1,825 research outputs found
The Rise of a New Mental Health Epidemic: TikTok and Social Media, and Their Negative Impact on Young Adults
The effects of TikTok and social media are explored to understand how detrimental social networking sites are to one\u27s mental health. The research and literature show how the overuse of social media contributes to social media addiction, mental health issues, body dysmorphia, and cyberbullying. A study is analyzed that reports how many are affected by cyberbullying and whether they received counseling for their mental health. It was concluded that social media does much more harm than good, and users could try altering their lives by reducing the amount of time spent on social networking sites
Setting the Mood: Background Color and Guppy Mate Choice
▪ There are two prevalent forms of sexual selection in the animals:Male-Male Competition and Female Choice
▪ Guppies (Poecilia reticulata) have been shown to demonstrate Female Choice
▪ Environmental factors, such as background color, have been shown to affect female interest in specific males
▪ Guppies tend to show interest in the color orange and we predicted that females would show a preference for males on an orange backgroun
Improving Cardiology Patient Flow In Nuclear Medicine
At baseline, a nuclear medicine department found it difficult to complete cardiac stress tests within scheduled times. Using the performance improvement process, a nuclear medicine department looked to improve patient experience related to wait times for this test.
Two goals were identified and a root cause analysis was initiated. After identifying some process issues, two KPIs were developed to address them.
A root cause analysis identified some processing issues and two KPIs were instituted to address them.
As a result, one outcome was to hire an additional physician assistant to address the barrier of inadequate cardiology coverage. Next steps include continued auditing of delays to discern what other barriers might exist to completing cardiac stress tests in the scheduled time frame
Longitudinal dynamics of skin bacterial communities in the context of Staphylococcus aureus decolonization
Decolonization with topical antimicrobials is frequently prescribed in health care and community settings to prevent Staphylococcus aureus infection. However, effects on commensal skin microbial communities remains largely unexplored. Within a household affected by recurrent methicillin-resistant S. aureus skin and soft tissue infections (SSTI), skin swabs were collected from the anterior nares, axillae, and inguinal folds of 14 participants at 1- to 3-month intervals over 24 months. Four household members experienced SSTI during the first 12-months (observational period) and were prescribed a 5-day decolonization regimen with intranasal mupirocin and bleach water baths at the 12-month study visit. We sequenced the 16S rRNA gene V1-V2 region and compared bacterial community characteristics between the pre- and post-intervention periods and between younger and older subjects. The median Shannon diversity index was stable during the 12-month observational period at all three body sites. Bacterial community characteristics (diversity, stability, and taxonomic composition) varied with age. Among all household members, not exclusively among the four performing decolonization, diversity was unstable throughout the year post-intervention. In the month after decolonization, bacterial communities were changed. Although communities largely returned to their baseline states, relative abundance of some taxa remained changed throughout the year following decolonization (e.g., more abundan
The Grizzly, April 28, 2011
New U Hosts Spring Into Wellness Month • College Campuses are a Hotbed for Theft • Take a Little Break with Activities from Around Collegeville • Relay for Life Benefits American Cancer Society • Active Minds Hosts Art Festival • Senior Reflection: The Past was Worth the Future • Students Uncover Papers from the Third Reich • Internship Spotlight: Sierra Guerin • Opinions: The Magic is in the Turning of the Page; Books and Electronic Books can Coexist; A New (Satirical) Take on Racial (In)equality at Ursinus • Looking Past Senioritis: Importance of Giving Back to UC • Senior Spotlight: Runner Jeremy Garavelhttps://digitalcommons.ursinus.edu/grizzlynews/1836/thumbnail.jp
Individual size, sex and rearing environment impact on aggression in newly weaned seals
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Volume 12
Introduction, Dr. Roger A. Byrne, Dean
From the Editor, Dr. Larissa Kat Tracy
From the Designers, Rachel English, Rachel Hanson
Immortality in the Mortal World: Otherworldly Intervention in Lanval and The Wife of Bath\u27s Tale by Haleigh James
Analysis of Phenolic Compounds in Moroccan Olive Oils by HPLC by Hannah Meyls
Art by Hope Irvin
The Effects of Cell Phone Use on Gameplay Enjoyment and Frustration by Megan E. Hlavaty, Samara L. Gall, and Austin J. Funk
