Mediana de Aragón: organización y estudio de datos cerámicos con gestores relacionales de bancos de datos

Sin resume

Escolab: investigadores en el papel de divulgadores

EscoLab (http://www.escolab.cat) es una iniciativa del ICUB e IMEB del Ayuntamiento de Barcelona que brinda la oportunidad a jóvenes de interactuar con investigadores, conocer sus proyectos y participar en actividades a través de la visita sus centros de trabajo. Este estudio, realizado con la colaboración del ODC de la UAB, analiza la experiencia que ofrece Escolab para los investigadores participantes. En general, consideran que el programa funciona con éxito porque perciben que los jóvenes aprenden, se motivan, y mejoran la imagen que tienen de la ciencia. Los investigadoresdisfrutan devolviendo su conocimiento a la sociedad pero también reconocen sus limitaciones profesionales en materia de divulgación científica por lo que solicitan asesoría. Los resultados obtenidos permiten mejorar el impacto y calidad de las actividades de divulgación de EscoLab

Estrous cycle and ovariectomy-induced changes in visceral pain are microbiota-dependent

Visceral hypersensitivity (VH) is a hallmark of many functional gastrointestinal disorders including irritable bowel syndrome and is categorized by a dull, diffuse sensation of abdominal pain. Recently, the gut microbiota has been implicated in VH in male mice, but the effects in females have yet to be explored fully. To this end, we now show that somewhat surprisingly, female germ-free mice have similar visceral pain responses to colorectal distension (CRD) as their conventional controls. However, we show that although sensitivity to CRD is estrous cycle stage-dependent in conventional mice, it is not in germ-free mice. Further, ovariectomy (OVX) induced VH in conventional but not germ-free mice, and induced weight gain regardless of microbiota status. Finally, we show that estrogen-replacement ameliorated OVX-induced VH. Taken together, this study provides evidence for a major role of female sex hormones and the gut microbiota in sensation of visceral pain in females.Funding: This work was funded by Science Foundation Ireland through the Irish Government’s National Development Plan in the form of a center grant (APC Microbiome Institute Grant Number SFI/12/RC/2273_P2)

Fotógrafas españolas, luces y sombras en la Wikipedia

Este trabajo realiza una revisión de la presencia de fotógrafas españolas en Wikipedia. Para ello estudia la cobertura en la Wikipedia en castellano de las fotógrafas españolas, así como de aquellas nacidas en el extranjero que trabajaron en el país, nacidas hasta el año 1960. Para alcanzar los objetivos propuestos se ha llevado a cabo un estudio exploratorio, de carácter prospectivo, mediante la técnica del estudio de caso. This paper reviews the presence of Spanish women photographers in Wikipedia. For this purpose, it studies the coverage in the Spanish Wikipedia of Spanish women photographers, as well as those foreign-born women as well as those born abroad who worked in the country, born up to 1960. In order to achieve the proposed objectives, an exploratory, prospective study has been carried out using the case study technique

Obesity Takes Its Toll on Visceral Pain: High-Fat Diet Induces Toll-Like Receptor 4- Dependent Visceral Hypersensitivity

Exposure to high-fat diet induces both, peripheral and central alterations in TLR4 expression. Moreover, functional TLR4 is required for the development of high-fat diet-induced obesity. Recently, central alterations in TLR4 expression have been associated with the modulation of visceral pain. However, it remains unknown whether there is a functional interaction between the role of TLR4 in diet-induced obesity and in visceral pain. In the present study we investigated the impact of long-term exposure to high-fat diet on visceral pain perception and on the levels of TLR4 and Cd11b (a microglial cell marker) protein expression in the prefrontal cortex (PFC) and hippocampus. Peripheral alterations in TLR4 were assessed following the stimulation of spleenocytes with the TLR4-agonist LPS. Finally, we evaluated the effect of blocking TLR4 on visceral nociception, by administering TAK-242, a selective TLR4-antagonist. Our results demonstrated that exposure to high-fat diet induced visceral hypersensitivity. In parallel, enhanced TLR4 expression and microglia activation were found in brain areas related to visceral pain, the PFC and the hippocampus. Likewise, peripheral TLR4 activity was increased following long-term exposure to high-fat diet, resulting in an increased level of pro-inflammatory cytokines. Finally, TLR4 blockage counteracted the hyperalgesic phenotype present in mice fed on high-fat diet. Our data reveal a role for TLR4 in visceral pain modulation in a model of diet-induced obesity, and point to TLR4 as a potential therapeutic target for the development of drugs to treat visceral hypersensitivity present in pathologies associated to fat diet consumption

