PRÁTICAS PEDAGÓGICAS COM O USO DO LAPTOP: experiências a partir do projeto Um Computador por Aluno (UCA)

O presente artigo tem como objetivo mostrar as práticas pedagógicas desenvolvidas por professores com o uso do laptop em sala de aula, e conhecer como integram esta tecnologia ao cotidiano escolar. A pesquisa teve como sujeitos seis professoras dos anos iniciais do Ensino Fundamental de uma escola do Ceará. Como instrumentos de coleta, foram utilizados questionários, diário de campo, checklist e entrevistas. Como resultados, mostra-se a autonomia das professoras e as posturas das professoras frente às aulas com o laptop. A pesquisa mostra que, em determinadas situações, a tecnologia favorece a relação e proximidade entre professor e aluno, como também, o professor mostra uma construção quanto à sua autonomia e segurança nas atividades. Outro resultado é a credibilidade social dos professores em postar que, ao usar a tecnologia em sala de aula, podem ocasionar mudanças e influenciar na vida adulta dos alunos. Palavras-chave: Prática pedagógica. Formação de professores. Projeto um computador por aluno (UCA)

PRÁTICAS PEDAGÓGICAS COM O USO DO LAPTOP: experiências a partir do projeto Um Computador por Aluno (UCA)

O presente artigo tem como objetivo mostrar as práticas pedagógicas desenvolvidas por professores com o uso do laptop em sala de aula, e conhecer como integram esta tecnologia ao cotidiano escolar. A pesquisa teve como sujeitos seis professoras dos anos iniciais do Ensino Fundamental de uma escola do Ceará. Como instrumentos de coleta, foram utilizados questionários, diário de campo, checklist e entrevistas. Como resultados, mostra-se a autonomia das professoras e as posturas das professoras frente às aulas com o laptop. A pesquisa mostra que, em determinadas situações, a tecnologia favorece a relação e proximidade entre professor e aluno, como também, o professor mostra uma construção quanto à sua autonomia e segurança nas atividades. Outro resultado é a credibilidade social dos professores em postar que, ao usar a tecnologia em sala de aula, podem ocasionar mudanças e influenciar na vida adulta dos alunos. Palavras-chave: Prática pedagógica. Formação de professores. Projeto um computador por aluno (UCA)

Formação docente na era da cibercultura

O artigo discorre sobre como deve ser repensada a formação docente no contexto da cibercultura, termo estabelecido em torno da Internet, das redes sociais e mais recentemente das tecnologias móveis. Os argumentos levantados estão ancorados em resultados de uma pesquisa, realizada com três professores da rede pública de escolas do Ceará. Os dados baseiam-se no uso de ferramentas de comunicação (Facebook, Skype e WhatsApp) e dispositivos móveis durante um processo de formação de cunho colaborativo. Os resultados apontam para uma apropriação dessas ferramentas pelas professoras tanto na sua formação como no registro de suas práticas pedagógicas. Em conclusão, processos de aprendizagem que observamos na Cibercultura devem ser melhor compreendidos e incorporados à formação docent

Recurso Educacional Digital (RED) para os anos iniciais do Ensino Fundamental aspectos pedagógicos e a Base Nacional Comum Curricular

Este estudo teve como objetivo compreender os aspectos pedagógicos envolvidos no desenvolvimento de um Recurso Educacional Digital (RED) de Língua Portuguesa, fundamentado nas habilidades da Base Nacional Comum Curricular (BNCC). De natureza qualitativa, do tipo estudo de caso, a pesquisa parte do pressuposto de que é preciso aprofundar o desenvolvimento de RED a partir de aspectos de natureza pedagógica e não somente técnica. A pesquisa evidenciou elementos importantes do desenvolvimento pedagógico, como: Alinhamento teórico, Intencionalidade pedagógica e Consistência técnico-pedagógica. Esses aspectos devem ser considerados no desenvolvimento de RED, como parte primordial do desenvolvimento de recursos

MICROBIOLOGICAL QUALITY FROM PUPUNHA WASTE PROCESSING FRESH AND FLOUR PRODUCED IN DIFFERENT TREATMENTS

Os resíduos agroindustriais podem ser reaproveitados por meio da adição em alimentos industrializados. Entretanto, é necessário o estudo da segurança microbiológica dessa fonte de matéria-prima alternativa e sua inocuidade para o consumidor. Dessa forma, este trabalho teve como objetivo, avaliar a qualidade microbiológica, das bainhas residuais processamento do palmito, tanto in natura como nas farinhas produzidas em diferentes tratamentos. Foram avaliados o crescimento de populações de B. cereus, Coliformes a 45ºC e Salmonella sp, Os resíduos in natura e a farinha sanitizada seca à 60°C, apresentaram a maior contagem de B. cereus e desenvolvimento de coliformes 45°C. A farinha sanitizada seca à 80°C (FPS-80°C), obteve o melhor resultado microbiológico, representando o melhor tratamento para inibição do crescimento microbiológico na farinha, tornando este, um produto seguro para o consumo humano

East Asia Today

East Asia attracts growing interest in the West. Th e region is the world’s hotbed of economic growth, led by burgeoning China aided by more advanced Asian economies investing heavily in manufacturing and trading networks involving China. Western entrepreneurs clamor to join the China wave

Sustainable strategies based on glycine–betaine analogue ionic liquids for the recovery of monoclonal antibodies from cell culture supernatants

