511 research outputs found
TEMPORAL AND SPATIAL DISTRIBUTION OF POACEAE POLLEN IN AREAS OF SOUTHERN UNITED KINGDOM, SPAIN AND PORTUGAL
Overall, longer Poaceae pollen seasons coincided with earlier pollen season start dates. Winter rainfall noticeably affects
the intensity of Poaceae pollen seasons in Mediterranean areas, but this was not as important in Worcester. Weekly data
from Worcester followed a similar pattern to that of Badajoz and Ăvora but at a distance of more than 1500 km and 4-5
weeks later
Comparison of fungal spores concentrations measured with wideband integrated bioaerosol sensor and Hirst methodology
The aim of this work was to provide both a comparison of traditional and novel methodologies for airborne spores detection (i.e. the Hirst Burkard trap and WIBS-4) and the first quantitative study of airborne fungal concentrations in Payerne (Western Switzerland) as well as their relation to meteorological parameters. From the traditional method -Hirst trap and microscope analysis-, sixty-three propagule types (spores, sporangia and hyphae) were identified and the average spore concentrations measured over the full period amounted to 4145 ± 263.0 spores/m3. Maximum values were reached on July 19th and on August 6th. Twenty-six spore types reached average levels above 10 spores/m3. Airborne fungal propagules in Payerne showed a clear seasonal pattern, increasing from low values in early spring to maxima in summer. Daily average concentrations above 5000 spores/m3 were almost constant in summer from mid-June onwards. Weather parameters showed a relevant role for determining the observed spore concentrations. Coniferous forest, dominant in the surroundings, may be a relevant source for airborne fungal propagules as their distribution and predominant wind directions are consistent with the origin. The comparison between the two methodologies used in this campaign showed remarkably consistent patterns throughout the campaign. A correlation coefficient of 0.9 (CI 0.76â0.96) was seen between the two over the time period for daily resolutions (Hirst trap and WIBS-4). This apparent co-linearity was seen to fall away once increased resolution was employed. However at higher resolutions upon removal of Cladosporium species from the total fungal concentrations (Hirst trap), an increased correlation coefficient was again noted between the two instruments (R = 0.81 with confidence intervals of 0.74 and 0.86)
High-precision measurements from LHC to FCC-ee
This document provides a writeup of all contributions to the workshop on
"High precision measurements of : From LHC to FCC-ee" held at CERN,
Oct. 12--13, 2015. The workshop explored in depth the latest developments on
the determination of the QCD coupling from 15 methods where high
precision measurements are (or will be) available. Those include low-energy
observables: (i) lattice QCD, (ii) pion decay factor, (iii) quarkonia and (iv)
decays, (v) soft parton-to-hadron fragmentation functions, as well as
high-energy observables: (vi) global fits of parton distribution functions,
(vii) hard parton-to-hadron fragmentation functions, (viii) jets in p
DIS and -p photoproduction, (ix) photon structure function in
-, (x) event shapes and (xi) jet cross sections in
collisions, (xii) W boson and (xiii) Z boson decays, and (xiv) jets and (xv)
top-quark cross sections in proton-(anti)proton collisions. The current status
of the theoretical and experimental uncertainties associated to each extraction
method, the improvements expected from LHC data in the coming years, and future
perspectives achievable in collisions at the Future Circular Collider
(FCC-ee) with (1--100 ab) integrated luminosities yielding
10 Z bosons and jets, and 10 W bosons and leptons, are
thoroughly reviewed. The current uncertainty of the (preliminary) 2015 strong
coupling world-average value, = 0.1177 0.0013, is about
1\%. Some participants believed this may be reduced by a factor of three in the
near future by including novel high-precision observables, although this
opinion was not universally shared. At the FCC-ee facility, a factor of ten
reduction in the uncertainty should be possible, mostly thanks to
the huge Z and W data samples available.Comment: 135 pages, 56 figures. CERN-PH-TH-2015-299, CoEPP-MN-15-13. This
document is dedicated to the memory of Guido Altarell
Single cell profiling of COVID-19 patients: an international data resource from multiple tissues
