727 research outputs found
Applying Revenue Management to the Reverse Supply Chain
We study the disposition decision for product returns in a closed-loop supply chain. Motivated by the asset recovery process at IBM, we consider two disposition alternatives. Returns may be either refurbished for reselling or dismantled for spare parts. Reselling a refurbished unit typically yields higher unit margins. However, demand is uncertain. A common policy in many firms is to rank disposition alternatives by unit margins. We show that a revenue management approach to the disposition decision which explicitly incorporates demand uncertainty can increase profits significantly. We discuss analogies between the disposition problem and the classical airline revenue management problem. We then develop single period and multi-period stochastic optimization models for the disposition problem. Analyzing these models, we show that the optimal allocation balances expected marginal profits across the disposition alternatives. A detailed numerical study reveals that a revenue management approach to the disposition problem significantly outperforms the current practice of focusing exclusively on high-margin options, and we identify conditions under which this improvement is the highest. We also show that the value recovered from the returned products critically depends on the coordination between forward and reverse supply chain decisions.remanufacturing;revenue management;onderdelen;revenues;spare parts inventory
Applying Revenue Management to the Reverse Supply Chain
We study the disposition decision for product returns in a closed-loop supply chain. Motivated by the asset recovery process at IBM, we consider two disposition alternatives. Returns may be either refurbished for reselling or dismantled for spare parts. Reselling a refurbished unit typically yields higher unit margins. However, demand is uncertain. A common policy in many firms is to rank disposition alternatives by unit margins. We show that a revenue management approach to the disposition decision which explicitly incorporates demand uncertainty can increase profits significantly. We discuss analogies between the disposition problem and the classical airline revenue management problem. We then develop single period and multi-period stochastic optimization models for the disposition problem. Analyzing these models, we show that the optimal allocation balances expected marginal profits across the disposition alternatives. A detailed numerical study reveals that a revenue management approach to the disposition problem significantly outperforms the current practice of focusing exclusively on high-margin options, and we identify conditions under which this improvement is the highest. We also show that the value recovered from the returned products critically depends on the coordination between forward and reverse supply chain decisions
Incorporating oldman saltbush hay and prickly pear in diets for red Sindhi calves
This study was designed to evaluate the nutrient intake, digestibility, degradability, and ruminal characteristics of Sindhi heifers fed diets that contained a combined total of 75% oldman saltbush hay (hereafter saltbush hay) and prickly pear cactus. Eight 12-month old intact male red Sindhi calves (four fistulated and four non-fistulated) with an initial mean weight of 170 ± 5 kg were assigned to 4 à 4 Latin squares, where factors consisted of four diets, namely 15% hay and 60% cactus; 30% hay and 45% cactus; 45% hay and 30% cactus; and 60% hay and 15% cactus, and four times at which rumen fluid was collected. Neutral detergent fibre (NDF) and acid detergent fibre (ADF) intakes in kg/day and NDF in percentage live weight (LW), water intake, salinity, and conductivity increased with hay level. Intake and digestibility of non-fibrous carbohydrates were curvilinear with higher values in diets containing 30% saltbush hay. The apparent digestibility of dry matter (DM) and organic matter decreased linearly as the concentration of saltbush hay increased in the diet. The pH of the rumen fluid was within the acceptable range for favourable microbial growth. The low temperature and high salinity and conductivity indices in the diets should be viewed with caution at higher concentrations of saltbush hay, because of a possible decrease in nutrient absorption and the development of health problems in the animals. Apparent degradability coefficients of DM and NDF were affected significantly by inclusion of prickly pear and saltbush hay in the diets.Keywords: animal nutrition, apparent digestibility, Atriplex nummularia Lindl, Opuntia ficus, ruminal degradation, semi-arid environmen
Skeletal muscle transcriptional coactivator PGC-1alpha mediates mitochondrial, but not metabolic, changes during calorie restriction
