358 research outputs found
THE EFFECT OF OSTEOPOROSIS HEALTH EDUCATION PROGRAM BASED ON HEALTH BELIEF MODEL ON KNOWLEDGE AND HEALTH BELIEFS TOWARDS OSTEOPOROSIS AMONG JORDANIAN FEMALE TEACHERS
This study was conducted to assess the effect of osteoporosis health education program based on Health Belief Model on knowledge and health beliefs towards osteoporosis among Jordanian female teachers. This experimental study was performed on 200 female teachers (100 teachers in the intervention group and 100 in the control group) aged 25 - 49 years old in four governmental secondary schools affiliated to public educational directorate in Amman governorate. The females participated in a four-week educational program based on the Health Belief Model. The data collection instrument was a validated and reliable questionnaire in three sections: demographics, knowledge and health beliefs. The questionnaires on osteoporosis knowledge and health beliefs were given to the participants before the program (pre-intervention) and repeated three months later after the intervention on the same participants (post-intervention). The health education program prepared according to pre-intervention results. The results revealed that the mean scores of teachersâ knowledge and health beliefs subscales among the intervention group were significantly changed before and after the educational intervention program (P < 0.05). The use of an osteoporosis educational program seems to improve knowledge and health beliefs. In addition, it could support the need to raising the awareness and knowledge of osteoporosis
Hadronic vacuum polarization contribution to the anomalous magnetic moments of leptons from first principles
We compute the leading, strong-interaction contribution to the anomalous
magnetic moment of the electron, muon and tau using lattice quantum
chromodynamics (QCD) simulations. Calculations include the effects of , ,
and quarks and are performed directly at the physical values of the
quark masses and in volumes of linear extent larger than . All
connected and disconnected Wick contractions are calculated. Continuum limits
are carried out using six lattice spacings. We obtain
,
and
, where the first error
is statistical and the second is systematic.Comment: 17 pages, 8 figures (in 13 PDF files), RevTeX 4.1. Minor changes to
results and to text. References updated. Matches version published in
Physical Review Letter
Surface Production Fuels Deep Heterotrophic Respiration in Northern Peatlands
Multiple analyses of dissolved organic carbon (DOC) from pore waters were conducted to define the processes that govern carbon balance in peatlands: (1) source, reactivity, and transport of DOC with respect to vegetation, peat, and age of carbon substrate, (2) reactivity of DOC with respect to molecular size, and (3) lability to photoxidation of surficial DOC. We found that surface organic production fuels heterotrophic respiration at depth in advection-dominated peatlands, especially in fens. Fen DOC was Î14Cenriched relative to the surrounding fen peat, and fen respiration products were similar to this enriched DOC indicating that DOC was the main microbial substrate. Bog DOC was more variable showing either enrichment in Î14C at depth or Î14C values that follow peat values. This variability in bogs is probably controlled by the relative importance of vertical transport of labile carbon substrates within the peat profile versus DOC production from bog peat. These results extended our set of observations to 10 years at one bog-fen pair and add two additional bog-fen pairs to our series of observations. Anaerobic incubations of peat, rinsed free of residual DOC, produced DOC and respiration products that were strikingly similar to the peat values in a bog and two fens. This result demonstrated conclusively that downward advection is the process responsible for the presence of modern DOC found at depth in the peat column. Fen DOC has lower C/N values and up to twice as much LMW (kDa) DOC as bogs due to differences in organic inputs and greater microbial processing. Fluorescence irradiation experiments showed that fen DOC is more photolabile than bog DOC
Microwave observations of spinning dust emission in NGC6946
We report new cm-wave measurements at five frequencies between 15 and 18GHz
of the continuum emission from the reportedly anomalous "region 4" of the
nearby galaxy NGC6946. We find that the emission in this frequency range is
significantly in excess of that measured at 8.5GHz, but has a spectrum from
15-18GHz consistent with optically thin free-free emission from a compact HII
region. In combination with previously published data we fit four emission
models containing different continuum components using the Bayesian spectrum
analysis package radiospec. These fits show that, in combination with data at
other frequencies, a model with a spinning dust component is slightly preferred
to those that possess better-established emission mechanisms.Comment: submitted MNRA
High resolution AMI Large Array imaging of spinning dust sources: spatially correlated 8 micron emission and evidence of a stellar wind in L675
We present 25 arcsecond resolution radio images of five Lynds Dark Nebulae
(L675, L944, L1103, L1111 & L1246) at 16 GHz made with the Arcminute
Microkelvin Imager (AMI) Large Array. These objects were previously observed
with the AMI Small Array to have an excess of emission at microwave frequencies
relative to lower frequency radio data. In L675 we find a flat spectrum compact
