Nutritional and Health Profile of Goat Products: Focus on Health Benefits of Goat Milk

Goat (Capra hircus) is one of the main sources of milk and meat products for human consumption. Goat milk differs from cow and human milk in both composition and nutritional properties. Goat milk and other goat-derived products contain several bioactive compounds that might be useful in patients suffering from a variety of chronic diseases. Several peptides, fats, and oligosaccharides present in goat’s milk can be potentially useful in cardiovascular disease, metabolic disorders, neurological degeneration, or in promoting intestinal health. They have also shown chemopreventive properties in cancer. In addition, the oligosaccharides present in goat’s milk have immunomodulatory properties, prevent adhesion of pathogenic bacteria, and have prebiotic, probifidogenic effects. Due to its potential health benefits, goat milk is particularly recommended for infants, older adults, and convalescing people. This chapter gives an overview of the biological activities of goat products and the effects of peptides, fats, and oligosaccharides present in goat milk on pathogenic bacteria, as well as their ability to regulate immunological, gastrointestinal, hormonal, and neurological responses in humans

Occupational exposure of firefighters to polycyclic aromatic hydrocarbons in non-fire work environments

This work aims to characterize personal exposure of firefighters to polycyclic aromatic hydrocarbons (PAHs) in non-fire work environments (fire stations), and assesses the respective risks. Eighteen PAHs (16 considered by USEPA as priority pollutants, dibenzo[a,l] pyrene and benzo[j] fluoranthene) were monitored in breathing zones of workers at five Portuguese fire stations during a normal shift. The obtained levels of PAHs fulfilled all existent occupational exposure limits as well as air quality guidelines with total concentrations (Sigma PAHs) in range of 46.8-155 ng m(-3). Light compounds (2-3 rings) were the most predominant congeners (74-96% of Sigma PAHs) whereas PAHs with 5-6 rings accounted 3-9% of Sigma PAHs. Fuel and biomass combustions, vehicular traffic emissions, and use of lubricant oils were identified as the main sources of PAHs exposure at the studied fire corporations. Incremental lifetime cancer risks were below the recommend USEPA guideline of 10(-6) and thus negligible for all the studied subjects, but WHO health-based guideline level of 10(-5) was exceeded (9-44 times) at all fire corporations. These results thus show that even during non-fire situations firefighters are exposed to PAHs at levels that may promote some adverse health outcomes; therefore the respective occupational exposures to these compounds should be carefully controlled. (C) 2017This work was supported by European Union (FEDER funds through COMPETE) and National Funds (Fundação para a Ciência e Tecnologia) through projects UID/QUI/50006/2013, POCI/01/0145/FEDER/007265 and UID/EQU/00511/2013-LEPABE, by the FCT/MECwith national funds and co-funded by FEDER in the scope of the P2020 Partnership Agreement. Additional financial support was provided by Fundação para Ciência e Tecnologia through fellowships SFRH/BD/80113/2011 and SFRH/BPD/105100/2014. The authors are thankful to all firefighters involved in the study and to collaborators from Escola Superior de Saúde from Instituto Politécnico de Bragança.info:eu-repo/semantics/publishedVersio

Idosos institucionalizados no concelho de Viseu: Hábitos alimentares

O envelhecimento da população, bem como a alteração da dinâmica da família, têm contribuído diretamente para o aumento do número de idosos institucionalizados. A incidência da desnutrição alcança níveis elevados nestes idosos, sendo essencial o seu diagnóstico precoce para a melhoria da sua qualidade de vida. Constitui objetivo primordial do estudo a avaliação do estado nutricional de idosos institucionalizados no concelho de Viseu, Portugal. A amostra (n=120) é constituída por idosos de ambos os sexos, institucionalizados, com idade igual ou superior a 65 anos, com capacidade para se colocar de pé, sem demência e que não sejam portadores de patologia passível de afetar a digestão, absorção ou utilização dos nutrientes. A avaliação do estado nutricional é determinada tendo em conta parâmetros antropométricos e dietéticos, através da avaliação da ingestão alimentar (registo de 3 dias) e Mini Nutricional Assessment (MNA). Os questionários aplicados estão validados para a população portuguesa idosa e foram aplicados após consentimento informado. Considerou-se um nível de confiança de 95%. A amostra estudada é maioritariamente feminina (70,0%), com uma idade média de 82,4±6,4 anos. A determinação do IMC mostrou que 12,5% dos idosos avaliados têm baixo peso (IMC 17,7±1,3); 46,7% são eutróficos (IMC 19,9±0,5); 11,7% apresentam excesso de peso (IMC 22,1±0,7), sendo 29,1% classificados como obesos (IMC 28,8±4,2). O MNA mostra que 65% dos idosos apresenta estado nutricional normal, estando sob risco de desnutrição 33,3%, verificando-se, este risco de desnutrição ser superior nos idosos ≥ 75 anos e na população feminina (3:1). A ingestão energética média por dia é significativamente inferior à recomendada (p≤0,05), sendo a ingesta de proteína e hidratos de carbono superior aos valores recomendados para a população (p≤0,05). O consumo lipídico é maioritariamente normolipídico (54,1%), devendo-se a um consumo reduzido de ácidos gordos monosaturados vs. polinsaturados.info:eu-repo/semantics/publishedVersio