Calorie restriction (CR) is a dietary intervention that extends lifespan and healthspan in a variety of organisms. CR improves mitochondrial energy production, fuel oxidation, and reactive oxygen species (ROS) scavenging in skeletal muscle and other tissues, and these processes are thought to be critical to the benefits of CR. PGC-1alpha is a transcriptional coactivator that regulates mitochondrial function and is induced by CR. Consequently, many of the mitochondrial and metabolic benefits of CR are attributed to increased PGC-1alpha activity. To test this model, we examined the metabolic and mitochondrial response to CR in mice lacking skeletal muscle PGC-1alpha (MKO). Surprisingly, MKO mice demonstrated a normal improvement in glucose homeostasis in response to CR, indicating that skeletal muscle PGC-1alpha is dispensable for the whole-body benefits of CR. In contrast, gene expression profiling and electron microscopy (EM) demonstrated that PGC-1alpha is required for the full CR-induced increases in mitochondrial gene expression and mitochondrial density in skeletal muscle. These results demonstrate that PGC-1alpha is a major regulator of the mitochondrial response to CR in skeletal muscle, but surprisingly show that neither PGC-1alpha nor mitochondrial biogenesis in skeletal muscle are required for the whole-body metabolic benefits of CR
Calibration of Plastic Phoswich Detectors for Charged Particle Detection
The response of an array of plastic phoswich detectors to ions of has been measured from =12 to 72 MeV. The detector response has been
parameterized by a three parameter fit which includes both quenching and high
energy delta-ray effects. The fits have a mean variation of with
respect to the data.Comment: 17 pages, 5 figure
2008-2009 President\u27s Report
The Linfield College President\u27s Annual Report is a collection of information about the year in review, including academics, student life and athletics, enrollment, finances, philanthropy, and leadership
On noise treatment in radio measurements of cosmic ray air showers
Precise measurements of the radio emission by cosmic ray air showers require
an adequate treatment of noise. Unlike to usual experiments in particle
physics, where noise always adds to the signal, radio noise can in principle
decrease or increase the signal if it interferes by chance destructively or
constructively. Consequently, noise cannot simply be subtracted from the
signal, and its influence on amplitude and time measurement of radio pulses
must be studied with care. First, noise has to be determined consistently with
the definition of the radio signal which typically is the maximum field
strength of the radio pulse. Second, the average impact of noise on radio pulse
measurements at individual antennas is studied for LOPES. It is shown that a
correct treatment of noise is especially important at low signal-to-noise
ratios: noise can be the dominant source of uncertainty for pulse height and
time measurements, and it can systematically flatten the slope of lateral
distributions. The presented method can also be transfered to other experiments
in radio and acoustic detection of cosmic rays and neutrinos.Comment: 4 pages, 6 figures, submitted to NIM A, Proceedings of ARENA 2010,
Nantes, Franc
The LOPES experiment - recent results, status and perspectives
The LOPES experiment at the Karlsruhe Institute of Technology has been taking
radio data in the frequency range from 40 to 80 MHz in coincidence with the
KASCADE-Grande air shower detector since 2003. Various experimental
configurations have been employed to study aspects such as the energy scaling,
geomagnetic dependence, lateral distribution, and polarization of the radio
emission from cosmic rays. The high quality per-event air shower information
provided by KASCADE-Grande has been the key to many of these studies and has
even allowed us to perform detailed per-event comparisons with simulations of
the radio emission. In this article, we give an overview of results obtained by
LOPES, and present the status and perspectives of the ever-evolving experiment.Comment: Proceedings of the ARENA2010 conference, Nantes, Franc
Investigation of the Properties of Galactic Cosmic Rays with the KASCADE-Grande Experiment
The properties of galactic cosmic rays are investigated with the
KASCADE-Grande experiment in the energy range between and
eV. Recent results are discussed. They concern mainly the all-particle energy
spectrum and the elemental composition of cosmic rays.Comment: Proc. RICAP 09, Nucl. Instr. and Meth. in pres
The spectrum of high-energy cosmic rays measured with KASCADE-Grande
The energy spectrum of cosmic rays between 10**16 eV and 10**18 eV, derived
from measurements of the shower size (total number of charged particles) and
the total muon number of extensive air showers by the KASCADE-Grande
experiment, is described. The resulting all-particle energy spectrum exhibits
strong hints for a hardening of the spectrum at approximately 2x10**16 eV and a
significant steepening at c. 8x10**16 eV. These observations challenge the view
that the spectrum is a single power law between knee and ankle. Possible
scenarios generating such features are discussed in terms of astrophysical
processes that may explain the transition region from galactic to extragalactic
origin of cosmic rays.Comment: accepted by Astroparticle Physics June 201
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