Enhancement Mechanical Properties of Some Cosmetics and Their Effect on Human Skin by Ultrasonic Technique

Some physical properties were  studied such as density, velocity, absorption coefficient, relaxation amplitude, compressibility, modulus of elasticity, and acoustic Impedance for four types of cosmetics available locally before  and after added polymer CMC for these cosmetics the results show that the addition of CMC polymer led to improve these properties, except compressibility decreased due to the addition of polymer, so we can deduce that the addition of polymer leads to improve the characteristics of cosmetics practically . Keywords: Carboxy methyl cellulose; Cosmetics; Mechanical properties; Ultrasound technique

Pedagogical Conditions of Formation Professional Competences of the Bachelor-Economist on the Basis of Understanding

The article describes the issues of professional training of bachelors of Economics in the modern University as a specific educational system. The work clarifies the specificity of professional activity of future bachelors of Economics as subjects of study. The article simulated the educational process as organized in the module-rating system of education in the modern University, developed a conceptual and technological models that determine our understanding of the nature of the content, technologies of formation of professionally significant competences of future bachelors of economy in the modern University. Besides, in the article the organizational-pedagogical conditions providing efficiency of realization of the model are formulated

Pedagogical Conditions of Formation Professional Competences of the Bachelor-Economist on the Basis of Understanding

The article describes the issues of professional training of bachelors of Economics in the modern University as a specific educational system. The work clarifies the specificity of professional activity of future bachelors of Economics as subjects of study. The article simulated the educational process as organized in the module-rating system of education in the modern University, developed a conceptual and technological models that determine our understanding of the nature of the content, technologies of formation of professionally significant competences of future bachelors of economy in the modern University. Besides, in the article the organizational-pedagogical conditions providing efficiency of realization of the model are formulated

Orally active antischistosomal early leads identified from the open access malaria box.

BACKGROUND: Worldwide hundreds of millions of schistosomiasis patients rely on treatment with a single drug, praziquantel. Therapeutic limitations and the threat of praziquantel resistance underline the need to discover and develop next generation drugs. METHODOLOGY: We studied the antischistosomal properties of the Medicines for Malaria Venture (MMV) malaria box containing 200 diverse drug-like and 200 probe-like compounds with confirmed in vitro activity against Plasmodium falciparum. Compounds were tested against schistosomula and adult Schistosoma mansoni in vitro. Based on in vitro performance, available pharmacokinetic profiles and toxicity data, selected compounds were investigated in vivo. PRINCIPAL FINDINGS: Promising antischistosomal activity (IC50: 1.4-9.5 µM) was observed for 34 compounds against schistosomula. Three compounds presented IC50 values between 0.8 and 1.3 µM against adult S. mansoni. Two promising early leads were identified, namely a N,N'-diarylurea and a 2,3-dianilinoquinoxaline. Treatment of S. mansoni infected mice with a single oral 400 mg/kg dose of these drugs resulted in significant worm burden reductions of 52.5% and 40.8%, respectively. CONCLUSIONS/SIGNIFICANCE: The two candidates identified by investigating the MMV malaria box are characterized by good pharmacokinetic profiles, low cytotoxic potential and easy chemistry and therefore offer an excellent starting point for antischistosomal drug discovery and development

Some inequalities for q-polygamma function and ζq-Riemann zeta functions

In this paper, we present some inequalities for q-polygamma functions and ζq-Riemann Zeta functions, using a q-analogue of Holder type inequality

Effect of Nitrohumic Acid Application on Some Morphological and Physiological Characteristics of Savory Plant (Satureja hortensis L.)

