89 New Ultracool Dwarf Co-Moving Companions Identified With The Backyard Worlds: Planet 9 Citizen Science Project

We report the identification of 89 new systems containing ultracool dwarf companions to main sequence stars and white dwarfs, using the citizen science project Backyard Worlds: Planet 9 and cross-reference between Gaia and CatWISE2020. Thirty-two of these companions and thirty-three host stars were followed up with spectroscopic observations, with companion spectral types ranging from M7-T9 and host spectral types ranging from G2-M9. These systems exhibit diverse characteristics, from young to old ages, blue to very red spectral morphologies, potential membership to known young moving groups, and evidence of spectral binarity in 9 companions. Twenty of the host stars in our sample show evidence for higher order multiplicity, with an additional 11 host stars being resolved binaries themselves. We compare this sample's characteristics with those of the known stellar binary and exoplanet populations, and find our sample begins to fill in the gap between directly imaged exoplanets and stellary binaries on mass ratio-binding energy plots. With this study, we increase the population of ultracool dwarf companions to FGK stars by $\sim$42\%, and more than triple the known population of ultracool dwarf companions with separations larger than 1,000 au, providing excellent targets for future atmospheric retrievals.Comment: 61 pages, 11 figures, 11 tables. Accepted for publication in A

World allergy organization anaphylaxis guidance 2020

Anaphylaxis is the most severe clinical presentation of acute systemic allergic reactions. The occurrence of anaphylaxis has increased in recent years, and subsequently, there is a need to continue disseminating knowledge on the diagnosis and management, so every healthcare professional is prepared to deal with such emergencies. The rationale of this updated position document is the need to keep guidance aligned with the current state of the art of knowledge in anaphylaxis management. The World Allergy Organization (WAO) anaphylaxis guidelines were published in 2011, and the current guidance adopts their major indications, incorporating some novel changes. Intramuscular epinephrine (adrenaline) continues to be the first-line treatment for anaphylaxis. Nevertheless, its use remains suboptimal. After an anaphylaxis occurrence, patients should be referred to a specialist to assess the potential cause and to be educated on prevention of recurrences and self-management. The limited availability of epinephrine auto-injectors remains a major problem in many countries, as well as their affordability for some patients

Adaptation in the optical properties of the crystalline lens in the eyes of the Lessepsian migrant Siganus rivulatus

Vision is an important source of information for many animals. The crystalline lens plays a central role in the visual pathway and hence the ecology of fishes. In this study, we tested whether the different light regimes in the Mediterranean and Red Seas have an effect on the optical properties of the lenses in the rivulated rabbitfish, Siganus rivulatus. This species has migrated through the Suez Canal from the Red Sea and established a vital population in the Mediterranean Sea. Longitudinal spherical aberration curves and focal lengths of the fish lenses were measured by laser scans and compared between the two populations. In addition, rivulated rabbitfish from the Mediterranean Sea were exposed to colored light (yellow, green and blue) and unfiltered light for periods of 1 or 13. days to test for short-term adjustments. Lens focal length was significantly longer (3%) in the Rea Sea population. The shorter focal length of the Mediterranean population can be explained as an adaptation to the dimmer light environment, as this difference makes the Mediterranean eyes 5% more sensitive than the eyes of the Red Sea population. The difference may be due to genetic differences or, more likely, adaptive developmental plasticity. Short-term regulatory mechanisms do not seem to be involved

