Enhanced removal of 8-quinolinecarboxylic acid in an activated carbon cloth by electroadsorption in aqueous solution

The effect of the electrochemical treatment (potentiostatic treatment in a filter-press electrochemical cell) on the adsorption capacity of an activated carbon cloth (ACC) was analyzed in relation with the removal of 8-quinolinecarboxylic acid pollutant from water. The adsorption capacity of an ACC is quantitatively improved in the presence of an electric field (electroadsorption process) reaching values of 96% in comparison to 55% in absence of applied potential. In addition, the cathodic treatment results in higher removal efficiencies than the anodic treatment. The enhanced adsorption capacity has been proved to be irreversible, since the removed compound remains adsorbed after switching the applied potential. The kinetics of the adsorption processes is also improved by the presence of an applied potential. (C) 2015 Elsevier Ltd. All rights reserved.Grateful acknowledgement is made to Ministerio de Economia y Competitividad (MAT2013-42007-P, JCI-2012-12664) and Generalitat Valenciana (Prometeo/2013/038) for the financial support.López-Bernabeu, S.; Ruiz-Rosas, R.; Quijada Tomás, C.; Montilla, F.; Morallón, E. (2016). Enhanced removal of 8-quinolinecarboxylic acid in an activated carbon cloth by electroadsorption in aqueous solution. Chemosphere. 144:982-988. https://doi.org/10.1016/j.chemosphere.2015.09.071S98298814

La Piedra de Novelda: una roca muy utilizada en el patrimonio arquitectónico

Novelda Stone is a calcareous rock, of the biocalcarenite type. It is extracted from the «Vinalopó Medio» area (Alicante, eastern Spain). Novelda stone is known as construction material from the 13th century. From final of the 19th century until the present time, it has been used in Madrid, Valencia and Alicante. In the past, the main quarries from which this type of rock was extracted were located in the municipal districts of Monóvar (Almorquí Stone), Sax (Portazgo Stone) and Elda (Bateig Stone). Nowadays, the main active extraction site is situated in the Bateig Hill quarries. The rock extracted is known commercially as Bateig Stone. The main varieties of this Bateig Stone are: White, Blue, Layer and Fantasy. Each variety of Novelda stone has different durability rate and different pathology depending on their characteristics, particularly on their hydric behaviour patterns. Layer Bateig and Portazgo stone undergo granular disintegration and alveolization and are less durable than the rest. White and Blue Bateig, as well as Almorquí stone, only develop fissures or scaling under extreme conditions.La Piedra de Novelda es una roca carbonática del tipo biocalcarenita. Se extrae del área de Vinalopó Medio (Alicante, España oriental). La piedra de Novelda es conocida como material de construcción desde el siglo XIII. Desde finales del siglo XIX hasta la actualidad, se ha utilizado en edificios y monumentos de Madrid y Valencia, así como Alicante. En el pasado, las canteras principales donde se extrajo este tipo de piedra se localizaban en los distritos municipales de Monóvar (Piedra Almorquí), Sax (Piedra Portazgo) y El da (Piedra Bateig). Hoy en día, la actividad principal se sitúa en las canteras de Bateig. La piedra extraída es conocida comercialmente como Piedra Bateig. Las variedades principales de esta Piedra Bateig son: Blanco, Azul, Llano y Fantasía. Consecuencia de las diferentes propiedades y en especial de los diferentes comportamientos hídricos, la durabilidad de los distintos tipos de Piedra de Novelda y sus patologías son diferentes. La Bateig LLano y la Piedra de Portazgo sufren desagregación granular y alveolización y su durabilidad es menor que la del resto de las variedades. La Bateig Blanco y Bateig Azul, junto con la Piedra Almorquí, sólo en condiciones muy extremas llegan a desarrollar fisuraciones y/o descamaciones

The chemical and electrochemical oxidative polymerization of 2-amino-4-tert-butylphenol