In late 2019 and through 2020, the COVID-19 pandemic swept the world, presenting both scientific and medical challenges associated with understanding and treating a previously unknown disease. To help address the need for great understanding of COVID-19, the scientific community mobilized and banded together rapidly to characterize SARS-CoV-2 infection, pathogenesis and its distinct disease trajectories. The urgency of COVID-19 provided a pressing use-case for leveraging relatively new tools, technologies, and nascent collaborative networks. Single-cell biology is one such example that has emerged over the last decade as a powerful approach that provides unprecedented resolution to the cellular and molecular underpinnings of biological processes. Early foundational work within the single-cell community, including the Human Cell Atlas, utilized published and unpublished data to characterize the putative target cells of SARS-CoV-2 sampled from diverse organs based on expression of the viral receptor ACE2 and associated entry factors TMPRSS2 and CTSL (Muus et al., 2020; Sungnak et al., 2020; Ziegler et al., 2020). This initial characterization of reference data provided an important foundation for framing infection and pathology in the airway as well as other organs. However, initial community analysis was limited to samples derived from uninfected donors and other previously-sampled disease indications. This report provides an overview of a single-cell data resource derived from samples from COVID-19 patients along with initial observations and guidance on data reuse and exploration
Soft, collinear and non-relativistic modes in radiative decays of very heavy quarkonium
We analyze the end-point region of the photon spectrum in semi-inclusive
radiative decays of very heavy quarkonium (m alpha_s^2 >> Lambda_QCD). We
discuss the interplay of the scales arising in the Soft-Collinear Effective
Theory, m, m(1-z)^{1/2} and m(1-z) for z close to 1, with the scales of heavy
quarkonium systems in the weak coupling regime, m, m alpha_s and m alpha_s^2.
For 1-z \sim alpha_s^2 only collinear and (ultra)soft modes are seen to be
relevant, but the recently discovered soft-collinear modes show up for 1-z <<
alpha_s^2. The S- and P-wave octet shape functions are calculated. When they
are included in the analysis of the photon spectrum of the Upsilon (1S) system,
the agreement with data in the end-point region becomes excellent. The NRQCD
matrix elements and
are also obtained.Comment: Revtex, 11 pages, 6 figures. Minor improvements and references added.
Journal versio
Physics at BES-III
This physics book provides detailed discussions on important topics in
-charm physics that will be explored during the next few years at \bes3 .
Both theoretical and experimental issues are covered, including extensive
reviews of recent theoretical developments and experimental techniques. Among
the subjects covered are: innovations in Partial Wave Analysis (PWA),
theoretical and experimental techniques for Dalitz-plot analyses, analysis
tools to extract absolute branching fractions and measurements of decay
constants, form factors, and CP-violation and \DzDzb-oscillation parameters.
Programs of QCD studies and near-threshold tau-lepton physics measurements are
also discussed.Comment: Edited by Kuang-Ta Chao and Yi-Fang Wan
Heavy quarkonium: progress, puzzles, and opportunities
A golden age for heavy quarkonium physics dawned a decade ago, initiated by
the confluence of exciting advances in quantum chromodynamics (QCD) and an
explosion of related experimental activity. The early years of this period were
chronicled in the Quarkonium Working Group (QWG) CERN Yellow Report (YR) in
2004, which presented a comprehensive review of the status of the field at that
time and provided specific recommendations for further progress. However, the
broad spectrum of subsequent breakthroughs, surprises, and continuing puzzles
could only be partially anticipated. Since the release of the YR, the BESII
program concluded only to give birth to BESIII; the -factories and CLEO-c
flourished; quarkonium production and polarization measurements at HERA and the
Tevatron matured; and heavy-ion collisions at RHIC have opened a window on the
deconfinement regime. All these experiments leave legacies of quality,
precision, and unsolved mysteries for quarkonium physics, and therefore beg for
continuing investigations. The plethora of newly-found quarkonium-like states
unleashed a flood of theoretical investigations into new forms of matter such
as quark-gluon hybrids, mesonic molecules, and tetraquarks. Measurements of the
spectroscopy, decays, production, and in-medium behavior of c\bar{c}, b\bar{b},
and b\bar{c} bound states have been shown to validate some theoretical
approaches to QCD and highlight lack of quantitative success for others. The
intriguing details of quarkonium suppression in heavy-ion collisions that have
emerged from RHIC have elevated the importance of separating hot- and
cold-nuclear-matter effects in quark-gluon plasma studies. This review
systematically addresses all these matters and concludes by prioritizing
directions for ongoing and future efforts.Comment: 182 pages, 112 figures. Editors: N. Brambilla, S. Eidelman, B. K.
