Abonos obtenidos del compostado de heces de ganado bovino de leche vs. fertilizante en la producción de triticale (X Triticum secale Wittmack)

The use of compost obtained from feces is increasingly common in agriculture for soil fertility, the objective of this study was to determine the plant height, number of stems per m2, leaf length, number of leaves per stem and dry matter yield of triticale (X Triticum secale Wittmack), fertilized with compost (humus and humic acids) and urea. A complete randomized design was used with 6 treatments and 3 replications in experimental units of 60 m2 and seeding density of 100 kg of seed per ha. The treatments were: humus, humic acids, urea, humus + urea, humic acids + urea and control. The higher production indicate that the combination of organic and inorganic fertilizationwas better than the other treatments (p 0.05). The production of triticale in treatments with urea was up to 70% higher than the control and anothers treatments evaluated.El uso de abono es cada vez más frecuente en la agricultura por su efecto positivo sobre la fertilidad del suelo. El objetivo del presente estudio fue determinar la altura de planta, número de tallos por m2, longitud foliar, número de hojas por tallo y rendimiento de materia seca de triticale (X Triticum secale Wittmack), fertilizado con abono (humus de lombriz y ácidos húmicos) y urea. Los tratamientos fueron: humus de lombriz, ácidos húmicos, urea, humus de lombriz + urea, ácidos húmicos + urea y testigo. Se utilizó un diseño completo al azar, con 6 tratamientos y 3 repeticiones, en unidades experimentales de 60 m2 y densidad de siembra de 100 kg de semilla por ha. Los mayores resultados de producción indican que la combinación de la fertilización orgánica e inorgánica fue mejor que los demás tratamientos (p0,05). La producción de triticale en los tratamientos con urea fue hasta un 70% superior al testigo y a los tratamientos únicamente con abonos

Riesgos en las microfinanzas: una revisión y análisis bibliométrico

Las estrategias de recuperación en las microfinanzas no son las más acertadas. Algunas de las respuestas a estos desaciertos son los riesgos sociales. El tema se ha investigado por más de 25 años dejando muchos interrogantes hasta la actualidad. El objetivo de este artículo fue presentar una revisión bibliométrica y sistemática de los Riesgos en las Microfinanzas, con plataformas como Bibliometrix y Gephi. Se hicieron consultas en bases de datos como WoS y Scopus, que permitieron una clasificación de documentos en tres categorías según su trascendencia; clásicos, estructurales y recientes; adicional, se realiza un análisis de cocitaciones mostrando resultados en cuatro diferentes enfoques: Instituciones, Prevencion de VIH/SIDA, Crédito y Desarrollo de Género. Concluyendo el incumplimiento de los propósitos microfinancieros

Una nueva perspectiva del contagio financiero energético en Colombia: evidencia del análisis de ondas y dinámicas de comovimientos

