The Iowa Homemaker vol.16, no.3

Cover by Dorothy Coe The Way to His Heart by Win Hanssen, page 2 “Don’ts” for the Rushee by Stella Mae Brinkman, page 3 Sally Says, “Swinging Shoulders – Swirling Skirts” by Katherine Hoffman, page 4 Travel With Richard Halliburton by Emma Jean Scudder, page 6 Have a Treasure-Hunt Spread by Louise Peterson, page 7 Vocational Possibilitites, page 8 Our 1936 Graduates at Work by Gay Starrak, page 9 Behind Bright Jackets, page 10 Is Your Room “You”? by Betty Shoemaker, page 11 What’s New in Home Economics, page 12 Do You Keep a Diary?, page 15 Books to Read, page 16 Catt Gown Is Historic, page 18 Dr. Nickell at Iowa State, page 18 Facts on Child Health, page 20 Want to Remember Names?, page 22 Vitamin A Deficiency Test, page 2

Travel With Richard Halliburton

"Boiled octopus-delicious though tough-is the daily fare of a group of Greek monks whom I have visited," related Richard Halliburton, world adventurer and writer, while on the Iowa State campus last spring.</p

The Iowa Homemaker vol.16, no.3

Cover by Dorothy Coe The Way to His Heart by Win Hanssen, page 2 “Don’ts” for the Rushee by Stella Mae Brinkman, page 3 Sally Says, “Swinging Shoulders – Swirling Skirts” by Katherine Hoffman, page 4 Travel With Richard Halliburton by Emma Jean Scudder, page 6 Have a Treasure-Hunt Spread by Louise Peterson, page 7 Vocational Possibilitites, page 8 Our 1936 Graduates at Work by Gay Starrak, page 9 Behind Bright Jackets, page 10 Is Your Room “You”? by Betty Shoemaker, page 11 What’s New in Home Economics, page 12 Do You Keep a Diary?, page 15 Books to Read, page 16 Catt Gown Is Historic, page 18 Dr. Nickell at Iowa State, page 18 Facts on Child Health, page 20 Want to Remember Names?, page 22 Vitamin A Deficiency Test, page 24</p

Identification of infants with increased type 1 diabetes genetic risk for enrollment into Primary Prevention Trials-GPPAD-02 study design and first results

Primary prevention of type 1 diabetes (T1D) requires intervention in genetically at-risk infants. The Global Platform for the Prevention of Autoimmune Diabetes (GPPAD) has established a screening program, GPPAD-02, that identifies infants with a genetic high risk of T1D, enrolls these into primary prevention trials, and follows the children for beta-cell autoantibodies and diabetes. Genetic testing is offered either at delivery, together with the regular newborn testing, or at a newborn health care visits before the age of 5 months in regions of Germany (Bavaria, Saxony, Lower Saxony), UK (Oxford), Poland (Warsaw), Belgium (Leuven), and Sweden (Region Skåne). Seven clinical centers will screen around 330 000 infants. Using a genetic score based on 46 T1D susceptibility single-nucleotide polymorphisms (SNPs) or three SNPS and a first-degree family history for T1D, infants with a high (>10%) genetic risk for developing multiple beta-cell autoantibodies by the age of 6 years are identified. Screening from October 2017 to December 2018 was performed in 50 669 infants. The prevalence of high genetic risk for T1D in these infants was 1.1%. Infants with high genetic risk for T1D are followed up and offered to participate in a randomized controlled trial aiming to prevent beta-cell autoimmunity and T1D by tolerance induction with oral insulin. The GPPAD-02 study provides a unique path to primary prevention of beta-cell autoimmunity in the general population. The eventual benefit to the community, if successful, will be a reduction in the number of children developing beta-cell autoimmunity and T1D.status: publishe