Factors Promoting the Entrepreneurship Ecosystem in Heis of India and its Impact on Millennials’ Education

Purpose: The aim of this study is to examine the steps taken by HEIs after the announcement of the startup India campaign by the government in 2015. This research paper will highlight the factors which are responsible to establish an entrepreneurial ecosystem by providing the right education in HEIs f India.   Theoretical framework: Entrepreneurship in educational institutions has increased significantly due to Government’s efforts through the national innovation start-up policy which is not only supporting buddy entrepreneurs but also opening avenues for faculty members. This research paper will highlight the factors which are responsible to establish an entrepreneurial ecosystem by providing the right education in HEIs of India.   Design/methodology/approach: The data has been collected from HEIs of Delhi NCR, India and the same is analysed and interpreted using Statistical Package for Social Sciences (SPSS) software by considering two variables Ecosystem and Education in the Entrepreneurial context. This paper attempts to fill this gap in current research and highlight the role of HEIs in nurturing and shaping future entrepreneurs in India.   Findings: The results through in-person interviews demonstrated that students have a strong willingness to explore this subject however HEIs need to design the right curriculum for better outcomes to nurture buddy entrepreneurs. The result of data analysis shows there exists a significant relationship between education, entrepreneurial ecosystem and career aspirations.   Research, Practical & Social implications: The study suggested that HEIs should have a detailed profile of students’ backgrounds which enables them to design the right strategy for establishing an entrepreneurial ecosystem.   Originality/value: The value of the study is the analysis of the willingness of students towards entrepreneurship as a career and the preparation of HEIs in the implementation of entrepreneurship education. There is an utmost need to design a curriculum by understanding the need of students which can enhance not only their knowledge, skills and abilities but their experience in the world of entrepreneurship

Nietypowe objawy po masażu zatoki szyjnej u chorej z blokiem przedniej wiązki lewej odnogi — opis przypadku

A 65-year-old diabetic and hypertensive woman was admitted for evaluation of syncope. Her baseline electrocardiogram revealed normal sinus rhythm with left anterior hemiblock. Her treadmill test, holter monitoring and external loop recorder examinations were normal. Right sided carotid sinus massage (CSM) revealed 2:1 atrioventricular block (AV) (Mobitz II type) while left sided CSM had no effect. Permanent pacemaker implantation was performed (DDIR, St Jude Medical, USA). Mobitz II type AV block due to CSM reflects enhanced vagal efferent tone on AV node and his bundle fibre.Kobieta w wieku 65 lat z cukrzycą i nadciśnieniem tętniczym została przyjęta na obserwację z powodu omdlenia. W wyjściowym elektrokardiogramie stwierdzono prawidłowy rytm zatokowy z blokiem przedniej wiązki lewej odnogi pęczka Hisa. Wyniki testu wysiłkowego na bieżni oraz zapisy z monitora holterowskiego i zewnętrznego rejestratora pętlowego były prawidłowe. Prawostronny masaż zatoki szyjnej (CSM) ujawnił blok przedsionkowo-komorowy (typu Mobitz II) 2:1, natomiast lewostronny CSM nie spowodował żadnego efektu. Chorej wszczepiono stały stymulator serca (DDIR, St Jude Medical, Stany Zjednoczone). Blok przedsionkowo-komorowy typu Mobitz II spowodowany CSM odzwierciedla wzmożone napięcie części eferentnej nerwu błędnego w węźle przedsionkowo-komorowymi i włóknach odnogi

Młodzieńcze zapalenie tętnic Takayashu objawiające się jako ostry zespół wieńcowy u 10-letniej dziewczynki