Purpose: The aim of this study was to examine the existence of energy contagion from the most important energy indicators—oil, natural gas, and coal—to spot electricity prices in Colombia. Design/Methodology: The methodology employed here was correlational, with a quantitative approach. Daily data from February 2011 to December 2018 were used, excluding the 2008 financial crisis and the Covid-19 pandemic. The data were sourced from Refinitiv and XM. Wavelet analysis and co-movement dynamics were applied. Additionally, cross-correlation was used to analyze financial contagion from energy indicators to spot electricity prices. Findings: This study demonstrated that there are significant long-term correlations between energy indicators and spot electricity prices. It also determined the presence of energy contagion from natural gas and Brent crude oil to spot electricity prices during crisis periods. Regarding coal, there is no clear evidence of contagion. These findings are relevant for understanding how changes in the global energy market can affect electricity prices in the long term in an emerging economy like Colombia. Conclusions: Energy contagion impacts the global economy, especially in energy-dependent emerging markets. This study emphasizes the need to understand and mitigate risks in the energy market, offering key information to companies, investors, and policymakers. Originality: Advanced methods were employed here to analyze the impact of international fuel prices on the Colombian electricity market, identifying contagion periods and highlighting the vulnerability of emerging economies to changes in the global energy market.Objetivo: examinar la existencia de contagio financiero energético desde los principales indicadores de desempeño energético: petróleo, gas natural y carbón sobre los precios spot de energía en Colombia. Diseño/metodología: la metodología empleada en este estudio fue de tipo correlacional, con un enfoque cuantitativo. Se emplearon datos diarios de febrero de 2011 a diciembre de 2018, excluyendo la crisis financiera de 2008 y la pandemia por COVID-19. Los datos provienen de Refinitiv y XM. Se aplicó el análisis de ondas (wavelets analysis) y dinámica de comovimientos (co-movimientos dynamics). Además, se utilizó la correlación cruzada para el análisis de contagio financiero entre los indicadores de desempeño energético y los precios spot de energía. Resultados: la investigación demostró que existen correlaciones significativas a largo plazo entre los indicadores de desempeño energético y los precios spot de energía. Además, determinó la presencia de contagio del gas natural y del petróleo brent sobre los precios spot de energía durante periodos de crisis. Con respecto al carbón, no hay evidencia clara de contagio. Estos hallazgos son relevantes para comprender cómo los cambios en el mercado global de la energía pueden afectar los precios de esta a largo plazo en una economía emergente como la colombiana. Conclusiones: el contagio financiero energético impacta la economía global, especialmente en mercados emergentes dependientes de energía. Este estudio resalta la necesidad de comprender y mitigar riesgos en el mercado energético, ofreciendo información clave para empresas, inversores y formuladores de políticas. Originalidad: se emplearon métodos avanzados para analizar el impacto de los precios internacionales de combustibles en el mercado energético colombiano, identificando periodos de contagio y subrayando la vulnerabilidad de economías emergentes frente a cambios en el mercado global de la energía

A 3-biomarker 2-point-based risk stratification strategy in acute heart failure

[Abstract] Introduction and Objectives: Most multi-biomarker strategies in acute heart failure (HF) have only measured biomarkers in a single-point time. This study aimed to evaluate the prognostic yielding of NT-proBNP, hsTnT, Cys-C, hs-CRP, GDF15, and GAL-3 in HF patients both at admission and discharge. Methods: We included 830 patients enrolled consecutively in a prospective multicenter registry. Primary outcome was 12-month mortality. The gain in the C-index, calibration, net reclassification improvement (NRI), and integrated discrimination improvement (IDI) was calculated after adding each individual biomarker value or their combination on top of the best clinical model developed in this study (C-index 0.752, 0.715–0.789) and also on top of 4 currently used scores (MAGGIC, GWTG-HF, Redin-SCORE, BCN-bioHF). Results: After 12-month, death occurred in 154 (18.5%) cases. On top of the best clinical model, the addition of NT-proBNP, hs-CRP, and GDF-15 above the respective cutoff point at admission and discharge and their delta during compensation improved the C-index to 0.782 (0.747–0.817), IDI by 5% (p < 0.001), and NRI by 57% (p < 0.001) for 12-month mortality. A 4-risk grading categories for 12-month mortality (11.7, 19.2, 26.7, and 39.4%, respectively; p < 0.001) were obtained using combination of these biomarkers. Conclusion: A model including NT-proBNP, hs-CRP, and GDF-15 measured at admission and discharge afforded a mortality risk prediction greater than our clinical model and also better than the most currently used scores. In addition, this 3-biomarker panel defined 4-risk categories for 12-month mortality.Instituto de Salud Carlos III; RD06-0003-0000Instituto de Salud Carlos III; RD12/0042/000