Introduction Savory is considered one of the most important medicinal plants, which is used in various food and medical industries. Nitrogen (N) plays a major role on the growth and yield of medicinal plants. Therefore, an adequate supply of N is required for successful production of savory. However, the application of chemical N fertilizers is associated with many obstacles such as groundwater ‎pollution, N enrichment of surface waters, and drop in the quality of plants. ‎Accordingly, nowadays, great attention has been paid to organic fertilizers. In this regard, humic acid-based fertilizers have shown promising results. Humic acids (HAs) could be converted into nitrohumic acids (NHAs) through the nitration process, in which nitro groups (NO2) are located on the aromatic rings. This process increases the N content of the HA. Thus, ‎‎NHAs can be used as organic N fertilizers in the cultivation of medicinal plants whose organic production is a priority. However, the ‎effects of these types of fertilizers on plant growth and physiological characteristics have not been well ‎understood. Accordingly, the present study for the first time investigates the effectiveness of NHA on the ‎morphological and physiological characteristics of savory, as well as N loss through leaching.‎ Materials and Methods In the current study, HA was initially extracted from leonardite (purchased from Yazd Golsang Kavir Company) as a rich source of HA. Then, NHA was prepared through the nitration process using nitric acid (50% by volume). After that, using FT-IR (Fourier transform infrared spectroscopy) and CHNS analysis the extracted HA and NHA were characterized, and their N content was determined. Afterward a ‎greenhouse experiment in a completely randomized design (CRD) with three replications was conducted ‎to determine the effects of 16 treatments, including control (without urea, HA and NHA), urea (U1, U2 and U3), humic acid ‎‎(HA1, HA2 and HA3), nitrohumic acid (NHA1, NHA2 and NHA3), urea-humic acid (U1HA1, U2HA2‎ and U3HA3), and urea-nitrohumic acid (U1NHA1, U2NHA2 and U3NHA3) on the morphological ‎and physiological characteristics of savory plant. The treatment levels were ‎determined as 40, 80, and 120 mg N kg-1 for the first, second and third level of the treatments, respectively. In the combined treatments of urea and HA or NHA, an equal fraction of the total nitrogen (N) was applied. At the end of the experiment, standard methods were used to assess various characteristics, including root length, leaf area, plant height, root volume, wet and dry weights of shoot and root, leaf chlorophyll index, concentrations of phosphorus, potassium, nitrogen, nitrate, and nitrate reductase in both the shoot and root. Additionally, leaching was conducted on specific days during the experiment, and the leachate was collected for nitrate measurement. Results and Discussion The results showed that using the nitration process, some characteristics of the NHA such as total acidity, the content of carboxylic and phenolic groups as well as N content improved as compared to the initial HA. Moreover, the results indicated that most of the morphological and physiological ‎traits of savory plants, including leaf area, plant height, root length, fresh and dry weights of root and shoot as well as chlorophyll index, and the concentration of nitrogen, phosphorous, potassium, nitrate and nitrate reductase enzyme were significantly higher in the NHA treatments than those of HA. In addition, the highest shoot dry weight was obtained in the combined treatments of U3NHA3 and U3HA3 as well as in the U3 treatment alone. The average rate of nitrate concentration increase in the U treatments was 1.77 times higher than the UNHA treatments. According to the results, U3 treatment indicated the highest nitrate loss which by using the U3NHA3 treatment, the mean concentration of nitrate ‎in the leachate decreased by about 40.5% as compared to the U3 treatment.‎ Conclusion The findings of this research revealed that most of the morphological and physiological ‎traits of savory plant showed better responses to the combined treatments of U3NHA3 and U3HA3 as well as to the U3 treatment alone. However, with regard to the lower accumulation of nitrate in the shoot of savory as well as to the lower nitrate leaching, the combined treatments were preferred. Accordingly, NHA can be ‎a alternative nitrogen source in increasing the yield and growth indicators of savory. However, the reasons behind the fact of the better performance of combined nitrogen treatments than the individual ones require more research in the future

Effect of dietary mannan oligosaccharide on growth performance, survival, body composition and intestinal microflora in great sturgeon juvenile (Huso huso Linnaeus, 1754)

The effect of dietary mannan oligosaccharide (MOS; active MOS®) on growth, survival, body composition and intestinal microflora in giant sturgeon juvenile (Huso huso) were investigated for 46 days. Basal diet were supplemented with 0 (control), 2 and 4 g/kg MOS in a totally randomized design trial in triplicate groups. The experiment was carried out in 900 L fiberglass tanks. Fifteen juveniles beluga with initially average weight of 46.89 ± 0.57 g were stocked and fed to satiation daily.Data was analysed by regression analysis and pearson correlation test. There were no significant differences in growth and feeding parameters between fish fed control and MOS supplementation diets (P>0.05), but group treated with 4 g/kg MOS showed significant differences in food intake (P0.05). Fish treated with 2 g/kg MOS showed significant differences in fat content of muscle tissue (P0.05) were recorded. No significant difference was observed in intestinal lactic acid bacteria among the groups (P>0.05). The experiment indicated that the prebiotic mannan oligosaccharide didn’t influence the growth performance in beluga juvenile and it is not appropriate for supplementation in the diet of this cultured species

