Frecuencia de Maloclusión Dental en Escolares y su Relación con la Edad, el Sexo y la Escuela de Procedencia

Objetivo: Evaluar la frecuencia y distribución de maloclusión dental y su asociación con la edad, sexo y escuela de procedencia. Material y Métodos. Se llevó a cabo un estudio epidemiológico de carácter descriptivo, transversal y prolectivo, en el cual fueron examinados 399 escolares entre ocho y once años previa autorización de sus padres. La calibración del examinador se realizó para minimizar la variabilidad intra examinador y se observó un coeficiente de kappa de 0,997 para la valoración del tipo de oclusión de acuerdo a los criterios de Angle, Dewey y Anderson, valor que refleja un alto grado de confiabilidad. Resultados. El 75.7% mostró algún tipo de maloclusión dental, no mostrando asociación alguna con la edad, el sexo o la escuela de procedencia. La Clase I de acuerdo con Dewey-Anderson los tipos 1 y 2 fueron los más presentes. Conclusión. Se observó la posibilidad de que el nivel educativo sobre la maloclusión dental sea un factor más determinante en comparación con el poder adquisitivo de las familias de los niños, como factor de riesgo para desarrollar cualquier tipo de maloclusión dental. Objective: This paper focuses on evaluating the frequency and distribution of dental malocclusion and its association with age, sex, and school of origin. Material and Methods: A cross-sectional study was carried out on a sample of 399 schoolchildren between eight and eleven years old, and they were examined with the prior authorization of their parents. The examiner's calibration was performed to minimize intra-examiner variability. A kappa coefficient of 0.997 was observed for the assessment of the type of occlusion according to the criteria of Angle, Dewey and Anderson, which is a value that reflects a high degree of reliability. Results: 75.7% presented some type of dental malocclusion, showing no association with age, sex, or school of origin. Class I according to Dewey-Anderson types 1 and 2 were mostly present. Conclusion: In conclusion, it was observed that the educational level on dental malocclusion is a more decisive factor compared to the purchasing power of children's families. This, however, is considered as a risk factor for the development of some type of dental malocclusion

E1 and E2 Viral Proteins as Therapeutic Targets for Development of Antiviral Agents

The importance of studying the human papillomavirus (HPV) is because it is a disease that relies on 14 HPV types classified as carcinogenic high risk and that contributes to cervical cancers affecting approximately 527,600 women yearly and causing 265,387 deaths yearly, being the second mortality cause for women globally. In Mexico, 13.9% of demises are due to cervical uterine cancer (CUCA). The challenges for a vaccine that may prevent HPV occurrence are an active field for scientists with significant advances but still undergoing for a full cure to this disease. In this work, latest research trends to treat HPV are analyzed, and by means of molecular coupling analysis, a modeling and simulation process to predict interactions of leader molecules with the target for synthetic elaboration of a possible therapeutic treatment is developed. One of the main topics discussed in this chapter relates to new drug design for HPV treatment, which is related to the inhibitors of protein-protein interactions and in the protein drugs. Regarding HPV therapy development, a group of small molecules has been identified using high-performance sieving capable of interrupting HPV16 E1-E2 interaction, which helps avoid viral replication. Some of these compounds displayed nanomolar affinities and high specificity

Investigar para educar en una conyuntura de crisis

Esta publicación pretende hacer visible el trabajo de los docentes investigadores de la Facultad de Educación (FED) de la Universidad Nacional de Cuyo, unidad académica que forma a formadores y que investiga para ofrecer respuestas a problemas educativos actuales. Es una recopilación de conocimientos evaluados por pares, quienes, de modo creativo y fundamentado, ofrecen al lector diversas respuestas que predisponen al diálogo, sin presentar sus posturas como verdades absolutas. La Facultad de Educación, como educadora de futuros profesores, acoge asignaturas y profesionales de múltiples áreas, desde la lingüística o la matemática hasta las ciencias naturales y sociales, pasando por muchas otras disciplinas, tales como: antropología, didáctica, pedagogía o ética; así, los docentes-investigadores de la FED realizan estudios muy diversos, lo cual se ve reflejado en los trabajos que se presentan

Ala Este. Revista de Teoría de la Literatura y Literatura Comparada

Ala Este. Revista de Teoría de la Literatura y Literatura Comparada consiste en la consolidación de una revista creada en 2020/2021, de carácter anual, liderada por alumnos y alumnas de la UCM, que siga los estándares de calidad de las revistas científicas (evaluación por pares de ciego, índices de impacto…) y en la que publiquen alumnos y alumnas de la UCM y de otras universidades. Este año se ha seguido trabajando los estándares de calidad que requieren las revistas científicas, se ha realizado un congreso para jóvenes investigadores, El brillo inútil. Experimentación, juventud y creación, del cual se están editando las actas, y se ha lanzado una nueva publicación de carácter anual, Ala Este. Revista de creación literaria, que se publicará a finales de 2023.Depto. de Lengua Española y Teoría de la LiteraturaFac. de FilologíaFALSEsubmitte