Humaniora Investigación en humanidades 2022

Humaniora. Investigación en humanidades 2022 es resultado de investigación recoge la mayoría de las conferencias dictadas en la IV Jornada de Avances en Investigación. Facultad de Bellas Artes y Humanidades en el año 2022. El evento tuvo lugar en el día 8 de septiembre del año 2022. En ella, se dieron cita diferentes integrantes de los grupos de investigación de la facultad con sus respectivos proyectos que, o bien se encuentran ya en elaboración o bien se encuentran formulados para su elaboración en los años siguientes. Baste mencionar de manera muy general los grupos participantes: Estudios Culturales, Estudios políticos y Jurídicos, Filosofía y Educación, Filosofía AntiguaHumaniora. Humanities’ Research 2022 is the result of different research and includes the majority of the conferences given at the IV Conference about Advances’ Research. Faculty of Fine Arts and Humanities in the year 2022. The event took place on September 8, 2022. Different members of the Research Groups’ Faculty set place with their respective projects that either they are already in preparation or are formulated for production in the following years. Suffice it to mention in a very general way the participating groups: Cultural Studies, Political and Legal Studies, Philosophy and Education, Ancient PhilosophyCONTENIDO Presentación.......................................................................................................5 ARTE CAPÍTULO 1: Habitar el taller del artista para intuir un mundo de cosas........................... 11 FILOSOFÍA CAPÍTULO 2: Pasiones y política en Spinoza: democracia y libertad de pensamiento...............................................................................................31 CAPÍTULO 3: La relación entre temor y proaíresis en la ética aristotélica: una aproximación ...........................................................................................65 CAPÍTULO 4: Recuperación del pensamiento analógico de Aristóteles en un diálogo y dos tratados: Grilo, Tópicos y Retórica ................................83 CAPÍTULO 5: Importancia de la Relectura de la Política de Aristóteles para el Análisis de los Estados modernos......................................................105 ENSEÑANZA DE LA FILOSOFÍA CAPÍTULO 6: ¿Por qué es importante repensar la enseñanza de la filosofía?...........................13

A 3-Biomarker 2-Point-Based Risk Stratification Strategy in Acute Heart Failure

Altres ajuts: ISCIII/RD06-0003-0000Altres ajuts: ISCIII/RD12/0042/0002Introduction and Objectives: Most multi-biomarker strategies in acute heart failure (HF) have only measured biomarkers in a single-point time. This study aimed to evaluate the prognostic yielding of NT-proBNP, hsTnT, Cys-C, hs-CRP, GDF15, and GAL-3 in HF patients both at admission and discharge. Methods: We included 830 patients enrolled consecutively in a prospective multicenter registry. Primary outcome was 12-month mortality. The gain in the C-index, calibration, net reclassification improvement (NRI), and integrated discrimination improvement (IDI) was calculated after adding each individual biomarker value or their combination on top of the best clinical model developed in this study (C-index 0.752, 0.715-0.789) and also on top of 4 currently used scores (MAGGIC, GWTG-HF, Redin-SCORE, BCN-bioHF). Results: After 12-month, death occurred in 154 (18.5%) cases. On top of the best clinical model, the addition of NT-proBNP, hs-CRP, and GDF-15 above the respective cutoff point at admission and discharge and their delta during compensation improved the C-index to 0.782 (0.747-0.817), IDI by 5% (p < 0.001), and NRI by 57% (p < 0.001) for 12-month mortality. A 4-risk grading categories for 12-month mortality (11.7, 19.2, 26.7, and 39.4%, respectively; p < 0.001) were obtained using combination of these biomarkers. Conclusion: A model including NT-proBNP, hs-CRP, and GDF-15 measured at admission and discharge afforded a mortality risk prediction greater than our clinical model and also better than the most currently used scores. In addition, this 3-biomarker panel defined 4-risk categories for 12-month mortality

Staging Parkinson’s Disease According to the MNCD (Motor/Non-motor/Cognition/Dependency) Classification Correlates with Disease Severity and Quality of Life

Background: Recently, a novel simple classification called MNCD, based on 4 axes (Motor; Non-motor; Cognition; Dependency) and 5 stages, has been proposed to classify Parkinson's disease (PD). Objective: Our aim was to apply the MNCD classification in a cohort of PD patients for the first time and also to analyze the correlation with quality of life (QoL) and disease severity. Methods: Data from the baseline visit of PD patients recruited from 35 centers in Spain from the COPPADIS cohort from January 2016 to November 2017 were used to apply the MNCD classification. Three instruments were used to assess QoL: 1) the 39-item Parkinson's disease Questionnaire [PDQ-39]); PQ-10; the EUROHIS-QOL 8-item index (EUROHIS-QOL8). Results: Four hundred and thirty-nine PD patients (62.05 +/- 7.84 years old; 59% males) were included. MNCD stage was: stage 1, 8.4% (N = 37); stage 2, 62% (N = 272); stage 3, 28.2% (N = 124); stage 4-5, 1.4% (N = 6). A more advanced MNCD stage was associated with a higher score on the PDQ39SI (p < 0.0001) and a lower score on the PQ-10 (p < 0.0001) and EUROHIS-QOL8 (p < 0.0001). In many other aspects of the disease, such as disease duration, levodopa equivalent daily dose, motor symptoms, non-motor symptoms, and autonomy for activities of daily living, an association between the stage and severity was observed, with data indicating a progressive worsening related to disease progression throughout the proposed stages. Conclusion: Staging PD according to the MNCD classification correlated with QoL and disease severity. The MNCD could be a proper tool to monitor the progression of PD

