390 research outputs found
Forced Stratified Turbulence: Successive Transitions with Reynolds Number
Numerical simulations are made for forced turbulence at a sequence of
increasing values of Reynolds number, R, keeping fixed a strongly stable,
volume-mean density stratification. At smaller values of R, the turbulent
velocity is mainly horizontal, and the momentum balance is approximately
cyclostrophic and hydrostatic. This is a regime dominated by so-called pancake
vortices, with only a weak excitation of internal gravity waves and large
values of the local Richardson number, Ri, everywhere. At higher values of R
there are successive transitions to (a) overturning motions with local
reversals in the density stratification and small or negative values of Ri; (b)
growth of a horizontally uniform vertical shear flow component; and (c) growth
of a large-scale vertical flow component. Throughout these transitions, pancake
vortices continue to dominate the large-scale part of the turbulence, and the
gravity wave component remains weak except at small scales.Comment: 8 pages, 5 figures (submitted to Phys. Rev. E
The price of rapid exit in venture capital-backed IPOs
This paper proposes an explanation for two empirical puzzles surrounding initial public offerings (IPOs). Firstly, it is well documented that IPO underpricing increases during “hot issue” periods. Secondly, venture capital (VC) backed IPOs are less underpriced than non-venture capital backed IPOs during normal periods of activity, but the reverse is true during hot issue periods: VC backed IPOs are more underpriced than non-VC backed ones. This paper shows that when IPOs are driven by the initial investor’s desire to exit from an existing investment in order to finance a new venture, both the value of the new venture and the value of the existing firm to be sold in the IPO drive the investor’s choice of price and fraction of shares sold in the IPO. When this is the case, the availability of attractive new ventures increases equilibrium underpricing, which is what we observe during hot issue periods. Moreover, I show that underpricing is affected by the severity of the moral hazard problem between an investor and the firm’s manager. In the presence of a moral hazard problem the degree of equilibrium underpricing is more sensitive to changes in the value of the new venture. This can explain why venture capitalists, who often finance firms with more severe moral hazard problems, underprice IPOs less in normal periods, but underprice more strongly during hot issue periods. Further empirical implications relating the fraction of shares sold and the degree of underpricing are presented
A Helicity-Based Method to Infer the CME Magnetic Field Magnitude in Sun and Geospace: Generalization and Extension to Sun-Like and M-Dwarf Stars and Implications for Exoplanet Habitability
Patsourakos et al. (Astrophys. J. 817, 14, 2016) and Patsourakos and
Georgoulis (Astron. Astrophys. 595, A121, 2016) introduced a method to infer
the axial magnetic field in flux-rope coronal mass ejections (CMEs) in the
solar corona and farther away in the interplanetary medium. The method, based
on the conservation principle of magnetic helicity, uses the relative magnetic
helicity of the solar source region as input estimates, along with the radius
and length of the corresponding CME flux rope. The method was initially applied
to cylindrical force-free flux ropes, with encouraging results. We hereby
extend our framework along two distinct lines. First, we generalize our
formalism to several possible flux-rope configurations (linear and nonlinear
force-free, non-force-free, spheromak, and torus) to investigate the dependence
of the resulting CME axial magnetic field on input parameters and the employed
flux-rope configuration. Second, we generalize our framework to both Sun-like
and active M-dwarf stars hosting superflares. In a qualitative sense, we find
that Earth may not experience severe atmosphere-eroding magnetospheric
compression even for eruptive solar superflares with energies ~ 10^4 times
higher than those of the largest Geostationary Operational Environmental
Satellite (GOES) X-class flares currently observed. In addition, the two
recently discovered exoplanets with the highest Earth-similarity index, Kepler
438b and Proxima b, seem to lie in the prohibitive zone of atmospheric erosion
due to interplanetary CMEs (ICMEs), except when they possess planetary magnetic
fields that are much higher than that of Earth.Comment: http://adsabs.harvard.edu/abs/2017SoPh..292...89
The selection of comparators for randomized controlled trials of health-related behavioral interventions: recommendations of an NIH expert panel
Objectives: To provide recommendations for the selection of comparators for randomized controlled trials of health-related behavioral interventions. Study Design and Setting: The National Institutes of Health Office of Behavioral and Social Science Research convened an expert panel to critically review the literature on control or comparison groups for behavioral trials and to develop strategies for improving comparator choices and for resolving controversies and disagreements about comparators. Results: The panel developed a Pragmatic Model for Comparator Selection in Health-Related Behavioral Trials. The model indicates that the optimal comparator is the one that best serves the primary purpose of the trial but that the optimal comparator's limitations and barriers to its use must also be taken into account. Conclusion: We developed best practice recommendations for the selection of comparators for health-related behavioral trials. Use of the Pragmatic Model for Comparator Selection in Health-Related Behavioral Trials can improve the comparator selection process and help resolve disagreements about comparator choices
Single Spin Asymmetry in Polarized Proton-Proton Elastic Scattering at GeV
