Cerrahi Hemşirelerinin Cerrahi Alan İnfeksiyonlarını Önlemeye Yönelik Bilgi Düzeyleri

Giriş: Hemşirelerin cerrahi alan infeksiyonunu (CAİ) önlemek için doğru ve hızlı karar vermeleri ve kanıta dayalı uygulamalarla ilgili önerileri bilmeleri kaliteli hemşirelik bakımı verebilmek için çok önemlidir. Amaç: Bu araştırmanın amacı cerrahi hemşirelerinin CAİ önlenmesi konusundaki bilgi düzeylerini belirlemektir. Gereç ve Yöntem: Tanımlayıcı tipte planlanan araştırma, Ege Bölgesinde bir Eğitim Araştırma Hastanesi cerrahi kliniklerinde çalışan 58 hemşire ile 20 Ocak 2020-15 Şubat 2020 tarihleri arasında yapıldı. Veriler “Bireysel Özellikler Formu” ve Hastalık Kontrol ve Önleme Merkezleri 2017 güncel rehberine göre hazırlanmış “Cerrahi Alan İnfeksiyonunu Önlemeye Yönelik Bilgi Formu” ile toplandı. Çalışmada verilerin değerlendirilmesinde Tanımlayıcı istatistiksel metotlar ile birlikte Mann-Whitney U Testi, Kruskal-Wallis Testi, Lojistik Regresyon analizinden yararlanıldı. Bulgular: Çalışmaya katılan hemşirelerin; yaş ortalaması 40.2±6.1, %93.1’i (n=54) kadın, %82.8’i (n=48) evli, %93.1’i (n=54) lisans mezunu, %67.2’si (n=39) 16 yıl ve daha fazla süredir hemşirelik yapmaktadır. Araştırmaya katılan hemşirelerin %37.9’unun (n=22) infeksiyon kontrolü konusunda eğitim aldığı saptandı. Çalışmadan elde edilen verilere göre hemşirelerin “Cerrahi Alan İnfeksiyonu Önleme Bilgi Düzeyi” puan ortalaması 13.1±2.2 (min:7, max: 18), bilgi formunda yer alan ifadeleri doğru yanıtlama oranı ise ortalama %62.2±10.4 olarak hesaplandı. Sonuç: Hemşirelerin cerrahi alan infeksiyonlarını önlemeye ilişkin bilgi puan ortalaması orta seviyenin üstünde saptandı. Hemşirelerin cerrahi alan infeksiyonunun önlenmesi konusundaki yetkinliğini artırmak ve bilgi eksikliğini gidermek için güncel rehberler eşliğinde hizmet içi eğitim programları düzenlenmelidir

Maternal and neonatal outcomes of pregnant women with SARS-CoV-2 infection in our tertiary hospital

Objective: To evaluate clinical features, laboratory test results, and maternal and neonatal outcomes of pregnant patients with the Coronavirus disease (COVID-19). Methods: We reviewed clinical data from pregnant women with a laboratory-confirmed SARS-CoV-2, who were admitted to our university hospital in Türkiye. Demographic and clinical characteristics, laboratory test results, and maternal and neonatal outcomes were collected. Results: A total of 46 pregnant women were included in this study. The mean maternal age was 28 (min. 21 – max. 39) years and gestational age was 31 (min. 26 – max. 41) weeks. Two (4.37%) pregnant women were vaccinated with 1 dose of BioNTech® vaccine, and all other patients were unvaccinated. Shortness of breath was the most common symptom present in 15 cases (32.6%). Twenty-seven (58.69%) pregnant women gave birth in the preterm period, and 19 (41.30%) in the term period. Six (13.04%) pregnant women were followed up in the Anesthesia Intensive Care Unit. Two women with critical COVID-19 died in the postpartum period. Conclusion: COVID-19 infection has negative consequences in terms of maternal and neonatal outcomes. The most common causes of adverse neonatal outcomes are iatrogenic or spontaneous preterm births, while the most common causes of adverse maternal outcomes are prolonged hospitalization time, increased likelihood of intensive care hospitalization, and maternal deaths. The most effective way to prevent this situation is to get vaccinated regardless of trimester

Analysis of the common genetic component of large-vessel vasculitides through a meta- Immunochip strategy

Giant cell arteritis (GCA) and Takayasu's arteritis (TAK) are major forms of large-vessel vasculitis (LVV) that share clinical features. To evaluate their genetic similarities, we analysed Immunochip genotyping data from 1,434 LVV patients and 3,814 unaffected controls. Genetic pleiotropy was also estimated. The HLA region harboured the main disease-specific associations. GCA was mostly associated with class II genes (HLA-DRB1/HLA-DQA1) whereas TAK was mostly associated with class I genes (HLA-B/MICA). Both the statistical significance and effect size of the HLA signals were considerably reduced in the cross-disease meta-analysis in comparison with the analysis of GCA and TAK separately. Consequently, no significant genetic correlation between these two diseases was observed when HLA variants were tested. Outside the HLA region, only one polymorphism located nearby the IL12B gene surpassed the study-wide significance threshold in the meta-analysis of the discovery datasets (rs755374, P?=?7.54E-07; ORGCA?=?1.19, ORTAK?=?1.50). This marker was confirmed as novel GCA risk factor using four additional cohorts (PGCA?=?5.52E-04, ORGCA?=?1.16). Taken together, our results provide evidence of strong genetic differences between GCA and TAK in the HLA. Outside this region, common susceptibility factors were suggested, especially within the IL12B locus

