Dissimilar occupations and marital stability

We show that information revealed by the occupation choices of spouses predicts marital dissolution. Using a novel measure of occupational distance constructed from the O*Net Content Model, we find that spouses more closely matched in terms of their occupations' requisite knowledge are more likely to divorce. This supports the hypothesis that gains from division of labor within a household can render a marriage more durable. On the other hand, spouses that are dissimilar in terms of their occupations' activities are more likely to divorce. This suggests that each spouse brings an inclination toward certain activities to the marriage that reflects compatible preferences for joint consumption of household public goods

CSF GABA is reduced in first-episode psychosis and associates to symptom severity

Schizophrenia is characterized by a multiplicity of symptoms arising from almost all domains of mental function. γ-Aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the brain and is increasingly recognized to have a significant role in the pathophysiology of the disorder. In the present study, cerebrospinal fluid (CSF) concentrations of GABA were analyzed in 41 first-episode psychosis (FEP) patients and 21 age- and sex-matched healthy volunteers by high-performance liquid chromatography. We found lower CSF GABA concentration in FEP patients compared with that in the healthy volunteers, a condition that was unrelated to antipsychotic and/or anxiolytic medication. Moreover, lower CSF GABA levels were associated with total and general score of Positive and Negative Syndrome Scale, illness severity and probably with a poor performance in a test of attention. This study offers clinical in vivo evidence for a potential role of GABA in early-stage schizophrenia