Heltsley, R. Vogt. Section Coordinators: G. T. Bodwin, E. Eichten, A. D.
Frawley, A. B. Meyer, R. E. Mitchell, V. Papadimitriou, P. Petreczky, A. A.
Petrov, P. Robbe, A. Vair
Physical activity of subjects aged 50â64 years involved in the European Prospective Investigation into Cancer and Nutrition (EPIC)
Objective: To describe physical activity of participants in the European Prospective Investigation into Cancer and Nutrition (EPIC). Design: A cross-sectional analysis of baseline data of a European prospective cohort study. Subjects: This analysis was restricted to participants in the age group 50-64 years, which was represented in all EPIC centres. It involved 236 386 participants from 25 centres in nine countries. In each EPIC centre, physical activity was assessed by standardised and validated questions. Frequency distribution of type of professional activity and participation in non-professional activities, and age-adjusted means, medians and percentiles of time dedicated to non-professional activities are presented for men and women from each centre. Results: Professional activity was most frequently classified as sedentary or standing in all centres. There was a wide variation regarding participation in different types of non-professional activities and time dedicated to these activities across EPIC centres. Over 80% of all EPIC participants engaged in walking, while less than 50% of the subjects participated in sport. Total time dedicated to recreational activities was highest among the Dutch participants and lowest among men from Malmo (Sweden) and women from Naples (Italy). In all centres, total time dedicated to recreational activity in the summer was higher than in the winter. Women from southern Europe spent the most time on housekeeping. Conclusions: There is a considerable variation of physical activity across EPIC centres. This variation was especially evident for recreational activities in both men and women
Blood pressure and risk of renal cell carcinoma in the European prospective investigation into cancer and nutrition.
Elevated blood pressure has been implicated as a risk factor for renal cell carcinoma (RCC), but prospective studies were confined to men and did not consider the effect of antihypertensive medication. The authors examined the relation among blood pressure, antihypertensive medication, and RCC in the European Prospective Investigation into Cancer and Nutrition (EPIC). Blood pressure was measured in 296,638 women and men, recruited in eight European countries during 1992-1998, 254,935 of whom provided information on antihypertensive medication. During a mean follow-up of 6.2 years, 250 cases of RCC were identified. Blood pressure was independently associated with risk of RCC. The relative risks for the highest versus the lowest category of systolic (>/=160 mmHg vs. /=100 mmHg vs. <80 mmHg) blood pressures were 2.48 (95% confidence interval: 1.53, 4.02) and 2.34 (95% confidence interval: 1.54, 3.55). Risk estimates did not significantly differ according to sex or use of antihypertensive medication. Individuals taking antihypertensive drugs were not at a significantly increased risk unless blood pressure was poorly controlled. These results support the hypothesis that hypertension, rather than its medications, increases the risk of RCC in both sexes, while effective blood pressure control may lower the risk. Udgivelsesdato: 2008-Feb-1
A roadmap for the Human Developmental Cell Atlas
The Human Developmental Cell Atlas (HDCA) initiative, which is part of the Human Cell Atlas, aims to create a comprehensive reference map of cells during development. This will be critical to understanding normal organogenesis, the effect of mutations, environmental factors and infectious agents on human development, congenital and childhood disorders, and the cellular basis of ageing, cancer and regenerative medicine. Here we outline the HDCA initiative and the challenges of mapping and modelling human development using state-of-the-art technologies to create a reference atlas across gestation. Similar to the Human Genome Project, the HDCA will integrate the output from a growing community of scientists who are mapping human development into a unified atlas. We describe the early milestones that have been achieved and the use of human stem-cell-derived cultures, organoids and animal models to inform the HDCA, especially for prenatal tissues that are hard to acquire. Finally, we provide a roadmap towards a complete atlas of human development
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