The human kindness curriculum: An innovative preclinical initiative to highlight kindness and empathy in medicine.

BackgroundPrior studies have shown a marked drop in empathy among students during their third (clinical) year of medical school. Curricula developed to address this problem have varied greatly in content and have not always been subjected to validated measures of impact.MethodsIn 2015, we initiated a Human Kindness (HK) curriculum for the initial 2 years of medical school. This mandatory 12-h curriculum (6 h/year) included an innovative series of lectures and patient interactions with regard to compassion and empathy in the clinical setting. Both quantitative (Jefferson Scale of Empathy [JSE]) and qualitative data were collected prospectively to evaluate the impact of the HK curriculum.ResultsIn the initial Pilot Year, neither 1st (Group 1) nor 2nd (Group 2) year medical students showed pre-post changes in JSE scores. Substantial changes were made to the curriculum based on faculty and student evaluations. In the following Implementation Year, both the new 1st (Group 3) and the now 2nd year (Group 4) students, who previously experienced the Pilot Year, showed significant improvements in post-course JSE scores; this improvement remained valid across subanalyses of gender, age, and student career focus (e.g., internal medicine, surgery, etc.). Despite the disappointingly flat initial Pilot Year JSE scores, the 3rd year students (Group 2) who experienced only the Pilot Year of the curriculum (i.e., 2nd year students at the time of the Pilot Year) had subsequent JSE scores that did not show the typical decline associated with the clinical years. Students generally evaluated the HK curriculum positively and rated it as being important to their medical education and development as a physician.DiscussionA required preclinical curriculum focused on HK resulted in significant improvements in medical student empathy; this improvement was maintained during the 1st clinical year of training

Jostling for Advantage or Not: Choosing Between Patent Portfolio Races and Ex Ante Licensing

Complex high technology industries are increasingly affected by patent thickets in which firms’ patents mutually block the use of important technologies. Firms facing patent thickets patent intensively to acquire bargaining chips and use licensing to ensure freedom to operate. Such licensing allows rivals to either avoid or resolve hold-up from blocking patents. R&D incentives depend on whether licensing takes place ex ante or ex post. We model the choice between ex ante licensing and entry into patent portfolio races leading to ex post licensing. It is shown that higher degrees of blocking lead firms to license ex post, while stronger product market competition leads firms to license ex ante. Empirical results support these theoretical predictions

EC00-2540 Field Records for Restricted Use Pesticide Applications and Integrated Crop Management by Private Applicators

Private applicators must record their restricted use pesticide (RUP) applications, as required by the Food, Agriculture, Conservation and Trade (FACT) Act of 1990. The USDA Agricultural Marketing Service administers this activity. In Nebraska, RUP application records must be maintained for three years from the date of application. The certified pesticide applicator should retain these RUP records, but must be able to make them accessible for copying by authorized representatives. This booklet is a suggested guide for preliminary or final RUP application records

A study of adverse reaction algorithms in a drug surveillance program

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/110093/1/cptclpt1985156.pd

Gaussian Quantum Information

The science of quantum information has arisen over the last two decades centered on the manipulation of individual quanta of information, known as quantum bits or qubits. Quantum computers, quantum cryptography and quantum teleportation are among the most celebrated ideas that have emerged from this new field. It was realized later on that using continuous-variable quantum information carriers, instead of qubits, constitutes an extremely powerful alternative approach to quantum information processing. This review focuses on continuous-variable quantum information processes that rely on any combination of Gaussian states, Gaussian operations, and Gaussian measurements. Interestingly, such a restriction to the Gaussian realm comes with various benefits, since on the theoretical side, simple analytical tools are available and, on the experimental side, optical components effecting Gaussian processes are readily available in the laboratory. Yet, Gaussian quantum information processing opens the way to a wide variety of tasks and applications, including quantum communication, quantum cryptography, quantum computation, quantum teleportation, and quantum state and channel discrimination. This review reports on the state of the art in this field, ranging from the basic theoretical tools and landmark experimental realizations to the most recent successful developments.Comment: 51 pages, 7 figures, submitted to Reviews of Modern Physic

Witnessing effective entanglement over a 2km fiber channel

We present a fiber-based continuous-variable quantum key distribution system. In the scheme, a quantum signal of two non-orthogonal weak optical coherent states is sent through a fiber-based quantum channel. The receiver simultaneously measures conjugate quadratures of the light using two homodyne detectors. From the measured Q-function of the transmitted signal, we estimate the attenuation and the excess noise caused by the channel. The estimated excess noise originating from the channel and the channel attenuation including the quantum efficiency of the detection setup is investigated with respect to the detection of effective entanglement. The local oscillator is considered in the verification. We witness effective entanglement with a channel length of up to 2km.Comment: 11 pages, 5 figure

Experimental Vacuum Squeezing in Rubidium Vapor via Self-Rotation

We report the generation of optical squeezed vacuum states by means of polarization self-rotation in rubidium vapor following a proposal by Matsko et al. [Phys. Rev. A 66, 043815 (2002)]. The experimental setup, involving in essence just a diode laser and a heated rubidium gas cell, is simple and easily scalable. A squeezing of 0.85+-0.05 dB was achieved

Supersonic turbulence, filamentary accretion,and the rapid assembly of massive stars and disks

We present a detailed computational study of the assembly of protostellar disks and massive stars in molecular clouds with supersonic turbulence. We follow the evolution of large scale filamentary structures in a cluster-forming clump down to protostellar length scales by means of very highly resolved, 3D adaptive mesh refined (AMR) simulations, and show how accretion disks and massive stars form in such environments. We find that an initially elongated cloud core which has a slight spin from oblique shocks collapses first to a filament and later develops a turbulent disk close to the center of the filament. The continued large scale flow that shocks with the filament maintains the high density and pressure within it. Material within the cooling filament undergoes gravitational collapse and an outside-in assembly of a massive protostar. Our simulations show that very high mass accretion rates of up to 10^-2 Msol/yr and high, supersonic, infall velocities result from such filamentary accretion. Accretion at these rates is higher by an order of magnitude than those found in semi-analytic studies, and can quench the radiation field of a growing massive young star.Our simulations include a comprehensive set of the important chemical and radiative processes such as cooling by molecular line emission, gas-dust interaction, and radiative diffusion in the optical thick regime, as well as H2 formation and dissociation. Therefore, we are able to probe, for the first time, the relevant physical phenomena on all scales from those characterizing the clump down to protostellar core.Comment: 35 pages, 17 figures, mnras style, accepted by MNRAS, a high resolution version can be found at http://www.ita.uni-heidelberg.de/~banerjee/TurbulentSF.pdf or http://www.physics.mcmaster.ca/~banerjee/TurbulentSF.pd