377 research outputs found
Some problems and prospects of the nephrology center
The problem of supportability of the population with renal replacement therapy is one of the key problems in the modern healthcare system. The quality of medical care in general depends on its solution. In recent years, positive trends have been observed in the activities of the domestic renal replacement therapy service, but these changes are not enough to meet the needs of the population adequately.Проблема обеспеченности населения заместительной почечной терапией является одной из ключевых в современной системе здравоохранения. от ее решения зависит качество оказания медицинской помощи в целом. В деятельности отечественной службы заместительной почечной терапии в последние годы прослеживаются положительные тенденции, однако этих изменений явно недостаточно для адекватного покрытия потребности населения
The use of apolipoprotein A-I as a component of serum-free nutrient medium for bone marrow cell culture
An important step in preparation of cells for cell therapy and tissue engineering is the cultivation of cells in vitro. The aim of this work is to study the effect of human apolipoprotein A-I (apoA-I) on the functional activity of cultured bone marrow cells and to show the possibility of using this protein instead of animal fetal serum. Material and methods. Bone marrow cells were cultured in 24-well plates in RPMI-1640 medium in a CO2 incubator at a temperature of 37 °C. The rate of incorporation of [14C]-leucine into the total cell protein and [3H]-thymidine into the DNA was used as an integral indicator of cell viability during cultivation. Results and discussion. It was found that the rate of DNA synthesis in bone marrow cells in the presence of apo A-I increased compared with the control group (without apo A-I) by 55 % after 8 hours, by 523 % after 24 hours and by 219 % after 48 hours. Under these conditions the rate of protein synthesis was also increased. The results indicate that the presence of apo A-I in serum-free culture medium preserves the functional activity of cultured bone marrow cells. Considering that the regulatory effect of apo A-I is achieved at a low protein concentration in the medium (15 μg/ml), isolation of apo A-I from the patient’s own blood serum will provide a practically safe nutrient medium for culturing autologous bone marrow cells with applications in personalized cell therapy and tissue engineering
Modern problems of teaching human anatomy in medical universities and prospects for their solution
Teaching anatomy in medical schools requires reforming in order to improve the quality of teaching students at the current stage of training qualified doctors.Преподавание анатомии в медицинских вузах требует реформирования с целью улучшения качества обучения студентов на современном этапе подготовки квалифицированных врачей
Ozone therapy with obliterating atherosclerosis of lower limb arteries
Our studies show that ozone therapy is an effective method for correcting hypercoagulability and tissue hypoxia. The use of infusion of ozone therapy in most cases leads to a significant decrease in the size of venous ulcers, or their complete epithelialization, but also leads to a reduction of early postoperative thrombosis when OAANK11 В -111 Art.Наши исследования показывают, что озонотерапия является эффективным методом коррекции гиперкоагуляции и тканевой гипоксии. Применение инфузионной озонотерапии в большинстве случаев приводит к значительному уменьшению размеров трофических язв, или к их полной зпителизации, а также ведёт к уменьшению ранних послеоперационных тромбозов при ОААНК11 Б -111 ст
Evidence for the exclusive decay Bc+- to J/psi pi+- and measurement of the mass of the Bc meson
We report first evidence for a fully reconstructed decay mode of the
B_c^{\pm} meson in the channel B_c^{\pm} \to J/psi \pi^{\pm}, with J/psi \to
mu^+mu^-. The analysis is based on an integrated luminosity of 360 pb$^{-1} in
p\bar{p} collisions at 1.96 TeV center of mass energy collected by the Collider
Detector at Fermilab. We observe 14.6 \pm 4.6 signal events with a background
of 7.1 \pm 0.9 events, and a fit to the J/psi pi^{\pm} mass spectrum yields a
B_c^{\pm} mass of 6285.7 \pm 5.3(stat) \pm 1.2(syst) MeV/c^2. The probability
of a peak of this magnitude occurring by random fluctuation in the search
region is estimated as 0.012%.Comment: 7 pages, 3 figures. Version 3, accepted by PR
Measurement of the Helicity Fractions of W Bosons from Top Quark Decays Using Fully Reconstructed top-antitop Events with CDF II
We present a measurement of the fractions F_0 and F_+ of longitudinally
polarized and right-handed W bosons in top quark decays using data collected
with the CDF II detector. The data set used in the analysis corresponds to an
integrated luminosity of approximately 318 pb -1. We select ttbar candidate
events with one lepton, at least four jets, and missing transverse energy. Our
helicity measurement uses the decay angle theta*, which is defined as the angle
between the momentum of the charged lepton in the W boson rest frame and the W
momentum in the top quark rest frame. The cos(theta*) distribution in the data
is determined by full kinematic reconstruction of the ttbar candidates. We find
F_0 = 0.85 +0.15 -0.22 (stat) +- 0.06 (syst) and F_+ = 0.05 +0.11 -0.05 (stat)
+- 0.03 (syst), which is consistent with the standard model prediction. We set
an upper limit on the fraction of right-handed W bosons of F_+ < 0.26 at the
95% confidence level.Comment: 11 pages, 2 figures, submitted to Phys. Rev.
