De Venecia a Famagusta (Viaje de ’Eliyahu da Pesaro - 1563)

This paper offers the very accurate and interesting description of a journey through the Mediterranean, from Venice to Famagusta, of an italian Jew, Eliyahu da Pesaro, in 1563, based on the hebrew text of the unique ms. extant at the Bibliothèque Nationale de Paris. The four main topics of the text are: 1) the ambiance and general situation of the Venetian port during the previous days of the departure of the galleon. 2) the conditions of the voyage on the boat itself 3) the Eliyahu's itinerary trhough the Adriatic and Egean seas and 4) the island of Cyprus, specially the city of Eamagusta and the living conditions there.El texto que aquí ofrecemos es la primera traducción completa -y anotada- a una lengua occidental de un único manuscrito hebreo (n. 274 en cuarto, ancien fond n. 124, folios 112-123 v. de la Bibliothèque Nationale de Paris) conteniendo la relación del viaje por el Mediterráneo, desde Venecia a Famagusta, del judío italiano Eliyahu da Pesaro en 1563. El contenido puede dividirse en cuatro grandes apartados del mayor interés: 1) Las recomendaciones, avisos y sugerencias del viajero en todo lo referente a los trámites y gestiones previas a la contratación de pasaje y embarque en las galeras, así como el ambiente y agitación reinates en Venecia en los días anteriores a la partida. 2) Una minuciosa y muy detallada descripción de la galera. 3) La singladura por el Adriático y Egeo, hasta Famagusta y 4) Descripción de la isla de Chipre, de sus habitantes -tanto los cristianos ortodoxos como los judíos- y sus usos y costumbres

El problema de las «entregas»: Prestamistas judíos en el Norte de Castilla (Belorado y Miranda de Ebro hacia 1300)

Focusing especially on Jewish moneylending, the article explores economic relations between Jews and Christians in Northern Castile at the turn of the fourteenth century. During interfaith economic transactions, Jews and Christians followed the procedures established by customary law, and engaged in negotiations to resolve conflicts and generate inter-communal consensus. As more and more Christians defaulted on their loans, however, such negotiations often collapsed due to a combination of internal and external pressures. In Belorado and Miranda de Ebro, royal assistance with debt collections elicited strong protests from town officials, who accused Jewish moneylenders of violating local privileges and impoverishing Christian debtors. Tensions developed between Jewish and Christian residents of these towns when the traditional mechanisms of conflict resolution were upended, and the enforcement of loan repayment was taken away from local control.Estudio de las relaciones económicas entre judíos y cristianos a comienzos del siglo xiv en el Norte de Castilla, especialmente en relación al préstamo de dinero efectuado por judíos. Tratándose de transacciones económicas entre individuos de distinta confesión religiosa, los interesados recurrían a los procedimientos establecidos en el derecho consuetudinario, y hacían uso de la negociación con el objetivo de resolver conflictos y generar el mayor consenso posible entre las distintas comunidades. A medida que los prestatarios cristianos iban incumpliendo la devolución de préstamos, tales negociaciones fracasaron debido a una combinación de factores internos y externos. En Belorado y en Miranda de Ebro, la colaboración de los oficiales reales en la colección de las deudas suscitó protestas de los concejos, que acusaban a los prestadores judíos de violar los privilegios locales y de empobrecer a los deudores. Las tensiones entre los cristianos y los judíos de estas villas fueron en aumento cuando los mecanismos de resolución de conflictos quedaron trastocados y la ejecución de los pagos de las deudas quedó sustraída al control local

Why Property Matters? New Varieties of Domestic Patriarchy in Turkey

This article extends theories on varieties of gender regimes by arguing for the significance of property. Drawing on the case study of Turkey, it proposes that gendered property ownership diversifies patriarchal relations of labor. This historical-sociology-based case study method is used to differentiate two forms of domestic patriarchy: premodern and modern. In premodern domestic patriarchy, women’s exclusion from agricultural landownership, in conjunction with the dominance of small landownership, sustains the patriarchal exploitation of labor in agriculture. In modern domestic patriarchy, women’s exclusion from paid employment, along with dispossession and increasing wage dependency, maintains the patriarchal exploitation of labor within the home

