226 research outputs found
Chronic graft-versus-host disease and its management in children
AbstractChronic graft-versus-host disease is sometimes a severe, disabling and long-lasting complication of allogeneic hematopoietic stem cell transplantation. Its frequency lies between 10 and 40% of pediatric graft recipients, depending on a number of risk factors. Such factors are the type, i.e. HLA-identical related or not, gender and age of the stem cell transplant donor, original diagnosis of the patient and, most importantly, the occurrence or not of a prior acute graft-verus-host disease. Chronic graft-versus-host disease manifests itself as a collagen vascular autoimmune disease. Its treatment consists of immuno-modulatory and antiinfections drugs, in addition to supportive care and psycho-social support. Medical treatment demands a tailor-made approach and careful and prolonged surveillance
Clinical and immunological studies in patients with an increased serum IgD Level
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Hyperimmunoglobulinemia D and periodic fever : A new syndrome
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Chronic graft-versus-host disease and its management in children
Chronic graft-versus-host disease is sometimes a severe, disabling and long-lasting complication of allogeneic hematopoietic stem cell transplantation. Its frequency lies between 10 and 40% of pediatric graft recipients, depending on a number of risk factors. Such factors are the type, i.e. HLA-identical related or not, gender and age of the stem cell transplant donor, original diagnosis of the patient and, most importantly, the occurrence or not of a prior acute graft-verus-host disease. Chronic graft-versus-host disease manifests itself as a collagen vascular autoimmune disease. Its treatment consists of immuno-modulatory and antiinfections drugs, in addition to supportive care and psycho-social support. Medical treatment demands a tailor-made approach and careful and prolonged surveillance
Transverse spin effects in hadron-pair production from semi-inclusive deep inelastic scattering
First measurements of azimuthal asymmetries in hadron-pair production in
deep-inelastic scattering of muons on transversely polarised ^6LiD (deuteron)
and NH_3 (proton) targets are presented. The data were taken in the years
2002-2004 and 2007 with the COMPASS spectrometer using a muon beam of 160 GeV/c
at the CERN SPS. The asymmetries provide access to the transversity
distribution functions, without involving the Collins effect as in single
hadron production. The sizeable asymmetries measured on the NH_ target indicate
non-vanishing u-quark transversity and two-hadron interference fragmentation
functions. The small asymmetries measured on the ^6LiD target can be
interpreted as indication for a cancellation of u- and d-quark transversities.Comment: 13 pages, 4 figures, updated to the published versio
The Spin-dependent Structure Function of the Proton g_1^p and a Test of the Bjorken Sum Rule
The inclusive double-spin asymmetry, A_1^p, has been measured at COMPASS in
deepinelastic polarised muon scattering off a large polarised NH3 target. The
data, collected in the year 2007, cover the range Q2 > 1 (GeV/c)^2, 0.004 < x <
0.7 and improve the statistical precision of g_1^p(x) by a factor of two in the
region x < 0.02. The new proton asymmetries are combined with those previously
published for the deuteron to extract the non-singlet spin-dependent structure
function g_1^NS(x,Q2). The isovector quark density, Delta_q_3(x,Q2), is
evaluated from a NLO QCD fit of g_1^NS. The first moment of Delta_q3 is in good
agreement with the value predicted by the Bjorken sum rule and corresponds to a
ratio of the axial and vector coupling constants g_A/g_V =
1.28+-0.07(stat)+-0.10(syst).Comment: 12 pages, 5 figure
Measurement of the Collins and Sivers asymmetries on transversely polarised protons
The Collins and Sivers asymmetries for charged hadrons produced in deeply
inelastic scattering on transversely polarised protons have been extracted from
the data collected in 2007 with the CERN SPS muon beam tuned at 160 GeV/c. At
large values of the Bjorken x variable non-zero Collins asymmetries are
observed both for positive and negative hadrons while the Sivers asymmetry for
positive hadrons is slightly positive over almost all the measured x range.
These results nicely support the present theoretical interpretation of these
asymmetries, in terms of leading-twist quark distribution and fragmentation
functions.Comment: 9 Pages, 5 figure
Quark helicity distributions from longitudinal spin asymmetries in muon-proton and muon-deuteron scattering
Double-spin asymmetries for production of charged pions and kaons in
semi-inclusive deep-inelastic muon scattering have been measured by the COMPASS
experiment at CERN. The data, obtained by scattering a 160 GeV muon beam off a
longitudinally polarised NH_3 target, cover a range of the Bjorken variable x
between 0.004 and 0.7. A leading order evaluation of the helicity distributions
for the three lightest quarks and antiquark flavours derived from these
asymmetries and from our previous deuteron data is presented. The resulting
values of the sea quark distributions are small and do not show any sizable
dependence on x in the range of the measurements. No significant difference is
observed between the strange and antistrange helicity distributions, both
compatible with zero. The integrated value of the flavour asymmetry of the
helicity distribution of the light-quark sea, \Delta u-bar - \Delta d-bar, is
found to be slightly positive, about 1.5 standard deviations away from zero.Comment: 13 pages, 5 figure
The COMPASS Experiment at CERN
The COMPASS experiment makes use of the CERN SPS high-intensitymuon and
hadron beams for the investigation of the nucleon spin structure and the
spectroscopy of hadrons. One or more outgoing particles are detected in
coincidence with the incoming muon or hadron. A large polarized target inside a
superconducting solenoid is used for the measurements with the muon beam.
Outgoing particles are detected by a two-stage, large angle and large momentum
range spectrometer. The setup is built using several types of tracking
detectors, according to the expected incident rate, required space resolution
and the solid angle to be covered. Particle identification is achieved using a
RICH counter and both hadron and electromagnetic calorimeters. The setup has
been successfully operated from 2002 onwards using a muon beam. Data with a
hadron beam were also collected in 2004. This article describes the main
features and performances of the spectrometer in 2004; a short summary of the
2006 upgrade is also given.Comment: 84 papes, 74 figure
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