Field-Assisted and Thermionic Contributions to Conductance in SnO2 Thick-Films

A deep analysis of conductance in nanostructured SnO2 thick films has been performed. A model for field-assisted thermionic barrier crossing is being proposed to explain the film conductivity. Themodel has been applied to explain the behavior of resistance in vacuum of two sets of nanostructured thick-films with grains having two well-distinct characteristic radii (R = 25nm and R = 125 nm). In the first case the grain radius is shorter than the depletion region width, a limit at which overlapping of barriers takes place, and in the second case it is longer. The behavior of resistance in the presence of dry air has been explained through the mechanism of barrier modulation through gas chemisorption.Fil: Malagú, C.. Universita Di Ferrara; ItaliaFil: Carotta, M. Cristina. Universita Di Ferrara; ItaliaFil: Martinelli, Giuliano. Universita Di Ferrara; ItaliaFil: Ponce, Miguel Adolfo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; ArgentinaFil: Castro, Miriam Susana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; ArgentinaFil: Aldao, Celso Manuel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; Argentin

Revisión del género Pseudognaphalium (Asteraceae, Gnaphalieae) en Chile

The genus Pseudognaphalium is one of the largest genera of the tribe Gnaphalieae (Asteraceae) with about 90 species with worldwide distribution. The vast majority of species are found in South, Central and North America, but some species also occur in Asia and Africa. This work includes the revision of 12 species of Pseudognaphalium from Chile, P. aldunateoides, P. cabrerae, P. cheiranthifolium, P. cymatoides, P. gayanum, P. lacteum, P. landbeckii, P. munoziae, P. psilophyllum, P. remyanum, P. tarapacanum, and P. viravira. A key is provided for their identification, as well as morphological description, illustration, geographic distribution and habitat, distribution maps, phenology, additional material examined, distinguishing characters and taxonomic affinities for each taxon. The new combination Pseudognaphalium cabrerae (S.E. Freire) S.E. Freire, N. Bayón, C. Baeza, Giuliano & C. Monti, is proposed. The following taxa are newly synonymized: Gnaphalium diminutivum, Pseudognaphalium perpusillum, with P. aldunateoides; G. canum, G. ulophyllum, P. moelleri with P. cymatoides; P. heterophyllum, P. heterotrichum, G. pseudohelichrysum, P. robustum with P. gayanum; P. glandulosum with P. psilophyllum; G. longifolium, G. subnudum, P. andicola, P. coquimbense, P. illapelinum, P. montevidense, P. pratense, with P. viravira. Lectotypes are newly designated for Gnaphalium acutifolium, G. araucanum, G. argyrolepis, G. canum, G. cymatoides, G. glandulosum, G. heterophyllum, G. illapelinum, G. lacteum, G. landbeckii, G. moelleri, G. ramosum, G. remyanum, G. subnudum, G. tarapacanum, G. ulophyllum, and G. viravira. A neotype is designated for G. psilophyllum.El género Pseudognaphalium, con cerca de 90 especies de distribución cosmopolita, es uno de los géneros de la tribu Gnaphalieae con mayor número de especies, principalmente distribuidas en América del Sur, Central y del Norte, aunque algunas también están presentes en Asia y África. Este trabajo comprende la revisión de 12 especies de Pseudognaphalium para Chile, P. aldunateoides, P. cabrerae, P. cheiranthifolium, P. cymatoides, P. gayanum, P. lacteum, P. landbeckii, P. munoziae, P. psilophyllum, P. remyanum, P. tarapacanum y P. viravira. Se incluye una clave para identificarlas y para cada una de las especies se brinda descripción, ilustración, fenología, distribución geográfica y hábitat, mapa de distribución, material adicional examinado y afinidades taxonómicas. Sobre la base del estudio de los materiales tipo, se establecen los siguientes nuevos sinónimos: Gnaphalium diminutivum, Pseudognaphalium perpusillum, con P. aldunateoides; G. canum, G. ulophyllum, P. moelleri con P. cymatoides; P. heterophyllum, P. heterotrichum, G. pseudohelichrysum, P. robustum, con P. gayanum; P. glandulosum con P. psilophyllum; G. longifolium, G. subnudum, P. andicola, P. coquimbense, P. illapelinum, P. montevidense, P. pratense, con P. viravira; se designan lectotipos para las siguientes especies: Gnaphalium acutifolium, G. araucanum, G. argyrolepis, G. canum, G. cymatoides, G. glandulosum, G. heterophyllum, G. illapelinum, G. lacteum, G. landbeckii, G. moelleri, G. ramosum, G. remyanum, G. subnudum, G. tarapacanum, G. ulophyllum, G. viravira y se designa el neotipo para G. psilophyllum.Facultad de Ciencias Agrarias y Forestale

