The Solar Neighborhood. XIX. Discovery and Characterization of 33 New Nearby White Dwarf Systems

We present spectra for 33 previously unclassified white dwarf systems brighter than V = 17 primarily in the southern hemisphere. Of these new systems, 26 are DA, 4 are DC, 2 are DZ, and 1 is DQ. We suspect three of these systems are unresolved double degenerates. We obtained VRI photometry for these 33 objects as well as for 23 known white dwarf systems without trigonometric parallaxes, also primarily in the southern hemisphere. For the 56 objects, we converted the photometry values to fluxes and fit them to a spectral energy distribution using the spectroscopy to determine which model to use (i.e. pure hydrogen, pure helium, or metal-rich helium), resulting in estimates of effective temperature and distance. Eight of the new and 12 known systems are estimated to be within the NStars and Catalogue of Nearby Stars (CNS) horizons of 25 pc, constituting a potential 18% increase in the nearby white dwarf sample. Trigonometric parallax determinations are underway via CTIOPI for these 20 systems. One of the DCs is cool so that it displays absorption in the near infrared. Using the distance determined via trigonometric parallax, we are able to constrain the model-dependent physical parameters and find that this object is most likely a mixed H/He atmosphere white dwarf similar to other cool white dwarfs identified in recent years with significant absorption in the infrared due to collision-induced absorptions by molecular hydrogen.Comment: 33 pages, 10 figures, accepted for publication in the Astronomical Journa

Beyond cAMP: The Regulation of Akt and GSK3 by Dopamine Receptors

Brain dopamine receptors have been preferred targets for numerous pharmacological compounds developed for the treatment of various neuropsychiatric disorders. Recent discovery that D2 dopamine receptors, in addition to cAMP pathways, can engage also in Akt/GSK3 signaling cascade provided a new framework to understand intracellular signaling mechanisms involved in dopamine-related behaviors and pathologies. Here we review a recent progress in understanding the role of Akt, GSK3, and related signaling molecules in dopamine receptor signaling and functions. Particularly, we focus on the molecular mechanisms involved, interacting partners, role of these signaling events in the action of antipsychotics, psychostimulants, and antidepressants as well as involvement in pathophysiology of schizophrenia, bipolar disorder, and Parkinson’s disease. Further understanding of the role of Akt/GSK3 signaling in dopamine receptor functions could provide novel targets for pharmacological interventions in dopamine-related disorders

The Solar Neighborhood XVII: Parallax Results from the CTIOPI 0.9m Program -- Twenty New Members of the RECONS 10 Parsec Sample

Astrometric measurements for 25 red dwarf systems are presented, including the first definitive trigonometric parallaxes for 20 systems within 10 pc of the Sun, the horizon of the RECONS sample. The three nearest systems that had no previous trigonometric parallaxes (other than perhaps rough preliminary efforts) are SO 0253+1652 (3.84 +/- 0.04 pc, the 23rd nearest system), SCR 1845-6357 AB (3.85 +/- 0.02 pc, 24th), and LHS 1723 (5.32 +/- 0.04 pc, 56th). In total, seven of the systems reported here rank among the nearest 100 stellar systems. Supporting photometric and spectroscopic observations have been made to provide full characterization of the systems, including complete VRIJHK photometry and spectral types. A study of the variability of 27 targets reveals six obvious variable stars, including GJ 1207, for which we observed a flare event in the V band that caused it to brighten by 1.7 mag. Improved parallaxes for GJ 54 AB and GJ 1061, both important members of the 10 pc sample, are also reported. Definitive parallaxes for GJ 1001 A, GJ 633, and GJ 2130 ABC, all of which have been reported to be within 10 pc, indicate that they are beyond 10 pc. From the analysis of systems with (previously) high trigonometric parallax errors, we conclude that parallaxes with errors in excess of 10 mas are insufficiently reliable for inclusion in the RECONS sample. The cumulative total of new additions to the 10 pc sample since 2000 is now 34 systems -- 28 by the RECONS team and six by other groups. This total represents a net increase of 16% in the number of stellar systems reliably known to be nearer than 10 pc.Comment: 33 pages, including 3 figures and 3 table

A global map to aid the identification and screening of critical habitat for marine industries