Modeling of asphalt concrete via simulated annealing

WOS: 000275763700019In this study, 65 asphalt core specimens taken from D100/11 state highway section in Turkey were examined for their physical properties in the laboratory. Analysis of data was conducted to determine the effects of the varying environment temperature and varying length of exposure to these temperatures on the stability of the asphalt core samples using destructive, Marshall, method. The asphalt core samples were determined using SPSS statistical program for modeling. Simulated annealing was implemented to determine a set of unknown parameters which best matched the asphalt concrete model predictions with experimental data. This modeling procedure can be used as a guideline for experiments to improve the stability of the asphalt concrete. The stability of the asphalt concrete is taken as the main objective function with respect to voids of volume, saturated unit volume weight, air dry unit volume weight, environment temperature, and exposure time. (C) 2009 Elsevier Ltd. All rights reserved

Evaluation of the Psychological and Hormonal Parameters in Paragliding

Background. Paragliding is an extreme sport performed by gliding from a mountain at high altitude into the air. The authors aimed to determine the differences between the levels of adrenaline, cortisol, and insulin before and after the flight of tandem pilots and passengers flying for the first time, and to determine the relationship between these hormones and death anxiety and risk-taking levels. Materials and methods. The study included 12 experienced male pilots and 15 male passengers flying for the first time. Heart rate and blood pressure were measured after the participants had filled in Personal Information Form, DOSPERT Risk-Taking Scale and Death Anxiety Scale before the flight. Blood samples were taken before and after the flight to determine adrenaline, cortisol, and insulin levels. Results. Adrenaline and cortisol levels, as well as heart rate, increased significantly after the flight, while insulin levels decreased significantly in the passenger group (p < 0.05). There were no statistically significant differences in the pilot group. Conclusions. The experience factor plays an important role in the positive effect of paragliding flight on cortisol, adrenaline, insulin, and various physiological parameters, as well as mediates the adaptation of the organism to unusual situations. The human organism adapts physiologically and hormonally to the flying action. One of the striking results of the study was that cortisol levels were at the upper limit of normal values in the passenger group after the flight

Comparison of Orexin-A and neurofilament light chain levels in patients with relapsing-remitting multiple sclerosis: A pilot study = Orexin-A- és neurofilamentum-könnyűlánc fehérjeszintek relapszáló-remittáló sclerosis multiplexben szenvedőknél: pilot vizsgálat

Multiple sclerosis is an autoimmune disease of the central nervous system, with myelin degeneration and Relapsing-Remitting Multiple Sclerosis (RRMS) as the most common type. The aim of this study was to determine the levels of Neurofilament Light Chain (NFL) and Orexin-A (OXA) in patients with RRMS and compare it with healthy control subjects’ data. In this case-control study of 61 subjects, serum and cerebrospinal fluid samples were collected from 23 RRMS patients and 38 healthy control subjects. NFL and OXA levels were determined in cerebrospinal fluid and serum samples using enzyme-linked immunosorbent assay kits. Self-reported questionnaires were also administered to evaluate fatigue severity and impact. Receiver operating characteristic curve analysis was used to determine the optimal cut-off value of NFL and OXA. The NFL and OXA concentrations in cerebro­spinal fluid of RRMS patients were significantly higher than those of the control group (p < 0.001), but no sig­nificant difference was found in the serum concentrations (p = 0.842, p = 0.597, respectively). The cut-off values were found to be 1.194 ng/ml for NFL and 77.81 pg/ml for OXA in cerebrospinal fluid. A positive correlation was found between the Expanded Disability Status Scale and Epworth Sleepiness Scale in RRMS patients (ρ = 0.49, p = 0.045). These results suggest that increased levels of both NFL and OXA in cerebrospinal fluid reflect neuronal destruction in RRMS. Further research of neurodegeneration should focus on neuropeptides to determine the possible roles in RRMS pathogenesis

Experimental investigation and pseudoelastic truss model for in-plane behavior of corrugated sandwich panels with polyurethane foam core

Sandwich panels are commonly used in facades and the roofs of industrial buildings due to their well-known advantages. However, there is limited data about the in-plane behavior of the panels. Hence, this paper aimed to propose a pseudoelastic truss model to represent the effective in-plane stiffness and strength properties of the corrugated sandwich panels with a polyurethane foam core. Two separate sets of experiments (mock-up and system test) were conducted in the laboratory. The variables were the number of fasteners, sheet thickness, loading direction, and number of ribs. The number of fasteners, sheet thickness, and loading direction are the most effective parameters for the in-plane behavior. A formula was proposed to compute axial stiffness of the truss members by considering the effective parameters. Experimental results showed that the proposed robust truss model could give a good estimate of the pseudoelastic stiffness and maximum load bearing capacity of the sandwich panels.Turkish Precast Concrete AssociationThis study was conducted in the framework of ITuNOVA Technology Transfer Office Research Project titled Determination of In-plane Behavior of Corrugated Sandwich Panel Type Roof Shelters. The finan-cial support provided by Turkish Precast Concrete Association through this project is greatly appreciated. The study was conducted at the Structural and Earthquake Engineering Laboratory (STEELab) of Istanbul Technical University. Support of the laboratory staff and the contributions of Gunkut Barka and Hakan Atakody are gratefully acknowledged