A 10 year-old girl was admitted to hospital for evaluation of sudden onset chest pain of three days’ duration. There were no co-morbidities or family history of coronary artery disease. There was a disparity of blood pressure in the upper limbs, while pulses in the lower limbs were barely palpable. Her electrocardiogram revealed ST segment elevation in II, III, and aVF leads. Laboratory tests showed elevated troponin T (0.8 ng/mL), total leukocyte count (13,800/μL), C-reactive protein (94 mg/L), and erythrocyte sedimentation rate (56 mm in first hr). Echocardiography showed mildly impaired left ventricular systolic function with an ejection fraction of 58%. Aortogram showed total occlusion of the brachiocephalic trunk, diffuse thoraco-abdominal coarctation, and osteo-proximal stenosis (80%) of the left renal artery. Coronary angiography revealed total occlusion of the left circumflex artery and tubular lesion of the proximal left anterior descending artery with 70% stenosis. Based on these findings, she was diagnosed to be in the active phase of juvenile Takayasu’s arteritis having acute inferior wall myocardial infarction. Her treadmill test for reversible ischaemia (modified Bruce protocol) was negative, and she was discharged on medication (antiplatelets, corticosteroids, and immunosuppressive agents). Dziewczynka w wieku 10 lat została przyjęta do szpitala w celu wyjaśnienia przyczyny nagłego bólu w klatce piersiowej, który wystąpił 3 dni wcześniej. Pacjentka wcześniej nie chorowała, a wywiad rodzinny w kierunku choroby wieńcowej był ujemny. Stwierdzono różnicę w wartościach ciśnienia tętniczego między prawym a lewym ramieniem, a tętno na kończynach dolnych było ledwo wyczuwalne. W zapisie elektrokardiograficznym widoczne było uniesienie odcinka ST w odprowadzeniach II, III i aVF. W badaniach laboratoryjnych wykazano podwyższone stężenie troponiny T (0,8 ng/ml), liczby leukocytów (13 800/μl), stężenia białka C-reaktywnego (94 mg/l) i wskaźnika opadania erytrocytów (56 mm w 1. godz.). Badanie echokardiograficzne ujawniło łagodne zaburzenie czynności skurczowej lewej komory z frakcją wyrzutową 58%. W aortogramie stwierdzono całkowitą okluzję pnia ramienno-głowowego, rozsiane zwężenia w aorcie piersiowej i brzusznej oraz zwężenie ujścia i proksymalnego odcinka (80%) lewej tętnicy nerkowej. Koronarografia uwidoczniła całkowitą okluzję gałęzi okalającej i cewkowate zwężenie (70%) proksymalnego odcinka tętnicy przedniej zstępującej. Na podstawie wyników badań u chorej rozpoznano aktywną fazę młodzieńczego zapalenia tętnic Takayasu z ostrym zawałem ściany przedniej serca. Wynik przeprowadzonego u chorej ograniczanego objawami testu wysiłkowego na bieżni ruchomej (wg zmodyfikowanego protokołu Bruce’a) był ujemny. Chorą wypisano do domu i zalecono odpowied- nią terapię (leki przeciwpłytkowe, kortykosteroidy i leki immunosupresyjne).

Tunel aortalno-lewokomorowy — rzadka przyczyna szmeru skurczowo-rozkurczowego

Aortico–left ventricular tunnel (ALVT) is a rare congenital paravalvular communication between the aorta and the left ventricle (LV), with few hundred odd cases reported till date. Most commonly the tunnel arises from the right aortic sinus. We herein report a case of AVLT in a 28-year old male where a common pouch, which was communicating to both the left, as well as right aortic sinus, was draining to the left ventricle. He presented with progressive heart failure where a long diastolic murmur was audible. The patient succumbed to death because of progressive cardiac decompensation before surgical correction could have been performed. This is a first ever report of AVLT where proximal chamber as a common sac, communicating with both the left, as well as right aortic sinus, was communicating distally to the left ventricle. Key words- Aortico- left ventricular tunnel, Congenital heart defect, Aortic regurgitation; Diastolic murmur; Cardiac decompensationTunel aortalno-lewokomorowy (AVLT) to występujące bardzo rzadko wrodzone okołozastawkowe połączenie między aortą a lewą komorą. Dotychczas opisano mniej niż 1000 przypadków tej wady serca. Ujście tunelu znajduje się najczęściej w prawej zatoce aortalnej. W artykule przedstawiono przypadek 28-letniego mężczyzny, u którego wspólna kieszonka komunikująca się zarówno z prawą, jak i lewą zatoką aortalną uchodziła do lewej komory. Chory zgłosił się z narastającą niewydolnością serca. W badaniu osłuchowym był słyszalny długi szmer rozkurczowy. Pacjent zmarł z powodu postępu- jącej dekompensacji serca, zanim było możliwe wykonanie chirurgicznego zabiegu naprawczego.  Jest to pierwszy w historii opis AVLT z komorą proksymalną jako wspólną kieszonką, komunikującą się zarówno z prawą, jak i lewą zatoką aortalną uchodzącą do lewej komory.

Ostry zespół wieńcowy u 16-letniego chłopca — opis przypadku

Spontaneous coronary artery dissection is a rare but important cause of acute coronary syndromes in young patients.16-year-old boy presented as acute anterior wall myocardial infarction for which he was thrombolysed. Coronary angiogramshowed spiral luminal filling defects, with extensive contrast staining of proximal left anterior descending arteryand its branches. The patient refused angioplasty, which was advised, and was managed conservatively. Three weekslater he presented with acute coronary syndrome with unstable angina. Repeated angiogram showed complete healingof dissection. The hospital course of the patient was uncomplicated. This shows, that sometimes higher grade dissectionbeside intervention, can respond to conservative management as well.Samoistne rozwarstwienie tętnicy wieńcowej jest rzadką, lecz ważną, przyczyną ostrych zespołów wieńcowych u młodych pacjentów. W niniejszej pracy przedstawiono przypadek 16-letniego chłopca, u którego wystąpił ostry zawał ściany przedniej. Zastosowano leczenie trombolityczne. W koronarografii stwierdzono ubytki wypełnienia w kształcie spiralnym z silnym zakontrastowaniem proksymalnego odcinka gałęzi międzykomorowej przedniej i jej gałęzi. Zalecono wykonanie angioplastyki wieńcowej, jednak chory nie wyraził zgody na zabieg i w związku z tym zastosowano leczenie zachowawcze. Po 3 tygodniach u pacjenta wystąpił ostry zespół wieńcowy w postaci niestabilnej dławicy piersiowej. W wykonanym powtórnie angiogramie stwierdzono całkowite wygojenie rozwarstwienia. Hospitalizacja chorego przebiegała bez powikłań. Opisany przypadek pokazuje, że w niektórych rozwarstwieniach znacznego stopnia można uzyskać dobrą odpowiedź na leczenie zachowawcze bez zabiegów interwencyjnych

