The diet of the Malham Tarn otters: understanding the impacts of a native predator

Otter (Lutra lutra) populations have been recovering in the UK and expanding into new and often isolated habitats. Otters were first sighted at Malham Tarn in 2009, and have since been observed on a regular basis. This study looks at the diet of the Malham Tarn otters and considers their possible impact on prey populations, such as fish, wading birds and white-clawed crayfish

Pollution, health, and the moderating role of physical activity opportunities

Cunningham GB, Wicker P, McCullough BP. Pollution, health, and the moderating role of physical activity opportunities. International Journal of Environmental Research and Public Health. 2020;17(17): 6272.Air and water pollution have detrimental effects on health, while physical activity opportunities have a positive relationship. The purpose of this study was to explore whether physical activity opportunities moderate the relationships among air and water pollution, and measures of health. Aggregate data were collected at the county level in the United States (n = 3104). Variables included the mean daily density of fine particle matter (air pollution), reported cases of health-related drinking water violations (water pollution), subjective ratings of poor or fair health (overall health), the number of physically and mentally unhealthy (physical and mental health, respectively), and the percentage of people living in close proximity to a park or recreation facility (access to physical activity). Air and water pollution have a significant positive effect on all measures of residents' poor health, while physical activity opportunities only have a negative effect on overall health and physical health. Access to physical activity only moderates the relationship between air pollution and all health outcomes. Since physical activity behavior can be more rapidly changed than some causes of pollution, providing the resident population with better access to physical activity can represent an effective tool in environmental health policy

Minimizing Detection Probability Routing in Ad Hoc Networks Using Directional Antennas

In a hostile environment, it is important for a transmitter to make its wireless transmission invisible to adversaries because an adversary can detect the transmitter if the received power at its antennas is strong enough. This paper defines a detection probability model to compute the level of a transmitter being detected by a detection system at arbitrary location around the transmitter. Our study proves that the probability of detecting a directional antenna is much lower than that of detecting an omnidirectional antenna if both the directional and omnidirectional antennas provide the same Effective Isotropic Radiated Power (EIRP) in the direction of the receiver. We propose a Minimizing Detection Probability (MinDP) routing algorithm to find a secure routing path in ad hoc networks where nodes employ directional antennas to transmit data to decrease the probability of being detected by adversaries. Our study shows that the MinDP routing algorithm can reduce the total detection probability of deliveries from the source to the destination by over 74%.RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are

BITC Sensitizes Pancreatic Adenocarcinomas to TRAIL-Induced Apoptosis

Pancreatic adenocarcinoma is an aggressive cancer with a greater than 95% mortality rate and short survival after diagnosis. Chemotherapeutic resistance hinders successful treatment. This resistance is often associated with mutations in codon 12 of the K-Ras gene (K-Ras 12), which is present in over 90% of all pancreatic adenocarcinomas. Codon 12 mutations maintain Ras in a constitutively active state leading to continuous cellular proliferation. Our study determined if TRAIL resistance in pancreatic adenocarcinomas with K-Ras 12 mutations could be overcome by first sensitizing the cells with Benzyl isothiocyanate (BITC). BITC is a component of cruciferous vegetables and a cell cycle inhibitor. BxPC3, MiaPaCa2 and Panc-1 human pancreatic adenocarcinoma cell lines were examined for TRAIL resistance. Our studies show BITC induced TRAIL sensitization by dual activation of both the extrinsic and intrinsic apoptotic pathways

A Comparison of Print and Cursive Handwriting in Fifth and Sixth Grade Students: A Pilot Study

Background: Handwriting is an important skill to master because handwriting demands take up a significant portion of the school day. Pediatric occupational therapists evaluate and treat children who are experiencing challenges with handwriting; therefore, it is important for practitioners to understand the performance of children using both of these writing styles. Method: A convenience sample of 36 fifth and sixth grade students participated in the study. Print and cursive handwriting samples were collected on two separate occasions, and a Wilcoxon-Mann-Whitney test was used to examine speed and legibility differences in these writing styles. Results: Speed in print writing did not differ significantly for gender between the fifth and sixth graders. Cursive writing speed improved significantly for the sixth grade female students compared to the fifth grade female students. Female print legibility scores decreased from the fifth to the sixth grade. Regardless of grade level, the female students were faster with cursive than the male students. Conclusion: The female students consistently used cursive, and their writing speed increased from one year to the next, as compared to the male students, who did not use a consistent writing style. It is important for occupational therapists to educate teachers and parents on the importance of consistent handwriting instruction and practice

How Blue Can You Get? B.B. King, Planetary Humanism and the Blues behind Bars

This article honours the memory of blues musician B.B. King, who died on 14 May 2015, through focusing on his performances in prisons. The article situates his concerts inside Cook County jail and Sing Sing within the wider political crisis during the 1970s surrounding issues of race and class in the American prison system. It suggests the historical resonance of these events can be interpreted through using Paul Gilroy’s notion of planetary humanism. The tone of B.B. King’s guitar carries both the historical trace of African American experience while at the same time voicing a humanistic sensibility beyond the brutalities of racism and incarceration

Orienting of attention via observed eye-gaze is head-centred

Observing averted eye gaze results in the automatic allocation of attention to the gazed-at location. The role of the orientation of the face that produces the gaze cue was investigated. The eyes in the face could look left or right in a head-centred frame, but the face itself could be oriented 90 degrees clockwise or anticlockwise such that the eyes were gazing up or down. Significant cueing effects to targets presented to the left or right of the screen were found in these head orientation conditions. This suggests that attention was directed to the side to which the eyes would have been looking towards, had the face been presented upright. This finding provides evidence that head orientation can affect gaze following, even when the head orientation alone is not a social cue. It also shows that the mechanism responsible for the allocation of attention following a gaze cue can be influenced by intrinsic object-based (i.e. head-centred) properties of the task-irrelevant cue

Analysis of CACTA transposases reveals intron loss as major factor influencing their exon/intron structure in monocotyledonous and eudicotyledonous hosts

Background CACTA elements are DNA transposons and are found in numerous organisms. Despite their low activity, several thousand copies can be identified in many genomes. CACTA elements transpose using a 'cut-and-paste' mechanism, which is facilitated by a DDE transposase. DDE transposases from CACTA elements contain, despite their conserved function, different exon numbers among various CACTA families. While earlier studies analyzed the ancestral history of the DDE transposases, no studies have examined exon loss and gain with a view of mechanisms that could drive the changes. Results We analyzed 64 transposases from different CACTA families among monocotyledonous and eudicotyledonous host species. The annotation of the exon/intron boundaries showed a range from one to six exons. A robust multiple sequence alignment of the 64 transposases based on their protein sequences was created and used for phylogenetic analysis, which revealed eight different clades. We observed that the exon numbers in CACTA transposases are not specific for a host genome. We found that ancient CACTA lineages diverged before the divergence of monocotyledons and eudicotyledons. Most exon/intron boundaries were found in three distinct regions among all the transposases, grouping 63 conserved intron/exon boundaries. Conclusions We propose a model for the ancestral CACTA transposase gene, which consists of four exons, that predates the divergence of the monocotyledons and eudicotyledons. Based on this model, we propose pathways of intron loss or gain to explain the observed variation in exon numbers. While intron loss appears to have prevailed, a putative case of intron gain was nevertheless observedPeer reviewe