La comunicación de marketing en la empresa Glow Nail & Salón, Los Olivos - 2014

La comunicación de marketing en la empresa Glow nail & salón, Los Olivos en el año 2014, es el resultado de un estudio que planteó como objetivo el Establecer el nivel de la comunicación de marketing en la empresa Glow nail & salón, Los Olivos en el año 2014; esto a razón de que se deseaba determinar cual era el nivel de la comunicación de marketing hacia los clientes, por lo que el estudio se enfocó en el comportamiento de la comunicación de marketing, basándose en los estudios de Philip Kotler & Kevin Keller, del cual se determinó las dimensiones que la conforman, como son, la publicidad, promoción de ventas, marketing de boca en boca, marketing directo y ventas personales, con respecto a la metodología empleada se desarrolló bajo el tipo de investigación descriptiva, porque nos permitió describir y analizar las reacciones y percepciones que generan las herramientas de la comunicación de marketing en los clientes; así mismo, se trabajó bajo un diseño de investigación no experimental con una metodología cuantitativo Inductivo - Deductivo, para la obtención de los resultados se implemento el desarrollo del cuestionario a través de la técnica de la encuesta y la observación, en una población de 80 personas, todas ellas clientes directos de la empresa, lo que nos dio como resultados que los clientes perciben que la comunicación de marketing tiene tendencia al nivel medianamente óptimo, por tanto, podemos concluir que existe la necesidad de dar mayor efectividad a los medios publicitarios y mejora el nivel de comunicación hacia los clientes

Interannual variability of the tropical Atlantic independent of and associated with ENSO: Part I. The North Tropical Atlantic

The interannual variability of the tropical Atlantic ocean-atmosphere system is examined using 50 years of sea-surface temperature (SST) and re-analysis data, and satellite data when available. A singular value decomposition analysis of 12- to 72-month bandpass filtered SST and zonal wind stress reveals two dominant modes of interannual variability. The SST anomalies are confined to the North Tropical Atlantic (NTA) in the first mode and extend over the equatorial and South Tropical Atlantic in the second mode. No evidence is found for an Atlantic SST dipole. The structure of the first (NTA) mode is examined in detail here, while the second mode has been described in a companion paper. In particular, the relationship of the NTA mode with El Nino-Southern Oscillation (ENSO) is investigated. There are 12 NTA events (seven warm and five cold) that are associated with ENSO, and 18 NTA events (seven warm and 11 cold) that are independent of ENSO. The ENSO-associated NTA events appear to be a passive response to remote ENSO forcing, mainly via a Pacific-North America (PNA)-like wave train that induces SST anomalies over the NTA through changes in the surface wind and latent heat flux. The NTA anomalies peak four months after ENSO. There does not appear to be an atmospheric response to the NTA SST anomalies as convection over the Atlantic is suppressed by the anomalous Walker circulation due to ENSO. The ENSO-independent NTA events also appear to be induced by an extratropical wave train from the Pacific sector (but one that is independent of Pacific SST), and forcing by the North Atlantic Oscillation (NAO) also contributes. As the event matures, the atmosphere does respond to the NTA SST anomalies, with enhanced convection over the Caribbean and a wave train that propagates northeastward to Europe

La Agrofísica en los planes de estudio de Ingeniería Agrícola

Para todo país resulta necesaria la actualización de los currículos de estudio en las ramas agrícolas para que de esta manera corresponda mejor con las demandas del País y el desarrollo esperado en el sector agro industrial. Un aspecto importante, contenido en todos los planes de estudio de Ingeniería Agrícola es la Agrofísica. En este trabajo se discute sobre el significado del término Agrofísica y se analiza su presencia en los planes de estudios en ingeniería agrícola de 36 países. Por último se discuten las principales tendencia observadas y se compara con los planes de Ingeniería Agrícola en CubaEje: Educación Universitaria ReflexionesRed de Universidades con Carreras en Informática (RedUNCI

PENGARUH PERILAKU PEMERIKSA PAJAK DAN PROFESIONALISME PEMERIKSA PAJAK TERHADAP KINERJA PEMERIKSA PAJAK (Studi Pada KPP Pratama Bandung Karees )

