Estudio de la trabeculación ósea en la artrodesis subastragalina

En este artículo presentamos nuestra casuística en artrodesis artroscópica subastragalina revisando los principios biomecánicos que rigen esta articulación y presentando ésta como una técnica válida para el tratamiento de distintas patologías en el retropié que interesan esta articulación.We present our casuistic on arthroscopic subtalar arthrodesis reviewing the biomechanics of this joint and presenting it as a valid technique for the treatment of some pathologies in the rearfoot that affect this joint.Premio al mejor trabajo en el XXXII Congreso de la Sociedad Ibérica de Biomecánica y BiomaterialesPeer ReviewedAward-winnin

Ly-alpha excess in high redshift radio galaxies: a signature of star formation

About 54% of radio galaxies at z>3 and 8% of radio galaxies at 2<z<3 show unusually strong Ly-alpha emission, compared with the general population of high redshift (z>2) radio galaxies. These Ly-alpha excess objects (LAEs) show Ly-alpha/HeII values consistent with or above standard photoionization model predictions. We show that the most successful explanation is the presence of a young stellar population which provides the extra supply of ionizing photons required to explain the Ly-alpha excess in at least the most extreme LAEs (probably in all of them). The measurement of unusually high Ly-alpha ratios in the extended gas of some high redshift radio galaxies suggests that star formation activity occurs in spatial scales of tens of kpc. We argue that, although the fraction of LAEs may be incompletely determined, both at 23, the much larger fraction of LAEs found at z>3 is a genuine redshift evolution and not due to selection effects. Therefore, our results suggest that the radio galaxy phenomenon is more often associated with a massive starburst at z>3 than at z<3.Comment: 14 pages, 5 figures, accepted for publication in MNRA

Virtual reality training platform for flexible ureterorenoscopy interventions with a minimally invasive surgical robot

The total number of ureteroscopy (URS) interventions during the past years has dramatically increased due to the ongoing technological advances and the benefits associated with these techniques. However, the current URS procedure presents some drawbacks to urologic surgeons. The LITHOS project was created with the main objective of developing a surgical robotic system for flexible ureterorenoscopic lithotripsy interventions, offering a technological solution that meets the real needs of both patients and surgeons in this type of procedures. In this paper, a virtual reality environment for flexible ureterorenoscopy interventions is presented. The proposed environment provides a suitable training platform for surgeons manipulating the surgical robotic system

Organic carbon and environmental quality of riverine and off-shore sediments from the Gulf of Cádiz, Spain

6 páginas, 2 figuras, 3 tablas, 14 referencias.-- [email protected] we show that heavy metal geoaccumulation is apparent in the Tinto and Odiel estuary and, at a lower magnitude, in off-shore sediments. Values above probable effects level (PEL) are recorded for As, Cu, Hg, Pb and Zn in the Tinto and Odiel estuary, for As and Hg in the associated off-shore sediments and for As in the Guadiana River. Significant correlations were found between total organic carbon (TOC) and Cr, Cu, Ni and Zn in the Tinto and Odiel estuary, and Cr, Cu, Ni, Pb, Hg and As in the Guadiana River. PCA analysis differentiated the three studied locations.Peer reviewe

Organic carbon and environmental quality of riverine and off-shore sediments from the Gulf of Cádiz, Spain

6 páginas, 2 figuras, 3 tablas, 14 referencias.-- [email protected] we show that heavy metal geoaccumulation is apparent in the Tinto and Odiel estuary and, at a lower magnitude, in off-shore sediments. Values above probable effects level (PEL) are recorded for As, Cu, Hg, Pb and Zn in the Tinto and Odiel estuary, for As and Hg in the associated off-shore sediments and for As in the Guadiana River. Significant correlations were found between total organic carbon (TOC) and Cr, Cu, Ni and Zn in the Tinto and Odiel estuary, and Cr, Cu, Ni, Pb, Hg and As in the Guadiana River. PCA analysis differentiated the three studied locations.Peer reviewe

Hacia una ciudadanía democrática e intercultural. Apuntes para la formación del profesorado

En la actualidad, la construcción de una ciudadanía democrática no se puede comprender al margen de las consideraciones acerca del respeto de la diversidad cultural y de las medidas destinadas a fomentarla; en especial, ante el aumento de discursos y manifestaciones racistas, así como respecto a las sucesivas crisis humanitarias en relación a la inmigración. Ante este panorama, en este artículo proponemos conjugar la educación cívica desde el paradigma intercultural. Para ello, reivindicamos, por un lado, el papel de la escuela como espacio de mediación cultural y de fomento de la convi- vencia; por otro, y de forma complementaria, destacamos el papel del profe- sorado como agente social con amplia implicación en la conformación de ciudadanía democrática. A partir de ahí, indagamos en diferentes estudios que destacan las carencias en muchas de las propuestas de formación del profesorado que se desarrollan desde una óptica intercultural. Acabamos insistiendo en la necesidad de reforzar aquel tipo de formación en clave intercultural que potencia el conocimiento de sí como clave para la actuación educativa.La Revista Publicaciones se edita en la Facultad y cuenta con los siguientes patrocinadores: Consejería de Educación, Juventud y Deportes (Ciudad Autónoma de Melilla) Vicerrectorado de Investigación y Transferencia de la Universidad de Granada Facultad de Educación y Humanidades de Melill

