Pion Cloud Contribution to K+ Nucleus Scattering

A careful reanalysis is done of the contribution to $K^{+}$ nucleus scattering from the interaction of the kaon with the virtual pion cloud. The usual approximations made in the evaluation of the related kaon selfenergy are shown to fail badly. We also find new interaction mechanisms which provide appreciable corrections to the kaon selfenergy. Some of these contribute to the imaginary part below pion creation threshold. The inclusion of these new mechanisms in the inelastic part of the optical potential produces a significant improvement in the differential and total $K^{+}$ nuclear cross sections. Uncertainties remain in the dispersive part of the optical potential.Comment: 27 pages, 17 figures (not all of them included, please request them), report UG-DFM-2/9

Coherent pion production in neutrino nucleus collision in the 1 GeV region

We calculate cross sections for coherent pion production in nuclei induced by neutrinos and antineutrinos of the electron and muon type. The analogies and differences between this process and the related ones of coherent pion production induced by photons, or the (p,n) and $(^3 He, t)$ reactions are discussed. The process is one of the several ones occurring for intermediate energy neutrinos, to be considered when detecting atmospheric neutrinos. For this purpose the results shown here can be easily extrapolated to other energies and other nuclei.Comment: 13 pages, LaTex, 8 post-script figures available at [email protected]

Mesonic and Binding Contributions to the EMC Effect in a Relativistic Many Body Approach

We revise the conventional nuclear effects of Fermi motion, binding and pionic effects in deep inelastic lepton scattering using a relativistic formalism for an interacting Fermi sea and the local density approximation to translate results from nuclear matter to finite nuclei. In addition we also consider effects from rho-meson renormalization in the nucleus. The use of nucleon Green's functions in terms of their spectral functions offers a precise way to account for Fermi motion and binding. On the other hand the use of many body Feynman diagrams in a relativistic framework allows one to avoid using prescriptions given in the past to introduce relativistic corrections in a non relativistic formalism. We show that with realistic nucleon spectral functions and meson nucleus selfenergies one can get a reasonable description of the EMC effect for x > 0.15, outside the shadowing region.Comment: 31 pages, LaTeX, 11 PostScript figures, final version to appear in Nuclear Physics

Resistencia a la insulina y Enfermedad de Alzheimer prodrómica en la Comunidad de La Rioja: primeras impresiones

Trabajo presentado en la XLIII Reunión de la Sociedad de Neurología del País Vasco, celebrada en Vitoria (España), el 6 de mayo de 202

Mice Lacking Endoglin in Macrophages Show an Impaired Immune Response

Endoglin is an auxiliary receptor for members of the TGF-β superfamily and plays an important role in the homeostasis of the vessel wall. Mutations in endoglin gene (ENG) or in the closely related TGF-β receptor type I ACVRL1/ALK1 are responsible for a rare dominant vascular dysplasia, the Hereditary Hemorrhagic Telangiectasia (HHT), or Rendu-Osler-Weber syndrome. Endoglin is also expressed in human macrophages, but its role in macrophage function remains unknown. In this work, we show that endoglin expression is triggered during the monocyte-macrophage differentiation process, both in vitro and during the in vivo differentiation of blood monocytes recruited to foci of inflammation in wild-type C57BL/6 mice. To analyze the role of endoglin in macrophages in vivo, an endoglin myeloid lineage specific knock-out mouse line (Engfl/flLysMCre) was generated. These mice show a predisposition to develop spontaneous infections by opportunistic bacteria. Engfl/flLysMCre mice also display increased survival following LPS-induced peritonitis, suggesting a delayed immune response. Phagocytic activity is impaired in peritoneal macrophages, altering one of the main functions of macrophages which contributes to the initiation of the immune response. We also observed altered expression of TGF-β1 target genes in endoglin deficient peritoneal macrophages. Overall, the altered immune activity of endoglin deficient macrophages could help to explain the higher rate of infectious diseases seen in HHT1 patientsThis work was funded by: Ministerio de Economía y Competitividad of Spain (SAF2011- 23475 to LMB; SAF2013-43421-R and SAF2010-19222 to CB; and Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), and FEDER funds. CIBERER is an initiative of the Instituto de Salud Carlos III (ISCIII) of SPAIN supported by FEDER fund

Delta excitation in K^+-nucleus collisions

We present calculations for \Delta excitation in the (K^+,K^+) reaction in nuclei. The background from quasielastic K^+ scattering in the \Delta region is also evaluated and shown to be quite small in some kinematical regions, so as to allow for a clean identification of the \Delta excitation strength. Nuclear effects tied to the \Delta renormalization in the nucleus are considered and the reaction is shown to provide new elements to enrich our knowledge of the \Delta properties in a nuclear medium.Comment: 11 pages, 6 figures, LaTe

Estudio descriptivo del patrón de dieta y adherencia a la Dieta Mediterránea en pacientes con Enfermedad de Alzheimer prodrómica en La Rioja

Trabajo presentado en la Reunión Anual de la Sociedad de Neurología del País Vasco, celebrada en San Sebastián (España), los días 3 y 4 de marzo de 202