80 research outputs found

    A methodology for systematic mapping in environmental sciences

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    Systematic mapping was developed in social sciences in response to a lack of empirical data when answering questions using systematic review methods, and a need for a method to describe the literature across a broad subject of interest. Systematic mapping does not attempt to answer a specific question as do systematic reviews, but instead collates, describes and catalogues available evidence (e.g. primary, secondary, theoretical, economic) relating to a topic or question of interest. The included studies can be used to identify evidence for policy-relevant questions, knowledge gaps (to help direct future primary research) and knowledge clusters (sub-sets of evidence that may be suitable for secondary research, for example systematic review). Evidence synthesis in environmental sciences faces similar challenges to those found in social sciences. Here we describe the translation of systematic mapping methodology from social sciences for use in environmental sciences. We provide the first process-based methodology for systematic maps, describing the stages involved: establishing the review team and engaging stakeholders; setting the scope and question; setting inclusion criteria for studies; scoping stage; protocol development and publication; searching for evidence; screening evidence; coding; production of a systematic map database; critical appraisal (optional); describing and visualising the findings; report production and supporting information. We discuss the similarities and differences in methodology between systematic review and systematic mapping and provide guidance for those choosing which type of synthesis is most suitable for their requirements. Furthermore, we discuss the merits and uses of systematic mapping and make recommendations for improving this evolving methodology in environmental sciences

    Evidence for the effects of neonicotinoids used in arable crop production on non-target organisms and concentrations of residues in relevant matrices: a systematic map protocol

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    Background Neonicotinoid insecticides (NNIs) have been routinely used in arable crop protection since their development in the early 1990s. These insecticides have been subject to the same registration procedures as other groups of pesticides, thus meet the same environmental hazard standards as all crop protection products. However, during the last 10 years the debate regarding their possible detrimental impact on non-target organisms, particularly pollinators, has become increasingly contentious and widely debated. Against this background, legislators and politicians in some countries, have been faced with a need to make decisions on the future registration of some or all of this class of insecticides, based on published evidence that in some areas is incomplete or limited in extent. This has created much concern in agricultural communities that consider that the withdrawal of these insecticides is likely to have significant negative economic, socio-economic and environmental consequences. Methods The proposed systematic map aims to address the following primary question: What is the available evidence for the effects of neonicotinoids used in arable crop production on non-target organisms and concentrations of residues in relevant matrices? The primary question will be divided into two sub-questions to gather research literature for (1) the effect of NNIs on non-target organisms (2) the occurrence of concentrations of NNIs in matrices of relevance to non-target organisms (i.e. exposure routes). The systematic map will focus on NNIs used in arable crop production: imidacloprid, clothianidin, thiamethoxam, acetamiprid, thiacloprid and dinotefuran. Separate inclusion criteria have been developed for each sub-question. Traditional academic and grey literature will be searched for in English language and a searchable databases containing extracted meta-data from relevant included studies will be developed

    Job searching with a history of drugs and crime

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    This article explores the experiences and aspirations of offenders with histories of substance misuse in job searching. The analysis is based upon qualitative data from a localised study of 27 men and two women who were undertaking community-based court orders in Scotland. Their perspectives on job searching, job-readiness and aspirations for sustained employment including the role of self-employment are presented. The article concludes that with adequate support, greater tolerance and flexibility by employers and job searchers could contribute to reducing the vicious cycle of suspicion and dishonesty. Policy action needs to be sustained and possibly augmented to include enterprise training

    Common variants near MC4R are associated with fat mass, weight and risk of obesity.

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    To identify common variants influencing body mass index (BMI), we analyzed genome-wide association data from 16,876 individuals of European descent. After previously reported variants in FTO, the strongest association signal (rs17782313, P = 2.9 x 10(-6)) mapped 188 kb downstream of MC4R (melanocortin-4 receptor), mutations of which are the leading cause of monogenic severe childhood-onset obesity. We confirmed the BMI association in 60,352 adults (per-allele effect = 0.05 Z-score units; P = 2.8 x 10(-15)) and 5,988 children aged 7-11 (0.13 Z-score units; P = 1.5 x 10(-8)). In case-control analyses (n = 10,583), the odds for severe childhood obesity reached 1.30 (P = 8.0 x 10(-11)). Furthermore, we observed overtransmission of the risk allele to obese offspring in 660 families (P (pedigree disequilibrium test average; PDT-avg) = 2.4 x 10(-4)). The SNP location and patterns of phenotypic associations are consistent with effects mediated through altered MC4R function. Our findings establish that common variants near MC4R influence fat mass, weight and obesity risk at the population level and reinforce the need for large-scale data integration to identify variants influencing continuous biomedical traits

    Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits : A Multi-Ethnic Meta-Analysis of 45,891 Individuals

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    J. Kaprio, S. Ripatti ja M.-L. Lokki työryhmien jäseniä.Peer reviewe

    Food and feed safety vulnerabilities in the circular economy

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    Circular economy (CE) is an approach that decouples economic activity from the consumption of finite resources, designs out waste, and instead promotes an economic model based on sharing, leasing, reuse, repair, refurbishment and recycling, in an (almost) closed loop. This extensive literature review identified and categorised CE practices within all stages of the food and feed production chain in Europe to provide an overview of current and envisaged practices. Four broad macro areas were identified within which CE practices are envisaged or currently used in Europe: primary production of food and feed; reducing industrial/manufacturing/processing waste; reducing food and feed waste in wholesale, food retail, catering and households; and reducing food and feed packaging waste. In each macro area, there were a variety of practices of interest regarding emerging risk to plant, animal, human health and the environment. Following consultation with EFSA and wider stakeholders, a focused literature search was carried out to identify emerging risks to plant, animal, human health and the environment from ‘novel foods and feeds within the framework of CE’. The literature showed a bias towards research investigating the suitability of novel feeds in terms of animal productivity parameters rather than on emerging risks of novel food/feed for animal, human, plant health and the environment. Those studies that investigated risk were almost entirely focused on the biological and chemical hazards, risks to health, and environmental impacts of insects as food or feed and the substrates that they are reared on. Emerging risks are characterised and recommendations made for future research. We recommend that future primary research in novel food and feed in the CE focuses on areas other than insect farming, and that there are further investigations into the potential risks associated with importation into the EU of livestock/goods that may have been subject to different restrictions/legislation

    Challenges and recommendations for the development of cultural control of aerial oomycete-associated diseases in protected horticulture

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    A lack of available host resistance due to the emergence of novel plant pathogen isolates and restriction in the use of chemical control means that additional approaches should be considered as part of an integrated pest management (IPM) programme for the control of crop diseases. As each stage of the pathogen lifecycle is influenced by climatic conditions, so modification of the growing environment could be used to help prevent or control disease outbreaks in protected horticulture systems. This is particularly important in Controlled Environment Agriculture (CEA) where product marketing is often reliant on an absence of chemical crop protection products. This review examines the environmental factors affecting plant diseases in protected cropping and summarises the cultural control studies made in relation to manipulating these conditions with regard to disease management using a case study of aerial oomycetes. Aerial oomycete pathogens are responsible for a wide range of commercially important diseases in both protected and field horticultural production. They include the causal agents of downy mildews and some Phytophthora infections and can be rapidly spread via airborne spores. We also discuss the importance of interactions between environmental factors on pathogen biology, outline disease modelling studies which aim to aid outbreak prediction and provide recommendations for the generation and use of effective cultural control procedures in protected horticulture

    Ulcerated palatal tumour in association with elevated serum IgG4

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