20 research outputs found
First record of <i>Gymnogeophagus terrapurpura</i> (Teleostei: Cichliformes) from Argentina
The genus Gymnogeophagus Miranda Ribeiro 1918 is a diverse genus of geophagin Neotropical cichlids with 1 fossil (Malabarba et al., 2010) and 17 extant species (Malabarba et al., 2015; Loureiro et al., 2016). Species of this genus are endemic to the La Plata basin, the Laguna dos Patos/Merím system, and rio Tramandaí drainage (Malabarba et al., 2015) with one record of G. balzanii in the headwaters of the Guaporé river in the Amazon basin (Lowe-McConnell, 1975). This genus is diagnosed by the presence of a forward-directed spine on top of the first dorsal-fin pterygiophore and by the absence of bony supraneurals (Gosse, 1976). Recently, Gymnogeophagus terrapurpura Loureiro, Zarucki, Malabarba & González-Bergonzoni, 2016 was described as a member of the substrate brooding Gymnogeophagus-rhabdotus-group from the East of the lower Uruguay river basin, the Eastern coastal affluents of the Río de la Plata estuary, and affluents of the Atlantic Ocean in Uruguay. The aim of this work is to report the occurrence of this species in Argentina in tributaries of the Uruguay river near the city of Colón in Entre Ríos province. As part of a revision of the genus Gymnogeophagus from Argentina, we examined existing collection specimens from the San Benito creek and recently collected fresh material from the Perucho Verna and the La Leche creeks, which have been identified as Gymnogeophagus terrapurpura (fig. 1-5).Instituto de Limnología "Dr. Raúl A. Ringuelet
Making visible the invisible. A survey of fish diversity in the Iguazú National Park, Misiones, Argentina
El objetivo de este trabajo es realizar un relevamiento de los peces del Parque Nacional Iguazú y designar aquellas especies vulnerables con valor especial (EVVES). Como resultado de este proyecto se registraron 104 especies, de los cuales 28 son endemismos para la cuenca y 13 representan nuevos registros para la Argentina. Por último, se identificaron 87 especies del PNI con valor especial que representan el 83% del total de peces registrados.The aim of this study is to survey the fish fauna of the Iguazu National Park and designate those vulnerable species with special value (EVVES). As a result of this project 104 species were recorded, of which 28 are endemic to the basin and 13 represent new records for Argentina. Finally, 87 species of PNI with special value representing 83% of total fish recorded were identified.Facultad de Ciencias Naturales y MuseoCentro de Estudios Parasitológicos y de Vectore
Making visible the invisible. A survey of fish diversity in the Iguazú National Park, Misiones, Argentina
El objetivo de este trabajo es realizar un relevamiento de los peces del Parque Nacional Iguazú y designar aquellas especies vulnerables con valor especial (EVVES). Como resultado de este proyecto se registraron 104 especies, de los cuales 28 son endemismos para la cuenca y 13 representan nuevos registros para la Argentina. Por último, se identificaron 87 especies del PNI con valor especial que representan el 83% del total de peces registrados.The aim of this study is to survey the fish fauna of the Iguazu National Park and designate those vulnerable species with special value (EVVES). As a result of this project 104 species were recorded, of which 28 are endemic to the basin and 13 represent new records for Argentina. Finally, 87 species of PNI with special value representing 83% of total fish recorded were identified.Facultad de Ciencias Naturales y MuseoCentro de Estudios Parasitológicos y de Vectore
ADGRL3 (LPHN3) variants predict substance use disorder
Genetic factors are strongly implicated in the susceptibility to develop externalizing syndromes such as attention-deficit/hyperactivity disorder (ADHD), oppositional defiant disorder, conduct disorder, and substance use disorder (SUD). Variants in the ADGRL3 (LPHN3) gene predispose to ADHD and predict ADHD severity, disruptive behaviors comorbidity, long-term outcome, and response to treatment. In this study, we investigated whether variants within ADGRL3 are associated with SUD, a disorder that is frequently co-morbid with ADHD. Using family-based, case-control, and longitudinal samples from disparate regions of the world (n = 2698), recruited either for clinical, genetic epidemiological or pharmacogenomic studies of ADHD, we assembled recursive-partitioning frameworks (classification tree analyses) with clinical, demographic, and ADGRL3 genetic information to predict SUD susceptibility. Our results indicate that SUD can be efficiently and robustly predicted in ADHD participants. The genetic models used remained highly efficient in predicting SUD in a large sample of individuals with severe SUD from a psychiatric institution that were not ascertained on the basis of ADHD diagnosis, thus identifying ADGRL3 as a risk gene for SUD. Recursive-partitioning analyses revealed that rs4860437 was the predominant predictive variant. This new methodological approach offers novel insights into higher order predictive interactions and offers a unique opportunity for translational application in the clinical assessment of patients at high risk for SUD
Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study
Summary
Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally.
Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies
have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of
the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income
countries globally, and identified factors associated with mortality.
Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to
hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis,
exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a
minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical
status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary
intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause,
in-hospital mortality for all conditions combined and each condition individually, stratified by country income status.
We did a complete case analysis.
Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital
diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal
malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome
countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male.
Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3).
Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income
countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups).
Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome
countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries;
p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients
combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11],
p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20
[1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention
(ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety
checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed
(ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of
parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65
[0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality.
Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome,
middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will
be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger
than 5 years by 2030
Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries
Abstract
Background
Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres.
Methods
This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries.
Results
In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia.
Conclusion
This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries
First record of Gymnogeophagus terrapurpura (Teleostei: Cichliformes) from Argentina
The genus Gymnogeophagus Miranda Ribeiro 1918 is a diverse genus of geophagin Neotropical cichlids with 1 fossil (Malabarba et al., 2010) and 17 extant species (Malabarba et al., 2015; Loureiro et al., 2016). Species of this genus are endemic to the La Plata basin, the Laguna dos Patos/Merím system, and rio Tramandaí drainage (Malabarba et al., 2015) with one record of G. balzanii in the headwaters of the Guaporé river in the Amazon basin (Lowe-McConnell, 1975). This genus is diagnosed by the presence of a forward-directed spine on top of the first dorsal-fin pterygiophore and by the absence of bony supraneurals (Gosse, 1976). Recently, Gymnogeophagus terrapurpura Loureiro, Zarucki, Malabarba & González-Bergonzoni, 2016 was described as a member of the substrate brooding Gymnogeophagus-rhabdotus-group from the East of the lower Uruguay river basin, the Eastern coastal affluents of the Río de la Plata estuary, and affluents of the Atlantic Ocean in Uruguay. The aim of this work is to report the occurrence of this species in Argentina in tributaries of the Uruguay river near the city of Colón in Entre Ríos province. As part of a revision of the genus Gymnogeophagus from Argentina, we examined existing collection specimens from the San Benito creek and recently collected fresh material from the Perucho Verna and the La Leche creeks, which have been identified as Gymnogeophagus terrapurpura (fig. 1-5).Fil: Garcia, Ignacio Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Limnología "Dr. Raúl A. Ringuelet". Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. Instituto de Limnología; ArgentinaFil: Puentes, Ariel. No especifica;Fil: Teran, Guillermo Enrique. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico - Tucumán. Unidad Ejecutora Lillo; ArgentinaFil: Koerber, Stefan. No especifica;Fil: Alonso, Felipe. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Salta. Instituto de Bio y Geociencias del NOA. Universidad Nacional de Salta. Facultad de Ciencias Naturales. Museo de Ciencias Naturales. Instituto de Bio y Geociencias del NOA; Argentin
First record of <i>Gymnogeophagus terrapurpura</i> (Teleostei: Cichliformes) from Argentina