Monoclonal antibodies (mAbs) are of crucial interest for therapeutic purposes, particularly in vaccination and immunization, and in the treatment of life-threatening diseases. However, their downstream processing from the complex cell culture media in which they are produced still requires multiple steps, making mAbs extremely high-cost products. Therefore, the development of cost-effective, sustainable and biocompatible purification strategies for mAbs is in high demand to decrease the associated economic, environmental and health burdens. Herein, novel aqueous biphasic systems (ABS) composed of glycine–betaine analogue ionic liquids (AGB-ILs) and K2HPO4/KH2PO4 at pH 7.0, the respective three-phase partitioning (TPP) systems, and hybrid processes combined with ultrafiltration were investigated and compared in terms of performance as alternative strategies for the purification and recovery of anti-human interleukin-8 (anti-IL-8) mAbs, which are specific therapeutics in the treatment of inflammatory diseases, from Chinese Hamster Ovary (CHO) cell culture supernatants. With the studied ABS, mAbs preferentially partition to the IL-rich phase, with recovery yields up to 100% and purification factors up to 1.6. The best systems were optimized in what concerns the IL concentration, allowing to take advantage of IL-based three-phase partitioning approaches where a precipitate enriched in mAbs is obtained at the ABS interface, yielding 41.0% of IgG with a purification factor of 2.7 (purity of 60.9%). Hybrid processes combining the two previous techniques and an ultrafiltration step were finally applied, allowing the recovery of mAbs from the different fractions in an appropriate buffer solution for further biopharmaceutical formulations, while allowing the simultaneous IL removal and reuse. The best results were obtained with the hybrid process combining TPP and ultrafiltration, allowing to obtain mAbs with a purity higher than 60%. The recyclability of the IL was additionally demonstrated, revealing no losses in the purification and recovery performance of these systems for mAbs. The biological activity of anti-IL-8 mAbs is maintained after the several purification and recovery steps, indicating that the novel ABS, three-phase partitioning and hybrid processes comprising AGB-ILs are promising and sustainable strategies in mAbs downstream processing.publishe

Effectiveness of a cognitive behavioral intervention in patients with medically unexplained symptoms: cluster randomized trial

BACKGROUND: Medically unexplained symptoms are an important mental health problem in primary care and generate a high cost in health services.Cognitive behavioral therapy and psychodynamic therapy have proven effective in these patients. However, there are few studies on the effectiveness of psychosocial interventions by primary health care. The project aims to determine whether a cognitive-behavioral group intervention in patients with medically unexplained symptoms, is more effective than routine clinical practice to improve the quality of life measured by the SF-12 questionary at 12 month. METHODS/DESIGN: This study involves a community based cluster randomized trial in primary healthcare centres in Madrid (Spain). The number of patients required is 242 (121 in each arm), all between 18 and 65 of age with medically unexplained symptoms that had seeked medical attention in primary care at least 10 times during the previous year. The main outcome variable is the quality of life measured by the SF-12 questionnaire on Mental Healthcare. Secondary outcome variables include number of consultations, number of drug (prescriptions) and number of days of sick leave together with other prognosis and descriptive variables. Main effectiveness will be analyzed by comparing the percentage of patients that improve at least 4 points on the SF-12 questionnaire between intervention and control groups at 12 months. All statistical tests will be performed with intention to treat. Logistic regression with random effects will be used to adjust for prognostic factors. Confounding factors or factors that might alter the effect recorded will be taken into account in this analysis. DISCUSSION: This study aims to provide more insight to address medically unexplained symptoms, highly prevalent in primary care, from a quantitative methodology. It involves intervention group conducted by previously trained nursing staff to diminish the progression to the chronicity of the symptoms, improve quality of life, and reduce frequency of medical consultations. TRIAL REGISTRATION: The trial was registered with ClinicalTrials.gov, number NCT01484223 [http://ClinicalTrials.gov].S

Role of age and comorbidities in mortality of patients with infective endocarditis

[Purpose]: The aim of this study was to analyse the characteristics of patients with IE in three groups of age and to assess the ability of age and the Charlson Comorbidity Index (CCI) to predict mortality. [Methods]: Prospective cohort study of all patients with IE included in the GAMES Spanish database between 2008 and 2015.Patients were stratified into three age groups:<65 years,65 to 80 years,and ≥ 80 years.The area under the receiver-operating characteristic (AUROC) curve was calculated to quantify the diagnostic accuracy of the CCI to predict mortality risk. [Results]: A total of 3120 patients with IE (1327 < 65 years;1291 65-80 years;502 ≥ 80 years) were enrolled.Fever and heart failure were the most common presentations of IE, with no differences among age groups.Patients ≥80 years who underwent surgery were significantly lower compared with other age groups (14.3%,65 years; 20.5%,65-79 years; 31.3%,≥80 years). In-hospital mortality was lower in the <65-year group (20.3%,<65 years;30.1%,65-79 years;34.7%,≥80 years;p < 0.001) as well as 1-year mortality (3.2%, <65 years; 5.5%, 65-80 years;7.6%,≥80 years; p = 0.003).Independent predictors of mortality were age ≥ 80 years (hazard ratio [HR]:2.78;95% confidence interval [CI]:2.32–3.34), CCI ≥ 3 (HR:1.62; 95% CI:1.39–1.88),and non-performed surgery (HR:1.64;95% CI:11.16–1.58).When the three age groups were compared,the AUROC curve for CCI was significantly larger for patients aged <65 years(p < 0.001) for both in-hospital and 1-year mortality. [Conclusion]: There were no differences in the clinical presentation of IE between the groups. Age ≥ 80 years, high comorbidity (measured by CCI),and non-performance of surgery were independent predictors of mortality in patients with IE.CCI could help to identify those patients with IE and surgical indication who present a lower risk of in-hospital and 1-year mortality after surgery, especially in the <65-year group

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio