223 research outputs found
Patients' inability to perform a preoperative cardiopulmonary exercise test or demonstrate an anaerobic threshold is associated with inferior outcomes after major colorectal surgery.
BACKGROUND: Surgical patients with poor functional capacity, determined by oxygen consumption at anaerobic threshold (AT) during cardiopulmonary exercise testing (CPET), experience longer hospital stays and worse short- and medium-term survival. However, previous studies excluded patients who were unable to perform a CPET or who failed to demonstrate an AT. We hypothesized that such patients are at risk of inferior outcomes after elective surgery. METHODS: All patients undergoing major colorectal surgery attempted CPET to assist in the planning of care. Patients were stratified by their test results into Fit (AT ≥ 11.0 ml O2 kg(-1) min(-1)), Unfit (AT < 11.0 ml O2 kg(-1) min(-1)), or Unable to CPET groups (failed to pedal or demonstrate an AT). For each group, we determined hospital stay and mortality. RESULTS: Between March 2009 and April 2010, 269 consecutive patients were screened, and proceeded to bowel resection. Median hospital stay was 8 days (IQR 5.1-13.4) and there were 44 deaths (16%) at 2 yr; 26 (9.7%) patients were categorized as Unable to CPET, 69 (25.7%) Unfit and 174 (64.7%) Fit. There were statistically significant differences between the three groups in hospital stay [median (IQR) 14.0 (10.5-23.8) vs 9.9 (5.5-15) vs 7.1 (4.9-10.8) days, P < 0.01] and mortality at 2 yr [11/26 (42%) vs 14/69 (20%) vs 19/174 (11%), respectively (P < 0.01)] although the differences between Unable and Unfit were not statistically different. CONCLUSIONS: Patients' inability to perform CPET is associated with inferior outcomes after major colorectal surgery. Future studies evaluating CPET in risk assessment for major surgery should report outcomes for this subgroup
Approximate Analytical Solutions to the Initial Data Problem of Black Hole Binary Systems
We present approximate analytical solutions to the Hamiltonian and momentum
constraint equations, corresponding to systems composed of two black holes with
arbitrary linear and angular momentum. The analytical nature of these initial
data solutions makes them easier to implement in numerical evolutions than the
traditional numerical approach of solving the elliptic equations derived from
the Einstein constraints. Although in general the problem of setting up initial
conditions for black hole binary simulations is complicated by the presence of
singularities, we show that the methods presented in this work provide initial
data with and norms of violation of the constraint equations
falling below those of the truncation error (residual error due to
discretization) present in finite difference codes for the range of grid
resolutions currently used. Thus, these data sets are suitable for use in
evolution codes. Detailed results are presented for the case of a head-on
collision of two equal-mass M black holes with specific angular momentum 0.5M
at an initial separation of 10M. A straightforward superposition method yields
data adequate for resolutions of , and an "attenuated" superposition
yields data usable to resolutions at least as fine as . In addition, the
attenuated approximate data may be more tractable in a full (computational)
exact solution to the initial value problem.Comment: 6 pages, 5 postscript figures. Minor changes and some points
clarified. Accepted for publication in Phys. Rev.
Introduction to Isolated Horizons in Numerical Relativity
We present a coordinate-independent method for extracting mass (M) and
angular momentum (J) of a black hole in numerical simulations. This method,
based on the isolated horizon framework, is applicable both at late times when
the black hole has reached equilibrium, and at early times when the black holes
are widely separated. We show how J and M can be determined in numerical
simulations in terms of only those quantities which are intrinsic to the
apparent horizon. We also present a numerical method for finding the rotational
symmetry vector field (required to calculate J) on the horizon.Comment: 14 pages, revtex4, 7 figures. Final PRD versio
Tracking Black Holes in Numerical Relativity
This work addresses and solves the problem of generically tracking black hole
event horizons in computational simulation of black hole interactions.