The recovery umbrella in the world of elite sport: Do not forget the coaching and performance staff

In the field of sports science, the recovery umbrella is a trending topic, and even more so in the world of elite sports. This is evidenced by the significant increase in scientific publications during the last 10 years as teams look to find a competitive edge. Recovery is recognized to be an integral component to assist athlete preparation in the restoration of physical and psychological function, and subsequently, performance in elite team sports athletes. However, the importance of recovery in team staff members (sports coaches and performance staff) in elite sports appears to be a forgotten element. Given the unrelenting intense nature of daily tasks and responsibilities of team staff members, the elite sports environment can predispose coaches to increased susceptibility to psycho-socio physiological fatigue burden, and negatively affect health, wellbeing, and performance. Therefore, the aim of this opinion was to (1) develop an educational recovery resource for team staff members, (2) identify organizational task-specific fatigue indicators and barriers to recovery and self-care in team staff members, and (3) present recovery implementation strategies to assist team staff members in meeting their organizational functions. It is essential that we do not forget the coaching and performance staff in the recovery process. © 2021 by the authors. Licensee MDPI, Basel, Switzerland

Non-nociceptive roles of opioids in the CNS: opioids' effects on neurogenesis, learning, memory and affect.

Mortality due to opioid use has grown to the point where, for the first time in history, opioid-related deaths exceed those caused by car accidents in many states in the United States. Changes in the prescribing of opioids for pain and the illicit use of fentanyl (and derivatives) have contributed to the current epidemic. Less known is the impact of opioids on hippocampal neurogenesis, the functional manipulation of which may improve the deleterious effects of opioid use. We provide new insights into how the dysregulation of neurogenesis by opioids can modify learning and affect, mood and emotions, processes that have been well accepted to motivate addictive behaviours

The Recovery Umbrella in the World of Elite Sport: Do Not Forget the Coaching and Performance Staff

In the field of sports science, the recovery umbrella is a trending topic, and even more so in the world of elite sports. This is evidenced by the significant increase in scientific publications during the last 10 years as teams look to find a competitive edge. Recovery is recognized to be an integral component to assist athlete preparation in the restoration of physical and psychological function, and subsequently, performance in elite team sports athletes. However, the importance of recovery in team staff members (sports coaches and performance staff) in elite sports appears to be a forgotten element. Given the unrelenting intense nature of daily tasks and responsibilities of team staff members, the elite sports environment can predispose coaches to increased susceptibility to psycho-socio physiological fatigue burden, and negatively affect health, wellbeing, and performance. Therefore, the aim of this opinion was to (1) develop an educational recovery resource for team staff members, (2) identify organizational task-specific fatigue indicators and barriers to recovery and self-care in team staff members, and (3) present recovery implementation strategies to assist team staff members in meeting their organizational functions. It is essential that we do not forget the coaching and performance staff in the recovery process

Reconstitución del edificio monumental de Contrebia Belaisca (Botorrita, Zaragoza)

El objetivo que nos hemos marcado en el presente trabajo ha sido llevar a término mediante diseño asistido por ordenador un proyecto que, desde hace varios años, se viene abordando de forma intermitente: la reconstrucción del edificio monumental de adobe de Contrebia Belaisca. Comenzamos por exponer, brevemente, los datos que actualmente tenemos acerca de las circunstancias hstóricas y económicas de la ciudad y de la construcción, efectuandouna mensuración detallada de esta última, incluyendo la descripción completa de su estructura interna y externa, y deduciendo la de los elementos arquitectónicos que no han llegado hasta nosotros. Finalmente, procedemos ala reconstrucción gráfica del edificio (mediante Autocad 9.0), presentando diversas vistas y perspectivas con objeto de ofrecer una idea lo más inteligible y aproximada posible de cómo era esta estructura. Adicionalmente, nuestro trabajo podrá servir como guía y base de discusión para acometer la rehabilitación material dela construcción