Translating a Global Emission-Reduction Framework for Subnational Climate Action: A Case Study from the State of Georgia

Subnational entities are recognizing the need to systematically examine options for reducing their carbon footprints. However, few robust and comprehensive analyses are available that lay out how US states and regions can most effectively contribute. This paper describes an approach developed for Georgia—a state in the southeastern United States called “Drawdown Georgia”, our research involves (1) understanding Georgia’s baseline carbon footprint and trends, (2) identifying the universe of Georgia-specific carbon-reduction solutions that could be impactful by 2030, (3) estimating the greenhouse gas reduction potential of these high-impact 2030 solutions for Georgia, and (4) estimating associated costs and benefits while also considering how the solutions might impact societal priorities, such as economic development opportunities, public health, environmental benefits, and equity. We began by examining the global solutions identified by Project Drawdown. The resulting 20 high-impact 2030 solutions provide a strategy for reducing Georgia’s carbon footprint in the next decade using market-ready technologies and practices and including negative emission solutions. This paper describes our systematic and replicable process and ends with a discussion of its strengths, weaknesses, and planned future research

Household transmission investigation for Corona Virus Disease 2019 (COVID-19) in a rural and urban population of north India.

BackgroundTransmissibility within closed settings, such as households, can provide a strategic way to characterize the virus transmission patterns because the denominator can be well defined. We aimed to characterize the household transmission of Severe Acute Respiratory Syndrome Coronavirus (SARS CoV-2) and its associated risk factors.MethodsThis prospective case-ascertained study was conducted among the household contacts of laboratory-confirmed SARS CoV-2 cases residing in Ballabgarh, Haryana. We enrolled 148 index cases and their 645 household contacts between December 16, 2020 and June 24, 2021. We defined household contact as any person who had resided in the same household as a confirmed COVID-19 case. Baseline data collection and sample collection for real time- reverse transcriptase polymerase chain reaction (RT-PCR) and IgM/IgG against SARS CoV-2 were done on day 1 visit, and followed for a period of 28 days. RT-PCR was repeated on day 14 or whenever the contact is symptomatic and blood sample for serology was repeated on day 28. We estimated household secondary infection rate (SIR) and other epidemiological indicators-median incubation period and serial interval. We employed binomial logistic regression to quantify risk factors associated with infection.ResultsThe household SIR was 30.5% (95% CI: 27.1-34.1%). The secondary clinical attack rate was 9.3% (95% CI: 7.2-11.8). The risk factors that showed higher susceptibility to infection were household contacts who were the primary care giver of the case, whose index cases were symptomatic, those with underlying medical conditions, those living in overcrowded households, who were sharing toilet with the index cases and also who were not wearing a mask when coming in contact with the case. The median (IQR) incubation period was 4 days (4, 5), mean (SD) serial interval 6.4 (±2.2) days, and median (IQR) serial interval 5 days (5, 7).ConclusionHouseholds favour secondary transmission of SARS CoV- 2, hence, index cases are recommended to self-isolate and wear masks; and household contacts to follow strict COVID infection control measures within households when a family member is infected

Non-Standard Errors

In statistics, samples are drawn from a population in a data-generating process (DGP). Standard errors measure the uncertainty in estimates of population parameters. In science, evidence is generated to test hypotheses in an evidence-generating process (EGP). We claim that EGP variation across researchers adds uncertainty: Non-standard errors (NSEs). We study NSEs by letting 164 teams test the same hypotheses on the same data. NSEs turn out to be sizable, but smaller for better reproducible or higher rated research. Adding peer-review stages reduces NSEs. We further find that this type of uncertainty is underestimated by participants

Calibration of the CMS hadron calorimeters using proton-proton collision data at root s=13 TeV

Methods are presented for calibrating the hadron calorimeter system of theCMSetector at the LHC. The hadron calorimeters of the CMS experiment are sampling calorimeters of brass and scintillator, and are in the form of one central detector and two endcaps. These calorimeters cover pseudorapidities vertical bar eta vertical bar ee data. The energy scale of the outer calorimeters has been determined with test beam data and is confirmed through data with high transverse momentum jets. In this paper, we present the details of the calibration methods and accuracy.Peer reviewe

Nations within a nation: variations in epidemiological transition across the states of India, 1990–2016 in the Global Burden of Disease Study

18% of the world's population lives in India, and many states of India have populations similar to those of large countries. Action to effectively improve population health in India requires availability of reliable and comprehensive state-level estimates of disease burden and risk factors over time. Such comprehensive estimates have not been available so far for all major diseases and risk factors. Thus, we aimed to estimate the disease burden and risk factors in every state of India as part of the Global Burden of Disease (GBD) Study 2016