Radon exhalation from uranium tailings. Comparison of experimental and theoretical data

Two different experimental methods and a theoretical approach are used to calculate 222Rn fluxes in the soil-atmosphere interface. As a common experimental procedure, an open-faced 30 liters cylindrical container was inverted and placed onto the tailing surface with the open face down. After a 24 h period, to balance any possible disturbance, the interior air was analysed. One of the experimental methods is based on integrated 222Rn measurements of the accumulated air-gas mixture, using solid nuclear track detectors placed inside the container. The other method is based on spot air samples using scintillation cells, being the 222Rn concentration measured in equilibrium. The radon flux theoretical values are estimated from the 226Ra content of the tailings material, determined by gamma spectrometry, and using the diffusion equation. The series of results obtained by the referred methods were compared

Biomonitoring of firefighters occupational exposure to polycyclic aromatic hydrocarbons during the 2014 hot season

Human biomonitoring is an important tool in environmental medicine that is used to assess the level of internal exposure to environmental pollutants. Firefighters are one of the most exposed and least studied occupations. During fire suppression, firefighters are heavily exposed to a wide range of chemicals. Polycyclic aromatic hydrocarbons (PAH) are ubiquitous environmental pollutants that are considered as the largest known group of carcinogens due to their cytotoxic and mutagenic properties. Smoke and ashes released during a fire are important sources of PAH. Firefighters can be also exposed to PAH through smoking, via polluted ambient air, water, soil, and through consumption of food. Metabolites of PAH (OH-PAHs), such as 1-hydroxynaphthalene (1OHNapt), 1-hydroxyacenaphthene(1OHAce), 1-hydroxypyrene (1OHPy) and 3-hydroxybenzo[a]pyrene (3OHB[a]P) have been used as biological markers for measurements of human internal exposure to PAH. The present work aims to quantify the urinary metabolites of PAH, namely 1OHNapt, 1OHAce, 1OHPy and 3OHB[a]P in study population of firefighters. Firemen exposed to fires that occurred during 2014 season were asked to fill a post-fire questionnaire and to collect urinary samples. A control study population group was selected to collect samples of urines during the pre-fires season (winter). Among all participating firemen only healthy no-smoking subjects were considered. OH-PAHs were analysed by high-performance liquid chromatography with fluorescence detection. Overall, 1OHNapt and 1OHAce were the most abundant OH-PAHs in firemen urine samples, accounting for approximately 90% of the total OH-PAHs. The urinary OH-PAHs in exposed firefighters were higher than those of control group. Data collected with the individual questionnaire were further used to analyse the concentrations of OH-PAH between (and within) control and exposed groups of firemen. Additionally, 1OHPy concentrations in the exposed firefighters will be compared with the available proposed guidelines

End-Stage Renal Disease in Familial Amyloidosis ATTR Val30Met: A

Transplant Proc. 2003 May;35(3):1116-20. End-stage renal disease in familial amyloidosis ATTR Val30Met: a definitive indication to combined liver-kidney transplantation. Lobato L, Ventura A, Beirão I, Miranda HP, Seca R, Henriques AC, Teixeira M, Sarmento AM, Pereira MC. Department of Nephrology, and Liver Transplantation Program, Hospital Geral de Santo António, Largo Professor Abel Salazar, 4050, Porto, Portugal. [email protected] PMID: 12947881 [PubMed - indexed for MEDLINE

Effects of a plyometric training program in sub-elite futsal players during pre-season period

Plyometric training (PT) programs can improve several motor skills during the pre-season. Even so, its impact during the pre-season specifically in futsal remains unclear. Objective: The present observational study examines the impact of a six-week PT program that included varied strength exercises in adult male futsal players. Method: Fourteen futsal players from a Portuguese men’s sub-elite team that competed in a national championship (mean ± Standard deviation (SD) age: 25.78±7.05 years) were included in this cross-sectional study that analyzed the consequences of a PT program during the pre-season, followed by four weeks of detraining. Players were monitored 3 times: at the beginning, after six weeks of PT and four weeks after the end of PT. Results: The current research presented significant mean changes with the application of the training program in the three assessment moments for agility (small to moderate effect), countermovement jump (CMJ) height (trivial to small effect), and sprint performance (trivial to moderate large effect). When assessing the mean differences between pre- and post-training, the differences are more evident in their magnitude (Δ = -12.73 to 3.69%, d = 0.38 to 2.08). Furthermore, the PT program showed the greatest influence on 20 m sprint with a large effect (Δ = -12.73%, d = 2.08), followed by a small and moderate effect for agility (Δ = -6.46%, d = 0.85) and for the 10 m sprint (Δ = -3.53%, d = 0.38). Conclusions: These results confirmed the impact of a six-week plyometric training during the pre-season in sub-elite futsal players. This new evidence can be particularly useful in pre-season planning in futsal. (c) the author(s).This work is suppoted by national funding through the Portuguese Foundation for Science and Technology I.P., under project UIDB/04045/2020info:eu-repo/semantics/publishedVersio