Comparison of washing methods and smear conservation periods for llama sperm acrosome assessment using the Coomassie blue stain

El objetivo de este trabajo fue comparar métodos de lavado y conservación de frotis para evaluar el acrosoma en espermatozoides de llama mediante la tinción con Coomassie Blue (CB), con el propósito de facilitar la técnica e independizar los momentos de la extracción de semen de la evaluación de los acrosomas espermáticos. Se procesaron 12 eyaculados, se probaron dos tipos de lavado de los frotis fijados (con PBS o solución fisiológica, SF) y se evaluaron diferentes temperaturas (5º C y temperatura ambiente) y tiempos (0, 1 y 7 días) de conservación. Se evaluaron los siguientes frotis (cada uno lavado con PBS o con SF): 1) fijados, teñidos y evaluados el mismo día de la extracción; 2) fijados, teñidos y conservados 24 hs a temperatura ambiente y luego evaluados; 3) fijados, conservados a 4º C durante 1 día y luego teñidos y evaluados; 4) fijados, conservados a 4º C durante 7 días y luego teñidos y evaluados. Se evaluaron un total de 8 frotis por eyaculado. No se observaron diferencias significativas en el porcentaje de acrosomas presentes evaluado por CB entre las dos metodologías de lavado de los frotis fijados, ni entre las diferentes temperaturas y los diferentes tiempos de conservación de los frotis. Conclusión: es posible utilizar solución fisiológica para lavar los frotis fijados facilitando la técnica de CB para evaluar la presencia de los acrosomas en espermatozoides de llama. Además, se logró independizar los momentos de la extracción de semen de la evaluación de los acrosomas espermáticos.The objective of this study was to compare washing methods and smear conservation periods for llama sperm acrosome assessment using the Coomassie Blue stain, with the aim of facilitating the technique and to allow the moment of sperm acrosome evaluation become independent of the moment of semen collection. Twelve ejaculates were processed; two types of washing of the smears (with PBS or with physiologic solution, PS) and different temperatures (5 ºC and room temperature) and periods of conservation (0, 1 and 7 days) were assessed. The following smears were evaluated: 1) fixed, stained and evaluated the same day of collection; 2) fixed, stained and conserved for 24 hours at room temperature and then evaluated; 3) fixed, conserved at 4º C for 1 day and then stained and evaluated and 4) fixed, conserved at 4º C for 7 days and then stained and evaluated. A total of 8 smears per ejaculate were evaluated. No significant differences were observed in the percentages of acrosomes present, evaluated by CB, between both types of washing of the fixed smears, nor between the different temperatures and conservation periods of the fixed smears. Conclusions: it is possible to use physiologic solution to wash the fixed smears, thus facilitating the Coomassie Blue technique used to evaluate the presence of llama sperm acrosomes. In addition, it was possible to separate the moment of sperm acrosome evaluation from the semen collection.Fil: Fumuso, Fernanda Gabriela. Universidad de Buenos Aires. Facultad de Cs.veterinarias. Area de Teriogenologia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Gimenez, M. L.. Universidad de Buenos Aires. Facultad de Cs.veterinarias. Area de Teriogenologia; ArgentinaFil: Neild, Debora Margarita. Universidad de Buenos Aires. Facultad de Cs.veterinarias. Area de Teriogenologia; ArgentinaFil: Giuliano, Susana María. Universidad de Buenos Aires. Facultad de Cs.veterinarias. Area de Teriogenologia; ArgentinaFil: Chaves, M. G.. Universidad de Buenos Aires. Facultad de Cs.veterinarias. Area de Teriogenologia; ArgentinaFil: Carretero, Maria Ignacia. Universidad de Buenos Aires. Facultad de Cs.veterinarias. Area de Teriogenologia; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

