192 research outputs found
Integration of biologicals and value added nano-materials in seed treatment: aiming for sustainable agriculture / by Rita Choudhary
In order to contribute to the sustainable agricultural systems; the work carried out in this thesis encompasses developing a novel formulation and strategies for seed coating. Optimization and validations of a formulation having various vital components such as biologicals, polymers, fungicides, and nano-nutrients, which may help in building better practices towards sustainable agriculture.<br /
An observational study on assessment of Sara in Madhumeha (Diabetes Mellitus) patients
Background: Sara one of the factor of Dashvidha Pariksha, is the excellent or best functional aspect of Dhatu responsible for rendering strength to a person. Madhumeha is a morbid condition in which vitiation of Kapha Dosha and Meda Dhatu is the major factor of this disease. In this disease almost all Dhatu get vitiated along with Oja, due to which the condition of patient afflicted with Madhumeha goes on deteriorating and leads to serious consequences in form of complications. Aim and Objectives: a) To assess the Sara condition in the patients of Madhumeha. b) To assess the Atura Bala on the basis of Sara Pariksha. c) Study of complications in Madhumeha patients. Materials and Methods: The present study is a cross sectional observational study, which has been conducted in 100 patients of Madhumeha under Stratum A and Stratum B with the help of proforma in the form of validated questionnaire. Results: Maximum 80.56% patients were having Avara Medasara in Stratum A and 85.94% patients in Stratum B were having Avara Shukrasara. On overall assessment, Madhyam Sara and Avara Sara was found in maximum patients of Stratum A and B respectively
Citrobacter rodentium is an unstable pathogen showing evidence of significant genomic flux.
Citrobacter rodentium is a natural mouse pathogen that causes attaching and effacing (A/E) lesions. It shares a common virulence strategy with the clinically significant human A/E pathogens enteropathogenic E. coli (EPEC) and enterohaemorrhagic E. coli (EHEC) and is widely used to model this route of pathogenesis. We previously reported the complete genome sequence of C. rodentium ICC168, where we found that the genome displayed many characteristics of a newly evolved pathogen. In this study, through PFGE, sequencing of isolates showing variation, whole genome transcriptome analysis and examination of the mobile genetic elements, we found that, consistent with our previous hypothesis, the genome of C. rodentium is unstable as a result of repeat-mediated, large-scale genome recombination and because of active transposition of mobile genetic elements such as the prophages. We sequenced an additional C. rodentium strain, EX-33, to reveal that the reference strain ICC168 is representative of the species and that most of the inactivating mutations were common to both isolates and likely to have occurred early on in the evolution of this pathogen. We draw parallels with the evolution of other bacterial pathogens and conclude that C. rodentium is a recently evolved pathogen that may have emerged alongside the development of inbred mice as a model for human disease
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CALTRANS: Impact of the Use of Portland-Limestone Cement on Concrete Performance as Plain or Reinforced Material - Final Report
CALTRANS does not currently allow Portland-Limestone Cements (PLC) to replace Ordinary Portland Cement (OPC) in concrete. PLC has been proposed for consideration in CALTRANS specifications due to potential benefits in reducing greenhouse gas (GHG) emissions. This report outlines a comprehensive plan to provide both experimental and computational analysis results to address whether PLC may replace OPC without loss of mechanical and durability performance of concrete materials and mixtures specific to California. The objective of this study was to provide data for CALTRANS to make informed decisions on whether specification changes to permit use of PLC would be appropriate. Additionally, the research team was asked to assess the impact of added limestone (LS) powder as an alternative to using ASTM C 595/AASHTO M 240 cement
Biological Insights into the Expression of Translation Initiation Factors from Recombinant CHOK1SV Cell Lines and their Relationship to Enhanced Productivity
