X-ray and Radio Follow-up Observations of High-Redshift Blazar Candidates in the Fermi-LAT Unassociated Source Population

We report on the results of X-ray and radio follow-up observations of two GeV gamma-ray sources 2FGL J0923.5+1508 and 2FGL J1502.1+5548, selected as candidates for high-redshift blazars from unassociated sources in the {\it Fermi} Large Area Telescope Second Source Catalog. We utilize the Suzaku satellite and the VLBI Exploration of Radio Astrometry (VERA) telescopes for X-ray and radio observations, respectively. For 2FGL J0923.5+1508, a possible radio counterpart NVSS J092357+150518 is found at 1.4 GHz from an existing catalog, but we do not detect any X-ray emission from it and derive a flux upper limit $F_{\rm 2-8 keV} <$ 1.37 $\times$ 10$^{-14}$ erg cm$^{-2}$ s$^{-1}$. Radio observations at 6.7 GHz also result in an upper limit of $S_{\rm 6.7 GHz}$ $<$ 19 mJy, implying a steep radio spectrum that is not expected for a blazar. On the other hand, we detect X-rays from NVSS J150229+555204, the potential 1.4 GHz radio counterpart of 2FGL J1502.1+5548. The X-ray spectrum can be fitted with an absorbed power-law model with a photon index $\gamma$=1.8$^{+0.3}_{-0.2}$ and the unabsorbed flux is $F_{\rm 2-8 keV}$=4.3$^{+1.1}_{-1.0}$ $\times$ 10$^{-14}$ erg cm$^{-2}$ s$^{-1}$. Moreover, we detect unresolved radio emission at 6.7 GHz with flux $S_{\rm 6.7 GHz}$=30.1 mJy, indicating a compact, flat-spectrum radio source. If NVSS J150229+555204 is indeed associated with 2FGL J1502.1+5548, we find that its multiwavelength spectrum is consistent with a blazar at redshift $z \sim 3-4$.Comment: 24 pages, 7 figures, 6 tables, accepted for publication in Ap

Radio and gamma-ray follow-up of the exceptionally high activity state of PKS 1510-089 in 2011

We investigate the radio and gamma-ray variability of the flat spectrum radio quasar PKS 1510-089 in the time range between 2010 November and 2012 January. In this period the source showed an intense activity, with two major gamma-ray flares detected in 2011 July and October. During the latter episode both the gamma-ray and the radio flux density reached their historical peak. Multiwavelength analysis shows a rotation of about 380 deg of the optical polarization angle close in time with the rapid and strong gamma-ray flare in 2011 July. An enhancement of the optical emission and an increase of the fractional polarization both in the optical and in radio bands is observed about three weeks later, close in time with another gamma-ray outburst. On the other hand, after 2011 September a huge radio outburst has been detected, first in the millimeter regime followed with some time delay at centimeter down to decimeter wavelengths. This radio flare is characterized by a rising and a decaying stage, in agreement with the formation of a shock and its evolution, as a consequence of expansion and radiative cooling. If the gamma-ray flare observed in 2011 October is related to this radio outburst, then this strongly indicates that the region responsible for the gamma-ray variability is not within the broad line, but a few parsecs downstream along the jet.Comment: 14 pages, 12 figures, accepted for publication in MNRA

An automated archival VLA transients survey

In this paper we present the results of a survey for radio transients using data obtained from the Very Large Array archive. We have reduced, using a pipeline procedure, 5037 observations of the most common pointings - i.e. the calibrator fields. These fields typically contain a relatively bright point source and are used to calibrate `target' observations: they are therefore rarely imaged themselves. The observations used span a time range ~ 1984 - 2008 and consist of eight different pointings, three different frequencies (8.4, 4.8 and 1.4 GHz) and have a total observing time of 435 hours. We have searched for transient and variable radio sources within these observations using components from the prototype LOFAR transient detection system. In this paper we present the methodology for reducing large volumes of Very Large Array data; and we also present a brief overview of the prototype LOFAR transient detection algorithms. No radio transients were detected in this survey, therefore we place an upper limit on the snapshot rate of GHz frequency transients > 8.0 mJy to rho less than or equal to 0.032 deg^-2 that have typical timescales 4.3 to 45.3 days. We compare and contrast our upper limit with the snapshot rates - derived from either detections or non-detections of transient and variable radio sources - reported in the literature. When compared with the current Log N - Log S distribution formed from previous surveys, we show that our upper limit is consistent with the observed population. Current and future radio transient surveys will hopefully further constrain these statistics, and potentially discover dominant transient source populations. In this paper we also briefly explore the current transient commissioning observations with LOFAR, and the impact they will make on the field.Comment: Accepted for publication in MNRA

Possible Detection of Apparent Superluminal inward motion in Markarian 421 after the Giant X-ray flare in February, 2010