We report a high precision measurement of the transverse single spin
asymmetry at the center of mass energy GeV in elastic
proton-proton scattering by the STAR experiment at RHIC. The was measured
in the four-momentum transfer squared range \GeVcSq, the region of a significant interference between the
electromagnetic and hadronic scattering amplitudes. The measured values of
and its -dependence are consistent with a vanishing hadronic spin-flip
amplitude, thus providing strong constraints on the ratio of the single
spin-flip to the non-flip amplitudes. Since the hadronic amplitude is dominated
by the Pomeron amplitude at this , we conclude that this measurement
addresses the question about the presence of a hadronic spin flip due to the
Pomeron exchange in polarized proton-proton elastic scattering.Comment: 12 pages, 6 figure
Functional and genetic analysis of regulatory regions of coliphage H-19B: location of shiga-like toxin and lysis genes suggest a role for phage functions in toxin release
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/74784/1/j.1365-2958.1998.00890.x.pd
Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: A pooled analysis of 1018 population-based measurement studies with 88.6 million participants
Background: Change in the prevalence of raised blood pressure could be due to both shifts in the entire distribution of blood pressure (representing the combined effects of public health interventions and secular trends) and changes in its high-blood-pressure tail (representing successful clinical interventions to control blood pressure in the hypertensive population). Our aim was to quantify the contributions of these two phenomena to the worldwide trends in the prevalence of raised blood pressure. Methods: We pooled 1018 population-based studies with blood pressure measurements on 88.6 million participants from 1985 to 2016. We first calculated mean systolic blood pressure (SBP), mean diastolic blood pressure (DBP) and prevalence of raised blood pressure by sex and 10-year age group from 20–29 years to 70–79 years in each study, taking into account complex survey design and survey sample weights, where relevant. We used a linear mixed effect model to quantify the association between (probit-transformed) prevalence of raised blood pressure and age-group- and sex-specific mean blood pressure. We calculated the contributions of change in mean SBP and DBP, and of change in the prevalence-mean association, to the change in prevalence of raised blood pressure. Results: In 2005–16, at the same level of population mean SBP and DBP, men and women in South Asia and in Central Asia, the Middle East and North Africa would have the highest prevalence of raised blood pressure, and men and women in the high-income Asia Pacific and high-income Western regions would have the lowest. In most region-sex-age groups where the prevalence of raised blood pressure declined, one half or more of the decline was due to the decline in mean blood pressure. Where prevalence of raised blood pressure has increased, the change was entirely driven by increasing mean blood pressure, offset partly by the change in the prevalence-mean association. Conclusions: Change in mean blood pressure is the main driver of the worldwide change in the prevalence of raised blood pressure, but change in the high-blood-pressure tail of the distribution has also contributed to the change in prevalence, especially in older age groups.Bin Zhou, James Bentham, Mariachiara Di Cesare … Robert J Adams … Tiffany K Gill … Anne W Taylor … et al. NCD Risk Factor Collaboration (NCD-RisC
Small-scale spatial variability of selected soil biological properties
A strategy for sampling soil from intact monolith lysimeters was established based on measurements of spatial heterogeneity within the lysimeter area. This was part of an ongoing study to determine relationships between soil microbial diversity and nutrient loss by leaching. The sampling protocol had to allow for collection of soil on a regular basis (as opposed to destructive sampling) and ensure high spatial independence of subsamples. On each of two sites (one developed under organic crop management, the other under conventional crop management), ten 15-cm soil cores (sampling points) were taken from three areas (replicates) of 50-cm-diameter (lysimeter surface area) and separately analysed for biotic (microbial biomass carbon and nitrogen; arginine deaminase activity) and abiotic (total carbon and nitrogen) soil properties. The data was tested for variability, expressed as coefficient of variance (biotic and abiotic), and spatial heterogeneity using geostatistics (biotic properties). The biotic soil properties showed significant differences among sampling points, whereas the abiotic parameters were useful in differentiating on a larger scale, i.e. between sites. For all soil properties tested, the differences among the replicates were smaller than those between sites or among points indicating that, in the main experiment, all treatments can be sampled following the same pattern.Geostatistical analysis and fitting of an exponential model showed that a spatial structure exists in the biotic soil properties and that the samples are independent beyond separation distances of 25-30 cm. A revised sampling pattern consisting of 11 samples per lysimeter is described
Transitions of cardio-metabolic risk factors in the Americas between 1980 and 2014
Describing the prevalence and trends of cardiometabolic risk factors that are associated with non-communicable diseases (NCDs) is crucial for monitoring progress, planning prevention, and providing evidence to support policy efforts. We aimed to analyse the transition in body-mass index (BMI), obesity, blood pressure, raised blood pressure, and diabetes in the Americas, between 1980 and 2014
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