The genus Gymnogeophagus Miranda Ribeiro 1918 is a diverse genus of geophagin Neotropical cichlids with 1 fossil (Malabarba et al., 2010) and 17 extant species (Malabarba et al., 2015; Loureiro et al., 2016). Species of this genus are endemic to the La Plata basin, the Laguna dos Patos/Merím system, and rio Tramandaí drainage (Malabarba et al., 2015) with one record of G. balzanii in the headwaters of the Guaporé river in the Amazon basin (Lowe-McConnell, 1975). This genus is diagnosed by the presence of a forward-directed spine on top of the first dorsal-fin pterygiophore and by the absence of bony supraneurals (Gosse, 1976). Recently, Gymnogeophagus terrapurpura Loureiro, Zarucki, Malabarba & González-Bergonzoni, 2016 was described as a member of the substrate brooding Gymnogeophagus-rhabdotus-group from the East of the lower Uruguay river basin, the Eastern coastal affluents of the Río de la Plata estuary, and affluents of the Atlantic Ocean in Uruguay. The aim of this work is to report the occurrence of this species in Argentina in tributaries of the Uruguay river near the city of Colón in Entre Ríos province. As part of a revision of the genus Gymnogeophagus from Argentina, we examined existing collection specimens from the San Benito creek and recently collected fresh material from the Perucho Verna and the La Leche creeks, which have been identified as Gymnogeophagus terrapurpura (fig. 1-5).Instituto de Limnología "Dr. Raúl A. Ringuelet
Analysis of epibiont data in relation with the Debilitated Turtle Syndrome of sea turtles in Chelonia mydas and Lepidochelys olivacea from Concepción coast, Chile
Epibionts on the surface of the skin and shell of a specimen of Chelonia mydas and three Lepidochelys olivacea found floating on the coast of Concepción, Chile, between June 2010 and December 2012, were analyzed. These epibionts were analyzed during the clinical inspection and the tissue changes related to its settlement, with filamentous algae around, were observed. Subsequently, the epibionts were identified by morphological observation. The knowledge about theses epibionts in Chile is reviewed and the potential occurrence of Debilitated Turtle Syndrome (DTS) in these turtles is discussed. The presence of sea turtles in the Chilean coast is considered a casual event, so there is little information on this issue. We propose it is necessary to carry out more studies on the association between turtles and epibionts because their identification, colonizing reptiles’ surface may give relevant information to a better understanding of different diseases, including DTS, that affect these marine reptiles and facilitates the development of strategies intended to recover their populations
Making visible the invisible. A survey of fish diversity in the Iguazú National Park, Misiones, Argentina
El objetivo de este trabajo es realizar un relevamiento de los peces del Parque Nacional Iguazú y designar aquellas especies vulnerables con valor especial (EVVES). Como resultado de este proyecto se registraron 104 especies, de los cuales 28 son endemismos para la cuenca y 13 representan nuevos registros para la Argentina. Por último, se identificaron 87 especies del PNI con valor especial que representan el 83% del total de peces registrados.The aim of this study is to survey the fish fauna of the Iguazu National Park and designate those vulnerable species with special value (EVVES). As a result of this project 104 species were recorded, of which 28 are endemic to the basin and 13 represent new records for Argentina. Finally, 87 species of PNI with special value representing 83% of total fish recorded were identified.Fil: Casciotta, Jorge Rafael. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. División Zoología de Vertebrados; Argentina. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas; ArgentinaFil: Almirón, Adriana Edith. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. División Zoología de Vertebrados; ArgentinaFil: Ciotek, Liliana. Administración de Parques Nacionales; ArgentinaFil: Giorgis, Pablo. Administración de Parques Nacionales; ArgentinaFil: Říčan, Oldřich. University Of South Bohemis; República ChecaFil: Lubomír, Piálek. University Of South Bohemia; República ChecaFil: Klára, Dragová. University Of South Bohemia,; República ChecaFil: Croci, Yasmin. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Montes, Martin Miguel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Estudios Parasitológicos y de Vectores. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. Centro de Estudios Parasitológicos y de Vectores; ArgentinaFil: Iwaszkiw, Juan Miguel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Museo Argentino de Ciencias Naturales “Bernardino Rivadavia”; ArgentinaFil: Puentes, Ariel. No especifica