Revisión del género Pseudognaphalium (Asteraceae, Gnaphalieae) en Chile

The genus Pseudognaphalium is one of the largest genera of the tribe Gnaphalieae (Asteraceae) with about 90 species with worldwide distribution. The vast majority of species are found in South, Central and North America, but some species also occur in Asia and Africa. This work includes the revision of 12 species of Pseudognaphalium from Chile, P. aldunateoides, P. cabrerae, P. cheiranthifolium, P. cymatoides, P. gayanum, P. lacteum, P. landbeckii, P. munoziae, P. psilophyllum, P. remyanum, P. tarapacanum, and P. viravira. A key is provided for their identification, as well as morphological description, illustration, geographic distribution and habitat, distribution maps, phenology, additional material examined, distinguishing characters and taxonomic affinities for each taxon. The new combination Pseudognaphalium cabrerae (S.E. Freire) S.E. Freire, N. Bayón, C. Baeza, Giuliano & C. Monti, is proposed. The following taxa are newly synonymized: Gnaphalium diminutivum, Pseudognaphalium perpusillum, with P. aldunateoides; G. canum, G. ulophyllum, P. moelleri with P. cymatoides; P. heterophyllum, P. heterotrichum, G. pseudohelichrysum, P. robustum with P. gayanum; P. glandulosum with P. psilophyllum; G. longifolium, G. subnudum, P. andicola, P. coquimbense, P. illapelinum, P. montevidense, P. pratense, with P. viravira. Lectotypes are newly designated for Gnaphalium acutifolium, G. araucanum, G. argyrolepis, G. canum, G. cymatoides, G. glandulosum, G. heterophyllum, G. illapelinum, G. lacteum, G. landbeckii, G. moelleri, G. ramosum, G. remyanum, G. subnudum, G. tarapacanum, G. ulophyllum, and G. viravira. A neotype is designated for G. psilophyllum.El género Pseudognaphalium, con cerca de 90 especies de distribución cosmopolita, es uno de los géneros de la tribu Gnaphalieae con mayor número de especies, principalmente distribuidas en América del Sur, Central y del Norte, aunque algunas también están presentes en Asia y África. Este trabajo comprende la revisión de 12 especies de Pseudognaphalium para Chile, P. aldunateoides, P. cabrerae, P. cheiranthifolium, P. cymatoides, P. gayanum, P. lacteum, P. landbeckii, P. munoziae, P. psilophyllum, P. remyanum, P. tarapacanum y P. viravira. Se incluye una clave para identificarlas y para cada una de las especies se brinda descripción, ilustración, fenología, distribución geográfica y hábitat, mapa de distribución, material adicional examinado y afinidades taxonómicas. Sobre la base del estudio de los materiales tipo, se establecen los siguientes nuevos sinónimos: Gnaphalium diminutivum, Pseudognaphalium perpusillum, con P. aldunateoides; G. canum, G. ulophyllum, P. moelleri con P. cymatoides; P. heterophyllum, P. heterotrichum, G. pseudohelichrysum, P. robustum, con P. gayanum; P. glandulosum con P. psilophyllum; G. longifolium, G. subnudum, P. andicola, P. coquimbense, P. illapelinum, P. montevidense, P. pratense, con P. viravira; se designan lectotipos para las siguientes especies: Gnaphalium acutifolium, G. araucanum, G. argyrolepis, G. canum, G. cymatoides, G. glandulosum, G. heterophyllum, G. illapelinum, G. lacteum, G. landbeckii, G. moelleri, G. ramosum, G. remyanum, G. subnudum, G. tarapacanum, G. ulophyllum, G. viravira y se designa el neotipo para G. psilophyllum.Facultad de Ciencias Agrarias y Forestale

Revisión del género Pseudognaphalium (Asteraceae, Gnaphalieae) en Chile

The genus Pseudognaphalium is one of the largest genera of the tribe Gnaphalieae (Asteraceae) with about 90 species with worldwide distribution. The vast majority of species are found in South, Central and North America, but some species also occur in Asia and Africa. This work includes the revision of 12 species of Pseudognaphalium from Chile, P. aldunateoides, P. cabrerae, P. cheiranthifolium, P. cymatoides, P. gayanum, P. lacteum, P. landbeckii, P. munoziae, P. psilophyllum, P. remyanum, P. tarapacanum, and P. viravira. A key is provided for their identification, as well as morphological description, illustration, geographic distribution and habitat, distribution maps, phenology, additional material examined, distinguishing characters and taxonomic affinities for each taxon. The new combination Pseudognaphalium cabrerae (S.E. Freire) S.E. Freire, N. Bayón, C. Baeza, Giuliano & C. Monti, is proposed. The following taxa are newly synonymized: Gnaphalium diminutivum, Pseudognaphalium perpusillum, with P. aldunateoides; G. canum, G. ulophyllum, P. moelleri with P. cymatoides; P. heterophyllum, P. heterotrichum, G. pseudohelichrysum, P. robustum with P. gayanum; P. glandulosum with P. psilophyllum; G. longifolium, G. subnudum, P. andicola, P. coquimbense, P. illapelinum, P. montevidense, P. pratense, with P. viravira. Lectotypes are newly designated for Gnaphalium acutifolium, G. araucanum, G. argyrolepis, G. canum, G. cymatoides, G. glandulosum, G. heterophyllum, G. illapelinum, G. lacteum, G. landbeckii, G. moelleri, G. ramosum, G. remyanum, G. subnudum, G. tarapacanum, G. ulophyllum, and G. viravira. A neotype is designated for G. psilophyllum.El género Pseudognaphalium, con cerca de 90 especies de distribución cosmopolita, es uno de los géneros de la tribu Gnaphalieae con mayor número de especies, principalmente distribuidas en América del Sur, Central y del Norte, aunque algunas también están presentes en Asia y África. Este trabajo comprende la revisión de 12 especies de Pseudognaphalium para Chile, P. aldunateoides, P. cabrerae, P. cheiranthifolium, P. cymatoides, P. gayanum, P. lacteum, P. landbeckii, P. munoziae, P. psilophyllum, P. remyanum, P. tarapacanum y P. viravira. Se incluye una clave para identificarlas y para cada una de las especies se brinda descripción, ilustración, fenología, distribución geográfica y hábitat, mapa de distribución, material adicional examinado y afinidades taxonómicas. Sobre la base del estudio de los materiales tipo, se establecen los siguientes nuevos sinónimos: Gnaphalium diminutivum, Pseudognaphalium perpusillum, con P. aldunateoides; G. canum, G. ulophyllum, P. moelleri con P. cymatoides; P. heterophyllum, P. heterotrichum, G. pseudohelichrysum, P. robustum, con P. gayanum; P. glandulosum con P. psilophyllum; G. longifolium, G. subnudum, P. andicola, P. coquimbense, P. illapelinum, P. montevidense, P. pratense, con P. viravira; se designan lectotipos para las siguientes especies: Gnaphalium acutifolium, G. araucanum, G. argyrolepis, G. canum, G. cymatoides, G. glandulosum, G. heterophyllum, G. illapelinum, G. lacteum, G. landbeckii, G. moelleri, G. ramosum, G. remyanum, G. subnudum, G. tarapacanum, G. ulophyllum, G. viravira y se designa el neotipo para G. psilophyllum

Physical Exercise and Alzheimer's Disease: Effects on Pathophysiological Molecular Pathways of the Disease