We report on the VLBI follow-up observations using the Japanese VLBI Network (JVN) array at 22 GHz for the largest X-ray flare of TeV blazar Mrk 421 that occurred in mid-February, 2010. The total of five epochs of observations were performed at intervals of about 20 days between March 7 and May 31, 2010. No new-born component associated with the flare was seen directly in the total intensity images obtained by our multi-epoch VLBI observations. However, one jet component located at ~1 mas north-west from the core was able to be identified, and its proper motion can be measured as -1.66+/-0.46 mas yr^-1, which corresponds to an apparent velocity of -3.48+/-0.97 c. Here, this negative velocity indicates that the jet component was apparently moving toward the core. As the most plausible explanation, we discuss that the apparent negative velocity was possibly caused by the ejection of a new component, which could not be resolved with our observations. In this case, the obtained Doppler factor of the new component is around 10 to 20, which is consistent with the ones typically estimated by model fittings of spectral energy distribution for this source.Comment: 9 pages, 6 figures, 3 tables, accepted for publication in Ap

A 22-year Southern Sky Survey for Transient and Variable Radio Sources using the Molonglo Observatory Synthesis Telescope

We describe a 22-year survey for variable and transient radio sources, performed with archival images taken with the Molonglo Observatory Synthesis Telescope (MOST). This survey covers 2775 \unit{deg^2} of the sky south of $\delta < -30\degree$ at an observing frequency of 843 MHz, an angular resolution of 45 \times 45 \csc | \delta| \unit{arcsec^2} and a sensitivity of 5 \sigma \geq 14 \unit{mJy beam^{-1}}. We describe a technique to compensate for image gain error, along with statistical techniques to check and classify variability in a population of light curves, with applicability to any image-based radio variability survey. Among radio light curves for almost 30000 sources, we present 53 highly variable sources and 15 transient sources. Only 3 of the transient sources, and none of the variable sources have been previously identified as transient or variable. Many of our variable sources are suspected scintillating Active Galactic Nuclei. We have identified three variable sources and one transient source that are likely to be associated with star forming galaxies at $z \simeq 0.05$, but whose implied luminosity is higher than the most luminous known radio supernova (SN1979C) by an order of magnitude. We also find a class of variable and transient source with no optical counterparts.Comment: Accepted for publication in MNRAS. 34 pages, 30 figures, 7 table

GCRT J1742-3001: A New Radio Transient Towards the Galactic Center

We report the detection of a new transient radio source, GCRT J1742-3001, located ~1 degree from the Galactic center. The source was detected ten times from late 2006 to 2007 May in our 235 MHz transient monitoring program with the Giant Metrewave Radio Telescope (GMRT). The radio emission brightened in about one month, reaching a peak observed flux density of ~100 mJy on 2007 January 28, and decaying to ~50 mJy by 2007 May when our last monitoring observation was made. Two additional faint, isolated 235 MHz detections were made in mid-2006, also with the GMRT. GCRT J1742-3001 is unresolved at each epoch, with typical resolutions of ~20 arcsec x 10 arcsec. No polarization information is available from the observations. Based on nondetections in observations obtained simultaneously at 610 MHz, we deduce that the spectrum of GCRT J1742-3001 is very steep, with a spectral index less than about -2. Follow-up radio observations in 2007 September at 330 MHz and 1.4 GHz, and in 2008 February at 235 MHz yielded no detections. No X-ray counterpart is detected in a serendipitous observation obtained with the X-ray telescope aboard the Swift satellite during the peak of the radio emission in early 2007. We consider the possibilities that GCRT J1742-3001 is either a new member of an existing class of radio transients, or is representative of a new class having no associated X-ray emission.Comment: 19 pages, 3 figures, submitted to Ap

Upregulation of AEBP1 in endothelial cells promotes tumor angiogenesis in colorectal cancer

血管新生は大腸がんの重要な治療標的である．本論文では，大腸がんの腫瘍血管関連遺伝子を探索し，AEBP1（Adipocyte enhancer binding protein 1）の血管内皮細胞における高発現を同定し，AEBP1が腫瘍血管新生促進に働くことを明らかにした

The almost ubiquitous association of 6.7 GHz methanol masers with dust

We report the results of 870-$\mu$m continuum observations, using the Large APEX Bolometer Camera (LABOCA), towards 77 class-II, 6.7-GHz methanol masers identified by the Methanol Multibeam (MMB) survey to map the thermal emission from cool dust towards these objects. These data complement a study of 630 methanol masers associated with compact dense clumps identified from the ATLASGAL survey. Compact dust emission is detected towards 70 sources, which implies a dust-association rate of 99% for the full MMB catalogue. Evaluation of the derived dust and maser properties leads us to conclude that the combined sample represents a single population tracing the same phenomenon. We find median clump masses of a few 10$^3$ M$\odot$ and that all but a handful of sources satisfy the mass-size criterion required for massive star formation. This study provides the strongest evidence of the almost ubiquitous association of methanol masers with massive, star-forming clumps. The fraction of methanol-maser associated clumps is a factor of ~2 lower in the outer Galaxy than the inner Galaxy, possibly a result of the lower metallicity environment of the former. We find no difference in the clump-mass and maser-luminosity distributions of the inner and outer Galaxy. The maser-pumping and clump-formation mechanisms are therefore likely to be relatively invariant to Galactic location. Finally, we use the ratio of maser luminosity and clump mass to investigate the hypothesis that the maser luminosity is a good indicator of the evolutionary stage of the embedded source, however, we find no evidence to support this.Comment: Accepted by MNRAS. 17 pages, 17 figures and 5 tables. The full version of Figs. 3 and 5 are only available in electronic form of the journal while the full versions of Tables 1, 2 and 4 will only be available through CDS. A complete version of the paper is available on reques