The challenges for nut-allergic consumers of eating out

Background For individuals with a nut allergy, the avoidance of allergens is particularly challenging in situations where they are not preparing their own food. Many allergic reactions occur when eating outside the home. Objective To identify and explore the challenges faced by nut-allergic individuals (NAIs) when they are eating in restaurants and other eating establishments.Methods A qualitative interview study was conducted with 32 adults with a clinical history of allergy to peanuts and/or tree nuts.Results The main strategies that participants adopted to manage the risk of allergic reactions when eating outside the home were avoidance and communication. They avoided types of restaurants, meal courses or particular foods. Seeking familiarity was a key strategy that enabled NAIs to reduce uncertainty and anxiety. Language differences were a major barrier to confident communication about food content. The need to check whether the food on offer may contain nuts was a source of social embarrassment for many participants and the desire to avoid this sometimes led to increased risk taking. Some did not disclose their allergy to restaurant staff as they feared a conservative reaction that would further constrain food choices. NAIs often have to plan where to eat out. The consequent lack of spontaneity was a source of regret to some.Conclusion and Clinical Relevance Communication patterns of nut-allergic adults are often grounded in legitimate everyday social considerations around embarrassment, choice and spontaneity. Education and training strategies are needed that recognize and take account of this. Focusing on communication deficits of NAIs may be unhelpful; responsibility for food safety must be shared with the food industry

Symptom profile and risk factors of anaphylaxis in Central Europe

BACKGROUND: Anaphylaxis is the most severe manifestation of an IgE-dependent allergy. Standardized acquired clinical data from large cohorts of well-defined cases are not available. The aim of this study was to analyse the symptom profile and risk factors of anaphylaxis in a large Central European cohort. METHODS: We acquired data from patients in Germany, Austria and Switzerland who experienced a severe allergic reaction defined by the onset of severe pulmonary and/or severe cardiovascular symptoms. The data were gained via an online questionnaire from 83 medical centres specialized in allergy. Data were collected from 2006 to 2010 and analysed by using a multinomial regression model. RESULTS: A total of 2012 paediatric and adult patients were included into the present analysis. The skin (84%) was the most frequently affected organ followed by the cardiovascular (72%) and the respiratory (68%) system. The regression model analysing the onset of cardiovascular versus respiratory symptoms revealed a strong impact of age (adjusted OR = 6.08; 95% CI, 3.35-11.01; P < 0.001). Furthermore, the elicitor food (adjusted OR = 0.29; 95% CI, 0.21-0.41, P < 0.001) and the presence of atopic diseases (adjusted OR = 0.54; 95% CI, 0.40-0.73, P < 0.001) were significantly associated with the onset of respiratory symptoms. CONCLUSION: Data from individuals who experienced anaphylaxis can support the identification of risk factors. The present study indicates that age, the elicitor itself and the presence of atopic diseases have an impact on the symptom profile of anaphylaxis. Identifying further risk factors of anaphylaxis is of significant importance for clinical practice in the future

Evaluating Crops for a Flexible Summer Fallow Cropping System

Substituting a short-season, spring-planted crop for summer fallow when soil water is sufficient at planting might reduce soil degradation without significantly increasing the risk of crop failure. The objectives of this study were to determine the relationship of crop grain or forage yield to plant available soil water at planting. The study was conducted on silt loam soils in 2004 and 2005 at Sidney, NE, and Akron, CO. A range of soil water levels was established with supplemental irrigation before planting. Four crops [spring triticale (X Triticosecale rimpaui Wittm.) for forage, dry pea (Pisum sativum L.) for grain, proso millet (Panicum miliaceum L.) for grain, and foxtail millet (Setaria italica L. Beauv.) for forage] were no-till seeded into corn (Zea mays L.) residue in a split-plot design with four replications per location. Triticale forage yield increased by 229 kg ha-1 for each centimeter of soil water available at planting in 2004. Foxtail millet forage yield and grain yield of proso millet increased by 399 kg ha-1 cm-1 and 148 kg ha-1 cm-1, respectively, at Akron in 2004. Spring triticale, foxtail millet, and proso millet did not respond to soil water at planting in 2005, when precipitation was above the long-term average. Dry pea did not demonstrate a consistent positive response to soil water availability at planting. Soil water at planting may be a useful indicator of potential yield for selected short-season spring-planted summer crops, particularly when crop production is limited by growing season precipitation