9 research outputs found

    Communicating simply, but not too simply: Reporting of participants and speech and language interventions for aphasia after stroke

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    Purpose: Speech and language pathology (SLP) for aphasia is a complex intervention delivered to a heterogeneous population within diverse settings. Simplistic descriptions of participants and interventions in research hinder replication, interpretation of results, guideline and research developments through secondary data analyses. This study aimed to describe the availability of participant and intervention descriptors in existing aphasia research datasets. Method: We systematically identified aphasia research datasets containing ≥10 participants with information on time since stroke and language ability. We extracted participant and SLP intervention descriptions and considered the availability of data compared to historical and current reporting standards. We developed an extension to the Template for Intervention Description and Replication checklist to support meaningful classification and synthesis of the SLP interventions to support secondary data analysis. Result: Of 11, 314 identified records we screened 1131 full texts and received 75 dataset contributions. We extracted data from 99 additional public domain datasets. Participant age (97.1%) and sex (90.8%) were commonly available. Prior stroke (25.8%), living context (12.1%) and socio-economic status (2.3%) were rarely available. Therapy impairment target, frequency and duration were most commonly available but predominately described at group level. Home practice (46.3%) and tailoring (functional relevance 46.3%) were inconsistently available. Conclusion : Gaps in the availability of participant and intervention details were significant, hampering clinical implementation of evidence into practice and development of our field of research. Improvements in the quality and consistency of participant and intervention data reported in aphasia research are required to maximise clinical implementation, replication in research and the generation of insights from secondary data analysis. Systematic review registration: PROSPERO CRD4201811094

    Communicating simply, but not too simply : Reporting of participants and speech and language interventions for aphasia after stroke

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    Purpose:Speech and language pathology (SLP) for aphasia is a complex intervention delivered to a heterogeneous population within diverse settings. Simplistic descriptions of participants and interventions in research hinder replication, interpretation of results, guideline and research developments through secondary data analyses. This study aimed to describe the availability of participant and intervention descriptors in existing aphasia research datasets. Method:We systematically identified aphasia research datasets containing >= 10 participants with information on time since stroke and language ability. We extracted participant and SLP intervention descriptions and considered the availability of data compared to historical and current reporting standards. We developed an extension to the Template for Intervention Description and Replication checklist to support meaningful classification and synthesis of the SLP interventions to support secondary data analysis. Result:Of 11, 314 identified records we screened 1131 full texts and received 75 dataset contributions. We extracted data from 99 additional public domain datasets. Participant age (97.1%) and sex (90.8%) were commonly available. Prior stroke (25.8%), living context (12.1%) and socio-economic status (2.3%) were rarely available. Therapy impairment target, frequency and duration were most commonly available but predominately described at group level. Home practice (46.3%) and tailoring (functional relevance 46.3%) were inconsistently available. Conclusion :Gaps in the availability of participant and intervention details were significant, hampering clinical implementation of evidence into practice and development of our field of research. Improvements in the quality and consistency of participant and intervention data reported in aphasia research are required to maximise clinical implementation, replication in research and the generation of insights from secondary data analysis. Systematic review registration:PROSPERO CRD42018110947publishedVersionPeer reviewe

    A JWST inventory of protoplanetary disk ices. The edge-on protoplanetary disk HH 48 NE, seen with the Ice Age ERS program

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    <p>JWST NIRSpec G395H spectrum for HH 48 NE edge-on disk, as analyzed in Sturm et al. (2023). DOI: 10.1051/0004-6361/202347512</p&gt

    Inflammatory mechanisms in diabetic kidney disease

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    Tests of Lorentz invariance: a 2013 update

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    We present an updated review of Lorentz invariance tests in effective field theories (EFTs) in the matter as well as in the gravity sector. After a general discussion of the role of Lorentz invariance and a derivation of its transformations along the so-called von Ignatovski theorem, we present the dynamical frameworks developed within local EFT and the available constraints on the parameters governing the Lorentz breaking effects. In the end, we discuss two specific examples: the OPERA 'affaire' and the case of Ho\u159ava- Lifshitz gravity. The first case will serve as an example, and a caveat, of the practical application of the general techniques developed for constraining Lorentz invariance violation to a direct observation potentially showing these effects. The second case will show how the application of the same techniques to a specific quantum gravity scenario has far-reaching implications not foreseeable in a purely phenomenological EFT approach
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