Care, No Matter What: Planned Parenthood\u27s Use of Organizational Rhetoric to Expand its Reputation by Karyn Keane
Analysis of Petroleum Products for Forensic and Environmental Applications by Sarah Ghali, Antonio Harvey, and Katelynn McCrillis
Art by Andrew Jones
The Triangle Shirtwaist Factory Fire by Rachel Hazelwood
Art by Madison Schmitz
Ercilla y la imitacion: Araucanos al estilo europeo by Marija Venta
Design by Haley Tebo
Design by Jeremiah Gilmer
White Supremacist\u27s Appropriation of the Persuasion of Passivity in Marvel\u27s Captain America by Bridget Dunn
Design by Benjamin Sullivan
Art by McKenzie Johnso
Recent research on Gulf War illness and other health problems in veterans of the 1991 Gulf War: Effects of toxicant exposures during deployment
Veterans of Operation Desert Storm/Desert Shield - the 1991 Gulf War (GW) - are a unique population who returned from theater with multiple health complaints and disorders. Studies in the U.S. and elsewhere have consistently concluded that approximately 25-32% of this population suffers from a disorder characterized by symptoms that vary somewhat among individuals and include fatigue, headaches, cognitive dysfunction, musculoskeletal pain, and respiratory, gastrointestinal and dermatologic complaints. Gulf War illness (GWI) is the term used to describe this disorder. In addition, brain cancer occurs at increased rates in subgroups of GW veterans, as do neuropsychological and brain imaging abnormalities. Chemical exposures have become the focus of etiologic GWI research because nervous system symptoms are prominent and many neurotoxicants were present in theater, including organophosphates (OPs), carbamates, and other pesticides; sarin/cyclosarin nerve agents, and pyridostigmine bromide (PB) medications used as prophylaxis against chemical warfare attacks. Psychiatric etiologies have been ruled out. This paper reviews the recent literature on the health of 1991 GW veterans, focusing particularly on the central nervous system and on effects of toxicant exposures. In addition, it emphasizes research published since 2008, following on an exhaustive review that was published in that year that summarizes the prior literature (RACGWI, 2008). We conclude that exposure to pesticides and/or to PB are causally associated with GWI and the neurological dysfunction in GW veterans. Exposure to sarin and cyclosarin and to oil well fire emissions are also associated with neurologically based health effects, though their contribution to development of the disorder known as GWI is less clear. Gene-environment interactions are likely to have contributed to development of GWI in deployed veterans. The health consequences of chemical exposures in the GW and other conflicts have been called "toxic wounds" by veterans. This type of injury requires further study and concentrated treatment research efforts that may also benefit other occupational groups with similar exposure-related illnesses
A Combined Pathway and Regional Heritability Analysis Indicates NETRIN1 Pathway is Associated with Major Depressive Disorder
AbstractBackgroundGenome-wide association studies (GWASs) of major depressive disorder (MDD) have identified few significant associations. Testing the aggregation of genetic variants, in particular biological pathways, may be more powerful. Regional heritability analysis can be used to detect genomic regions that contribute to disease risk.MethodsWe integrated pathway analysis and multilevel regional heritability analyses in a pipeline designed to identify MDD-associated pathways. The pipeline was applied to two independent GWAS samples [Generation Scotland: The Scottish Family Health Study (GS:SFHS, N = 6455) and Psychiatric Genomics Consortium (PGC:MDD) (N = 18,759)]. A polygenic risk score (PRS) composed of single nucleotide polymorphisms from the pathway most consistently associated with MDD was created, and its accuracy to predict MDD, using area under the curve, logistic regression, and linear mixed model analyses, was tested.ResultsIn GS:SFHS, four pathways were significantly associated with MDD, and two of these explained a significant amount of pathway-level regional heritability. In PGC:MDD, one pathway was significantly associated with MDD. Pathway-level regional heritability was significant in this pathway in one subset of PGC:MDD. For both samples the regional heritabilities were further localized to the gene and subregion levels. The NETRIN1 signaling pathway showed the most consistent association with MDD across the two samples. PRSs from this pathway showed competitive predictive accuracy compared with the whole-genome PRSs when using area under the curve statistics, logistic regression, and linear mixed model.ConclusionsThese post-GWAS analyses highlight the value of combining multiple methods on multiple GWAS data for the identification of risk pathways for MDD. The NETRIN1 signaling pathway is identified as a candidate pathway for MDD and should be explored in further large population studies
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