77 research outputs found
Controlling Soil Crusting with Phosphoric Acid
Soil crusting is often a serious problem in obtaining
adequate and uniform sugarbeet stands in many areas of
Idaho. Poor stands often necessitate reseeding or seeding
to another crop.
A promising method has been developed to prevent
soil crusting on the Panned soil series in southern Idaho.
Agricultural grade phosphoric acid, which is available
through many liquid fertilizer outlets, is diluted to 12-
24% -phosphoric acid solution, and sprayed in 3-inch
bands on the seeded sugarbeet row directly behind the
planter. The chemical reactions between the soil components
and the acid prevent the soil in the bands from
crusting, but do not injure the seedlings
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Large scale steam valve test: Performance testing of large butterfly valves and full scale high flowrate steam testing
This report presents the results of the design testing of large (36-inch diameter) butterfly valves under high flow conditions. The two butterfly valves were pneumatically operated air-open, air-shut valves (termed valves 1 and 2). These butterfly valves were redesigned to improve their ability to function under high flow conditions. Concern was raised regarding the ability of the butterfly valves to function as required with high flow-induced torque imposed on the valve discs during high steam flow conditions. High flow testing was required to address the flow-induced torque concerns. The valve testing was done using a heavily instrumented piping system. This test program was called the Large Scale Steam Valve Test (LSSVT). The LSSVT program demonstrated that the redesigned valves operated satisfactorily under high flow conditions
Counteractive effects of antenatal glucocorticoid treatment on D1 receptor modulation of spatial working memory.
RATIONALE: Antenatal exposure to the glucocorticoid dexamethasone dramatically increases the number of mesencephalic dopaminergic neurons in rat offspring. However, the consequences of this expansion in midbrain dopamine (DA) neurons for behavioural processes in adulthood are poorly understood, including working memory that depends on DA transmission in the prefrontal cortex (PFC). OBJECTIVES: We therefore investigated the influence of antenatal glucocorticoid treatment (AGT) on the modulation of spatial working memory by a D1 receptor agonist and on D1 receptor binding and DA content in the PFC and striatum. METHODS: Pregnant rats received AGT on gestational days 16-19 by adding dexamethasone to their drinking water. Male offspring reared to adulthood were trained on a delayed alternation spatial working memory task and administered the partial D1 agonist SKF38393 (0.3-3 mg/kg) by systemic injection. In separate groups of control and AGT animals, D1 receptor binding and DA content were measured post-mortem in the PFC and striatum. RESULTS: SKF38393 impaired spatial working memory performance in control rats but had no effect in AGT rats. D1 binding was significantly reduced in the anterior cingulate cortex, prelimbic cortex, dorsal striatum and ventral pallidum of AGT rats compared with control animals. However, AGT had no significant effect on brain monoamine levels. CONCLUSIONS: These findings demonstrate that D1 receptors in corticostriatal circuitry down-regulate in response to AGT. This compensatory effect in D1 receptors may result from increased DA-ergic tone in AGT rats and underlie the resilience of these animals to the disruptive effects of D1 receptor activation on spatial working memory.The authors’ research is funded by the Wellcome
Trust (grant number 086871/Z/08/Z), the MRC (G0701500), a joint
award from the MRC (G1000183) and Wellcome Trust (093875/Z/10/
Z) in support of the Behavioral and Clinical Neuroscience Institute at
Cambridge University, and an MRC strategic award to the Imperial
College-Cambridge University-Manchester University (ICCAM) addiction
cluster (G1000018).This is the final version of the article. It first appeared from Springer at http://dx.doi.org/10.1007/s00213-016-4405-8
Sex-dependent diversity in ventral tegmental dopaminergic neurons and developmental programing: a molecular, cellular and behavioral analysis
The knowledge that diverse populations of dopaminergic neurons within the ventral tegmental area (VTA) can be distinguished in terms of their molecular, electrophysiological and functional properties, as well as their differential projections to cortical and subcortical regions has significance for key brain functions, such as the regulation of motivation, working memory and sensorimotor control. Almost without exception, this understanding has evolved from landmark studies performed in the male sex. However, converging evidence from both clinical and pre-clinical studies illustrates that the structure and functioning of the VTA dopaminergic systems are intrinsically different in males and females. This may be driven by sex differences in the hormonal environment during adulthood ('activational' effects) and development (perinatal and/or pubertal 'organizational' effects), as well as genetic factors, especially the SRY gene on the Y chromosome in males, which is expressed in a sub-population of adult midbrain dopaminergic neurons. Stress and stress hormones, especially glucocorticoids, are important factors which interact with the VTA dopaminergic systems in order to achieve behavioral adaptation and enable the individual to cope with environmental change. Here, also, there is male/female diversity not only during adulthood, but also in early life when neurobiological programing by stress or glucocorticoid exposure differentially impacts dopaminergic developmental trajectories in male and female brains. This may have enduring consequences for individual resilience or susceptibility to pathophysiological change induced by stressors in later life, with potential translational significance for sex bias commonly found in disorders involving dysfunction of the mesocorticolimbic dopaminergic systems. These findings highlight the urgent need for a better understanding of the sexual dimorphism in the VTA if we are to improve strategies for the prevention and treatment of debilitating conditions which differentially affect men and women in their prevalence and nature, including schizophrenia, attention/deficit hyperactivity disorder, autism spectrum disorders, anxiety, depression and addiction
Controlling Soil Crusting with Phosphoric Acid
Soil crusting is often a serious problem in obtaining
adequate and uniform sugarbeet stands in many areas of
Idaho. Poor stands often necessitate reseeding or seeding
to another crop.
A promising method has been developed to prevent
soil crusting on the Panned soil series in southern Idaho.
Agricultural grade phosphoric acid, which is available
through many liquid fertilizer outlets, is diluted to 12-
24% -phosphoric acid solution, and sprayed in 3-inch
bands on the seeded sugarbeet row directly behind the
planter. The chemical reactions between the soil components
and the acid prevent the soil in the bands from
crusting, but do not injure the seedlings
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