Translation initiation is on the critical pathway for the production of monoclonal antibodies (mAb) by mammalian cells. Formation of a closed loop structure comprised of mRNA, a number of eukaryotic initiation factors and ribosomal proteins has been proposed to aid re-initiation of translation and therefore increase global translational efficiency. We have determined mRNA and protein levels of the key components of the closed loop; eukaryotic initiation factors (eIF3a, eIF3b, eIF3c, eIF3h, eIF3i and eIF4G1), poly(A) binding protein (PABP) 1 and PABP interacting protein 1 (PAIP1) across a panel of 30 recombinant mAb-producing GS-CHOK1SV cell lines with a broad range of growth characteristics and production levels of a model recombinant mAb. We have used a multi-level statistical approach to investigate the relationship between key performance indicators (cell growth and recombinant antibody productivity) and the intracellular amounts of target translation initiation factor proteins and the mRNAs encoding them. We show that high-producing cell lines maintain amounts of the translation initiation factors involved in the formation of the closed loop mRNA, maintaining these proteins at appropriate levels to deliver enhanced recombinant protein production. We then utilise knowledge of the amounts of these factors to build predictive models for, and use cluster analysis to identify, high-producing cell lines. This study therefore defines the translation initiation factor amounts that are associated with highly productive recombinant GS-CHOK1SV cell lines that may be targets for screening highly productive cell lines or to engineer new host cell lines with the potential for enhanced recombinant antibody productivity
Combined Forward-Backward Asymmetry Measurements in Top-Antitop Quark Production at the Tevatron
The CDF and D0 experiments at the Fermilab Tevatron have measured the asymmetry between yields of forward- and backward-produced top and antitop quarks based on their rapidity difference and the asymmetry between their decay leptons. These measurements use the full data sets collected in proton-antiproton collisions at a center-of-mass energy of TeV. We report the results of combinations of the inclusive asymmetries and their differential dependencies on relevant kinematic quantities. The combined inclusive asymmetry is . The combined inclusive and differential asymmetries are consistent with recent standard model predictions
Infected pancreatic necrosis: outcomes and clinical predictors of mortality. A post hoc analysis of the MANCTRA-1 international study
: The identification of high-risk patients in the early stages of infected pancreatic necrosis (IPN) is critical, because it could help the clinicians to adopt more effective management strategies. We conducted a post hoc analysis of the MANCTRA-1 international study to assess the association between clinical risk factors and mortality among adult patients with IPN. Univariable and multivariable logistic regression models were used to identify prognostic factors of mortality. We identified 247 consecutive patients with IPN hospitalised between January 2019 and December 2020. History of uncontrolled arterial hypertension (p = 0.032; 95% CI 1.135-15.882; aOR 4.245), qSOFA (p = 0.005; 95% CI 1.359-5.879; aOR 2.828), renal failure (p = 0.022; 95% CI 1.138-5.442; aOR 2.489), and haemodynamic failure (p = 0.018; 95% CI 1.184-5.978; aOR 2.661), were identified as independent predictors of mortality in IPN patients. Cholangitis (p = 0.003; 95% CI 1.598-9.930; aOR 3.983), abdominal compartment syndrome (p = 0.032; 95% CI 1.090-6.967; aOR 2.735), and gastrointestinal/intra-abdominal bleeding (p = 0.009; 95% CI 1.286-5.712; aOR 2.710) were independently associated with the risk of mortality. Upfront open surgical necrosectomy was strongly associated with the risk of mortality (p < 0.001; 95% CI 1.912-7.442; aOR 3.772), whereas endoscopic drainage of pancreatic necrosis (p = 0.018; 95% CI 0.138-0.834; aOR 0.339) and enteral nutrition (p = 0.003; 95% CI 0.143-0.716; aOR 0.320) were found as protective factors. Organ failure, acute cholangitis, and upfront open surgical necrosectomy were the most significant predictors of mortality. Our study confirmed that, even in a subgroup of particularly ill patients such as those with IPN, upfront open surgery should be avoided as much as possible. Study protocol registered in ClinicalTrials.Gov (I.D. Number NCT04747990)
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Research and Design of a Routing Protocol in Large-Scale Wireless Sensor Networks