[EN] Poly(2-amino-4-tert-butylphenol), poly(2A-4TBP), was synthesized from monomer aqueous solution using either electrochemical or chemical oxidation procedures. Several spectroscopic characterization techniques were employed to gain information on the chemical structure and redox behavior of the obtained materials. It was found that the chemical polymerization product could be described as an oligomer mixture containing up to 16 monomer units. In parallel to other polymers derived from o-aminophenol, phenoxazine rings constitute also the basic structure of poly(2A-4TBP). In addition, the occurrence of N-N couplings, which are favored by the presence of the voluminous tert-butyl substituent, seems also relevant. No significant structural differences were found between the chemically or electrochemically synthesized materials. © 2016 Published by Elsevier Ltd.Financial support from the Spanish Ministerio de Economía y Competitividad and FEDER funds (MAT2013-42007-P) and from the Generalitat Valenciana (PROMETEO2013/038) is gratefully acknowledged. M. Abidi thanks the Ministry of Higher Education and Scientific Research of Tunisia for funding her stay at the University of Alicante.Abidi, M.; López-Bernabeu, S.; Huerta, F.; Montilla-Jiménez, F.; Besbes-Hentati, S.; Morallón, E. (2016). The chemical and electrochemical oxidative polymerization of 2-amino-4-tert-butylphenol. Electrochimica Acta. 212:958-965. https://doi.org/10.1016/j.electacta.2016.07.060S95896521

θ13\theta_{13}, δ\delta and the neutrino mass hierarchy at a γ=350\gamma=350 double baseline Li/B β\beta-Beam

We consider a $\beta$-Beam facility where $^8$Li and $^8$B ions are accelerated at $\gamma = 350$, accumulated in a 10 Km storage ring and let decay, so as to produce intense $\bar \nu_e$ and $\nu_e$ beams. These beams illuminate two iron detectors located at $L \simeq 2000$ Km and $L \simeq 7000$ Km, respectively. The physics potential of this setup is analysed in full detail as a function of the flux. We find that, for the highest flux ($10 \times 10^{18}$ ion decays per year per baseline), the sensitivity to $\theta_{13}$ reaches $\sin^2 2 \theta_{13} \geq 2 \times10^{-4}$; the sign of the atmospheric mass difference can be identified, regardless of the true hierarchy, for $\sin^2 2 \theta_{13} \geq 4\times10^{-4}$; and, CP-violation can be discovered in 70% of the $\delta$-parameter space for $\sin^2 2 \theta_{13} \geq 10^{-3}$, having some sensitivity to CP-violation down to $\sin^2 2 \theta_{13} \geq 10^{-4}$ for $|\delta| \sim 90^\circ$.Comment: 35 pages, 20 figures. Minor changes, matches the published versio

Peripheral Inflammatory Indexes Neutrophil/Lymphocyte Ratio (NLR) and Red Cell Distribution Width (RDW) as Prognostic Biomarkers in Advanced Solitary Fibrous Tumour (SFT) Treated with Pazopanib

Simple Summary Pazopanib treatment in advanced solitary fibrous tumour patients, assessed in the prospective GEIS-32 phase II clinical trial, has shown longer progression-free survival and overall survival versus chemotherapy treatment in control patients. In recent years, the interest in the prognostic and predictive value of different peripheral inflammatory indexes, such as neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, and red cell distribution width, has been increased in sarcomas, showing significant results in different soft tissue sarcomas. However, they have not been previously analysed in solitary fibrous tumour (SFT) patients. These indexes were retrospectively analysed in the typical- and malignant-SFT cohorts treated with pazopanib of the GEIS-32 trial to evaluate their predictive or prognostic value. Pazopanib was assessed prospectively in the GEIS-32 phase II study (NCT02066285) on advanced solitary fibrous tumour (SFT), resulting in a longer progression-free survival (PFS) and overall survival (OS) compared with historical controls treated with chemotherapy. A retrospective analysis of peripheral inflammatory indexes in patients enrolled into GEIS-32 was performed to evaluate their prognostic and predictive value. Patients received pazopanib 800 mg/day as the first antiangiogenic line. The impacts of baseline neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), and red cell distribution width (RDW) on PFS, OS, and Choi response were evaluated by univariate and multivariate analysis. Metastasis-free interval (MFI), mitotic count, and ECOG were also included as potential prognostic factors. Sixty-seven SFT patients, enrolled in this study, showed a median age of 63 years and a female/male distribution of 57/43. The median follow-up from treatment initiation was 16.8 months. High baseline NLR, PLR, and standardised RDW were significantly associated with worse PFS and OS. NLR, RDW, MFI, and mitotic count were independent variables for PFS, while RDW and ECOG were independent for OS. Further, NLR and mitotic count were independent factors for Choi response. High baseline NLR and RDW values were independent prognostic biomarkers for worse outcome in advanced SFT patients treated with pazopanib

Hidratos de gas marinos: ¿un recurso futuro de gas natural para Europa? M.