Marine industries face a number of risks that necessitate careful analysis prior to making decisions on the siting of operations and facilities. An important emerging regulatory framework on environmental sustainability for business operations is the International Finance Corporation’s Performance Standard 6 (IFC PS6). Within PS6, identification of biodiversity significance is articulated through the concept of “Critical Habitat”, a definition developed by the IFC and detailed through criteria aligned with those that support internationally accepted biodiversity designations. No publicly available tools have been developed in either the marine or terrestrial realm to assess the likelihood of sites or operations being located within PS6-defined Critical Habitat. This paper presents a starting point towards filling this gap in the form of a preliminary global map that classifies more than 13 million km2 of marine and coastal areas of importance for biodiversity (protected areas, Key Biodiversity Areas [KBA], sea turtle nesting sites, cold- and warm-water corals, seamounts, seagrass beds, mangroves, saltmarshes, hydrothermal vents and cold seeps) based on their overlap with Critical Habitat criteria, as defined by IFC. In total, 5798×103 km2 (1.6%) of the analysis area (global ocean plus coastal land strip) were classed as Likely Critical Habitat, and 7526×103 km2 (2.1%) as Potential Critical Habitat; the remainder (96.3%) were Unclassified. The latter was primarily due to the paucity of biodiversity data in marine areas beyond national jurisdiction and/or in deep waters, and the comparatively fewer protected areas and KBAs in these regions. Globally, protected areas constituted 65.9% of the combined Likely and Potential Critical Habitat extent, and KBAs 29.3%, not accounting for the overlap between these two features. Relative Critical Habitat extent in Exclusive Economic Zones varied dramatically between countries. This work is likely to be of particular use for industries operating in the marine and coastal realms as an early screening aid prior to in situ Critical Habitat assessment; to financial institutions making investment decisions; and to those wishing to implement good practice policies relevant to biodiversity management. Supplementary material (available online) includes other global datasets considered, documentation and justification of biodiversity feature classification, detail of IFC PS6 criteria/scenarios, and coverage calculations

The Solar Neighborhood X: New Nearby Stars in the Southern Sky and Accurate Photometric Distance Estimates for Red Dwarfs

Photometric VRI and spectroscopic (6000-9500 A) observations of high proper motion stars discovered during the first phase of the SuperCOSMOS RECONS (SCR) search are used to estimate accurate distances to eight new nearby red dwarfs, including probable 10 pc sample members SCR 1845-6357 (M8.5V at 4.6 pc), the binary SCR 0630-7643AB (M6.0VJ at 7.0 pc), and SCR 1138-7721 (M5.0V at 9.4 pc). Distance estimates are determined using a suite of new photometric color-Mk relations defined using a robust set of nearby stars with accurate VRIJHK photometry and trigonometric parallaxes. These relations are utilized, with optical and infrared photometry, to estimate distances on a uniform system (generally good to 15%) for two additional samples of red nearby star candidates: several recently discovered members of the solar neighborhood, and known faint stars with proper motions in excess of 1.0"/yr south of DEC = -57.5. Of those without accurate trigonometric parallax measurements, there are five stars in the first sample and three in the second that are likely to be within 10 pc. The two nearest are SO 0253+1652 (M7.0V at 3.7 pc) and DEN 1048-3956 (M8.5V at 4.5 pc). When combined with SCR 1845-6357, these three stars together represent the largest increase in the 5 pc sample in several decades. Red spectra are presented for the red dwarfs and types are given on the RECONS standard spectral system. Red spectra are also given for two new nearby white dwarfs for which we estimate distances from the photometry of less than 20 pc -- WD 0141-675 (LHS 145, 9.3 pc) and SCR 2012-5956 (17.4 pc). WD 0141-675 brings the total number of systems nearer than 10 pc discussed in this paper to 12.Comment: accepted to The Astronomical Journal (scheduled for November 2004 issue

Dopamine Inhibits Mitochondrial Motility in Hippocampal Neurons

The trafficking of mitochondria within neurons is a highly regulated process. In an earlier study, we found that serotonin (5-HT), acting through the 5-HT1A receptor subtype, promotes axonal transport of mitochondria in cultured hippocampal neurons by increasing Akt activity, and consequently decreasing glycogen synthase kinase (GSK3beta) activity. This finding suggests a critical role for neuromodulators in the regulation of mitochondrial trafficking in neurons. In the present study, we investigate the effects of a second important neuromodulator, dopamine, on mitochondrial transport in hippocampal neurons.Here, we show that dopamine, like 5-HT, regulates mitochondrial motility in cultured hippocampal neurons through the Akt-GSK3beta signaling cascade. But, in contrast to the stimulatory effect of 5-HT, administration of exogenous dopamine or bromocriptine, a dopamine 2 receptor (D2R) agonist, caused an inhibition of mitochondrial movement. Moreover, pretreatment with bromocriptine blocked the stimulatory effect of 5-HT on mitochondrial movement. Conversely, in cells pretreated with 5-HT, no further increases in movement were observed after administration of haloperidol, a D2R antagonist. In contrast to the effect of the D2R agonist, addition of SKF38393, a dopamine 1 receptor (D1R) agonist, promoted mitochondrial transport, indicating that the inhibitory effect of dopamine was actually the net summation of opposing influences of the two receptor subtypes. The most pronounced effect of dopamine signals was on mitochondria that were already moving directionally. Western blot analysis revealed that treatment with either a D2R agonist or a D1R antagonist decreased Akt activity, and conversely, treatment with either a D2R antagonist or a D1R agonist increased Akt activity.Our observations strongly suggest a role for both dopamine and 5-HT in regulating mitochondrial movement, and indicate that the integrated effects of these two neuromodulators may be important in determining the distribution of energy sources in neurons