Complete Loss of Netrin-1 Results in Embryonic Lethality and Severe Axon Guidance Defects without Increased Neural Cell Death

Netrin-1 regulates cell migration and adhesion during the development of the nervous system, vasculature, lung, pancreas, muscle, and mammary gland. It is also proposed to function as a dependence ligand that inhibits apoptosis; however, studies disagree regarding whether netrin-1 loss-of-function mice exhibit increased cell death. Furthermore, previously studied netrin-1 loss-of-function gene-trap mice express a netrin-1-β-galactosidase protein chimera with potential for toxic gain-of-function effects, as well as a small amount of wild-type netrin-1 protein. To unambiguously assess loss of function, we generated netrin-1 floxed and netrin-1 null mouse lines. Netrin-1−/− mice die earlier and exhibit more severe axon guidance defects than netrin-1 gene-trap mice, revealing that complete loss of function is more severe than previously reported. Netrin-1−/− embryos also exhibit increased expression of the netrin receptors DCC and neogenin that are proposed dependence receptors; however, increased apoptosis was not detected, inconsistent with netrin-1 being an essential dependence receptor ligand in the embryonic spinal cord

Trophic factors differentiate dopamine neurons vulnerable to Parkinson's disease

Recent studies suggest a variety of factors characterize substantia nigra neurons vulnerable to Parkinson's disease, including the transcription factors pituitary homeobox 3 (Pitx3) and orthodenticle homeobox 2 (Otx2) and the trophic factor receptor deleted in colorectal cancer (DCC), but there is limited information on their expression and localization in adult humans. Pitx3, Otx2, and DCC were immunohistochemically localized in the upper brainstem of adult humans and mice and protein expression assessed using relative intensity measures and online microarray data. Pitx3 was present and highly expressed in most dopamine neurons. Surprisingly, in our elderly subjects no Otx2 immunoreactivity was detected in dopamine neurons, although Otx2 gene expression was found in younger cases. Enhanced DCC gene expression occurred in the substantia nigra, and higher amounts of DCC protein characterized vulnerable ventral nigral dopamine neurons. Our data show that, at the age when Parkinson's disease typically occurs, there are no significant differences in the expression of transcription factors in brainstem dopamine neurons, but those most vulnerable to Parkinson's disease rely more on the trophic factor receptor DCC than other brainstem dopamine neurons

Diet and food strategies in a southern al-Andalusian urban environment during Caliphal period, ecija, Sevilla

The Iberian medieval period is unique in European history due to the widespread socio-cultural changes that took place after the arrival of Arabs, Berbers and Islam in 711 AD. Recently, isotopic research has been insightful on dietary shifts, status, resource availability and the impact of environment. However, there is no published isotopic research exploring these factors in southern Iberian populations, and as the history of this area differs to the northern regions, this leaves a significant lacuna in our knowledge. This research fills this gap via isotopic analysis of human (n = 66) and faunal (n = 13) samples from the 9th to the 13th century Écija, a town renowned for high temperatures and salinity. Stable carbon (δ13C) and nitrogen (δ15N) isotopes were assessed from rib collagen, while carbon (δ13C) values were derived from enamel apatite. Human diet is consistent with C3 plant consumption with a very minor contribution of C4 plants, an interesting feature considering the suitability of Écija to C4 cereal production. δ15N values vary among adults, which may suggest variable animal protein consumption or isotopic variation within animal species due to differences in foddering. Consideration of δ13C collagen and apatite values together may indicate sugarcane consumption, while moderate δ15N values do not suggest a strong aridity or salinity effect. Comparison with other Iberian groups shows similarities relating to time and location rather than by religion, although more multi-isotopic studies combined with zooarchaeology and botany may reveal subtle differences unobservable in carbon and nitrogen collagen studies alone.OLC is funded by Plan Galego I2C mod.B (ED481D 2017/014). The research was partially funded by the projects “Galician Paleodiet” and by Consiliencia network (ED 431D2017/08) Xunta de GaliciaS