Los hidratos de gas son compuestos cristalinos donde una molécula de gas, principalmente metano, queda atrapada en una red de moléculas de agua en forma de hielo. La importancia de los hidratos de gas en la naturaleza es muy alta ya que constituye una fuente alternativa de energía y a su vez juegan un papel importante en el delicado equilibrio del clima a nivel global y en los riesgos geológicos en el ámbito marino. La acción COST MIGRATE está diseñada con el fin de integrar la experiencia de un gran número de grupos de investigación europeos y agentes del sector para promover el desarrollo de conocimientos multidisciplinarios sobre el potencial de los hidratos de gas como fuente de energía en Europa. Dos de los objetivos de esta acción son realizar un inventario europeo de hidratos de gas explotables y evaluar los riesgos ambientales. En este trabajo se muestran los principales indicios de hidratos de gas en los márgenes europeos incluida la Península Ibérica, con una primera aproximación sobre el espesor y situación de la zona de estabilidad de hidratos de gas en el margen Ibérico.Gas hydrates are crystalline compounds where a molecule of gas, mainly methane, is trapped in a cage of icewater molecules. The importance of gas hydrates in nature is very high because it is an alternative source of energy and play a major role in the delicate balance of the global climate and in the marine geological risks. MIGRATE COST action is designed to integrate the experience of a large number of European research groups and industrial players to promote the development of multidisciplinary knowledge on the potential of gas hydrates as energy resource in Europe. Two of the objectives of the action aim to estimate the European inventory of exploitable gas hydrates and to assess environmental risks. In this work we show the occurrences of gas hydrates described in European margins including the Iberian Peninsula, with a first approximation on the thickness and location of the area of stability of gas hydrates in the Iberian margin.COST Action ES1405 (MIGRATE)Versión del edito

Relationships between heavy metal concentrations in three different body fluids and male reproductive parameters: a pilot study

<p>Abstract</p> <p>Background</p> <p>Animal studies have shown the reproductive toxicity of a number of heavy metals. Very few human observational studies have analyzed the relationship between male reproductive function and heavy metal concentrations in diverse biological fluids.</p> <p>Methods</p> <p>The current study assessed the associations between seminal and hormonal parameters and the concentration of the 3 most frequent heavy metal toxicants (lead, cadmium and mercury) in three different body fluids. Sixty one men attending infertility clinics that participated in a case-control study to explore the role of environmental toxins and lifestyles on male infertility were analyzed. Concentration of lead, cadmium and mercury were measured in blood and seminal plasma and whole blood using anodic stripping voltammetry and atomic absorption spectrophotometry. Serum samples were analyzed for follicle-stimulating hormone, luteinizing hormone and testosterone. Semen analyses were performed according to World Health Organization criteria. Mann-Whitney test and Spearman's rank correlations were used for unadjusted analyses. Multiple linear regression models were performed controlling for age, body mass index and number of cigarettes per day.</p> <p>Results</p> <p>There were no significant differences between cases and controls in the concentrations of heavy metals in any of the three body fluids. In multivariate analyses using all subjects no significant associations were found between serum hormone levels and metal concentrations. However there was a significant positive association between the percentage of immotile sperms and seminal plasma levels of lead and cadmium.</p> <p>Conclusions</p> <p>Our results suggest that the presence of lead and cadmium in the reproductive tract of men may be related to a moderate alteration of their seminal parameters.</p