GENETIC PARAMETERS FOR GROWTH PERFORMANCE TRAITS OF EGYPTIAN BARKI LAMBS USING RANDOM REGRESSION MODEL

Variance components and genetic parameters for growth traits were estimated for Barki lambs using the average information REMLF90 (AIREMLF90). A total of 3205 Barki lambs’ records over the period from 1984 to 2017 from experimental Borg Al-Arab station belonging to Animal Production Research Institute (APRI) were analyzed by fitting Random Regression Model (RRM) with Legendre polynomials (LPs) for body weight traits from birth up to 480 days. Gender, type of birth, year, season and age of dam were considered as fixed effects in addition to the fixed regression on Legendre polynomials, while random regression of additive genetic and permanent environmental effects were considered as random factors in the model. The results showed that all fixed factors and some interactions were significant for all studied traits (P<0.05). Quadratic equation was the best description for growth curve. Additive genetic and permanent environment variances ranged from 0.88 to 6.08 and from 0.88 to 15.33 for birth and thirteen months weights, respectively. Additive genetic and permanent environment covariances ranged from 0.05 to 16.06 and from 0.08 to 9.20 for birth with six months weights and for weaning with ten months weights, respectively. Direct and total heritabilities ranged from 0.05 to 0.41 and from 0.08 to 0.74 for four months and birth weights, respectively. Additive, genetic and phenotypic correlation coefficients were the lowest between birth weight with other studied traits and  the highest between ten months weight with other studied traits. Phenotypic variances were oscillated between 2.27 for birth weight to 22.56 for seven months weight, while, residual variances were oscillated between 0.06 for birth weight to 14.05 for four months weight. Therefore, ten months of age recommended to be the best criterion for selecting Egyptian Barki lambs for meat production

The survey of investigation about Mesopotamichthys sharpeyi projects in development program in Iranian Fisheries Research

Attention to the aquaculture capacity in inland water is needed to reach production of 262072 tons which was implicited in sixth economical and social development program of culture and production warmwater fishes industry. On of the most important aim of progressive management in fisheries program is native aquaculture activity with emphasis on Barbus fishes in Iran.Benni fish is one of the species of this genus despit of low relative growth rate, but is as a desire fishes in market. This fish not only has high fecondity and feed phytoplankton during the larval stages but also is very delicious for consumers. During the fifth economical and social development program there were so many projects have been done on aquaculture of this species but needs to analysis of all data which is important for successive future its aquaculture commercially. The precent analytical investigation base on three decades data, was done for completeing that gap including of analytical activities of researches were done, developmental access to fish aqu culture in six proficiency subjects , propagation and cultue, nutrition, genetic, health and disease biology, physiologt and determination of weak points. Then base on guideline studies on warmwater aquaculture and developmental road map, several suggestion for doing apply research were adopted

Genome-wide study of association and interaction with maternal cytomegalovirus infection suggests new schizophrenia loci.

Genetic and environmental components as well as their interaction contribute to the risk of schizophrenia, making it highly relevant to include environmental factors in genetic studies of schizophrenia. This study comprises genome-wide association (GWA) and follow-up analyses of all individuals born in Denmark since 1981 and diagnosed with schizophrenia as well as controls from the same birth cohort. Furthermore, we present the first genome-wide interaction survey of single nucleotide polymorphisms (SNPs) and maternal cytomegalovirus (CMV) infection. The GWA analysis included 888 cases and 882 controls, and the follow-up investigation of the top GWA results was performed in independent Danish (1396 cases and 1803 controls) and German-Dutch (1169 cases, 3714 controls) samples. The SNPs most strongly associated in the single-marker analysis of the combined Danish samples were rs4757144 in ARNTL (P=3.78 × 10(-6)) and rs8057927 in CDH13 (P=1.39 × 10(-5)). Both genes have previously been linked to schizophrenia or other psychiatric disorders. The strongest associated SNP in the combined analysis, including Danish and German-Dutch samples, was rs12922317 in RUNDC2A (P=9.04 × 10(-7)). A region-based analysis summarizing independent signals in segments of 100 kb identified a new region-based genome-wide significant locus overlapping the gene ZEB1 (P=7.0 × 10(-7)). This signal was replicated in the follow-up analysis (P=2.3 × 10(-2)). Significant interaction with maternal CMV infection was found for rs7902091 (P(SNP × CMV)=7.3 × 10(-7)) in CTNNA3, a gene not previously implicated in schizophrenia, stressing the importance of including environmental factors in genetic studies