IV Foro Internacional de Ganadería Sustentable: conectividad ecosistémica y articulación territorial hacia la Agenda 2030

En este espacio plural de análisis y reflexiones, buscamos articular conceptos y posibilidades para los territorios de montaña del centro de México, dando importancia a medios de vida vinculados a la ganadería y su interacción ecosistémica, fundamentado en innovaciones, casos de éxito e iniciativas emblemáticas nacionales e internacionales. La socialización de experiencias es uno de los pilares para transitar hacia la sostenibilidad de los sistemas productivos ganaderos: compartir logros e iniciativas, crear sinergias e identificar vulnerabilidades desde distintos enfoques.GIZ, Agencia de Cooperación Aleman

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

Nutritional Value and Volatile Compounds of Black Cherry (Prunus serotina) Seeds

Prunus serotina (black cherry), commonly known in Mexico as capulín, is used in Mexican traditional medicine for the treatment of cardiovascular, respiratory, and gastrointestinal diseases. Particularly, P. serotina seeds, consumed in Mexico as snacks, are used for treating cough. In the present study, nutritional and volatile analyses of black cherry seeds were carried out to determine their nutraceutical potential. Proximate analysis indicated that P. serotina raw and toasted seeds contain mostly fat, followed by protein, fiber, carbohydrates, and ash. The potassium content in black cherry raw and toasted seeds is high, and their protein digestibility-corrected amino acid scores suggest that they might represent a complementary source of proteins. Solid phase microextraction and gas chromatography/flame ionization detection/mass spectrometry analysis allowed identification of 59 and 99 volatile compounds in the raw and toasted seeds, respectively. The major volatile compounds identified in raw and toasted seeds were 2,3-butanediol and benzaldehyde, which contribute to the flavor and odor of the toasted seeds. Moreover, it has been previously demonstrated that benzaldehyde possesses a significant vasodilator effect, therefore, the presence of this compound along with oleic, linoleic, and α-eleostearic fatty acids indicate that black cherry seeds consumption might have beneficial effects on the cardiovascular system

Data from: Adsorption and corrosion inhibition behavior of new theophylline-triazole based derivatives for steel in acidic medium

The design and synthesis of a series of theophylline derivatives containing 1,2,3-triazole moieties is presented. The corrosion inhibition activities of these new triazole-theophylline compounds were evaluated by studying the corrosion of API 5L X52 steel in 1 M HCl media. The results showed that an increase in the concentration of the theophylline-triazole derivatives also increases the charge transference resistance (Rct) value, enhancing inhibition efficiency and decreasing the corrosion process. The electrochemical impedance spectroscopy under static conditions studies revealed that the best inhibition efficiencies (~90%) at 50 ppm are presented by the all- substituted compounds. According to the Langmuir isotherm, the compounds 4 and 5 analyzed exhibit physisorption-chemisorption process, with exception of the hydrogen 3, bromo 6 and iodo 7 substituted compound, which exhibit chemisorption process. The corrosion when submerging a steel bar in 1 M HCl was studied using SEM-EDS. This experiment showed that the corrosion process decreases considerably in the presence of 50 ppm of the organic inhibitors. Finally, theoretical study showed a correlation between EHOMO, hardness (η), electrophilicity (W), atomic charge and the inhibition efficiency in which the iodo 7 substituted compound presents the best inhibitor behavior

Experimental and Theoretical Studies on Acid Corrosion Inhibition of API 5L X70 Steel with Novel 1-N-α-d-Glucopyranosyl-1H-1,2,3-Triazole Xanthines

A series of novel 1-N-α-d-glucopyranosyl-1H-1,2,3-triazole xanthines was synthesized from azido sugars (glucose, galactose, and lactose) and propargyl xanthines (theophylline and theobromine) using a typical copper (I)-catalyzed azide–alkyne 1,3-dipolar cycloaddition. The corrosion inhibition activities of these new carbohydrate-xanthine compounds were evaluated by studying the corrosion of API 5 L X70 steel in a 1 M HCl medium. The results showed that, at 10 ppm, a 90% inhibition efficiency was reached by electrochemical impedance spectroscopy. The inhibitory efficiency of these molecules is explained by means of quantum chemical calculations of the protonated species with the solvent effect, which seems to better represent the actual situation of the experimental conditions. Some quantum chemical parameters were analyzed to characterize the inhibition performance of the tested molecules