90 research outputs found

    Trends in life expectancy and lifespan variation by educational attainment: United States, 1990-2010

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    The educational gradient in life expectancy is well documented in the United States and in other low-mortality countries. Highly educated Americans, on average, live longer than their low-educated counterparts, who have recently seen declines in adult life expectancy. However, limiting the discussion on lifespan inequality to mean differences alone overlooks other dimensions of inequality and particularly disparities in lifespan variation. The latter represents a unique form of inequality, with higher variation translating into greater uncertainty in the time of death from an individual standpoint, and higher group heterogeneity from a population perspective. Using data from the National Vital Statistics System from 1990 to 2010, this is the first study to document trends in both life expectancy and S25—the standard deviation of age at death above 25—by educational attainment. Among low-educated whites, adult life expectancy declined by 3.1 years for women and by 0.6 years for men. At the same time, S25 increased by about 1.5 years among high school–educated whites of both genders, becoming an increasingly important component of total lifespan inequality. By contrast, college-educated whites benefited from rising life expectancy and record low variation in age at death, consistent with the shifting mortality scenario. Among blacks, adult life expectancy increased, and S25 plateaued or declined in nearly all educational attainment groups, although blacks generally lagged behind whites of the same gender on both measures. Documenting trends in lifespan variation can therefore improve our understanding of lifespan inequality and point to diverging trajectories in adult mortality across socioeconomic strata

    How having a college education can add a decade or more to your life expectancy

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    That there are gaps in the life expectancies between different groups is very well known – but what about the effect of education on how long people are expected to live? In new research, Isaac Sasson looks at the effects of having a college education on the life spans of different groups. He writes that white women with a college education can expect to live 9 years longer than those without a high-school degree, a difference that is nearly 12 years for white men, and almost 5 and nearly 9 for black women and men. He also finds that college-educated Americans have far less variation in their life spans compared to those with less education, who are more likely to die prematurely

    Age and COVID-19 mortality: A comparison of Gompertz doubling time across countries and causes of death

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    Background: Demographers have emphasized the importance of age in explaining the spread of COVID-19 and its impact on mortality. However, the relationship between COVID-19 mortality and age should be contextualized in relation to other causes of death. Objective: To compare the age pattern of COVID-19 mortality with other causes of death and across countries, and to use these regularities to impute age-specific death counts in countries with limited data. Methods: The COVID-19 mortality doubling time in a Gompertz context was compared with 65 major causes of death using US vital statistics. COVID-19 fatality doubling time was similarly compared across 27 countries and used for estimating death counts by age in Israel as a case in point. Results: First, COVID-19 mortality increases exponentially with age at a Gompertz rate near the median of aging-related causes of death, as well as pneumonia and influenza. Second, COVID-19 mortality levels are 2.8 to 8.2 times higher than pneumonia and influenza across the adult age range. Third, the relationship between both COVID-19 mortality and fatality and age varies considerably across countries. Conclusions: The increase in COVID-19 mortality with age resembles the population rate of aging. Country differences in the age pattern of COVID-19 mortality and fatality may point to differences in underlying population health, standards of clinical care, or data quality. Contribution: This study underscores the need to contextualize the age pattern of COVID-19 mortality in relation to other causes of death. Furthermore, it demonstrates how to estimate age-specific COVID-19 deaths in countries with limited data availability

    Group- and individual-based approaches to health inequality: towards an integration

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    When assessing health inequalities, should one compare health outcomes across predetermined groups (e.g., race, ethnicity, socioeconomic status), or across individuals? Group-based approaches comparing group-specific means do not account for intra-group heterogeneity. Yet, traditional approaches based on additive decompositions splitting total inequality in its within- and between-group components fail to elucidate the groups' relative performance. Here, we develop a third approach based on pairwise comparisons to evaluate not only the variability that might exist across individuals within and between groups, but also the relative performance of the different groups vis-a-vis each other¿thus integrating both perspectives into a coherent framework

    Mortality and kidnapping estimates for the Yazidi population in the area of Mount Sinjar, Iraq, in August 2014: a retrospective household survey

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    In August 2014, the so-called Islamic State of Iraq and Syria (ISIS) attacked the Yazidi religious minority living in the area of Mount Sinjar in Nineveh governorate, Iraq. We conducted a retrospective household survey to estimate the number and demographic profile of Yazidis killed and kidnapped