The Mesolithic-Neolithic transition in southern Iberia

New data and a review of historiographic information from Neolithic sites of the Malaga and Algarve coasts (southern Iberian Peninsula) and from the Maghreb (North Africa) reveal the existence of a Neolithic settlement at least from 7.5 cal ka BP. The agricultural and pastoralist food producing economy of that population rapidly replaced the coastal economies of the Mesolithic populations. The timing of this population and economic turnover coincided with major changes in the continental and marine ecosystems, including upwelling intensity, sea-level changes and increased aridity in the Sahara and along the Iberian coast. These changes likely impacted the subsistence strategies of the Mesolithic populations along the Iberian seascapes and resulted in abandonments manifested as sedimentary hiatuses in some areas during the Mesolithic-Neolithic transition. The rapid expansion and area of dispersal of the early Neolithic traits suggest the use of marine technology. Different evidences for a Maghrebian origin for the first colonists have been summarized. The recognition of an early North-African Neolithic influence in Southern Iberia and the Maghreb is vital for understanding the appearance and development of the Neolithic in Western Europe. Our review suggests links between climate change, resource allocation, and population turnover. (C) 2011 University of Washington. Published by Elsevier Inc. All rights reserved.Fundacao para a Ciencia e a Tecnologia (Portugal); European Science Foundation [PTDC/HAH/64548/2006]; European Union; Fundacao para a Ciencia e Tecnologia; Ministerio de Ciencia e Innovacion, Spain [HAR 2008-1920, CGL2009-07603, CTM2009-07715, CSD2006-00041, HAR2008-06477-C03-03/HIST]; European Research Council [2008-AdG 230561]; MARM [200800050084447]; Project RNM [05212]; Junta de Andalucia, Spain [0179]; FCT [SFRH/BPD/26525/2006]; CSIC "JAE-Doc"info:eu-repo/semantics/publishedVersio

New insights into the neolithisation process in southwest Europe according to spatial density analysis from calibrated radiocarbon dates

The agricultural way of life spreads throughout Europe via two main routes: the Danube corridor and the Mediterranean basin. Current archaeological literature describes the arrival to the Western Mediterranean as a rapid process which involves both demic and cultural models, and in this regard, the dispersal movement has been investigated using mathematical models, where the key factors are time and space. In this work, we have created a compilation of all available radiocarbon dates for the whole of Iberia, in order to draw a chronological series of maps to illustrate temporal and spatial patterns in the neolithisation process. The maps were prepared by calculating the calibrated 14C date probability density curves, as a proxy to show the spatial dynamics of the last hunter-gatherers and first farmers. Several scholars have pointed out problems linked with the variability of samples, such as the overrepresentation of some sites, the degree of regional research, the nature of the dated samples and above all the archaeological context, but we are confident that the selected dates, after applying some filters and statistical protocols, constitute a good way to approach settlement spatial patterns in Iberia at the time of the neolithisation process

A longitudinal study of gene expression in first-episode schizophrenia; exploring relapse mechanisms by co-expression analysis in peripheral blood

Little is known about the pathophysiological mechanisms of relapse in first-episode schizophrenia, which limits the study of potential biomarkers. To explore relapse mechanisms and identify potential biomarkers for relapse prediction, we analyzed gene expression in peripheral blood in a cohort of first-episode schizophrenia patients with less than 5 years of evolution who had been evaluated over a 3-year follow-up period. A total of 91 participants of the 2EPs project formed the sample for baseline gene expression analysis. Of these, 67 provided biological samples at follow-up (36 after 3 years and 31 at relapse). Gene expression was assessed using the Clariom S Human Array. Weighted gene co-expression network analysis was applied to identify modules of co-expressed genes and to analyze their preservation after 3 years of follow-up or at relapse. Among the 25 modules identified, one module was semi-conserved at relapse (DarkTurquoise) and was enriched with risk genes for schizophrenia, showing a dysregulation of the TCF4 gene network in the module. Two modules were semi-conserved both at relapse and after 3 years of follow-up (DarkRed and DarkGrey) and were found to be biologically associated with protein modification and protein location processes. Higher expression of DarkRed genes was associated with higher risk of suffering a relapse and early appearance of relapse (p = 0.045). Our findings suggest that a dysregulation of the TCF4 network could be an important step in the biological process that leads to relapse and suggest that genes related to the ubiquitin proteosome system could be potential biomarkers of relapse. © 2021, The Author(s)