Does time constrain affect consumer intention to purchase? A case study with orange/pomegranate juice.

The influence of time pressure on consumer perception may be particularly relevant for the design of food packages. The aim of the present work was to evaluate the influence of time-constraint on results from a rating-based conjoint task, using pomegranate/orange juice as case study. One hundred consumers evaluated the intention to purchase of images of juice bottles, which were designed by manipulating the following variables: bottle design, front-of-pack nutritional information, nutrition claim and processing claim. They were randomly divided into two experimental conditions: control and time-constraint. Consumers with a time-constraint gave significantly higher intention to purchase scores than those in control condition, but time-constraint did not largely modify the way in which consumers evaluated their intention to purchase. In both experimental conditions consumers gave higher intention to purchase scores for bottles with traditional design, which included processing claim and front-of-pack nutritional information. Result suggests that graphic design could help consumers to make healthier food choices.Food: the tree that sustains life. 1648

Morphological Study of Granular-Granular Impact Craters through Time-of-Flight Cameras: from Concept to Automation in Python

Laboratory made granular-granular impact craters have been used as model analogues of planetary impact craters. These kind of craters have been observed and studied using profilometry techniques that allow to retrieve important morphologic features from the impacted surface. In this work, we propose to use a Time-of-Flight camera (Microsoft Kinect One) for the acquisition of depth data. We show comparisons between the typically used technique and the analysis derived from the Time-of-Flight data. We also release craterslab, a Python library developed to automate most of the tasks from the process of studying impact craters produced by granular projectiles hitting on the surface of granular targets. The library is able to acquire, identify, and measure morphological features of impacted surfaces through the reconstruction of 3D topographic maps. Our results show that using a Time-of-Flight camera and automating the data processing with a software library for the systematic study of impact craters can produce very accurate results while reducing the time spent on different stages of the process

Influencia de la inteligencia emocional en la autoeficacia para el liderazgo

Muchas investigaciones se han centrado en analizar y estudiar los beneficios que la inteligencia emocional podría aportar en temas de capacitación y desarrollo de personal. El objetivo de este estudio es comparar las relaciones que existen entre la inteligencia emocional rasgo de los líderes con algunos procesos emocionales; y cómo éstos procesos influyen en otras variables como la autoeficacia para el liderazgo y el desempeño. La muestra fue de 176 estudiantes de Psicología. Cada uno de ellos fue asignado aleatoriamente a los roles de líder y de seguidor, y fueron distribuidos para conformar equipos. El procedimiento de la investigación se desarrolló a lo largo de tres fases. Los resultados del estudio mostraron que la inteligencia emocional rasgo de los líderes influyó significativamente en la autoeficacia para el liderazgo y también predijo el desempeño final del equipo, aunque en este último caso su influencia es parcial. Esta investigación tiene importantes repercusiones para avanzar en la comprensión de las emociones en el lugar de trabajo.Many researches have focused on analyzing and studying the benefits of emotional intelligence could provide in training and staff development issues. The aim of this study is to compare the relationship between trait emotional intelligence of leaders with some emotional processes and how these processes affect other variables such as leadership self-efficacy, self-efficacy and collective effectiveness of a team. The sample comprised 176 students of Psychology. Each person was randomly assigned the roles of leader and follower and they were distributed to form teams. The research procedure was developed over three phases. The results showed that self-efficacy for leadership significantly influenced self-efficacy in the task of the leader and also predicted the team’s final performance; although in the latter case its influence is only partial. This research has important implications for advancing the understanding of emotions in the workplace

Genetic characterization of the red algae Asparagopsis armata and Asparagopsis taxiformis (Bonnemaisoniaceae) from the Azores

info:eu-repo/semantics/publishedVersio

Spanish research on mathematics education

The writing of this text has been partly developed within several research projects: RTI2018-101153-B-C21 and RTI2018-101153-A-C22 (M. Bosch and B. Barquero); PID2019-105601GB-I00 (C. Batanero, M. M. Gea and J.D. Godino); ProID2021010018 (M. Camacho-Machín); EDU2016-75771-P and PID2020-113601GB-I00 (M. C. Cañadas and Enrique Castro); PGC2018-100758-B-I00 (J. M. Chamoso); RTI2018-096547-B-I00 (L. C. Contreras); EDU2017-84979-R (T. F. Blanco); 2021/FQM-226 and PPIIV.4/2021/005 (V. Martín-Molina); PID2020-116514GB-I00 (M. Moreno)

Calculating daily dose in the Observational Medical Outcomes Partnership Common Data Model