    Development and evaluation of an emulsion containing lycopene for combating acceleration of skin aging

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    Licopeno é um carotenóide com potente atividade antioxidante encontrado em grande quantidade no tomate e usado no combate a diversas doenças como doenças cardiovasculares e diferentes tipos de cânceres, incluindo o câncer de próstata. O objetivo desse trabalho foi desenvolver uma emulsão contendo extrato de licopeno obtido do tomate salada e avaliar a citotoxicidade do extrato, a estabilidade, o comportamento reológico, atividade antioxidante e permeação do fitocosmético. O cosmético foi desenvolvido utilizando fase oleosa contendo derivados de Karité e submetido à avaliação da estabilidade físico-química, espalhabilidade, análise térmica, comportamento reológico, qualidade microbiológica, citotoxicidade, atividade antioxidante e testes de permeação e retenção cutânea. Os resultados demonstraram que o fitocosmético é estável, apresenta comportamento reológico desejável para uma formulação tópica e é um produto promissor para ser utilizado no combate à aceleração do envelhecimento cutâneo.Lycopene, a carotenoid and potent antioxidant is found in large quantities in tomatoes. Lycopene combats diseases, such as cardiovascular disease and different types of cancer, including prostate cancer. However, its topical use in emulsion form for the combat of skin aging is under-explored. The aim of the present study was to develop an emulsion containing lycopene extracted from salad tomatoes and evaluate its cytotoxicity, stability, rheological behavior, antioxidant activity and phytocosmetic permeation. The developed cosmetic comprised an oil phase made up of shea derivatives and was evaluated in terms of its physiochemical stability, spreadability, thermal analysis, rheological behavior, microbiological quality, cytotoxicity, antioxidant activity, cutaneous permeation and retention. The results demonstrate that this phytocosmetic is stable, exhibits satisfactory rheological behavior for a topical formula and is a promising product for combating skin aging

    Aging and Autism Spectrum Disorder: Evidence from the Broad Autism Phenotype

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    This study investigated for the first time the Broad Autism Phenotype (BAP) in the context of older adulthood and its associations with real world executive function, social support, and both depression and anxiety symptomatology. Based on self-ratings of autistic traits, 66 older adults (60+ years old, range=61-88) were split into BAP (n=20) and control (n=46) groups. Individuals in the BAP group, even after controlling for age, education level, sex, and health problems, exhibited more real world executive function problems in multiple domains, reported lower levels of social support, and self-rated increased depression and anxiety symptomatology compared to the control group. Regression analysis revealed that level of social support was the strongest predictor of BAP traits across both groups, although real world executive function problems and depression symptomatology were also significant predictors. Moreover, when predicting anxiety and depression symptomatology, BAP traits were the strongest predictors above and beyond the effects of demographic factors, real world executive function problems, and social support levels. These findings suggest that the BAP in older adulthood imparts additional risks to areas of functioning that are known to be crucial to aging-related outcomes in the context of typical development. These results might in turn inform aging in autism spectrum disorder, which has been largely unexplored to date

    In Search of the jüdische Typus: A Proposed Benchmark to Test the Genetic Basis of Jewishness Challenges Notions of “Jewish Biomarkers”

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    The debate as to whether Jewishness is a biological trait inherent from an “authentic” “Jewish type” (jüdische Typus) ancestor or a system of beliefs has been raging for over two centuries. While the accumulated biological and anthropological evidence support the latter argument, recent genetic findings, bolstered by the direct-to-consumer genetic industry, purport to identify Jews or quantify one’s Jewishness from genomic data. To test the merit of claims that Jews and non-Jews are genetically distinguishable, we propose a benchmark where genomic data of Jews and non-Jews are hybridized over two generations and the observed and predicted Jewishness of the terminal offspring according to either the Orthodox religious law (Halacha) or the Israeli Law of Return are compared. Members of academia, the public, and 23andMe were invited to use the benchmark to test claims that Jews are genetically distinct from non-Jews. Here, we report the findings from these trials. We also compare the genomic similarity of ∼300 individuals from nearly thirty Afro-Eurasian Jewish communities to a simulated jüdische Typus population. The results are discussed in light of modern trends in the genetics of Jews and related fields and provide a tentative answer to the ageless question “who is a Jew?
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