Urinary levels of monohydroxyl PAH metabolites in portuguese firefighters: background levels and impact of tobacco smoke

Firefighting occupational exposure is classified as possible carcinogen to humans by the International Agency for Research on Cancer and the US National Institute for Occupational Safety and Health [1,2]. Tobacco smoke is a very important factor in the assessment of occupational exposure of workers, since the prolonged exposure to tobacco smoke is by itself the major cause of lung cancer [3]. The consumption of tobacco is responsible for the exposure to many smoke components including more than sixty known carcinogens, including some polycyclic aromatic hydrocarbons (PAHs) [4]. PAHs are ubiquitous compounds formed during pyrolysis or incomplete combustion of organic matter, being well-known for their toxic, mutagenic, and carcinogenic properties to humans [5,6]. So far, the impact of tobacco smoke on firefighters’ total exposure to PAHs is very limited.info:eu-repo/semantics/publishedVersio

Development of a tomato spotted wilt virus (TSWV) risk evaluation methology for a processing tomato region

A risk map for the Tomato spotted wilt virus (TSWV) was elaborated for the main Portuguese processing tomato producing region, the “Ribatejo e Península de Setúbal” region, where periodically this virus causes severe losses. Forty nine tomato fields were monitored. Risk factors for TSWV infection were identified and quantified according to their relative importance in TSWV incidence. The risk factors considered for each field were: (1) presence of TSWV in tomato plants; (2) presence of TSWV in weeds which are hosts of TSWV vectors; (3) presence of TSWV vector thrips; (4) presence of TSWV host crops previously (in the two years before), namely, tomato, potato and sweet pepper; and (5) presence of greenhouses, urban areas or TSWV host crops next to the field (up to about 100m from its borders). A risk estimator was calculated for each field. Among the thrips (Thysanoptera) identified, belonging to 11 genera, four vector thrips species were detected: Frankliniella occidentalis (Pergande) and Thrips tabaci Lindman, the two most abundant ones, and F. intonsa (Trybom) and F. schultzei (Trybom). Blue sticky traps placed up to about 75 cm above the crop canopy caught F. occidentalis and T. tabaci more efficiently than the beating technique. The weeds Datura stramonium L., Arctotheca calendula (L.), and Conyza bonariensis (L.) were identified as TSWV winter repositories. This study proposes a methodology to be used by field technicians for the annual evaluation of TSWV risk at a regional level, for an improved planning of processing tomato crop in the following season

Firefighters exposure to fire emissions: Impact on levels of biomarkers of exposure to polycyclic aromatic hydrocarbons and genotoxic/oxidative-effects

Firefighters represent one of the riskiest occupations, yet due to the logistic reasons, the respective exposure assessment is one of the most challenging. Thus, this work assessed the impact of firefighting activities on levels of urinary monohydroxyl-polycyclic aromatic hydrocarbons (OHPAHs; 1-hydroxynaphthalene, 1-hydroxyacenaphthene, 2-hydroxyfluorene, 1-hydroxyphenanthrene, 1-hydroxypyrene, 3-hydroxybenzo(a)pyrene) and genotoxic/oxidative-effect biomarkers (basal DNA and oxidative DNA damage) of firefighters from eight firehouses. Cardiac frequency, blood pressure and arterial oxygen saturation were also monitored. OHPAHs were determined by liquid-chromatography with fluorescence detection, while genotoxic/oxidative-effect biomarkers were assessed by the comet assay. Concentrations of total OHPAHs were up to 340% higher (p≤0.05) in (nonsmoking and smoking) exposed workers than in control subjects (non-smoking and non-exposed to combat activities); the highest increments were observed for 1-hydroxynaphthalene and 1-hydroxyacenaphthene (82–88% of ΣOHPAHs), and for 2-hydroxyfluorene (5–15%). Levels of biomarker for oxidative stress were increased in non-smoking exposed workers than in control group (316%; p≤0.001); inconclusive results were found for DNA damage. Positive correlations were found between the cardiac frequency, ΣOHPAHs and the oxidative DNA damage of non-smoking (non-exposed and exposed) firefighters. Evidences were raised regarding the simultaneous use of these biomarkers for the surveillance of firefighters’ health and to better estimate the potential short-term health risks.info:eu-repo/semantics/publishedVersio