Sleep Problems Are Related to a Worse Quality of Life and a Greater Non-Motor Symptoms Burden in Parkinson’s Disease

COPPADIS Study Group.[Introduction] The aim of the present study was to examine the frequency of self-reported sleep problems and their associated factors in a large cohort of PD patients.[Methods] PD patients and controls, recruited from 35 centers of Spain from the COPPADIS cohort were included in this cross-sectional study. Sleep problems were assessed by the Spanish version of the Parkinson’s disease Sleep Scale version 1 (PDSS-1). An overall score below 82 or a score below 5 on at least 1 item was defined as sleep problems.[Results] The frequency of sleep problems was nearly double in PD patients compared to controls: 65.8% (448/681) vs 33.5% (65/206) (p < 0.0001). Mean total PDSS score was lower in PD patients than controls: 114.9 ± 28.8 vs 132.8 ± 16.3 (p < 0.0001). Quality of life (QoL) was worse in PD patients with sleep problems compared to those without: PDQ-39SI, 19.3 ± 14 vs 13 ± 11.6 (p < 0.0001); EUROHIS-QoL8, 3.7 ± 0.5 vs 3.9 ± 0.5 (p < 0.0001). Non-motor symptoms burden (NMSS; OR = 1.029; 95%CI 1.015–1.043; p < 0.0001) and impulse control behaviors (QUIP-RS; OR = 1.054; 95%CI 1.009–1.101; p = 0.018) were associated with sleep problems after adjustment for age, gender, disease duration, daily equivalent levodopa dose, H&Y, UPDRS-III, UPDRS-IV, PD-CRS, BDI-II, NPI, VAS-Pain, VAFS, FOGQ, and total number of non-antiparkinsonian treatments.[Conclusion] Sleep problems were frequent in PD patients and were related to both a worse QoL and a greater non-motor symptoms burden in PD. These findings call for increased awareness of sleep problems in PD patients.Peer reviewe

Predictors of Global Non-Motor Symptoms Burden Progression in Parkinson’s Disease. Results from the COPPADIS Cohort at 2-Year Follow-Up

Background and Objective: Non-motor symptoms (NMS) progress in different ways between Parkinson's disease (PD) patients. The aim of the present study was to (1) analyze the change in global NMS burden in a PD cohort after a 2-year follow-up, (2) to compare the changes with a control group, and (3) to identify predictors of global NMS burden progression in the PD group. Material and Methods: PD patients and controls, recruited from 35 centers of Spain from the COPPADIS cohort from January 2016 to November 2017, were followed-up with after 2 years. The Non-Motor Symptoms Scale (NMSS) was administered at baseline (V0) and at 24 months ± 1 month (V2). Linear regression models were used for determining predictive factors of global NMS burden progression (NMSS total score change from V0 to V2 as dependent variable). Results: After the 2-year follow-up, the mean NMS burden (NMSS total score) significantly increased in PD patients by 18.8% (from 45.08 ± 37.62 to 53.55 ± 42.28; p < 0.0001; N = 501; 60.2% males, mean age 62.59 ± 8.91) compared to no change observed in controls (from 14.74 ± 18.72 to 14.65 ± 21.82; p = 0.428; N = 122; 49.5% males, mean age 60.99 ± 8.32) (p < 0.0001). NMSS total score at baseline (β = -0.52), change from V0 to V2 in PDSS (Parkinson's Disease Sleep Scale) (β = -0.34), and change from V0 to V2 in NPI (Neuropsychiatric Inventory) (β = 0.25) provided the highest contributions to the model (adjusted R-squared 0.41; Durbin-Watson test = 1.865). Conclusions: Global NMS burden demonstrates short-term progression in PD patients but not in controls and identifies worsening sleep problems and neuropsychiatric symptoms as significant independent predictors of this NMS progression