Do the lower body strength assessment tests in the Spanish navy really measure what they purport to measure?

The main objective of this research was to analyse the efficacy of lower body strength assessment tests in the Armed Forces Physical Assessment System. Secondly, it was to determine what relationship exists between the physical evaluation system of the Spanish Armed forces and standardized evaluation protocols (Gold standard). A total of 905 students enrolled in the military/civil bachelor’s degree (813 male and 92 female) participated in this study. The influence of the sex of the participants was studied through the student’s t-test for independent data, and the degree of association between variables was defined by Pearson’s correlation coefficient. The results present moderate correlations (r = 0.67, r = 0.66; p < 0.001) between the vertical jump test used by the Army and the power or elastic force tests commonly used in practice and in research. The results obtained reflect a moderate relationship between the gold standard tests and the tests used by the Army, which suggests that the tests currently used to assess lower body strength should be adapted to more objective measurement tools which would allow a better comparison between samples from different armed forces

Similarities and differences in RANTES and (AOP)-RANTES-triggered signals : implications for chemotaxis

11 páginas, 8 figuras.Chemokines are a family of proinflammatory cytokines that attract and activate specific types of leukocytes. Chemokines mediate their effects via interaction with seven transmembrane G proteinÐcoupled receptors (GPCR). Using CCR5-transfected HEK-293 cells, we show that both the CCR5 ligand, RANTES, as well as its derivative, aminooxypentane (AOP)-RANTES, trigger immediate responses such as Ca2+ influx, receptor dimerization, tyrosine phosphorylation,and Gai as well as JAK/STAT association to the receptor. In contrast to RANTES, (AOP)-RANTES is unable to trigger late responses, as measured by the association of focal adhesion kinase (FAK) to the chemokine receptor complex, impaired cell polarization required for migration, or chemotaxis. The results are discussed in the context of the dissociation of the late signals, provoked by the chemokines required for cell migration, from early signals.Peer reviewe

Hypotonic swelling promotes nitric oxide release in cardiac ventricular myocytes: Impact on swelling-induced negative inotropic effect

Aims Cardiomyocyte swelling occurs in multiple pathological situations and has been associated with contractile dysfunction, cell death, and enhanced propensity to arrhythmias.We investigate whether hypotonic swelling promotes nitric oxide (NO) release in cardiomyocytes, and whether it impacts on swelling-induced contractile dysfunction. Methods and results Superfusing rat cardiomyocytes with a hypotonic solution (HS; 217 mOsm), increased cell volume, reduced myocyte contraction and Ca2+ transient, and increased NO-sensitive 4-amino-5-methylamino-2', 7'-difluorofluorescein diacetate (DAF-FM) fluorescence. When cells were exposed to HS + 2.5 mMof theNOsynthase inhibitor L-NAME, cell swelling occurred in the absence of NOrelease. Swelling-induced NO release was also prevented by the nitric oxide synthase 1 (NOS1) inhibitor, nitroguanidine, and significantly reduced in NOS1 knockout mice. Additionally, colchicine (inhibitor of microtubule polymerization) prevented the increase in DAF-FM fluorescence induced by HS, indicating that microtubule integrity is necessary for swelling-inducedNOrelease. The swelling-induced negative inotropic effectwas exacerbated in the presence of either L-NAME, nitroguandine, the guanylate cyclase inhibitor, ODQ, or the PKG inhibitor, KT5823, suggesting that NOS1-derived NO provides contractile support via a cGMP/PKG-dependent mechanism. Indeed, ODQ reduced Ca2+ wave velocity and both ODQ and KT5823 reduced the HS-induced increment in ryanodine receptor (RyR2, Ser2808) phosphorylation, suggesting that in this context, cGMP/PKG may contribute to preserve contractile function by enhancing sarcoplasmic reticulum Ca2+ release. Conclusions Our findings suggest a novel mechanism for NO release in cardiomyocytes with putative pathophysiological relevance determined, at least in part, by its capability to reduce the extent of contractile dysfunction associated with hypotonic swelling.Centro de Investigaciones Cardiovasculare