Preguntas a Hilda Sabato

The essay analyzes Hilda Sabato’s last book (Repúblicas del Nuevo Mundo. El experimento político latinoamericano del siglo XIX, Buenos Aires: Taurus/Penguin Random House, 2021) and poses two main questions. The first one points to the reasons why Spanish American independences have not been part of the narratives about the Atlantic democratic revolutions. Is this situation a consequence of the hegemonic trends in international historiographical production? The second refers to Hilda Sabato’s own experience in the formation of networks, circulations, and practices of the discipline leading to the theoretical and methodological renewal of political history, which has recently placed those independences as important topics within the broad  history of political modernity.El ensayo analiza el último libro de Hilda Sabato y plantea dos grandes interrogantes. El primero apunta a desentrañar el motivo por el cual las independencias hispanoamericanas no han formado parte de la gran narrativa sobre las revoluciones democráticas del Atlántico Norte. ¿Esta situación se vincula con las hegemonías de la producción historiográfica internacional? El segundo se refiere a su propia experiencia en la formación de redes, circulaciones y prácticas de la disciplina histórica en la renovación teórica y metodológica de la historia política, que permitió incluir las Independencias como parte del amplio fenómeno de la política moderna

Catecismo de oratoria sagrada. Obra póstuma del Rmo. P. Gregorio Domínguez, preposito general del órden de clerigos menores y predicador de S.M.

Copia digital : Diputación de Málaga. Biblioteca Canovas del Castillo, 201

Pluralism of property rights and privatization of common lands in the early modern and modern periods: Latin america and Spain in a comparative perspective

El dossier que presentamos se propone analizar diferentes aspectos de la problemática de los derechos de propiedad en las sociedades agrarias prestando especial atención a la propiedad comunal o indivisa. Esta temática es de vital importancia para los estudiosos de la historia rural, pero también para los investigadores y público en general interesado en conocer las estructuras socioeconómicas e institucionales de las diferentes regiones peninsulares e iberoamericanas.Facultad de Humanidades y Ciencias de la Educació

Enhancing Night and Day Circadian Contrast through Sleep Education in Prediabetes and Type 2 Diabetes Mellitus: A Randomized Controlled Trial

Background: Evidence supports a causal relationship between circadian disturbance and impaired glucose homeostasis. Methods: To determine the effect of an educational intervention delivered by primary care nurses to improve sleep hygiene, a parallel, open-label clinical trial in subjects aged 18 and older with impaired fasting glucose (IFG) or type 2 diabetes mellitus (T2DM) was performed. Study variables were sex, age, fasting glucose, glycated haemoglobin A1c (HbA1c), Pittsburgh Sleep Quality Index (PSQI), sleep duration and efficiency, body mass index, antidiabetic treatment, diet and physical exercise. An individual informative educational intervention was carried out following a bidirectional feedback method. The intervention aimed to develop skills to improve sleep through nine simple tips. An analysis of covariance was performed on all the mean centred outcome variables controlling for the respective baseline scores. Results: In the intervention group, PSQI dropped, the duration and quality of sleep increased, and a decrease in fasting glucose and in HbA1c levels was observed. Conclusion: The proposed intervention is effective for improving sleep quality, length and efficiency, and for decreasing fasting glucose and HbA1c levels in only 3 months. These findings support the importance of sleep and circadian rhythm education focused on improving IFG and T2DM

Expresión Gráfica Arquitectónica en un proyecto de comunicación total: Taller Síntesis

Junta de Andalucía-Consejería de Política TerritorialEscuela Técnica Superior de Arquitectura de la Universidad de SevillaExcmo. Ayuntamiento de SevillaColegio Oficial de Arquitectos de Andalucía Occidenta

Differential profile of ultrasound findings associated with malignancy in mixed and solid thyroid nodules in an elderly female population