Alzheimer's disease (AD), the most common form of neurodegenerative dementia in adults worldwide, is a multifactorial and heterogeneous disorder characterized by the interaction of genetic and epigenetic factors and the dysregulation of numerous intracellular signaling and cellular/molecular pathways. The introduction of the systems biology framework is revolutionizing the study of complex diseases by allowing the identification and integration of cellular/molecular pathways and networks of interaction. Here, we reviewed the relationship between physical activity and the next pathophysiological processes involved in the risk of developing AD, based on some crucial molecular pathways and biological process dysregulated in AD: (1) Immune system and inflammation; (2) Endothelial function and cerebrovascular insufficiency; (3) Apoptosis and cell death; (4) Intercellular communication; (5) Metabolism, oxidative stress and neurotoxicity; (6) DNA damage and repair; (7) Cytoskeleton and membrane proteins; (8) Synaptic plasticity. Moreover, we highlighted the increasingly relevant role played by advanced neuroimaging technologies, including structural/functional magnetic resonance imaging, diffusion tensor imaging, and arterial spin labelling, in exploring the link between AD and physical exercise. Regular physical exercise seems to have a protective effect against AD by inhibiting different pathophysiological molecular pathways implicated in AD

Phylogenetic and Metabolic Tracking of Gut Microbiota during Perinatal Development

The colonization and development of gut microbiota immediately after birth is highly variable and depends on several factors, such as delivery mode and modality of feeding during the first months of life. A cohort of 31 mother and neonate pairs, including 25 at-term caesarean (CS) and 6 vaginally (V) delivered neonates (DNs), were included in this study and 121 meconium/faecal samples were collected at days 1 through 30 following birth. Operational taxonomic units (OTUs) were assessed in 69 stool samples by phylogenetic microarray HITChip and inter- and intra-individual distributions were established by inter-OTUs correlation matrices and OTUs co-occurrence or co-exclusion networks. H-1-NMR metabolites were determined in 70 stool samples, PCA analysis was performed on 55 CS DNs samples, and metabolome/OTUs co-correlations were assessed in 45 CS samples, providing an integrated map of the early microbiota OTUs-metabolome. A microbiota "core" of OTUs was identified that was independent of delivery mode and lactation stage, suggesting highly specialized communities that act as seminal colonizers of microbial networks. Correlations among OTUs, metabolites, and OTUs-metabolites revealed metabolic profiles associated with early microbial ecological dynamics, maturation of milk components, and host physiology.Peer reviewe

Concepts for the Development of Person-Centered, Digitally Enabled, Artificial Intelligence–Assisted ARIA Care Pathways (ARIA 2024)

Funding Information: This work has received funding from ARIA (Allergic Rhinitis and its Impact of Asthma); CATALYSE (Climate Action To Advance HeaLthY Societies in Europe), the European Union\u2019s Horizon Europe research and innovation program under grant agreement no. 101057131; FRAUNHOFER Institute for Translational Medicine and Pharmacology (ITMP), Immunology and Allergology, Berlin, Germany; University of Porto, Portugal; and MASK-air, which has been supported by EU grants (Impact of air Pollution on Asthma and Rhinitis [POLLAR] project of the European Institute of Innovation and Technology Health; Structural and Development Funds, R\u00E9gion Languedoc Roussillon and Provence-Alpes-C\u00F4te d\u2019Azur; Twinning, European Innovation Partnership on Active and Healthy Ageing, DG Sant\u00E9 and DG Connect); educational grants from Mylan-Viatris, Allergologisk Laboratorium K\u00F8benhavn, GlaxoSmithKline, Novartis, Stallerg\u00E8nes-Greer, and Noucor; and funding from Breathing Together Onlus Association (Associazione Respiriamo Insieme Onlus), Italy; Esp\u00EDritu Santo University, Samborond\u00F3n, Ecuador; Finnish Anti-Tuberculosis Association Foundation and Tampere Tuberculosis Foundation; GA 2 LEN; German Allergy Society AeDA (\u00C4rzteverband Deutscher Allergologen); IPOKRaTES (International Postgraduate Organization for Knowledge transfer, Research and Teaching Excellent Students) Lithuania Fund; Polish Society of Allergology (POLSKIE TOWARZYSTWO ALLERGOLOGICZNE); and University of Li\u00E8ge, Belgium. Funding Information: Conflicts of interest: J. Bousquet reports personal fees from Cipla, Menarini, Mylan, Novartis, Purina, Sanofi-Aventis, Teva, Noucor, other from KYomed-Innov, and other from Mask-air-SAS, outside the submitted work. M. Blaiss reports personal fees from Sanofi, personal fees from Regeneron, personal fees from ALK, personal fees from Merck, personal fees from AstraZeneca, personal fees from GSK, personal fees from Prollergy, personal fees from Lanier Biotherapeutics, and nonfinancial support from Bryn Phama, outside the submitted work. J. Lity\u0144ska reports personal fees from Evidence Prime Sp. z o.o., outside the submitted work. T. Iinuma reports grants from Sanofi, outside the submitted work. P. Tantilipikorn reports grants from Abbott, other from GSK, and other from Sanofi Aventis, outside the submitted work. T. Haahtela reports personal fees from Orion Pharma, outside the submitted work. Publisher Copyright: © 2024 The AuthorsThe traditional healthcare model is focused on diseases (medicine and natural science) and does not acknowledge patients’ resources and abilities to be experts in their own lives based on their lived experiences. Improving healthcare safety, quality, and coordination, as well as quality of life, is an important aim in the care of patients with chronic conditions. Person-centered care needs to ensure that people's values and preferences guide clinical decisions. This paper reviews current knowledge to develop (1) digital care pathways for rhinitis and asthma multimorbidity and (2) digitally enabled, person-centered care.1 It combines all relevant research evidence, including the so-called real-world evidence, with the ultimate goal to develop digitally enabled, patient-centered care. The paper includes (1) Allergic Rhinitis and its Impact on Asthma (ARIA), a 2-decade journey, (2) Grading of Recommendations, Assessment, Development and Evaluation (GRADE), the evidence-based model of guidelines in airway diseases, (3) mHealth impact on airway diseases, (4) From guidelines to digital care pathways, (5) Embedding Planetary Health, (6) Novel classification of rhinitis and asthma, (7) Embedding real-life data with population-based studies, (8) The ARIA-EAACI (European Academy of Allergy and Clinical Immunology) strategy for the management of airway diseases using digital biomarkers, (9) Artificial intelligence, (10) The development of digitally enabled, ARIA person-centered care, and (11) The political agenda. The ultimate goal is to propose ARIA 2024 guidelines centered around the patient to make them more applicable and sustainable.proofinpres