无线传感器网络,作为全球未来十大技术之一,集成了传感器技术、嵌入式计算技术、分布式信息处理和自组织网技术,可实时感知、采集、处理、传输网络分布区域内的各种信息数据,在军事国防、生物医疗、环境监测、抢险救灾、防恐反恐、危险区域远程控制等领域具有十分广阔的应用前景。 本文研究分析了无线传感器网络的已有路由协议,并针对大规模的无线传感器网络设计了一种树状路由协议,它根据节点地址信息来形成路由,从而简化了复杂繁冗的路由表查找和维护,节省了不必要的开销,提高了路由效率,实现了快速有效的数据传输。 为支持此路由协议本文提出了一种自适应动态地址分配算——ADAR(AdaptiveDynamicAddre...As one of the ten high technologies in the future, wireless sensor network, which is the integration of micro-sensors, embedded computing, modern network and Ad Hoc technologies, can apperceive, collect, process and transmit various information data within the region. It can be used in military defense, biomedical, environmental monitoring, disaster relief, counter-terrorism, remote control of haz...学位:工学硕士院系专业:信息科学与技术学院通信工程系_通信与信息系统学号:2332007115216
En framtida placering i Kinafond eller USA-fond? : Ett säkrare val för investeraren
To invest money in funds is increasing rapidly in popularity and one of the biggest reasons is that banks are offering a greater range of funds. Information about funds is always easy to find and it is easy to invest money in a fund because the bank takes care of all the management of the fund. The essay examines two funds from two different countries with an aim to choose the one with best potential yield. The first fund is entirely invested in North America and the second fund invests in Asia, with most of its possessions in companies from China. Both these funds invest in wellknown companies in respective region. The essay is limited to compare these funds with data from 2005 to 2009. Information was collected from Morningstar and Avanza Bank for the quantitative examination. The qualitative examination was based on an interview with a fund analyzer. The financial instruments were used to compare the funds and choose the fund that had the highest yield in relation to risk. This fund was also the one chosen as the better of the two. In addition evaluation was done by calculation of financial variables, the standard deviation, total return, average return, Sharpe ratio and a comparison of the funds yields with yields from similar funds in the same region. Result shows high yields from the fund invested in China, compared to the much lower yields for the North American fund. The China fund had a standard deviation (risk) of 46, 1 % while the North American fund had 23, 9 %. This is because the yields of the China fund were much more variably. In addition the yields were also much higher for the China fund. The holding period return was calculated to a positive result for the China fund while the North American fund showed a negative result. Also the average yield shows a positive result for the China fund and a negative result for the North American fund. The Sharpe ratio that measures the yield with regards to the risk shows a better result for the China fund. In comparison with similar funds in the same regions the China fund has given higher yields than the average fund in the same region, while the North American fund gave less yields than the average fund that invests in the same region. The fund analyzer was more positive to the China fund, due to its appeal to the investor
Not Available
Not AvailableAdoption of drip irrigation method offers opportunity for efficient use of water and
higher economic yield of cotton under irrigated conditions in arid and semi-arid regions. A
field experiment was carried out at the Soil Research Farm of Chaudhary Charan Singh
Haryana Agricultural University, Hisar during 2014 for evaluating the different methods
of irrigation for enhancing water use efficiency in cotton. The experiment was consisted of
three methods of irrigation (drip, furrow and flood irrigation) and four cultivars of cotton
viz., Bt (MRC-7017), Bt (RCH-134), American (H-1236) and Desi (HD-123). The results
indicated that drip irrigation significantly increased plant height, number of bolls per
plant, boll weight, and number of monopods and sympods per plant. The application of
irrigation with drip and furrow methods resulted in increase in seed cotton yield over flood
method. The seed cotton yield was recorded highest of 2671 kg/ha of American (H-1236)
followed by 2510 kg/ha of Bt (MRC-7017), 2287 kg/ha of Desi (HD-123) and 2151 kg/ha
of Bt (RCH-134) in drip irrigation. The water use efficiency (WUE) was found highest in
drip irrigation as compared to other methods in all the four cotton cultivars. The highest
WUE of 0.58 kg/m3 was found in American (H-1236), followed by Bt (MRC-7017), Desi
(HD-123) and lowest in Bt (RCH-134). The results conclude that drip irrigation has potential
to increase the seed cotton yield and water use efficiency in arid and semi-arid region of
the state.Not Availabl
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