ABSTRAK Penelitian ini bertujuan untuk mengetahui seberapa besar pengaruh perilaku pemeriksa pajak terhadap profesionalisme pemeriksa pajak dampaknya pada kinerja pemeriksa pajak dan untuk mengetahui seberapa besar pengaruh perilaku pemeriksa pajak dan profesionalisme pemeriksa pajak terhadap kinerja pemeriksa pajak . Metode penelitian yang digunakan adalah analisis deskriptif dan verifikatif. Populasi dari penelitian ini adalah pemeriksa pajak di KPP Pratama Bandung Karees yang berjumlah 30 responden. Te knik sampling yang digunakan adalah teknik sampling jenuh yaitu keseluruhan populasi dijadikan sampel penelitian. Analisis data dilakukan dengan menggunakan analisis path dan analisis regresi linier berganda. Hasil penelitian menunju k kan bahwa Perilaku Pemeriksa Pajak masuk ke dalam Kriteria cukup baik karena nilai rata - rata sebesar 33,77 berada pada interval 26,1 s/d 34. Secara parsial Perilaku Pemeriksa Pajak berpengaruh signifikan terhadap Kinerja Pemeriksa Pajak dengan kontribusi pengaruh sebesar 21, 6%. Profesionalisme Pemeriksa Pajak masuk ke dalam Kriteria cukup tinggi karena nilai rata - rata sebesar 47,8 berada pada interval 36,6 s/d 47,8 . Secara parsial Profesionalisme Pemeriksa Pajak berpengaruh signifikan terhadap Kinerja Pemeriksa Pajak dengan k ontribusi pengaruh sebesar 37,2%. Secara simultan Pengaruh Perilaku Pemeriksa Pajak dan Profesionalisme Pemeriksa Pajak terhadap Kinerja Pemeriksa Pajak adalah Perilaku Pemeriksa Pajak dan Profesionalisme Pemeriksa Pajak berpengaruh signifikan terhadap K inerja Pemeriksa Pajak dengan kontribusi pengaruh sebesar 59%. Pengaruh tidak langsung Perilaku Pemeriksa Pajak terhadap Kinerja Pemeriksa Pajak melalui Profesionalisme Pemeriksa Pajak sebesar 26,3%. Total pengaruh Perilaku Pemeriksa Pajak, Profesionalism e Pemeriksa Pajak terhadap Kinerja Pemeriksa Pajak sebesar 47,9%. Kata kunci : Perilaku Pemeriksa Pajak , Profesionalisme Pemeriksa Pajak dan Kinerja Pemeriksa Pajak

Effects of ammonium nitrate, cesium chloride and tetraethylammonium on high-affinity potassium uptake in habanero pepper plantlets (Capsicum chinense Jacq.)

Potassium (K+) is an essential nutrient and the most abundant cation in plant cells. Plants have a wide variety of transport systems for K+ acquisition that catalyze K+ uptake across a wide spectrum of external K+ concentrations and mediate K+ movement within the plant, as well as its release into the environment. The KUP/HAK/KT transporter family plays a key role in K+ homeostasis in plant cells. The present study demonstrates that habanero pepper plantlets have a clear pattern of K+ uptake when resupplemented with K+ after K+ starvation. Habanero pepper plantlets, re-supplemented with a solution containing low concentrations of K+ after 72, 96 or 120 h of K+ starvation were able to decrease the amount of K+ in the solution at different time points. To study the effect of NH4+, we added different concentrations of NH4NO3 to the medium solution and demonstrated that NH4+ inhibited K+ uptake in a dose-dependent manner. When the plantlets were subjected to K+ starvation for 72 h and then resupplemented with 50 or 100 μM K+, exposure to K+ channel blockers (10 mM CsCl and 20 mM TEA) decreased their K+ uptake compared with the control treatment. A model demonstrating the process of K+ uptake through an NH4+-insensitive component was proposed.Key words: Potassium, high affinity transporters, channel blockers, ammonium

Aβ43 aggregates exhibit enhanced prion-like seeding activity in mice.

When injected into genetically modified mice, aggregates of the amyloid-β (Aβ) peptide from the brains of Alzheimer's disease (AD) patients or transgenic AD mouse models seed cerebral Aβ deposition in a prion-like fashion. Within the brain, Aβ exists as a pool of distinct C-terminal variants with lengths ranging from 37 to 43 amino acids, yet the relative contribution of individual C-terminal Aβ variants to the seeding behavior of Aβ aggregates remains unknown. Here, we have investigated the relative seeding activities of Aβ aggregates composed exclusively of recombinant Aβ38, Aβ40, Aβ42, or Aβ43. Cerebral Aβ42 levels were not increased in AppNL-F knock-in mice injected with Aβ38 or Aβ40 aggregates and were only increased in a subset of mice injected with Aβ42 aggregates. In contrast, significant accumulation of Aβ42 was observed in the brains of all mice inoculated with Aβ43 aggregates, and the extent of Aβ42 induction was comparable to that in mice injected with brain-derived Aβ seeds. Mice inoculated with Aβ43 aggregates exhibited a distinct pattern of cerebral Aβ pathology compared to mice injected with brain-derived Aβ aggregates, suggesting that recombinant Aβ43 may polymerize into a unique strain. Our results indicate that aggregates containing longer Aβ C-terminal variants are more potent inducers of cerebral Aβ deposition and highlight the potential role of Aβ43 seeds as a crucial factor in the initial stages of Aβ pathology in AD