The James Webb Space Telescope Mission

Twenty-six years ago a small committee report, building on earlier studies, expounded a compelling and poetic vision for the future of astronomy, calling for an infrared-optimized space telescope with an aperture of at least $4m$. With the support of their governments in the US, Europe, and Canada, 20,000 people realized that vision as the $6.5m$ James Webb Space Telescope. A generation of astronomers will celebrate their accomplishments for the life of the mission, potentially as long as 20 years, and beyond. This report and the scientific discoveries that follow are extended thank-you notes to the 20,000 team members. The telescope is working perfectly, with much better image quality than expected. In this and accompanying papers, we give a brief history, describe the observatory, outline its objectives and current observing program, and discuss the inventions and people who made it possible. We cite detailed reports on the design and the measured performance on orbit.Comment: Accepted by PASP for the special issue on The James Webb Space Telescope Overview, 29 pages, 4 figure

Cabbage and fermented vegetables : From death rate heterogeneity in countries to candidates for mitigation strategies of severe COVID-19

Large differences in COVID-19 death rates exist between countries and between regions of the same country. Some very low death rate countries such as Eastern Asia, Central Europe, or the Balkans have a common feature of eating large quantities of fermented foods. Although biases exist when examining ecological studies, fermented vegetables or cabbage have been associated with low death rates in European countries. SARS-CoV-2 binds to its receptor, the angiotensin-converting enzyme 2 (ACE2). As a result of SARS-CoV-2 binding, ACE2 downregulation enhances the angiotensin II receptor type 1 (AT(1)R) axis associated with oxidative stress. This leads to insulin resistance as well as lung and endothelial damage, two severe outcomes of COVID-19. The nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is the most potent antioxidant in humans and can block in particular the AT(1)R axis. Cabbage contains precursors of sulforaphane, the most active natural activator of Nrf2. Fermented vegetables contain many lactobacilli, which are also potent Nrf2 activators. Three examples are: kimchi in Korea, westernized foods, and the slum paradox. It is proposed that fermented cabbage is a proof-of-concept of dietary manipulations that may enhance Nrf2-associated antioxidant effects, helpful in mitigating COVID-19 severity.Peer reviewe