Solutions of the hyperbolic eikonal equation, solved on a curved spacetime
manifold containing black hole sources, are employed in development of a robust
tracking method capable of continuously monitoring arbitrary changes of
topology in the event horizon, as well as arbitrary numbers of gravitational
sources. The method makes use of continuous families of level set viscosity
solutions of the eikonal equation with identification of the black hole event
horizon obtained by the signature feature of discontinuity formation in the
eikonal's solution. The method is employed in the analysis of the event horizon
for the asymmetric merger in a binary black hole system. In this first such
three dimensional analysis, we establish both qualitative and quantitative
physics for the asymmetric collision; including: 1. Bounds on the topology of
the throat connecting the holes following merger, 2. Time of merger, and 3.
Continuous accounting for the surface of section areas of the black hole
sources.Comment: 14 pages, 16 figure
Search for the decay in the momentum region
We have searched for the decay in the kinematic
region with pion momentum below the peak. One event was
observed, consistent with the background estimate of . This
implies an upper limit on
(90% C.L.), consistent with the recently measured branching ratio of
, obtained using the standard model
spectrum and the kinematic region above the peak. The
same data were used to search for , where is a weakly
interacting neutral particle or system of particles with .Comment: 4 pages, 2 figure
First Observation of Coherent Production in Neutrino Nucleus Interactions with 2 GeV
The MiniBooNE experiment at Fermilab has amassed the largest sample to date
of s produced in neutral current (NC) neutrino-nucleus interactions at
low energy. This paper reports a measurement of the momentum distribution of
s produced in mineral oil (CH) and the first observation of coherent
production below 2 GeV. In the forward direction, the yield of events
observed above the expectation for resonant production is attributed primarily
to coherent production off carbon, but may also include a small contribution
from diffractive production on hydrogen. Integrated over the MiniBooNE neutrino
flux, the sum of the NC coherent and diffractive modes is found to be (19.5
1.1 (stat) 2.5 (sys))% of all exclusive NC production at
MiniBooNE. These measurements are of immediate utility because they quantify an
important background to MiniBooNE's search for
oscillations.Comment: Submitted to Phys. Lett.
Analysis of LIGO data for gravitational waves from binary neutron stars
We report on a search for gravitational waves from coalescing compact binary
systems in the Milky Way and the Magellanic Clouds. The analysis uses data
taken by two of the three LIGO interferometers during the first LIGO science
run and illustrates a method of setting upper limits on inspiral event rates
using interferometer data. The analysis pipeline is described with particular
attention to data selection and coincidence between the two interferometers. We
establish an observational upper limit of 1.7 \times 10^{2}M_\odot$.Comment: 17 pages, 9 figure
Further search for the decay in the momentum region P < 195 MeV/c
We report the results of a search for the decay
in the kinematic region with momentum MeV/c using the
data collected by the E787 experiment at BNL. No events were observed. When
combined with our previous search in this region, one candidate event with an
expected background of events results in a 90% C.L. upper limit
of on the branching ratio of .
We also report improved limits on the rates of and where are hypothetical, massless, long-lived
neutral particles.Comment: 5 pages, 3 figures, Accepted for publication in Phys. Rev.
Test of Lorentz and CPT violation with Short Baseline Neutrino Oscillation Excesses
The sidereal time dependence of MiniBooNE electron neutrino and anti-electron
neutrino appearance data are analyzed to search for evidence of Lorentz and CPT
violation. An unbinned Kolmogorov-Smirnov test shows both the electron neutrino
and anti-electron neutrino appearance data are compatible with the null
sidereal variation hypothesis to more than 5%. Using an unbinned likelihood fit
with a Lorentz-violating oscillation model derived from the Standard Model
Extension (SME) to describe any excess events over background, we find that the
electron neutrino appearance data prefer a sidereal time-independent solution,
and the anti-electron neutrino appearance data slightly prefer a sidereal
time-dependent solution. Limits of order 10E-20 GeV are placed on combinations
of SME coefficients. These limits give the best limits on certain SME
coefficients for muon neutrino to electron neutrino and anti-muon neutrino to
anti-electron neutrino oscillations. The fit values and limits of combinations
of SME coefficients are provided.Comment: 14 pages, 3 figures, and 2 tables, submitted to Physics Letters
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