Implementation of higher-order absorbing boundary conditions for the Einstein equations

We present an implementation of absorbing boundary conditions for the Einstein equations based on the recent work of Buchman and Sarbach. In this paper, we assume that spacetime may be linearized about Minkowski space close to the outer boundary, which is taken to be a coordinate sphere. We reformulate the boundary conditions as conditions on the gauge-invariant Regge-Wheeler-Zerilli scalars. Higher-order radial derivatives are eliminated by rewriting the boundary conditions as a system of ODEs for a set of auxiliary variables intrinsic to the boundary. From these we construct boundary data for a set of well-posed constraint-preserving boundary conditions for the Einstein equations in a first-order generalized harmonic formulation. This construction has direct applications to outer boundary conditions in simulations of isolated systems (e.g., binary black holes) as well as to the problem of Cauchy-perturbative matching. As a test problem for our numerical implementation, we consider linearized multipolar gravitational waves in TT gauge, with angular momentum numbers l=2 (Teukolsky waves), 3 and 4. We demonstrate that the perfectly absorbing boundary condition B_L of order L=l yields no spurious reflections to linear order in perturbation theory. This is in contrast to the lower-order absorbing boundary conditions B_L with L<l, which include the widely used freezing-Psi_0 boundary condition that imposes the vanishing of the Newman-Penrose scalar Psi_0.Comment: 25 pages, 9 figures. Minor clarifications. Final version to appear in Class. Quantum Grav

Altering the Coordination of Iron Porphyrins by Ionic Liquid Nanodomains in Mixed Solvent Systems

The solvent environment around iron porphyrin complexes was examined using mixed molecular/RTIL (room temperature ionic liquid) solutions. The formation of nanodomains in these solutions provides different solvation environments for substrates that could have significant impact on their chemical reactivity. Iron porphyrins (Fe(P)), whose properties are sensitive to solvent and ligation changes, were used to probe the molecular/RTIL environment. The addition of RTILs to molecular solvents shifted the redox potentials to more positive values. When there was no ligation change upon reduction, the shift in the E° values were correlated to the Gutmann acceptor number, as was observed for other porphyrins with similar charge changes. As %RTIL approached 100 %, there was insufficient THF to maintain coordination and the E° values were much more dependent upon the %RTIL. In the case of FeIII(P)(Cl), the shifts in the E° values were driven by the release of the chloride ion and its strong attraction to the ionic liquid environment. The spectroscopic properties and distribution of the FeII and FeI species into the RTIL nanodomains were monitored with visible spectroelectrochemistry, 19F NMR and EPR spectroscopy. This investigation shows that coordination and charge delocalization (metal versus ligand) in the metalloporphyrins redox products can be altered by the RTIL fraction in the solvent system, allowing an easy tuning of their chemical reactivity

Vpu Antagonizes BST-2–Mediated Restriction of HIV-1 Release via β-TrCP and Endo-Lysosomal Trafficking

The interferon-induced transmembrane protein BST-2/CD317 (tetherin) restricts the release of diverse enveloped viruses from infected cells. The HIV-1 accessory protein Vpu antagonizes this restriction by an unknown mechanism that likely involves the down-regulation of BST-2 from the cell surface. Here, we show that the optimal removal of BST-2 from the plasma membrane by Vpu requires the cellular protein β-TrCP, a substrate adaptor for a multi-subunit SCF E3 ubiquitin ligase complex and a known Vpu-interacting protein. β-TrCP is also required for the optimal enhancement of virion-release by Vpu. Mutations in the DSGxxS β-TrCP binding-motif of Vpu impair both the down-regulation of BST-2 and the enhancement of virion-release. Such mutations also confer dominant-negative activity, consistent with a model in which Vpu links BST-2 to β-TrCP. Optimal down-regulation of BST-2 from the cell surface by Vpu also requires the endocytic clathrin adaptor AP-2, although the rate of endocytosis is not increased; these data suggest that Vpu induces post-endocytic membrane trafficking events whose net effect is the removal of BST-2 from the cell surface. In addition to its marked effect on cell-surface levels, Vpu modestly decreases the total cellular levels of BST-2. The decreases in cell-surface and intracellular BST-2 are inhibited by bafilomycin A1, an inhibitor of endosomal acidification; these data suggest that Vpu induces late endosomal targeting and partial degradation of BST-2 in lysosomes. The Vpu-mediated decrease in surface expression is associated with reduced co-localization of BST-2 and the virion protein Gag along the plasma membrane. Together, the data support a model in which Vpu co-opts the β-TrCP/SCF E3 ubiquitin ligase complex to induce endosomal trafficking events that remove BST-2 from its site of action as a virion-tethering factor