radio counterpart to the 850 micron emission seen with SCUBA and suggest that
it is cm-wave emission from a previously unknown deeply embedded young
protostar. In the case of L1246 the cm-wave emission is spatially correlated
with 8 micron emission seen with Spitzer. Since the MIR emission is present
only in Spitzer band 4 we suggest that it arises from a population of PAH
molecules, which also give rise to the cm-wave emission through spinning dust
emission.Comment: accepted MNRA
CyberKnife radiosurgery for inoperable stage IA non-small cell lung cancer: 18F-fluorodeoxyglucose positron emission tomography/computed tomography serial tumor response assessment
Evidence that links loss of cyclooxygenase-2 with increased asymmetric dimethylarginine : novel explanation of cardiovascular side effects associated with anti-inflammatory drugs
© 2014 The Authors. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited.BACKGROUND: Cardiovascular side effects associated with cyclooxygenase-2 inhibitor drugs dominate clinical concern. Cyclooxygenase-2 is expressed in the renal medulla where inhibition causes fluid retention and increased blood pressure. However, the mechanisms linking cyclooxygenase-2 inhibition and cardiovascular events are unknown and no biomarkers have been identified.METHODS AND RESULTS: Transcriptome analysis of wild-type and cyclooxygenase-2(-/-) mouse tissues revealed 1 gene altered in the heart and aorta, but >1000 genes altered in the renal medulla, including those regulating the endogenous nitric oxide synthase inhibitors asymmetrical dimethylarginine (ADMA) and monomethyl-l-arginine. Cyclo-oxygenase-2(-/-) mice had increased plasma levels of ADMA and monomethyl-l-arginine and reduced endothelial nitric oxide responses. These genes and methylarginines were not similarly altered in mice lacking prostacyclin receptors. Wild-type mice or human volunteers taking cyclooxygenase-2 inhibitors also showed increased plasma ADMA. Endothelial nitric oxide is cardio-protective, reducing thrombosis and atherosclerosis. Consequently, increased ADMA is associated with cardiovascular disease. Thus, our study identifies ADMA as a biomarker and mechanistic bridge between renal cyclooxygenase-2 inhibition and systemic vascular dysfunction with nonsteroidal anti-inflammatory drug usage.CONCLUSIONS: We identify the endogenous endothelial nitric oxide synthase inhibitor ADMA as a biomarker and mechanistic bridge between renal cyclooxygenase-2 inhibition and systemic vascular dysfunction.Peer reviewedFinal Published versio
Interactions between Magnetic Nanowires and Living Cells : Uptake, Toxicity and Degradation
We report on the uptake, toxicity and degradation of magnetic nanowires by
NIH/3T3 mouse fibroblasts. Magnetic nanowires of diameters 200 nm and lengths
comprised between 1 {\mu}m and 40 {\mu}m are fabricated by controlled assembly
of iron oxide ({\gamma}-Fe2O3) nanoparticles. Using optical and electron
microscopy, we show that after 24 h incubation the wires are internalized by
the cells and located either in membrane-bound compartments or dispersed in the
cytosol. Using fluorescence microscopy, the membrane-bound compartments were
identified as late endosomal/lysosomal endosomes labeled with lysosomal
associated membrane protein (Lamp1). Toxicity assays evaluating the
mitochondrial activity, cell proliferation and production of reactive oxygen
species show that the wires do not display acute short-term (< 100 h) toxicity
towards the cells. Interestingly, the cells are able to degrade the wires and
to transform them into smaller aggregates, even in short time periods (days).
This degradation is likely to occur as a consequence of the internal structure
of the wires, which is that of a non-covalently bound aggregate. We anticipate
that this degradation should prevent long-term asbestos-like toxicity effects
related to high aspect ratio morphologies and that these wires represent a
promising class of nanomaterials for cell manipulation and microrheology.Comment: 21 pages 12 figure
Bayesian analysis of weak gravitational lensing and Sunyaev-Zel'dovich data for six galaxy clusters
We present an analysis of observations made with the Arcminute Microkelvin
Imager (AMI) and the Canada-France-Hawaii Telescope (CFHT) of six galaxy
clusters in a redshift range of 0.16--0.41. The cluster gas is modelled using
the Sunyaev--Zel'dovich (SZ) data provided by AMI, while the total mass is
modelled using the lensing data from the CFHT. In this paper, we: i) find very
good agreement between SZ measurements (assuming large-scale virialisation and
a gas-fraction prior) and lensing measurements of the total cluster masses out
to r_200; ii) perform the first multiple-component weak-lensing analysis of
A115; iii) confirm the unusual separation between the gas and mass components
in A1914; iv) jointly analyse the SZ and lensing data for the relaxed cluster
A611, confirming our use of a simulation-derived mass-temperature relation for
parameterizing measurements of the SZ effect.Comment: 22 pages, 12 figures, 12 tables, published by MNRA
Living between languages: The politics of translation in Leila Aboulelaâs Minaret and Xiaolu Guoâs A Concise Chinese-English Dictionary for Lovers
This is the author's final draft post-refereeing as published in The Journal of Commonwealth Literature 2012 47: 207 DOI:10.1177/0021989412440433. The online version of this article can be found at: http://jcl.sagepub.com/content/47/2/20
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