Objective. Ultrasonographic characteristics are associated with thyroid malignancy. Our aim was to compare the diagnostic value of ultrasound features in the detection of thyroid malignancy in both solid and mixed nodules. Methods. We prospectively studied female patients (≥50 years) referred to ultrasound-guided fine needle aspiration biopsy. Ultrasound features considered suspicious were hypoechogenicity, microcalcifications, irregular margins, high anteroposterior (AP)/axial-ratio, and absent halo. Associations were separately assessed in mixed and solid nodules. Results. In a group of 504 elderly female patients (age =  years), the frequency of malignant cytology was 6%. Thirty-one percent of nodules were mixed and 60% were solid. The rate of malignant cytology was similar for mixed and solid nodules (7.4 versus 5.8%, : 0.56). While in mixed nodules none of the ultrasound characteristics were associated with malignant cytology, in solid nodules irregular margins and microcalcifications were significant (all ). The combination of irregular margins and/or microcalcifications significantly increased the association with malignant cytology only in solid nodules (OR: 2.76 (95% CI: 1.25–6.10), : 0.012). Conclusions. Ultrasound features were of poor diagnostic value in mixed nodules, which harbored malignant lesions as often as solid nodules. Our findings challenge the recommended minimal size for ultrasound-guided fine needle aspiration biopsy in mixed nodules.Fil: Vera, María Inés. Dr. Cesar Milstein Hospital; ArgentinaFil: Meroño, Tomás. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Urrutia, María Agustina. Dr. Cesar Milstein Hospital; ArgentinaFil: Parisi, Carina. Dr. Cesar Milstein Hospital; ArgentinaFil: Morosan, Yanina. Dr. Cesar Milstein Hospital; ArgentinaFil: Rosmarin, Melanie. Dr. Cesar Milstein Hospital; ArgentinaFil: Schnitman, Marta. Dr. Cesar Milstein Hospital; ArgentinaFil: Brites, Fernando Daniel. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Grisendi, Silvio. Dr. Cesar Milstein Hospital; ArgentinaFil: Serrano, María Sol. Dr. Cesar Milstein Hospital; ArgentinaFil: Luciani, Wilfredo. Dr. Cesar Milstein Hospital; ArgentinaFil: Serrano, Leonardo. Dr. Cesar Milstein Hospital; ArgentinaFil: Zuk, Carlos. Dr. Cesar Milstein Hospital; ArgentinaFil: de Barrio, Guillermo. Dr. Cesar Milstein Hospital; ArgentinaFil: Cejas, Claudia. Dr. Cesar Milstein Hospital; ArgentinaFil: Faingold, María Cristina. Dr. Cesar Milstein Hospital; ArgentinaFil: Brenta, Gabriela. Dr. Cesar Milstein Hospital; Argentin

Multivariate word properties in fluency tasks reveal markers of Alzheimer’s dementia

Version of Record online: 12 October 2023INTRODUCTION Verbal fluency tasks are common in Alzheimer's disease (AD) assessments. Yet, standard valid response counts fail to reveal disease-specific semantic memory patterns. Here, we leveraged automated word-property analysis to capture neurocognitive markers of AD vis-à-vis behavioral variant frontotemporal dementia (bvFTD). METHODS Patients and healthy controls completed two fluency tasks. We counted valid responses and computed each word's frequency, granularity, neighborhood, length, familiarity, and imageability. These features were used for group-level discrimination, patient-level identification, and correlations with executive and neural (magnetic resonanance imaging [MRI], functional MRI [fMRI], electroencephalography [EEG]) patterns. RESULTS Valid responses revealed deficits in both disorders. Conversely, frequency, granularity, and neighborhood yielded robust group- and subject-level discrimination only in AD, also predicting executive outcomes. Disease-specific cortical thickness patterns were predicted by frequency in both disorders. Default-mode and salience network hypoconnectivity, and EEG beta hypoconnectivity, were predicted by frequency and granularity only in AD. DISCUSSION Word-property analysis of fluency can boost AD characterization and diagnosis. Highlights We report novel word-property analyses of verbal fluency in AD and bvFTD. Standard valid response counts captured deficits and brain patterns in both groups. Specific word properties (e.g., frequency, granularity) were altered only in AD. Such properties predicted cognitive and neural (MRI, fMRI, EEG) patterns in AD. Word-property analysis of fluency can boost AD characterization and diagnosis.National Institutes of Health, National Institutes of Aging, Grant/Award Numbers: R01AG057234, R01AG075775; ANID: FONDECYT Regular, Grant/Award Numbers: 1210176, 1210195, 1220995; FONDAP, Grant/Award Number: 15150012; PIA/ANILLOS, Grant/Award Number: ACT210096; FONDEF, Grant/Award Number: ID20I10152; GBHI, Alzheimer’s Association, and Alzheimer’s Society: Alzheimer’s Association GBHI, Grant/Award Number: ALZ UK-22-865742; Alzheimer’s Association, Grant/Award Number: SG-20-725707; Latin American Brain Health Institute (BrainLat), Universidad Adolfo Ibáñez, Santiago, Chile, Grant/Award Number: #BL-SRGP2021-01; Programa Interdisciplinario de Investigación Experimental en Comunicación y Cognición (PIIECC), Facultad de Humanidades, USACH; Takeda, Grant/Award Number: CW2680521; Rainwater Charitable Foundation; Tau Consortium; European Commission: H2020-MSCA-IF-GFMULTI-LAND, Grant/Award Number: 10102581

The dilution peak, metallicity evolution, and dating of galaxy interactions and mergers

