contextual inversions and the whole contextual group of
inversions produces a Tiling (Tessellation) by pentagons on the surfaces. A
description of the surfaces as coverings of a particular Tiling is given in the
twelve-tone enharmonic scale case.Comment: 27 pages, 12 figure
A transcriptomic, metabolomic and cellular approach to the physiological adaptation of tomato fruit to high temperature
Dutch and German 3-year-oldsâ representations of voicing alternations
The voicing contrast is neutralised syllable and word finally in Dutch and German, leading to alternations within the morphological paradigm (e.g. Dutch âbed(s)â, be[t] be[d]en, German âdog(s)â, Hun[t]-Hun[d]e). Despite structural similarity, language-specific morphological, phonological and lexical properties impact on the distribution of this alternation in the two languages. Previous acquisition research has focused on one language only, predominantly focusing on childrenâs production accuracy, concluding that alternations are not acquired until late in the acquisition process in either language. This paper adapts a perceptual method to investigate how voicing alternations are represented in the mental lexicon of Dutch and German 3-year-olds. Sensitivity to mispronunciations of voicing word-medially in plural forms was measured using a visual fixation procedure. Dutch children exhibited evidence of overgeneralising the voicing alternation, whereas German children consistently preferred the correct pronunciation to mispronunciations. Results indicate that the acquisition of voicing alternations is influenced by language-specific factors beyond the alternation itself
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