Measurement of and Production in Collisions at = 1.96 TeV
The Standard Model predictions for and production are
tested using an integrated luminosity of 200 pb of \ppbar collision data
collected at the Collider Detector at Fermilab. The cross sections are measured
selecting leptonic decays of the and bosons, and photons with
transverse energy GeV that are well separated from leptons. The
production cross sections and kinematic distributions for the and
are compared to SM predictions.Comment: 7 pages, 4 figures, submitted to PR
Measurement of the ttbar Production Cross Section in ppbar Collisions at sqrt(s) = 1.96 TeV
We present a measurement of the top quark pair production cross section in
ppbar collisions at sqrt(s)=1.96 TeV using 318 pb^{-1} of data collected with
the Collider Detector at Fermilab. We select ttbar decays into the final states
e nu + jets and mu nu + jets, in which at least one b quark from the t-quark
decays is identified using a secondary vertex-finding algorithm. Assuming a top
quark mass of 178 GeV/c^2, we measure a cross section of 8.7 +-0.9 (stat)
+1.1-0.9 (syst) pb. We also report the first observation of ttbar with
significance greater than 5 sigma in the subsample in which both b quarks are
identified, corresponding to a cross section of 10.1 +1.6-1.4(stat)+2.0-1.3
(syst) pb.Comment: Accepted for publication in Physics Review Letters, 7 page
Top quark mass measurement using the template method at CDF
We present a measurement of the top quark mass in the lepton+jets and
dilepton channels of decays using the template method. The data
sample corresponds to an integrated luminosity of 5.6 fb of
collisions at Tevatron with TeV, collected with the CDF II
detector. The measurement is performed by constructing templates of three
kinematic variables in the lepton+jets and two kinematic variables in the
dilepton channel. The variables are two reconstructed top quark masses from
different jets-to-quarks combinations and the invariant mass of two jets from
the decay in the lepton+jets channel, and a reconstructed top quark mass
and , a variable related to the transverse mass in events with two
missing particles, in the dilepton channel. The simultaneous fit of the
templates from signal and background events in the lepton+jets and dilepton
channels to the data yields a measured top quark mass of Comment: submitted to Phys. Rev.
Measurement of the Lifetime Difference Between B_s Mass Eigenstates
We present measurements of the lifetimes and polarization amplitudes for B_s
--> J/psi phi and B_d --> J/psi K*0 decays. Lifetimes of the heavy (H) and
light (L) mass eigenstates in the B_s system are separately measured for the
first time by determining the relative contributions of amplitudes with
definite CP as a function of the decay time. Using 203 +/- 15 B_s decays, we
obtain tau_L = (1.05 +{0.16}/-{0.13} +/- 0.02) ps and tau_H = (2.07
+{0.58}/-{0.46} +/- 0.03) ps. Expressed in terms of the difference DeltaGamma_s
and average Gamma_s, of the decay rates of the two eigenstates, the results are
DeltaGamma_s/Gamma_s = (65 +{25}/-{33} +/- 1)%, and DeltaGamma_s = (0.47
+{0.19}/-{0.24} +/- 0.01) inverse ps.Comment: 8 pages, 3 figures, 2 tables; as published in Physical Review Letters
on 16 March 2005; revisions are for length and typesetting only, no changes
in results or conclusion
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