Strong inflows of gas from the outer disk to the inner kiloparsecs are induced during the interaction of disk galaxies. This inflow of relatively low-metallicity gas dilutes the metallicity of the circumnuclear gas. We have investigated several aspects of the process as the timing and duration of the dilution and its correlation with the induced star formation. We analysed major (1:1) gas-rich interactions and mergers, spanning a range of initial orbital characteristics. Star formation and metal enrichment from SNe are included in our model. Our results show that the strongest trend is between the star formation rate and the dilution of the metals in the nuclear region; i.e., the more intense the central burst of star formation, the more the gas is diluted. This trend comes from strong inflows of relatively metal-poor gas from the outer regions of both disks, which fuels the intense star formation and lowers the overall metallicity for a time. The strong inflows happen on timescales of about 10^8 years or less, and the most intense star formation and lowest gas phase metallicities are seen generally after the first pericentre passage. As the star formation proceeds and the merger advances, the dilution reduces and enrichment becomes dominant - ultimately increasing the metallicity of the circumnuclear gas to a level higher than the initial metallicities of the merging galaxies. The "fly-bys" - pairs that interact but do not merge - also cause some dilution. We even see some dilution early in the merger or in the "fly-bys" and thus do not observe a strong trend between the nuclear metallicities and separation in our simulations until the merger is well advanced. We also analyse the O and Fe enrichment of the ISM, and show that the evolution of the alpha/Fe ratios, as well as the dilution of the central gas metallicity, can be used as a clock for "dating" the interaction.Comment: 13 pages, 11 figures, A&A in press. Final version after language editin

Multimodal mechanisms of human socially reinforced learning across neurodegenerative diseases

Social feedback can selectively enhance learning in diverse domains. Relevant neurocognitive mechanisms have been studied mainly in healthy persons, yielding correlational findings. Neurodegenerative lesion models, coupled with multimodal brain measures, can complement standard approaches by revealing direct multidimensional correlates of the phenomenon. To this end, we assessed socially reinforced and non-socially reinforced learning in 40 healthy participants as well as persons with behavioural variant frontotemporal dementia (n = 21), Parkinson's disease (n = 31) and Alzheimer's disease (n = 20). These conditions are typified by predominant deficits in social cognition, feedback-based learning and associative learning, respectively, although all three domains may be partly compromised in the other conditions. We combined a validated behavioural task with ongoing EEG signatures of implicit learning (medial frontal negativity) and offline MRI measures (voxel-based morphometry). In healthy participants, learning was facilitated by social feedback relative to non-social feedback. In comparison with controls, this effect was specifically impaired in behavioural variant frontotemporal dementia and Parkinson's disease, while unspecific learning deficits (across social and non-social conditions) were observed in Alzheimer's disease. EEG results showed increased medial frontal negativity in healthy controls during social feedback and learning. Such a modulation was selectively disrupted in behavioural variant frontotemporal dementia. Neuroanatomical results revealed extended temporo-parietal and fronto-limbic correlates of socially reinforced learning, with specific temporo-parietal associations in behavioural variant frontotemporal dementia and predominantly fronto-limbic regions in Alzheimer's disease. In contrast, non-socially reinforced learning was consistently linked to medial temporal/hippocampal regions. No associations with cortical volume were found in Parkinson's disease. Results are consistent with core social deficits in behavioural variant frontotemporal dementia, subtle disruptions in ongoing feedback-mechanisms and social processes in Parkinson's disease and generalized learning alterations in Alzheimer's disease. This multimodal approach highlights the impact of different neurodegenerative profiles on learning and social feedback. Our findings inform a promising theoretical and clinical agenda in the fields of social learning, socially reinforced learning and neurodegeneration.Fil: Legaz, Agustina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; Argentina. Universidad Nacional de Córdoba; ArgentinaFil: Abrevaya, Sofia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; ArgentinaFil: Dottori, Martín. Universidad de San Andrés; ArgentinaFil: Campo, Cecilia González. Universidad de San Andrés; ArgentinaFil: Birba, Agustina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de San Andrés; ArgentinaFil: Martorell Caro, Miguel Angel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Neurociencia Cognitiva. Fundación Favaloro. Instituto de Neurociencia Cognitiva; ArgentinaFil: Aguirre, María Julieta. Universidad Nacional de Córdoba. Instituto de Investigaciones Psicológicas. - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones Psicológicas; ArgentinaFil: Slachevsky, Andrea. Universidad de Chile.; ChileFil: Aranguiz, Rafael. Instituto Nacional de Geriatría; ChileFil: Serrano, Cecilia Mariela. Unidad Asistencial "Dr. César Milstein"; ArgentinaFil: Gillan, Claire M.. University of California; Estados UnidosFil: Leroi, Iracema. University of California; Estados UnidosFil: García, Adolfo Martín. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de San Andrés; Argentina. University of California; Estados Unidos. Trinity College; Estados Unidos. Universidad Nacional de Cuyo; Argentina. Universidad de Santiago de Chile; ChileFil: Fittipaldi, Sol. Universidad de San Andrés; ArgentinaFil: Ibañez, Agustin Mariano. Universidad de San Andrés; Argentina. University of California; Estados Unidos. Trinity College; Estados Unidos. Universidad Adolfo Ibañez; Chile. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin