102 research outputs found
Is the responsibilization of the cyber security risk reasonable and judicious?
Cyber criminals appear to be plying their trade without much hindrance. Home computer users are particularly vulnerable to attack by an increasingly sophisticated and globally dispersed hacker group. The smartphone era has exacerbated the situation, offering hackers even more attack surfaces to exploit. It might not be entirely coincidental that cyber crime has mushroomed in parallel with governments pursuing a neoliberalist agenda. This agenda has a strong drive towards individualizing risk i.e. advising citizens how to take care of themselves, and then leaving them to face the consequences if they choose not to follow the advice. In effect, citizens are “responsibilized .” Whereas responsibilization is effective for some risks, the responsibilization of cyber security is, we believe, contributing to the global success of cyber attacks. There is, consequently, a case to be made for governments taking a more active role than the mere provision of advice, which is the case in many countries. We conclude with a concrete proposal for a risk regulation regime that would more effectively mitigate and ameliorate cyber risk
Government of the People, By the People: A Look at Trust in eGovernment
Many factors contribute to the willingness of individual citizens to adopt eGovernment systems for filing taxes online, for voting on the Internet, for online licensing, and other digital processes. The growing interest in eGovernment has brought some attention to the concept of eVoting. Various dimensions of trust, along with usability and system ease-of-use, play key roles in influencing citizen intentions to adopt to eVoting system. The present study indicates that, among other factors, citizens’ perceptions that they share the same values as the individual people who are affiliated with providing eGovernment (and eVoting) services are especially instrumental. This study shows that the perception that the agency is made of “people like me” is associated with increased trust in the agency, which in turn is associated with increased levels of other factors that contribute to the intention to vote electronically over the Internet
Providing Theoretical Foundations: Developing an Integrated Set of Guidelines for Theory Adaptation
Developing and advancing theory in the information systems (IS) discipline requires scholars to use and contribute to theory. While few IS scholars create new theories, many borrow and adapt theories from other disciplines to study a variety of phenomena in the realm of IS. Over time, this practice has raised concerns as to the appropriateness and quality of theories adapted in the discipline. In particular, this practice causes issues when one considers conflicting results from many studies that claim to leverage the same theoretical foundation. We examine the issues surrounding theory adaptation in IS and provide a set of integrated theory adaptation guidelines to help scholars successfully and reliably adapt theory. We illustrate how one might use our guidelines via using Protection Motivation Theory in an organizational information security setting
Nucleon distribution amplitudes from lattice QCD
We calculate low moments of the leading-twist and next-to-leading twist
nucleon distribution amplitudes on the lattice using two flavors of clover
fermions. The results are presented in the MSbar scheme at a scale of 2 GeV and
can be immediately applied in phenomenological studies. We find that the
deviation of the leading-twist nucleon distribution amplitude from its
asymptotic form is less pronounced than sometimes claimed in the literature.Comment: 5 pages, 3 figures, 2 tables. RevTeX style. Normalization for
\lambda_i corrected. Discussion of the results extended. To be published in
PR
Non-perturbative renormalization of three-quark operators
High luminosity accelerators have greatly increased the interest in
semi-exclusive and exclusive reactions involving nucleons. The relevant
theoretical information is contained in the nucleon wavefunction and can be
parametrized by moments of the nucleon distribution amplitudes, which in turn
are linked to matrix elements of local three-quark operators. These can be
calculated from first principles in lattice QCD. Defining an RI-MOM
renormalization scheme, we renormalize three-quark operators corresponding to
low moments non-perturbatively and take special care of the operator mixing.
After performing a scheme matching and a conversion of the renormalization
scale we quote our final results in the MSbar scheme at mu=2 GeV.Comment: 49 pages, 3 figure
Exercise, cognition and Alzheimer’s disease: More is not necessarily better
Regional hypoperfusion, associated with a reduction in cerebral metabolism, is a hallmark of Alzheimer’s disease (AD) and contributes to cognitive decline. Cerebral perfusion and hence cognition can be enhanced by exercise. The present review describes first how the effects of exercise on cerebral perfusion in AD are mediated by nitric oxide (NO) and tissue-type plasminogen activator, the release of which is regulated by NO. A conclusion of clinical relevance is that exercise may not be beneficial for the cognitive functioning of all people with dementia if cardiovascular risk factors are present.
The extent to which cardiovascular risk factors play a role in the selection of older people with dementia in clinical studies will be addressed in the second part of the review in which the effects of exercise on cognition are presented. Only eight relevant studies were found in the literature, emphasizing the paucity of studies in this field. Positive effects of exercise on cognition were reported in seven studies, including two that excluded and two that included patients with cardiovascular risk factors. These findings suggest that cardiovascular risk factors do not necessarily undo the beneficial effects of exercise on cognition in cognitively impaired people. Further research is called for, in view of the limitations of the clinical studies reviewed here.
Measuring Information Processing Speed in Mild Cognitive Impairment: Clinical Versus Research Dichotomy
A substantial body of research evidence is indicative of disproportionately slowed information processing speed in a wide range of multi-trial, computer-based, neuroimaging- and electroencephalography-based reaction time (RT) tests in Alzheimer’s disease and mild cognitive impairment (MCI). However, in what is arguably a dichotomy between research evidence and clinical practice, RT associated with different brain functions is rarely assessed as part of their diagnosis. Indeed, often only the time taken to perform a single, specific task, commonly the Trail making test (TMT), is measured. In clinical practice therefore, there can be a failure to assess adequately the integrity of the rapid, serial information processing and response, necessary for efficient, appropriate, and safe interaction with the environment. We examined whether a typical research-based RT task could at least match the TMT in differentiating amnestic MCI (aMCI) from cognitively healthy aging at group level. As aMCI is a heterogeneous group, typically containing only a proportion of individuals for whom aMCI represents the early stages of dementia, we examined the ability of each test to provide intra-group performance variation. The results indicate that as well as significant slowing in performance of the operations involved in TMT part B (but not part A), individuals with aMCI also experience significant slowing in RT compared to controls. The results also suggest that research-typical RT tests may be superior to the TMT in differentiating between cognitively healthy aging and aMCI at group level and in revealing the performance variability one would expect from an etiologically heterogeneous disorder such as aMCI
An integrated framework for optimizing sculptured surface CNC tool paths based on direct software object evaluation and viral intelligence
Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility
Impaired lung function is often caused by cigarette smoking, making it challenging to disentangle its role in lung cancer susceptibility. Investigation of the shared genetic basis of these phenotypes in the UK Biobank and International Lung Cancer Consortium (29,266 cases, 56,450 controls) shows that lung cancer is genetically correlated with reduced forced expiratory volume in one second (FEV1: r(g) = 0.098, p = 2.3 x 10(-8)) and the ratio of FEV1 to forced vital capacity (FEV1/FVC: r(g) = 0.137, p = 2.0 x 10(-12)). Mendelian randomization analyses demonstrate that reduced FEV1 increases squamous cell carcinoma risk (odds ratio (OR) = 1.51, 95% confidence intervals: 1.21-1.88), while reduced FEV1/FVC increases the risk of adenocarcinoma (OR = 1.17, 1.01-1.35) and lung cancer in never smokers (OR = 1.56, 1.05-2.30). These findings support a causal role of pulmonary impairment in lung cancer etiology. Integrative analyses reveal that pulmonary function instruments, including 73 novel variants, influence lung tissue gene expression and implicate immune-related pathways in mediating the observed effects on lung carcinogenesis
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