Angular momentum sharing in dissipative collisions

Light charged particles emitted by the projectile-like fragment were measured in the direct and reverse collision of $^{93}$Nb and $^{116}$Sn at 25 AMeV. The experimental multiplicities of Hydrogen and Helium particles as a function of the primary mass of the emitting fragment show evidence for a correlation with net mass transfer. The ratio of Hydrogen and Helium multiplicities points to a dependence of the angular momentum sharing on the net mass transfer.Comment: 8 pages, 2 figure

The JCMT Gould Belt Survey: Evidence for radiative heating in Serpens MWC 297 and its influence on local star formation

We present SCUBA-2 450micron and 850micron observations of the Serpens MWC 297 region, part of the JCMT Gould Belt Survey of nearby star-forming regions. Simulations suggest that radiative feedback influences the star-formation process and we investigate observational evidence for this by constructing temperature maps. Maps are derived from the ratio of SCUBA-2 fluxes and a two component model of the JCMT beam for a fixed dust opacity spectral index of beta = 1.8. Within 40 of the B1.5Ve Herbig star MWC 297, the submillimetre fluxes are contaminated by free-free emission with a spectral index of 1.03+-0.02, consistent with an ultra-compact HII region and polar winds/jets. Contamination accounts for 73+-5 per cent and 82+-4 per cent of peak flux at 450micron and 850micron respectively. The residual thermal disk of the star is almost undetectable at these wavelengths. Young Stellar Objects are confirmed where SCUBA-2 850micron clumps identified by the fellwalker algorithm coincide with Spitzer Gould Belt Survey detections. We identify 23 objects and use Tbol to classify nine YSOs with masses 0.09 to 5.1 Msun. We find two Class 0, one Class 0/I, three Class I and three Class II sources. The mean temperature is 15+-2K for the nine YSOs and 32+-4K for the 14 starless clumps. We observe a starless clump with an abnormally high mean temperature of 46+-2K and conclude that it is radiatively heated by the star MWC 297. Jeans stability provides evidence that radiative heating by the star MWC 297 may be suppressing clump collapse.Comment: 24 pages, 13 figures, 7 table

Transiting extrasolar planetary candidates in the Galactic bulge

More than 200 extrasolar planets have been discovered around relatively nearby stars, primarily through the Doppler line shifts owing to the reflex motions of their host stars, and more recently through transits of some planets across the face of the host stars. The detection of planets with the shortest known periods, 1.2 to 2.5 days, has mainly resulted from transit surveys which have generally targeted stars more massive than 0.75 M_sun. Here we report the results from a planetary transit search performed in a rich stellar field towards the Galactic bulge. We discovered 16 candidates with orbital periods between 0.4 and 4.2 days, five of which orbit stars of 0.44 to 0.75 M_sun. In two cases, radial-velocity measurements support the planetary nature of the companions. Five candidates have orbital periods below 1.0 day, constituting a new class of ultra-short-period planets (USPPs), which occur only around stars of less than 0.88 M_sun. This indicates that those orbiting very close to more luminous stars might be evaporatively destroyed, or that jovian planets around lower-mass stars might migrate to smaller radii.Comment: To appear in October 5, 2006 issue of Natur

The EROS2 search for microlensing events towards the spiral arms: the complete seven season results

The EROS-2 project has been designed to search for microlensing events towards any dense stellar field. The densest parts of the Galactic spiral arms have been monitored to maximize the microlensing signal expected from the stars of the Galactic disk and bulge. 12.9 million stars have been monitored during 7 seasons towards 4 directions in the Galactic plane, away from the Galactic center. A total of 27 microlensing event candidates have been found. Estimates of the optical depths from the 22 best events are provided. A first order interpretation shows that simple Galactic models with a standard disk and an elongated bulge are in agreement with our observations. We find that the average microlensing optical depth towards the complete EROS-cataloged stars of the spiral arms is $\bar{\tau} =0.51\pm .13\times 10^{-6}$, a number that is stable when the selection criteria are moderately varied. As the EROS catalog is almost complete up to $I_C=18.5$, the optical depth estimated for the sub-sample of bright target stars with $I_C<18.5$ ($\bar{\tau}=0.39\pm >.11\times 10^{-6}$) is easier to interpret. The set of microlensing events that we have observed is consistent with a simple Galactic model. A more precise interpretation would require either a better knowledge of the distance distribution of the target stars, or a simulation based on a Galactic model. For this purpose, we define and discuss the concept of optical depth for a given catalog or for a limiting magnitude.Comment: 22 pages submitted to Astronomy & Astrophysic