Purpose: We aimed to develop a standardized method to calculate daily dose (i.e., the amount of drug a patient was exposed to per day) of any drug on a global scale using only drug information of typical observational data in the Observational Medical Outcomes Partnership Common Data Model (OMOP CDM) and a single reference table from Observational Health Data Sciences And Informatics (OHDSI). Materials and Methods: The OMOP DRUG_STRENGTH reference table contains information on the strength or concentration of drugs, whereas the OMOP DRUG_EXPOSURE table contains information on patients' drug prescriptions or dispensations/claims. Based on DRUG_EXPOSURE data from the primary care databases Clinical Practice Research Datalink GOLD (United Kingdom) and Integrated Primary Care Information (IPCI, The Netherlands) and healthcare claims from PharMetrics® Plus for Academics (USA), we developed four formulas to calculate daily dose given different DRUG_STRENGTH reference table information. We tested the dose formulas by comparing the calculated median daily dose to the World Health Organization (WHO) Defined Daily Dose (DDD) for six different ingredients in those three databases and additional four international databases representing a variety of healthcare settings: MAITT (Estonia, healthcare claims and discharge summaries), IQVIA Disease Analyzer Germany (outpatient data), IQVIA Longitudinal Patient Database Belgium (outpatient data), and IMASIS Parc Salut (Spain, hospital data). Finally, in each database, we assessed the proportion of drug records for which daily dose calculations were possible using the suggested formulas. Results: Applying the dose formulas, we obtained median daily doses that generally matched the WHO DDD definitions. Our dose formulas were applicable to >85% of drug records in all but one of the assessed databases. Conclusion: We have established and implemented a standardized daily dose calculation in OMOP CDM providing reliable and reproducible results

Estudio comparativo de medición entre lecturas visuales y espectrofotométricas en pruebas de susceptibilidad in vitrode aislamientos de candida

Se realizó un estudio de susceptibilidad in vitrofrente a itraconazol, ketoconazol y clotrimazol de 144 cepas de Candida, conservadas y previamente identificadas, aisladas de la cavidad oral de pacientes infectados por elvirus de inmunodeficiencia humana (VIH) con cuadros clínicos de candidiasis orofaríngea (COF). El estudio se llevó a cabo mediante dos metodologías; la primera, utilizando los requerimientos del Clinical and Laboratory Standard Institute (CLSI), en el cual está establecida la lectura visual para determinar los patrones de susceptibilidad; y la segunda, mediante la propuesta de la European Committee on Antibiotic Susceptibility Testing, el cual tiene fijado la lectura espectrofotométrica para eliminar las posibles subjetividades de la metodología del CLSI. Los resultados obtenidos mediante ambas lecturas no mostraron diferencias mayores a dos diluciones en los valores de concentración mínima inhibitoria, y demostraron que ambos métodos se correlacionan y es importante para aquellos laboratorios de pocos recursos económicos.Palabras clave: Susceptibilidad in vitr,; Candida, lectura visual, CLSI, lectura espectrofotométrica, EUCAST azoles, VIH/sida.</p

Synthesis of Structurally Related Coumarin Derivatives as Antiproliferative Agents

A library of structurally related coumarins was generated through synthesis reactions and chemical modification reactions to obtain derivatives with antiproliferative activity both in vivo and in vitro. Out of a total of 35 structurally related coumarin derivatives, seven of them showed inhibitory activity in in vitro tests against Taq DNA polymerase with IC50 values lower than 250 μM. The derivatives 4-(chloromethyl)-5,7-dihydroxy-2H-chromen-2-one (2d) and 4-((acetylthio)methyl)-2-oxo-2H-chromen-7-yl acetate (3c) showed the most promising anti-polymerase activity with IC50 values of 20.7 ± 2.10 and 48.25 ± 1.20 μM, respectively. Assays with tumor cell lines (HEK 293 and HCT-116) were carried out, and the derivative 4-(chloromethyl)-7,8-dihydroxy-2H-chromen-2-one (2c) was the most promising, with an IC50 value of 8.47 μM and a selectivity index of 1.87. In addition, the derivatives were evaluated against Saccharomyces cerevisiae strains that report about common modes of actions, including DNA damage, that are expected for agents that cause replicative stress. The coumarin derivatives 7-(2-(oxiran-2-yl)ethoxy)-2H-chromen-2-one (5b) and 7-(3-(oxiran-2-yl)propoxy)-2H-chromen-2-one (5c) caused DNA damage in S. cerevisiae. The O-alkenylepoxy group stands out as that with the most important functionality within this family of 35 derivatives, presenting a very good profile as an antiproliferative scaffold. Finally, the in vitro antiretroviral capacity was tested through RT-PCR assays. Derivative 5c showed inhibitory activity below 150 μM with an IC50 value of 134.22 ± 2.37 μM, highlighting the O-butylepoxy group as the functionalization responsible for the activity.This research was supported by CONICET (PIP 11220200101091CO 2021-2023), PICT 2017-0785 Type D of the National Agency for Scientific and Technological Promotion, UNSL (PROICO 02-2620), and RGLP from AvH Foundation. E.F.B.-H. thanks CONICET for doctoral fellowship and specially to Graphic Designer Bruna-Haupt L. for his help. H.A.G. thanks CONICET for belonging to the CIC. We wish thank to Dr. Di Marco N. I. for the genetic material gently provided. C.R.P. thanks CONICET for belonging to the CIC and Alexander von Humboldt Foundation for the different subsidies. We appreciate language revision by staff from the Instituto de Lenguas, UNSL, and specially Mg. Rezzano S.F.M. thanks to the Spanish Ministry of Science (research grant BFU2017-83954-R), ACIISI (research grant ProID2017010167), and FIISC (research grant PIFIIS19/04). C.G. thanks Ministerio de Ciencia, Innovación y Universidades (MCIU) of Spain-European Regional Development Fund (ERDF) (PGC2018-094503-B-C22). This work is a part of the cotutelled (UNSL-ULL) Ph.D. of E.F.B.-H.Peer reviewe