Optimized solid-state bipolar Marx modulador with resonant type droop compensation

Este trabalho foi financiado pelo Concurso Anual para Projetos de Investigação, Desenvolvimento, Inovação e Criação Artística (IDI&CA) 2016 do Instituto Politécnico de Lisboa. Código de referência IPL/2016/MBOCDTI_ISELIn this paper a voltage droop compensation based on a resonant circuit is proposed for the optimized solid-state bipolar Marx modulator. Keeping the modularity characteristics and the circuit topology, one auxiliary resonant stage was added to the existing Marx stages. The compensation concept consists of adding the auxiliary voltage to the output positive or negative pulse for voltage droop compensation. Simulation results are presented for five stages Marx circuit, 10% voltage droop, using 800 V per stage, 100 ps pulse duration at 50Hz frequency.info:eu-repo/semantics/publishedVersio

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A comprehensive model of predictors of quality of life in older adults with schizophrenia: results from the CSA study

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Late-onset and nonlate-onset schizophrenia: A comparison of clinical characteristics in a multicenter study

International audienceObjectives Data are scarce regarding the potential clinical differences between non-late onset schizophrenia (NLOS, i.e., disorder occurring before 40 years of age), late-onset schizophrenia (LOS, occurring between ages 40 and 60 years) and very-late-onset schizophrenia-like psychosis (VLOSLP, occurring after 60 years of age). Furthermore, previous research compared LOS patients with non-age matched NLOS patients. In this study, we sought to examine potential clinical differences between patients of similar age with LOS and NLOS. Methods/Design This is a cross-sectional multicentre study that recruited in- and outpatients older adults (aged >= 55 years) with an ICD-10 diagnosis of schizophrenia or schizoaffective disorder with NLOS and LOS. Sociodemographic and clinical characteristics, comorbidity, psychotropic medications, quality of life, functioning, and mental health care utilization were drawn for comparison. Results Two hundred seventy-two participants (79.8%) had NLOS, 61 (17.9%) LOS, and 8 (2.3%) VLOSLP. LOS was significantly and independently associated with greater severity of emotional withdrawal and lower severity of depression (all p < 0.05). However, the magnitude of these associations was modest, with significant adjusted odds ratios ranging from 0.71 to 1.24, and there were no significant between-group differences in other characteristics. Conclusion In an age-matched multicenter sample of elderly patients with schizophrenia, older adults with LOS were largely similar to older adults with NLOS in terms of clinical characteristics. The few differences observed may be at least partially related to symptom fluctuation with time. Implications of these findings for pharmacological and nonpharmacological management is yet to be determined

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Effects of depression and cognitive impairment on quality of life in older adults with schizophrenia spectrum disorder: Results from a multicenter study

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